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12. Dermal Exposure of Morinda Citrifolia Linn. Fruit Extract Coated Gold Nanoparticles: Effects on Haematological and Biochemical Parameters in Wistar Rats

Author

In-house, Pawar, A. R., Rajurkar, S. R., Ballurkar, B. V., Naraladkar, B. W., Jadhav, Nitin D., Sachin, Bhalchim, In-house, Pawar, A. R., Rajurkar, S. R., Ballurkar, B. V., Naraladkar, B. W., Jadhav, Nitin D., and Sachin, Bhalchim

Abstract

The present study was carried out to evaluate the effect of Morinda citrifolia fruit extract coated gold nanoparticles on subacute dermal toxicity in wistar rats. Gold nanoparticles (GNPs) were synthesized by biological reduction (green synthesis) of chloroauric acid (HAuCl4.3H2O) with Azadirachta Indica (Neem) 5% leaf extract1. The nanoparticles characterized and were confirmed by colour changes from pale yellow to ruby red. These nanoparticles were coated with Morinda citrifolia fruit extract (McFE)1. The toxicity was evaluated in 50 wistar rats of either sex and randomly assigned to five groups. One group was considered healthy, three groups received dermal application of the combination of 1 mg/kg GNPs with 150 mg/kg McFE (Low dose), 2 mg/kg GNPs with 300 mg/kg McFE (Medium dose) and 4 mg/kg GNPs with 600 mg/kg McFE (High dose) dermal application for 28 days. The last group was considered as satellite group which received 8 mg/ kg GNPs with 1200 mg/kg McFE and animals were observed for extra 14 days beyond trial period for post withdrawal effect. There were no abnormal behavioral signs and no any alteration observed on skin throughout the experimental period. Hematological parameters showed no significant variations as a sign of toxicity except hike in neutrophil count and compensatory increase in TEC count on 28th day of entire treatment period but not in a dose dependent manner. Similarly, serum biochemical values showed a hike in ALT and AST in McFE coated GNPs groups. However, hike in BUN values in the experiment was observed to be non-dose dependent and a significant increase in creatinine dose independently on 28th days was observed. There was non-significant increase in total protein on day 14 was observed in the experiment. There was no significant toxicity in entire dosage, from hematology aspect but slight immune stimulation seen up-to 14th day of experiment (neutrophil) in McFE coated GNPs doses with no relation to dose and coating. However, in serum

Published
2020

13. Dermal Exposure of Morinda Citrifolia Linn. Fruit Extract Coated Gold Nanoparticles: Effects on Haematological and Biochemical Parameters in Wistar Rats

Author

Pawar, A. R., Rajurkar, S. R., Ballurkar, B. V., Naraladkar, B. W., Jadhav, Nitin D., Sachin, Bhalchim, Pawar, A. R., Rajurkar, S. R., Ballurkar, B. V., Naraladkar, B. W., Jadhav, Nitin D., and Sachin, Bhalchim

Abstract

The present study was carried out to evaluate the effect of Morinda citrifolia fruit extract coated gold nanoparticles on subacute dermal toxicity in wistar rats. Gold nanoparticles (GNPs) were synthesized by biological reduction (green synthesis) of chloroauric acid (HAuCl4.3H2O) with Azadirachta Indica (Neem) 5% leaf extract1. The nanoparticles characterized and were confirmed by colour changes from pale yellow to ruby red. These nanoparticles were coated with Morinda citrifolia fruit extract (McFE)1. The toxicity was evaluated in 50 wistar rats of either sex and randomly assigned to five groups. One group was considered healthy, three groups received dermal application of the combination of 1 mg/kg GNPs with 150 mg/kg McFE (Low dose), 2 mg/kg GNPs with 300 mg/kg McFE (Medium dose) and 4 mg/kg GNPs with 600 mg/kg McFE (High dose) dermal application for 28 days. The last group was considered as satellite group which received 8 mg/ kg GNPs with 1200 mg/kg McFE and animals were observed for extra 14 days beyond trial period for post withdrawal effect. There were no abnormal behavioral signs and no any alteration observed on skin throughout the experimental period. Hematological parameters showed no significant variations as a sign of toxicity except hike in neutrophil count and compensatory increase in TEC count on 28th day of entire treatment period but not in a dose dependent manner. Similarly, serum biochemical values showed a hike in ALT and AST in McFE coated GNPs groups. However, hike in BUN values in the experiment was observed to be non-dose dependent and a significant increase in creatinine dose independently on 28th days was observed. There was non-significant increase in total protein on day 14 was observed in the experiment. There was no significant toxicity in entire dosage, from hematology aspect but slight immune stimulation seen up-to 14th day of experiment (neutrophil) in McFE coated GNPs doses with no relation to dose and coating. However, in serum

