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This book imparts a thorough understanding of the proper diagnosis, evaluation, and management of a patient with prostate cancer. The book provides guidelines for evaluation and investigation to reach a diagnosis with appropriate risk stratification of the disease, which is essential to evaluate the patient's survival and quality of life after the treatment. The book offers assistance, as per the patient and disease factors, appropriate treatment planning for an individual patient, and treatment outcomes for a better follow-up. This book aims to cover all aspects of prostate cancer with an additional supplement to the existing books in urology. This book targets postgraduates in urology, oncology, uro-oncology, practicing urologists, oncologists, and prostate cancer patients to know all aspects of the disease.

This book offers an authoritative and comprehensive overview of the wide range of surgical procedures and non-invasive options for the male cosmetic and reconstructive patients. Chapters examine the full gamut of unique male aesthetic and reconstructive surgical procedures, written by an interdisciplinary team of well-known and well-respected national and international contributors. The book provides an up-to-date and highly illustrated coverage of existing techniques and innovative, new technologies. Chapters relay the interplay between the unique male anatomy, expectations, clinical implications, therapeutic gems and approach to men seeking aesthetic enhancements. Each chapter highlights a concise but comprehensive description of the clinical issue augmented by appropriate illustrations, related art works, and videos. When applicable, an interdisciplinary style utilizing the expertise of allied specialties such as dermatology, facial plastic surgery, and oculoplastic surgery are utilized.Chapters address key issues and areas not previously included in other books, such as:Direct excision of nasolabial folds and submental regionFacial rejuvenation and other aesthetic procedure available to people of colorSurgery for body buildersBuried penisManagement of hyperhidrosisHIV: facial wasting and buffalo humpA Comprehensive Guide to Male Aesthetic and Reconstructive Surgery is a must-have resource for plastic and reconstructive surgeons to successfully manage the distinctive, unique needs of the male patient.

Comprehensive Hematology and Stem Cell Research is the first major reference to cover both stem cell research and therapy as well as the range of hematological disorders they are currently used to treat and may potentially be able to treat in the future. This five volume set includes fundamentals, such as the underlying mechanisms of the blood and immune system, highlighting blood disorders and cancers of the blood, including lymphoma, leukemia, and myeloma. Other sections cover stem cell research and therapy, from harvesting stem cells to their utilization in cancer treatments. Finally, the work looks to the future and explores newer stem cell research that may lead to future treatments. This book is an excellent resource for students at the graduate and post-graduate levels, academics, and researchers in the fields hematology, immunology and oncology. - Compiles foundational knowledge and breakthrough research into one concise, comprehensive reference - Takes a translational, bench-to-bedside approach to hematological disorders and stem cell therapies - Covers clinical applications of stem cells, advances in the field, and promising new research

Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases, among other disease types. Step-by-step instruction is provided around research protocols and methods discussed, along with careful attention to the ethical implications of mitochondrial transplantation research and application. - Provides an in-depth discussion of mitochondrial transplantation, considering fundamental biology, disease implications, research methods and applications - Discusses recent advances in the field and their meaning for future research and clinical utility - Considers ethical dimensions of mitochondrial transplantation research and use in therapeutics - Examines mitochondrial transplantation across a range of disease types, from neurological to cardiovascular disease and ischemia

This book introduces neurourology as an emerging interdisciplinary area that covers the basic and clinical studies of the neural control on the normal lower urinary tract and the lower/upper urinary tract dysfunction due to neuropathy disorders. It systematically describes all aspects of neurourology from the epidemiology of the neurogenic bladder; to the pathology and pathophysiology of the lower urinary tract; to the diagnosis and treatment of the neurogenic bladder by conservative therapies or surgeries. This book provides a useful resource for medical doctors, nurses and students in the field of neurourological conditions.In this 2nd edition, 15 chapters are added, e.g. on urodynamic practice, psychogenic reasons of LUTDs, standard of care, physiotherapy, upper urinary tract rehabilitation to enable self-catheterization, pediatric neurourology, new surgical procedures. The editors have invited an impressive number of renowned contributors, including 98 internationally recognized specialists in this field from 25 countries in Europe, Asia, North America, and South America. This handbook provides a useful resource for medical doctors, nurses and students in the field of neurourological conditions.

