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One of the top issues in logistics management and related research is to establish an effective distribution system that is adaptive to new retail and capable of lowering the cost of logistics while enhancing consumer satisfaction. Aimed at reversing the weak points of current logistics distribution patterns, a dual-objective bipolar model with optimal logistics cost and consumer satisfaction by restraining distribution time and load is tested in this paper to figure out the proper nodes and vehicle routes. Data from general and front warehouses of PuPu mall, a Fuzhou-based online retail enterprise, are made into a case study. Moreover, the immune algorithm and genetic algorithm are adopted to achieve the model solution. It is found that the immune algorithm is more efficient than the genetic algorithm in searching solutions, thus having better adaptivity and effectiveness, and also that the type of distribution vehicle plays a significant role in determining the total distribution cost., Author(s): Dengqing Wang (corresponding author) [1,2]; Yuting Yang [2]; Yanhu Wang [3] 1. Introduction In recent years, online retail (also known as new retail) has shown a rapid growth trend. [...]