Published
2020

14. Study of Brain Imaging in Accelerated Hypertension

Author

Patange, Aparna Prasanna, primary, Patel, Pavan Dahyabhai, additional, Nair, Shruti Shrinivas, additional, Patel, Dahyabhai Muljibhai, additional, Botre, Amit, additional, Ravan, Aditya, additional, Jadhav, Nitin, additional, and Bhosale, Tejas, additional

Published
2019
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15. OP-01: RELATIONSHIP BETWEEN MATERNAL HEALTH SERVICES AND MATERNAL DEATHS DUE TO DIRECT OBSTETRIC CAUSES OVER FIVE-YEAR PERIOD IN KARNATAKA: AN EQUITY FOCUSED EVALUATION

Author

Bhojani, Upendra, Soors, Werner, Yellappa, Vijayashree, Ahluwalia, Aneesha, Himanshu, M, Kumar, Anil, Chandrashekarappa, BG, Kumar, Praveen, Suresh, M, Uma, DT, Hallad, Jyoti S, Golandaj, Javeed A, Kar, Arin, Krishanamurthy, J, Ramesh, BM, Deshpande, RV, Pundappanavar, BI, Dehury, Ranjit Kumar, Nandi, Sulakshana, Sinha, Dipa, Joshi, Deepika, Dubey, Rajesh, Prasad, Vandana, Srivastava, Swati, Bose, Montu, Karan, Anup, Selvaraj, Sakthivel, Bhatt, Pallav, Sandhu, Digvijay Singh, Srinivasan, Varadharajan, Zwanikken, Prisca, Carasso, Barbara Kashi, Das, Arupa, Saha, Ananya, Talati, Kandarp N, Nimbalkar, Somashekhar, Phatak, Ajay, Patel, Dipen, Seshadri, Shreelata Rao, Bhor, Nilanjan, Parab, Suraj, Kumar, Pankaj, Ambadekar, Nitin N, Zodpey, Sanjay P, Shubha, DB, Kaur, Navneet, Mahabalaraju, DK, Dehury, Parthsarathi, Jaya, Sreejini, Dasgupta, Rajib, Garg, Samir, Sahu, Sangeeta, Mahobe, Reeti, Khewar, Anju, Rizu, K, Raman, VR, Sheikh, Kabir, Scott, Kerry, George, Asha, Garimella, Surekha, Mondal, Shinjini, Patel, Gupteswar, Ved, Rajani, Nanda, Prabodh, Dewangan, Mukesh, Jadhav, Nitin, Marathe, Shweta, Yakundi, Deepali, Patil, Hemraj, Adsul, Neha, Nair, Manju S, Naidu, V Nagarajan, Patel, Kripalini, Saluja, Deepika, Kilaru, Asha, Saligram, Prasanna, Nagavarapu, Sudha, Giske, Anna, Anitha, PH, Godwin, SK, John, Denny, Chatterjee, Prabir, Kashyap, Sham N, Prinja, Shankar, Bahuguna, Pankaj, Balasubramaniam, Deepak, Sharma, Atul, Kumar, Rajesh, Kandamuthan, Subodh, Madhireddi, Ramya, Srinidhi, V, Iyer, Aditi, Sreevathsa, Anuradha, Shankar, Mridula, Bhan, Nandita, Sivaram, Sharmada, Madhira, Pavitra, Singh, Pooja, Newton-Lewis, Tom, Saith, Ruhi, Singh, Prabal, Kak, Mohini, Gill, Kaveri, Tunyi, Sao, Changkija, Nandira, Mullen, Patrick, Pradyumna, Adithya, Ghosh, Upasona, Bose, Shibaji, Bramhachari, Rittika, Mondol, Sabyasachi, Vadrevu, Lalitha, Kanjilal, Barun, Sarkar, Amitabha, Goel, Prankul, Sharma, Nishant, Singh, Shweta, Mathur, Kopal, Bothra, Vinay, Mairembam, Dilip Singh, Gupta, Shikha, Sarangi, Biraj, Atkuri, Ramani, Thomas, Deborah, Rath, Alison Dembo, Tripathi, Narayan, Kerketta, Fidius, Sadhana, SM, Rao, Krishna Dipankar, Sen, Gita, Varghese, Joe, John, Priya, Hajra, Gitanjali, Dutta, Arijita, Mubangizi, Vincent, Mandal, Sabyasachi, Rathore, Jalam Singh, Meena, Ratan Kumar, Ayyub, Mohammad, and Singh, Anjali

