1. The people with Asperger Syndrome and anxiety disorders (PAsSA) Trial: A pilot multi-centre single blind randomised trial of group cognitive-behavioural therapy
- Author
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Louise Mullineaux, Edward C. F. Wilson, Aida Malovic, David Heavens, Lee Shepstone, David Fowler, Peter E. Langdon, Glynis H. Murphy, Alexandra Russell, Alice Rose, Wilson, Ed [0000-0002-8369-1577], and Apollo - University of Cambridge Repository
- Subjects
Paper ,050103 clinical psychology ,medicine.medical_specialty ,Population ,MEDLINE ,autism ,03 medical and health sciences ,0302 clinical medicine ,high functioning autism (HFA) ,Rating scale ,medicine ,0501 psychology and cognitive sciences ,Asperger syndrome (AS) ,Psychiatry ,education ,education.field_of_study ,05 social sciences ,Cognition ,anxiety ,medicine.disease ,Mental health ,030227 psychiatry ,cognitive behavioural therapy (CBT) ,Psychiatry and Mental health ,Asperger syndrome ,randomised control trial (RCT) ,Anxiety ,medicine.symptom ,BF41 ,Attribution ,Psychology - Abstract
BackgroundThere is a growing interest in using cognitive–behavioural therapy (CBT) with people who have Asperger syndrome and comorbid mental health problems.AimsTo examine whether modified group CBT for clinically significant anxiety in an Asperger syndrome population is feasible and likely to be efficacious.MethodUsing a randomised assessor-blind trial, 52 individuals with Asperger syndrome were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to treatment were followed up for 24 weeks.ResultsThe conversion rate for this trial was high (1.6:1), while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared with those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety.ConclusionsTrials of psychological therapies with this population are feasible. Larger definitive trials are now needed.
- Published
- 2016