Based on monovinyl β-CD monomer (GCD), random copolymers (PTCDs) were first synthesized by AA, TPEG, and GCD, and characterized by FTIR and GPC. The application performances of PTCDs as superplasticizers in cement and concrete were investigated considering dispersion, adsorption, setting times, and compressive strength. The results indicated that PTCDs had more excellent applied performance compared with AA-co-GCD copolymers, and the outstanding feature is that PTCDs had a mild tunable retarding effect. When with certain amount of CD pendants and PEO side chains, PTCD2had the best dispersion and mild retarding performances, which were mainly attributed to the joint steric hindrance effect provided by CD pendants and PEO side chains. This study offers a new type of superplasticizer from CD and its derivatives with excellent dispersion and retarding performances to concrete engineering. [ABSTRACT FROM AUTHOR]