Reduced Order Models for the Biomechanics of Living Organs, a new volume in the Biomechanics of Living Organisms series, provides a comprehensive overview of the state-of-the-art in biomechanical computations using reduced order models, along with a deeper understanding of the associated reduction algorithms that will face students, researchers, clinicians and industrial partners in the future. The book gathers perspectives from key opinion scientists who describe and detail their approaches, methodologies and findings. It is the first to synthesize complementary advances in Biomechanical modelling of living organs using reduced order techniques in the design of medical devices and clinical interventions, including surgical procedures. This book provides an opportunity for students, researchers, clinicians and engineers to study the main topics related to biomechanics and reduced models in a single reference, with this volume summarizing all biomechanical aspects of each living organ in one comprehensive reference. - Introduces the fundamental aspects of reduced order models - Presents the main computational studies in the field of solid and fluid biomechanical modeling of living organs - Explores the use of reduced order models in the fields of biomechanical electrophysiology, tissue growth and prosthetic designs

This book provides a comprehensive guide to the latest techniques in female genitourinary and pelvic floor disorders. It features detailed insight into these conditions along with detailed descriptions of how treatment has changed in recent times for these disorders. The latest methodologies for pharmacological treatment, conservative therapy, surgical techniques, and how to avoid potential complications are discussed. Topics including relevant neurophysiology, measurement of urinary symptoms, pelvic organ prolapse and ureteral reconstruction are covered. Female Genitourinary and Pelvic Floor Reconstruction is a detailed resource detailing the latest developments in the field, making it an ideal resource for all clinicians who encounter these patients in their daily practice.

This open access book offers a valuable resource for understanding the correct pathways in the context of sexual disorders, couple reproduction, gender identity dysphoria, conditions for which patients commonly ask for consultation and treatment. Based on clinical evidence, international guidelines and experts experience, practical clinical management strategies are presented for each condition. Each clinical care pathway is based on updated algorithm, level of evidence, photos and video-clips that describes the clinical presentations and the best practice management through diagnostic tools and medical or surgical treatment. Leading experts from the most important center of excellence in the field of sexual medicine joined to cover the field of andrology in its entirety, each of them dealing with a single topic from the top of their recognized experience and providing a complete and update textbook that will help urologists and other physicians in their daily clinical practice. This book is thought to be a practical and valuable reference for urologists, gynecologists, endocrinologists, psychiatrics and psychologists, and residents who are not specialty trained in andrology. It is designed for both young fellows training in different specialties and coming into contact with andrological issues for the first time and also more experienced clinicians and surgeons requiring updated guidelines and clear advice on the most controversial issues. This book will represent an invaluable quick consulting tool, updated in its scientific contents and rich in tables, images and video-clips.

This book is focused on a clinical-based diagnostic approach of autonomic dysfunctions, highlighting main diagnostic tools and pharmacological and non-pharmacological therapies available nowadays. The autonomic nervous system (ANS) is a subcomponent of the peripheral nervous system (PNS) and dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability. A myriad of factors can cause autonomic dysfunction and more than one can concur even in the same patient; due to the expansive nature of the ANS, patients can be affected by a wide range of conditions. Each chapter is characterized by a similar structure and is devoted to a different dysfunction. For each pathology, the book offers the essential information on mechanisms of action, treatments and outcomes. Written by experts in the research of these disorders, the volume addresses primarily Neurologists, but will be a useful tool also for Gastroenterologists, Ophthalmologists, Urologists, Cardiologists and Internal medicine specialists.

This book provides comprehensive information to all medical doctors regarding novel angiogenic and bioengineering medical treatments. Tissue healing is significantly hampered by ineffective neovascularization at the site of the defect, resulting in poor clinical outcomes. The fabrication of biomaterial-based scaffolds with adequate vascularizing abilities is the prevailing challenge that has drawn considerable attention from the scientific community. The decisive roles of vascularized biomaterials as bone and skin substitutes, and in various soft and hard tissue engineering, have been investigated widely. Cell-based and scaffold encapsulating bioactive molecules-based approaches are essential means of developing efficient angiogenesis in tissue defects. To fulfill the necessity of an optimum long-term vascularizing scaffold, it should essentially be economic, controlled, and reproducible. While a lot has been achieved towards acknowledging newer molecules with vascularizing abilities; there is a broad gap wherein we need to develop in vitro vascularized implants as well as tissues and organs with the advanced technologies and knowledge at our disposal.