Subjects
Equity in Maternal Health Care, Researching Health Inequities, Migration, Poverty & Health of Urban Populations, Insurance & Equitable Financial Protection for Health, From Research to Better Policy & Practice, Acknowledgements, Role of Healthcare Expenses in Equitable Health Care, Subject Index, Article, Food, Nutrition & Health, Poster Presentations, Policy & Health Equity, Editorial, Health Systems & Training Initiatives, Ephp Abstracts, Oral Presentations, Fostering Community Engagement in Health Services, Analysing Local Actors & Processes, Towards Equitable Healthcare Provision
Published
2016

21. PL and ESR Study on UVB-Emitting Gadolinium-Doped BaMgAl10O17 Hexagonal Phase Obtained by Combustion Synthesis.

Author

Singh, Vijay, Singh, N., Pathak, M. S., Watanabe, S., Gundu Rao, T. K., Jadhav, Nitin A., and Kwon, Young-Wan

Subjects
PHOTOLUMINESCENCE, ELECTRON paramagnetic resonance, PHOSPHORS, BARIUM compounds, GADOLINIUM
Abstract

A series of Gd3+-doped BaMgAl10O17 phosphors have been successfully synthesized using a low-temperature solution combustion method. The crystal structure and phase purity of the samples were characterized using x-ray powder diffraction analysis. The optimal concentration of Gd3+ dopant in BaMgAl10O17 was determined through measurements of the photoluminescence spectra of the phosphors. All phosphors showed narrowband UVB emission at 313 nm with excitation wavelength at 272 nm. Relatively dominant electron spin resonance (ESR) lines were observed with geff ≈ 1.98. 2.7, 4.2, and 5.95 in phosphors with low concentration of dopant Gd3+ ion. At higher dopant concentrations, the spectrum appeared to be U-like with prominent lines at geff ≈ 1.99, 2.7, 4.2, and 5.94. Distortions in the neighborhood of Gd3+ ion led to ESR lines in the low-field region of the spectrum. [ABSTRACT FROM AUTHOR]

Published
2018
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23. Tuberculosis Pathways to Care and Transmission of Multidrug-Resistance in India.

Author

Atre, Sachin R., Jagtap, Jayshri D., Faqih, Mujtaba I., Dumbare, Yogita K., Sawant, Trupti U., Ambike, Sunil L., Bhawalkar, Jitendra S., Bharaswadkar, Sandeep K., Jogewar, Padmaja K., Adkekar, Ramji S., Hodgar, Balasaheb P., Jadhav, Vaishali, Mokashi, Nitin D., Golub, Jonathan E., Dixit, Avika, and Farhat, Maha R.

Subjects
TUBERCULOSIS, SYMPTOMS, MEDICAL care
Abstract

The article presents the discussion on tuberculosis pathways to care and transmission of multidrug-resistance in India asking about the duration from symptom onset to the first healthcare encounter, diagnosis, and initiation of treatment.

Published
2022
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24. Primary tubercular osteomyelitis affecting the mandibular condyle - A case report.

Author

Gupta, Aishwarya, Jadhav, Anendd, Bhola, Nitin, Mishra, Apoorva, and Simre, Saurabh

Subjects
MANDIBULAR condyle, TUBERCULOMA, OSTEOMYELITIS, TUBERCULIN test, TUBERCULOUS meningitis, POLYMERASE chain reaction
Abstract

Rationale: Primary orofacial tuberculosis (TB) accounts for <3% of all cases of TB. TB of the mandibular condyle is often misdiagnosed owing to its rarity. Patient Concerns: This report presents a 19-year-old female who presented with a painful swelling over the right preauricular region. The radiographic evaluation suggested a diagnosis of suppurative osteomyelitis of the condyle. Diagnosis: Clinically, the aetiology of the swelling was considered as infective. The histopathological examination of the resected specimen showed tuberculous granuloma and the polymerase chain reaction came positive. This confirms the diagnosis of tubercular osteomyelitis. Mantoux test and sputum acid-fast bacilli were found to be negative. Treatment: The patient was subjected to sequestrectomy with high condylectomy and systemic multidrug antitubercular regimen for 6 months. Outcomes: There was a resolution of infection postoperatively with subsequent regeneration of healthy bone. Take-away Lessons: Early identification and prompt diagnosis is imperative for better treatment outcomes. [ABSTRACT FROM AUTHOR]

Published
2022
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28. Simultaneous removal of selenite and selenate from drinking water using mesoporous activated alumina.

