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Your search keyword '"Bunnell, Craig A."' showing total 18 results
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18 results on '"Bunnell, Craig A."'

1. Neuroinvasive Bacillus cereus Infection in Immunocompromised Hosts: Epidemiologic Investigation of 5 Patients With Acute Myeloid Leukemia

Author

Little, Jessica S, primary, Coughlin, Cassie, additional, Hsieh, Candace, additional, Lanza, Meaghan, additional, Huang, Wan Yi, additional, Kumar, Aishwarya, additional, Dandawate, Tanvi, additional, Tucker, Robert, additional, Gable, Paige, additional, Vazquez Deida, Axel A, additional, Moulton-Meissner, Heather, additional, Stevens, Valerie, additional, McAllister, Gillian, additional, Ewing, Thomas, additional, Diaz, Maria, additional, Glowicz, Janet, additional, Winkler, Marisa L, additional, Pecora, Nicole, additional, Kubiak, David W, additional, Pearson, Jeffrey C, additional, Luskin, Marlise R, additional, Sherman, Amy C, additional, Woolley, Ann E, additional, Brandeburg, Christina, additional, Bolstorff, Barbara, additional, McHale, Eileen, additional, Fortes, Esther, additional, Doucette, Matthew, additional, Smole, Sandra, additional, Bunnell, Craig, additional, Gross, Anne, additional, Platt, Dana, additional, Desai, Sonali, additional, Fiumara, Karen, additional, Issa, Nicolas C, additional, Baden, Lindsey R, additional, Rhee, Chanu, additional, Klompas, Michael, additional, and Baker, Meghan A, additional

Published
2024
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2. 1452. Neuroinvasive Bacillus Cereus Infection Amongst Immunocompromised Patients: Epidemiological Investigation of 5 Cases in Patients with Acute Myeloid Leukemia

Author

Little, Jessica S, primary, Coughlin, Cassie, additional, Hsieh, Candace C R, additional, Lanza, Meaghan, additional, Huang, Wanyi, additional, Kumar, Aishwarya, additional, Dandawate, Tanvi, additional, Tucker, Robert, additional, Winkler, Marisa, additional, Pecora, Nicole, additional, Luskin, Marlise, additional, Woolley, Ann E, additional, Issa, Nicolas C, additional, Baden, Lindsey R, additional, Brandeburg, Christina, additional, Bolstorff, Barabara, additional, Fortes, Esther D, additional, Doucette, Matthew, additional, McHale, Eileen, additional, Bunnell, Craig, additional, Platt, Dana, additional, Desai, Sonali, additional, Gross, Anne, additional, Fiumara, Karen, additional, Rhee, Chanu, additional, Klompas, Michael, additional, and Baker, Meghan, additional

Published
2023
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6. Age and the Risk of Paclitaxel-Induced Neuropathy in Women with Early-Stage Breast Cancer (Alliance A151411): Results from 1,881 Patients from Cancer and Leukemia Group B (CALGB) 40101

Author

Barginear, Myra, primary, Dueck, Amylou C., additional, Allred, Jacob B., additional, Bunnell, Craig, additional, Cohen, Harvey J., additional, Freedman, Rachel A., additional, Hurria, Arti, additional, Kimmick, Gretchen, additional, Le-Rademacher, Jennifer G., additional, Lichtman, Stuart, additional, Muss, Hyman B., additional, Shulman, Lawrence N., additional, Copur, M. Sitiki, additional, Biggs, David, additional, Ramaswamy, Bhuvaneswari, additional, Lafky, Jacqueline M., additional, and Jatoi, Aminah, additional

Published
2018
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8. Implementation of Surgeon-Initiated Gene Expression Profile Testing (Oncotype DX) Among Patients With Early-Stage Breast Cancer to Reduce Delays in Chemotherapy Initiation

Author

Losk, Katya, primary, Freedman, Rachel A., additional, Lin, Nancy U., additional, Golshan, Mehra, additional, Pochebit, Stephen M., additional, Lester, Susan C., additional, Natsuhara, Kelsey, additional, Camuso, Kristen, additional, King, Tari A., additional, and Bunnell, Craig A., additional