La médecine sexuelle et la sexologie sont devenues aujourd'hui une vaste et riche discipline qui couvre différents champs de connaissances et de pratiques. Celles-ci ont grandement évolué ces dernières années : nouvelles connaissances sur l'anatomie, évolution des diagnostics cliniques des troubles sexuels, meilleure prise en compte des questions de diversité sexuelle et de genre, programmes mieux adaptés à certaines populations (personnes âgées, malades…) Cette nouvelle édition de Médecine sexuelle, Fondements et pratiques augmentée et réorganisée, est divisée en sept grandes parties portant sur : les fondements anatomophysiologiques et les troubles sexuels masculins et féminins ; les troubles psychosexuels et la sexologie médicolégale ; les populations particulières et leur sexualité ; les chirurgies sexuelles et enfin, les interventions sexothérapeutiques. Ouvrage de référence dans le milieu francophone, à la fois clinique et académique, il s'appuie sur une documentation scientifique de la médecine basée sur les preuves (evidence based medicine), et offre aussi bien une revue des fondements utiles à la pratique sexologique, que des bases diagnostiques, médicales, sexothérapeutiques et chirurgicales de la pratique clinique.

Andrology & Sexual Medicine is a comprehensive source for urologists, andrologists, sexologists and general practitioners. It contains general and up-to-date information about almost all topics within andrology and sexual medicine, and is a unique source that can be used for both exams and general daily practice. Easily accessible to clinicians and researchers and specialists, it tackles the controversial and complex topics of andrology and sexual medicine for urologists.

Featuring contributions by an international team of the world's experts in urology and gynecology, this fifth edition reinforces its status as the classic comprehensive resource on female urology and urogynecology and an essential clinical reference in the field. There are new chapters throughout and new commentaries on important documents in the appendixes; each volume is now available separately. •Offers a comprehensive guide to surgical aspects •Covers important and common topics such as pelvic organ prolapse and robotic surgery and newer topics such as transgender surgery •Presents a practical and manageable level of detail

This contributed volume gathers the latest knowledge in the field of stem cells in human reproductive organs, as well as animal models, and to consider the possibility of using this knowledge for clinical purposes. The scope of the book covers both clinical and basic knowledge of stem cells in both reproductive medicine (gynecology and obstetrics) and regenerative medicine as well as cellular and molecular medicine and reproductive biology. Chapters on basic stem cell knowledge in human reproductive tissues and organs or animal models are included, as well as clinical knowledge on their role in the manifestation of infertility and cancer and their clinical use.

This book comprehensively covers the techniques available for robot- assisted prostatectomy. Chapters feature detailed descriptions of how to successfully perform a variety of relevant techniques including the reconstruction of continence mechanisms and the use of the transperitoneal RALP anterior approach. Potential complications, preoperative and postoperative management strategies are also discussed, enabling the reader to develop a thorough understanding of how to apply a range of relevant methodologies into their day-to-day clinical practice and avoid commonly encountered pitfalls.Robot-Assisted Radical Prostatectomy: Advanced Surgical Techniques provides a practically applicable resource for all practicing and trainee urologists seeking a detailed overview of the latest advances in robot-assisted surgical procedures and current management strategies applicable to prostatectomy.

This book provides a comprehensive review of the etiology, anatomy, diagnosis, treatments, and future directions of care for female incontinence. It includes a historical review of past treatments many women have undergone and resultant altered anatomy. This book discusses conservative treatments such as patient and provider handouts on behavioral modification and how to perform pelvic floor exercises. It also covers medical therapy from minimally invasive treatments to radical surgical approaches and management of treatment failures. Addressing the treatment of stress incontinence with chapters progressing from least invasive to most invasive therapies, it also describes mesh complications and treatment failures. The book illuminates the intersection of prolapse with female incontinence, incontinence diagnosis and management after major reconstructions such as neobladder or penile inversion, vaginoplasty, and incontinence due to rarer conditions such as fistulas. Further chapters explore female urinary incontinence in special populations including pediatric patients, the elderly, and women with neurogenic lower urinary tract dysfunction, as well as poorly understood populations such as older children, women post-reconstruction, and trans-women. It also addresses research needs and the ever-expanding horizon of new developments in the field of incontinence in women. Female Urinary Incontinence provides a comprehensive text directed towards urologists, gynecologists, and those trained in female pelvic medicine and reconstructive surgery (FPMRS). Given the topic of incontinence specifically in women and the burgeoning rise of women in the field of FPMRS, the book features an all-female author list comprised of an international group of female urologists and urogynecologists selected to author chapters on their particular expertise.