Author

Meher, Alok Kumar, Jadhav, Asmita, Labhsetwar, Nitin, and Bansiwal, Amit

Subjects
DRINKING water, FREUNDLICH isotherm equation, WATER use, ADSORPTION isotherms, ADSORPTION capacity
Abstract

The present study reports detailed evaluation of mesoporous activated alumina (MAA) for simultaneous removal of two hazardous inorganic species of selenium, namely selenite and selanate, from drinking water. MAA was used after washing with deionized water followed by drying at 110 °C for 8 h. The material was characterized using pXRD, FTIR, zeta potential, SEM and BET surface area measurements. Batch adsorption studies were performed, and various adsorption isotherms and kinetic parameters were computed to delineate the mechanism of adsorption. It was observed that Freundlich adsorption isotherm was the best-fit model for both the species of selenium. The adsorption capacity obtained from Freundlich isotherm for selenite and selenate was found to be 9.02 µg g−1 and 5.38 µg g−1, respectively. Kinetics studies revealed that adsorption of selenite follows pseudo-second-order model, whereas selenate adsorption follows pseudo-first-order model. The efficiency of the material was also evaluated at different pH and in the presence of different competitive co-ions, which confirms efficacy of MAA at near-neutral pH and lower concentrations of competitive co-ions. Negligible changes in the pH were observed during the course of adsorption. Further, the saturated adsorbent was subjected to regeneration and reuse studies up to ten cycles, showing insignificant reduction in adsorption efficiency of the adsorbent during few initial cycles. The study infers the effectiveness of MAA as a potential adsorbent for drinking water treatment contaminated with selenium. [ABSTRACT FROM AUTHOR]

Published
2020
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29. Etender Notice No-01_2022-2023_04

Subjects
Business, international
Abstract

Contract awarded for etender notice no-01_2022-2023_04 Bidder Name Mrs. Rina bhagwan jadhav Nitin prakash raut Contractor name : HARSH CONSTRUCTION Implementing agency : Rdd-Ceo-Nashik, Nashik-Dy. Ceo V.P., Kalwan, Athambe Country [...]

Published
2023

32. Researchers Submit Patent Application, 'Authentication Management', for Approval (USPTO 20180276368)

Subjects
International Business Machines Corp. -- Intellectual property -- Management, Office equipment, Patents, Computer industry -- Intellectual property, Company business management, Patent/copyright issue, Microcomputer industry, Computer industry, Computers, News, opinion and commentary
Abstract

2018 OCT 17 (VerticalNews) -- By a News Reporter-Staff News Editor at Computer Weekly News -- From Washington, D.C., VerticalNews journalists report that a patent application by the inventors Dhoot, [...]

Published
2018

33. Patent Application Titled 'Authentication Management' Published Online (USPTO 20180247051)

Subjects
International Business Machines Corp. -- Intellectual property -- Management, Patents, Computer industry -- Intellectual property, Company business management, Patent/copyright issue, Microcomputer industry, Computer industry, Computers
Abstract

2018 SEP 18 (VerticalNews) -- By a News Reporter-Staff News Editor at Information Technology Newsweekly -- According to news reporting originating from Washington, D.C., by VerticalNews journalists, a patent application [...]

Published
2018

38. Patent Issued for Authentication Management (USPTO 9996687)

Subjects
International Business Machines Corp. -- Intellectual property -- Reports -- Management, Office equipment -- Reports, Patents -- Reports, Computer industry -- Intellectual property -- Reports, Company business management, Patent/copyright issue, Microcomputer industry, Computer industry, Computers
Abstract

2018 JUN 26 (VerticalNews) -- By a News Reporter-Staff News Editor at Information Technology Newsweekly -- From Alexandria, Virginia, VerticalNews journalists report that a patent by the inventors Dhoot, Akash [...]

Published
2018

39. Patent Application Titled 'Semiconductor Wafer with Nonstick Seal Region' Published Online (USPTO 20150303102)

Subjects
International Business Machines Corp. -- Intellectual property, Patents, Computer industry -- Intellectual property, Patent/copyright issue, Microcomputer industry, Computer industry, Computers, News, opinion and commentary
Abstract

2015 NOV 11 (VerticalNews) -- By a News Reporter-Staff News Editor at Computer Weekly News -- According to news reporting originating from Washington, D.C., by VerticalNews journalists, a patent application [...]

Published
2015

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