1. Francisella marina sp. nov., Etiologic Agent of Systemic Disease in Cultured Spotted Rose Snapper (Lutjanus guttatus) in Central America
- Author
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Soto, Esteban, Griffin, Matt J, Morales, Juan Alberto, Calvo, Elías Barquero, de Alexandre Sebastião, Fernanda, Porras, Adrián Lopez, Víquez-Rodríguez, Xindy, Reichley, Stephen R, Rosser, Thomas G, Ware, Cynthia, Byrne, Barbara A, García, Julio C, LaFrentz, Benjamin R, and Camus, Alvin C
- Subjects
Microbiology ,Biological Sciences ,Emerging Infectious Diseases ,Vaccine Related ,Infectious Diseases ,Biotechnology ,Rare Diseases ,Prevention ,Good Health and Well Being ,Animals ,Aquaculture ,Central America ,Cichlids ,DNA ,Bacterial ,Fish Diseases ,Francisella ,Gram-Negative Bacterial Infections ,Phylogeny ,RNA ,Ribosomal ,16S ,aquaculture ,snapper ,fish pathogens ,Medical microbiology - Abstract
Historically, piscine francisellosis in various warm-, temperate-, and cold-water fish hosts has been attributed to Francisella noatunensis From 2015 to 2016, an undescribed Francisella sp. was recovered during mortality events in cultured spotted rose snapper (Lutjanus guttatus) off the Pacific coast of Central America. Despite high mortality and emaciation, limited gross findings were observed in affected fish. Histological examination revealed multifocal granulomatous lesions, with the presence of numerous small, pleomorphic coccobacilli, predominantly in the peritoneum, spleen, kidneys, liver, pancreas, heart, and intestine. Sequencing of an ∼1,400-bp fragment of the 16S rRNA gene demonstrated these isolates to be most similar (99.9% identity) to Francisella sp. isolate TX077308 cultured from seawater in the Gulf of Mexico, while sharing
- Published
- 2018