Published
2017
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9. Getting Ready for Engineered Cell Therapies—an Administrative Perspective

Author

Emmert, Amy, primary, Winawer-Wetzel, Sarah, additional, Phicil, Shiela, additional, Lowery, Kurt, additional, Glotzbecker, Brett, additional, Nikiforow, Sarah, additional, Richard, Roger D., additional, Johnson, Kristen A., additional, Hennessy, Kerry Ann, additional, Shore, Melissa, additional, Rosenbloom, Stacy, additional, Huse, James, additional, Eramo, Anthony, additional, King, Bethany, additional, Sturtevant, Olive, additional, Savage, William J., additional, Alyea, Edwin P., additional, Soiffer, Robert J., additional, Bunnell, Craig Ann, additional, and Mersereau, Robert, additional

Published
2017
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10. A Systematic Approach to Providing Safe Quality Care for Patients Receiving Engineered, Non-Stem Cell Therapies

Author

Nikiforow, Sarah, primary, Winawer-Wetzel, Sarah, additional, Phicil, Sheila, additional, Lowery, Kurt, additional, Glotzbecker, Brett, additional, Clements, Marsha, additional, Mersereau, Robert, additional, Sturtevant, Olive, additional, Galinsky, Ilene, additional, Savage, William J, additional, Alyea, Edwin P., additional, Soiffer, Robert J., additional, Bunnell, Craig, additional, and Emmert, Amy, additional

Published
2016
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12. Age and the Risk of Paclitaxel‐Induced Neuropathy in Women with Early‐Stage Breast Cancer (Alliance A151411): Results from 1,881 Patients from Cancer and Leukemia Group B (CALGB) 40101.

Author

Barginear, Myra, Dueck, Amylou C., Allred, Jacob B., Bunnell, Craig, Cohen, Harvey J., Freedman, Rachel A., Hurria, Arti, Kimmick, Gretchen, Le‐Rademacher, Jennifer G., Lichtman, Stuart, Muss, Hyman B., Shulman, Lawrence N., Copur, M. Sitiki, Biggs, David, Ramaswamy, Bhuvaneswari, Lafky, Jacqueline M., and Jatoi, Aminah

Subjects
CANCER chemotherapy, LEUKEMIA, PERIPHERAL neuropathy, AGE distribution, AGE factors in disease, BREAST tumors, CANCER patients, DRUG side effects, LONGITUDINAL method, MULTIVARIATE analysis, PACLITAXEL, RISK assessment, STATISTICS, TUMOR classification, TUMOR grading, DISEASE risk factors
Abstract

Purpose: A few previous studies report a direct relationship between older age and chemotherapy‐induced neuropathy. This study further evaluated this adverse event's age‐based risk. Methods: CALGB 40101 investigated adjuvant paclitaxel (80 mg/m2 once per week or 175 mg/m2 every 2 weeks) in patients with breast cancer and served as a platform for the current study that investigated age‐based differences in neuropathy. Grade 2 or worse neuropathy, as per Common Terminology Criteria for Adverse Events version 4, was the primary endpoint; patients were assessed at baseline, every 6 months for 2 years, and then annually for 15 years. Results: Among these 1,881 patients, 230 were 65 years of age or older, 556 were 55–64 years, and 1,095 were younger than 55; 1,226 neuropathy events (commonly grade 1 or 2) were reported in 65% of the cohort. The number of grade 2 or worse events was 63 (27%), 155 (28%), and 266 (24%) within respective age groups (p =.14). In univariate analysis, only motor neuropathy had a higher age‐based incidence: 19 (8%), 43 (8%), and 60 (5%), respectively (p =.04); in multivariate analyses, this association was no longer statistically significant. Other endpoints, such as time to onset of neuropathy (time from trial enrollment to neuropathy development) and time to improvement (time from maximal grade sensory neuropathy to a one‐category improvement), showed no statistically significant age‐based differences. In contrast, obesity was associated with neuropathy, and every 2‐week paclitaxel was associated with trends toward neuropathy. Conclusion: Although paclitaxel‐induced neuropathy is common, older age is not an independent risk factor. Clinical trial identification number. NCT00041119 (CALGB 40101). Implications for Practice: Age alone is not an independent risk factor for paclitaxel‐induced neuropathy. Mixed results have been reported regarding whether older cancer patients are at a greater risk for chemotherapy‐induced neuropathy. This article further evaluates the age‐based risk of this adverse event. [ABSTRACT FROM AUTHOR]

Published
2019
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13. Impact of Genomic Assay Testing and Clinical Factors on Chemotherapy Use After Implementation of Standardized Testing Criteria.

