Search

Your search keyword '"Canivet, Clémence M."' showing total 17 results
Start Over Author "Canivet, Clémence M." Search Limiters Full Text Publication Year Range Last 10 years
17 results on '"Canivet, Clémence M."'

3. Validation of the Blood Test MACK-3 for the Noninvasive Diagnosis of Fibrotic Nonalcoholic Steatohepatitis: An International Study With 1924 Patients

Author

Canivet, Clémence M., Zheng, Ming-Hua, Qadri, Sami, Vonghia, Luisa, Chuah, Kee-Huat, Costentin, Charlotte, George, Jacob, Armandi, Angelo, Adams, Leon A., Lange, Naomi F., Blanchet, Odile, Moal, Valérie, Younes, Ramy, Roux, Marine, Chan, Wah-Kheong, Sturm, Nathalie, Eslam, Mohammed, Bugianesi, Elisabetta, Wang, Zhengyi, Dufour, Jean-François, Francque, Sven, Yki-Järvinen, Hannele, Zheng, Kenneth I., and Boursier, Jérôme

Published
2023
Full Text
View/download PDF

5. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications

Author

Boursier, Jérôme, Canivet, Clémence M., Costentin, Charlotte, Lannes, Adrien, Delamarre, Adèle, Sturm, Nathalie, Le Bail, Brigitte, Michalak, Sophie, Oberti, Frédéric, Hilleret, Marie-Noelle, Irles-Depé, Marie, Fouchard, Isabelle, Hermabessiere, Paul, Barthelon, Justine, Calès, Paul, Cariou, Bertrand, de Ledinghen, Victor, and Roux, Marine

Published
2023
Full Text
View/download PDF

6. Reliability Criteria of Two-Dimensional Shear Wave Elastography: Analysis of 4277 Measurements in 788 Patients

Author

Paisant, Anita, Lemoine, Sylvain, Cassinotto, Christophe, de Lédinghen, Victor, Ronot, Maxime, Irlès-Depé, Marie, Vilgrain, Valérie, Le Bail, Brigitte, Paradis, Valérie, Canivet, Clémence M., Michalak, Sophie, Rousselet, Marie-Christine, Rautou, Pierre-Emmanuel, Lebigot, Jérôme, Hunault, Gilles, Crouan, Anne, Aubé, Christophe, and Boursier, Jérôme

Published
2022
Full Text
View/download PDF

11. Systematic screening for advanced liver fibrosis in patients with coronary artery disease: The CORONASH study

Author

Thévenot, Thierry, primary, Vendeville, Sophie, additional, Weil, Delphine, additional, Akkouche, Linda, additional, Calame, Paul, additional, Canivet, Clémence M., additional, Vanlemmens, Claire, additional, Richou, Carine, additional, Cervoni, Jean-Paul, additional, Seronde, Marie-France, additional, Di Martino, Vincent, additional, and Boursier, Jérôme, additional

Published
2022
Full Text
View/download PDF

13. Non-invasive tests accurately stratify patients with NAFLD based on their risk of liver-related events

Author

Intercept Pharmaceuticals, Ekstedt, Mattias [0000-0002-5590-8601], Bonacci, Martin [0000-0002-4528-8066], Cure, Sandrine [0000-0002-8296-0771], Kechagias, Stergios [0000-0001-7614-739X], Boursier, Jerome, Hagström, Hannes, Ekstedt, Mattias, Moreau, Clemence, Bonacci, Martin, Cure, Sandrine, Ampuero, Javier, Nasr, Patrik, Tallab, Lilian, Canivet, Clémence M., Kechagias, Stergios, Sánchez-Torrijos, Yolanda, Dincuff, Eloise, Lucena-Valera, Ana, Roux, Marine, Riou, Jeremie, Trylesinski, Aldo, Romero-Gómez, Manuel, Intercept Pharmaceuticals, Ekstedt, Mattias [0000-0002-5590-8601], Bonacci, Martin [0000-0002-4528-8066], Cure, Sandrine [0000-0002-8296-0771], Kechagias, Stergios [0000-0001-7614-739X], Boursier, Jerome, Hagström, Hannes, Ekstedt, Mattias, Moreau, Clemence, Bonacci, Martin, Cure, Sandrine, Ampuero, Javier, Nasr, Patrik, Tallab, Lilian, Canivet, Clémence M., Kechagias, Stergios, Sánchez-Torrijos, Yolanda, Dincuff, Eloise, Lucena-Valera, Ana, Roux, Marine, Riou, Jeremie, Trylesinski, Aldo, and Romero-Gómez, Manuel

