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Urban areas contribute to nearly two-thirds of India's gross domestic product, but only constitute 31% of the country's population. In this paper, I address the following questions: What are the specializations of Indian cities and towns, and how have these changed over time; and what part of the specialization identified is a result of local advantages versus industry or national economic growth? Answers to these questions are basic to sustaining the competitiveness of India's cities. I used standard Census of India data at city level to compute location quotients for India's cities and towns, and examined changes in their economic base over time. Further, I performed shift-share analyses for selected large cities to disaggregate their employment growth. On average, over 1991-2001, specialization in all sectors, with the exception of trade, decreased. I found evidence of persistence in the sectoral specialization of Indian cities during 1991-2001. Further, in all non-agricultural economic sectors, cities in states know to be backward and lagging are specialized in most sectors. Based on location quotient analyses, I find that Mumbai is the financial capital of the country, Delhi is the seat of public administration, and Bengaluru specializes in transport, storage, and communications. [ABSTRACT FROM AUTHOR]