Author

Natsuhara, Kelsey H., Losk, Katya, King, Tari A., Lin, Nancy U., Camuso, Kristen, Golshan, Mehra, Pochebit, Stephen, Brock, Jane E., Bunnell, Craig A., and Freedman, Rachel A.

Subjects
BREAST tumor diagnosis, CANCER relapse, BREAST tumors, CANCER chemotherapy, LONGITUDINAL method, MEDICAL records, MEDICAL practice, MULTIVARIATE analysis, TUMOR classification, GENETIC testing, MULTIPLE regression analysis, RETROSPECTIVE studies, EARLY detection of cancer, ODDS ratio, TUMOR grading, DIAGNOSIS
Abstract

Copyright of Oncologist is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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16. 113 - Getting Ready for Engineered Cell Therapies—an Administrative Perspective

Author

Emmert, Amy, Winawer-Wetzel, Sarah, Phicil, Shiela, Lowery, Kurt, Glotzbecker, Brett, Nikiforow, Sarah, Richard, Roger D., Johnson, Kristen A., Hennessy, Kerry Ann, Shore, Melissa, Rosenbloom, Stacy, Huse, James, Eramo, Anthony, King, Bethany, Sturtevant, Olive, Savage, William J., Alyea, Edwin P., III, Soiffer, Robert J., Bunnell, Craig Ann, and Mersereau, Robert

Published
2017
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18. Implementation of Surgeon-Initiated Gene Expression Profile Testing (Onco type DX) Among Patients With Early-Stage Breast Cancer to Reduce Delays in Chemotherapy Initiation.

Author

Losk K, Freedman RA, Lin NU, Golshan M, Pochebit SM, Lester SC, Natsuhara K, Camuso K, King TA, and Bunnell CA

Subjects
Adult, Breast Neoplasms epidemiology, Breast Neoplasms pathology, Drug Therapy, Female, Gene Expression Regulation, Neoplastic genetics, Humans, Middle Aged, Neoplasm Staging, Surgeons, Breast Neoplasms drug therapy, Breast Neoplasms genetics, Gene Expression Profiling
Abstract

Purpose: Delays to adjuvant chemotherapy initiation in breast cancer may adversely affect clinical outcomes and patient satisfaction. We previously identified an association between genomic testing (Onco type DX) and delayed chemotherapy initiation. We sought to reduce the interval between surgery and adjuvant chemotherapy initiation by developing standardized criteria and workflows for Onco type DX testing., Methods: Criteria for surgeon-initiated reflex Onco type DX testing, workflows for communication between surgeons and medical oncologists, and a streamlined process for receiving and processing Onco type DX requests in pathology were established by multidisciplinary consensus. Criteria for surgeon-initiated testing included patients ≤ 65 years old with T1cN0 (grade 2 or 3), T2N0 (grade 1 or 2), or T1/T2N1 (grade 1 or 2) breast cancer on final surgical pathology. Medical oncologists could elect to initiate Onco type testing for cases falling outside the criteria. We then examined 720 consecutive patients with breast cancer who underwent Onco type DX testing postoperatively between January 1, 2014 and November 28, 2016 and measured intervals between date of surgery, Onco type DX order date, result received date, and chemotherapy initiation date (if applicable) before and after intervention implementation., Results: The introduction of standardized criteria and workflows reduced time between surgery and Onco type DX ordering, and time from surgery to receipt of result, by 7.3 days ( P < .001) and 6.3 days ( P < .001), respectively. The mean number of days between surgery and initiation of chemotherapy was also reduced by 6.4 days ( P = .004)., Conclusion: Developing consensus on Onco type DX testing criteria and implementing streamlined workflows has led to clinically significant reductions in wait times to chemotherapy decision making and initiation.

Published
2017
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