Abstract

[Background & Aims] Previous studies on the prognostic significance of non-invasive liver fibrosis tests in non-alcoholic fatty liver disease (NAFLD) lack direct comparison to liver biopsy. We aimed to evaluate the prognostic accuracy of fibrosis-4 (FIB4) and vibration-controlled transient elastography (VCTE), compared to liver biopsy, for the prediction of liver-related events (LREs) in NAFLD., [Methods] A total of 1,057 patients with NAFLD and baseline FIB4 and VCTE were included in a multicenter cohort. Of these patients, 594 also had a baseline liver biopsy. The main study outcome during follow-up was occurrence of LREs, a composite endpoint combining cirrhosis complications and/or hepatocellular carcinoma. Discriminative ability was evaluated using Harrell’s C-index., [Results] FIB4 and VCTE showed good accuracy for the prediction of LREs, with Harrell’s C-indexes >0.80 (0.817 [0.768-0.866] vs. 0.878 [0.835-0.921], respectively, p = 0.059). In the biopsy subgroup, Harrell’s C-indexes of histological fibrosis staging and VCTE were not significantly different (0.932 [0.910-0.955] vs. 0.881 [0.832-0.931], respectively, p = 0.164), while both significantly outperformed FIB4 for the prediction of LREs. FIB4 and VCTE were independent predictors of LREs in the whole study cohort. The stepwise FIB4-VCTE algorithm accurately stratified the risk of LREs: compared to patients with “FIB4 <1.30”, those with “FIB4 ≥1.30 then VCTE <8.0 kPa” had similar risk of LREs (adjusted hazard ratio [aHR] 1.3; 95% CI 0.3–6.8), whereas the risk of LREs significantly increased in patients with “FIB4 ≥1.30 then VCTE 8.0-12.0 kPa” (aHR 3.8; 95% CI 1.3–10.9), and even more for those with “FIB4 ≥1.30 then VCTE >12.0 kPa” (aHR 12.4; 95% CI 5.1–30.2)., [Conclusion] VCTE and FIB4 accurately stratify patients with NAFLD based on their risk of LREs. These non-invasive tests are alternatives to liver biopsy for the identification of patients in need of specialized management.

Published
2022

14. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications

Author

Boursier, Jérôme, primary, Canivet, Clémence M., additional, Costentin, Charlotte, additional, Lannes, Adrien, additional, Delamarre, Adèle, additional, Sturm, Nathalie, additional, Le Bail, Brigitte, additional, Michalak, Sophie, additional, Oberti, Frédéric, additional, Hilleret, Marie-Noelle, additional, Irles-Depé, Marie, additional, Fouchard, Isabelle, additional, Hermabessiere, Paul, additional, Barthelon, Justine, additional, Calès, Paul, additional, Cariou, Bertrand, additional, de Ledinghen, Victor, additional, and Roux, Marine, additional

Published
2022
Full Text
View/download PDF

17. Investigation of Inherited Chromosomally Integrated Human Herpesvirus-6A+ and -6B+ in a Patient with Ulipristal Acetate-Induced Fulminant Hepatic Failure.

Author

Izquierdo, Laure, Canivet, Clémence M., De Martin, Eleonora, Antonini, Teresa M., Roque-Afonso, Anne-Marie, Coilly, Audrey, and Deback, Claire

Subjects
*LIVER failure, *DRUG side effects, *PROGESTERONE, *PROGESTERONE receptors, *HEREDITY, *HAIR follicles, *HUMAN herpesvirus-6
Abstract

Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are capable of activating iciHHV-6 in tissues, the consequences of which are poorly understood. We report herein a case of a woman with iciHHV-6A+ and iciHHV-6B+, who developed ulipristal acetate (a selective progesterone receptor modulator)-induced fulminant hepatic failure that required liver transplantation. We confirmed the presence of ~one copy per cell of both HHV-6A and HHV-6B DNA in her hair follicles using multiplex HHV-6A/B real-time PCR and demonstrated the Mendelian inheritance of both iciHHV-6A and iciHHV-6B in her family members over three generations. Because of the rarity of this presentation, we discuss herein the possible links between reactivated HHV-6 from iciHHV-6A and/or iciHHV-6B and adverse drug reactions, suggesting that iciHHV-6 could be screened before the introduction of any hepatotoxic drugs to exclude HHV-6 active disease or combined idiosyncratic drug-induced liver injury in these patients. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results