Scientific Advances in Reconstructive Urology and Tissue Engineering is a comprehensive overview of reconstructive urology that spans male and female, pediatric, neuro-urology and trauma. Traditionally, this field has been focused solely on surgical principles with little attention to basic and translational research. However, recent advances in acellular matrices, scaffolds, stem cells and tissue engineering have changed this focus. This publication is the perfect bridge and definitive tome of the advances that will move the translational and basic science of reconstructive urology forward and allow readers to implement the findings in clinical practice. Through the use of both current case studies and future implications, the content bridges the gap from bench to bedside making it the perfect reference for translational benign urology researchers who wish to move the field of reconstructive surgery forward. - Includes real-world applications of current research to help readers get rapidly up-to-speed on which research results are appropriate for immediate implementation - Presents the underlying mechanism of urologic disease processes pertinent to reconstructive urology for comprehensive understanding within the field - Provides independent guidance to manage specific clinical conditions while also presenting approaches that are applicable to all conditions

Sexual Dysfunction in Parkinson's Disease, Volume 182, the latest release in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of trending and important topics, including Prevalence, clinical presentations and impact on relationship, Pathophysiology, Scales for assessing sexual dysfunction in Parkinson's disease, Diagnostic work up: Laboratory and biomarkers, Management strategies, ICD DDS and sex dysfunction, Non-motor fluctuations and sex dysfunction, Exploring Sexual Dysfunction in Care Homes, and The impact of non-motor symptoms burden on sexual functions. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the International Review of Neurobiology series - Updated release includes the latest information regarding Sexual Dysfunction in Parkinson's Disease

This book provides a detailed overview of a range of simulation models that have been developed which are applicable to urology. Chapters feature critical analysis of techniques including synthetic bench top models, computer-assisted virtual reality and box simulators. Furthermore, details of best practice, the latest innovations and guidance on how to select potential low-cost options is provided, enabling the reader to systematically develop a thorough understanding of the subject.Practical Simulation in Urology is a comprehensive resource that critically analyses the latest simulation techniques that are applicable in urology, making it an ideal resource for the practicing and trainee urologist seeking an up-to-date overview on the subject.

This book covers sensation in all major components of the pelvic region. The small pelvis is containing many different structures and viscera, and sensations elicited there are important for regulating a normal daily life and for warning that something is going wrong. The sensory system is driving in many aspects the motor activity, and precedes and guides the efferent functions. It is surprising that in the last 60 years the ratio between research and publications about sensory versus motor has gradually become less. There has been undoubtedly a rise in the number of publications written on pelvic sensation but in the same time the number of manuscripts on motor function have increased more.It is the hope that this compilation of most data available on sensation will be of interest for the reader, will incite to perform more research so that an important part of pelvic functional diagnosis and treatment modalities will use the whole of the mechanisms available.Thebook is intended for all interested in pelvic functions and the interactions between the different structures, specialists in urology, gastroenterology, sexuality, pain, pelvic floor function and dysfunction, paediatricians and geriatricians, neurologists, students and those in training. The reader will find interesting and challenging information, and suggestions for further research.

The standard-setting text in oncology for 40 years, DeVita, Hellman and Rosenberg's Cancer: Principles and Practice of Oncology, 12th Edition, provides authoritative guidance and strategies for managing every type of cancer by stage and presentation. Drs. Vincent T. DeVita, Jr., Theodore S. Lawrence, and Steven A. Rosenberg oversee an outstanding team of expert contributing authors who keep you up to date and fully informed in this fast-changing field. This award-winning reference is also continually updated on Health Library and VitalSource platforms for the life of the edition.

A unique textbook in laparoscopic surgery which deals with all essential aspects for surgeons, gynecologists, and urologists. Specifically address topics of fundamentals of laparoscopic surgery and operative steps of each procedure in detail. Aimed not only at the dedicated laparoscopic surgeons, but also at general surgeons, gynecologists, urologists, and surgical trainees. Aim of each chapter is to define, sharpen and emphasize issues of surgical steps, using the available evidence. Art and science of minimal access surgery is explained giving a true overall view as well as the recent technological advances made in this field. Intended for those who are conversant with operative surgical and gynecological procedures. Its scope is broad and deep. Illustrations and diagrams are provided to facilitate faster learning of minimal access surgery. Self-sufficient book which explains the concept of ergonomics, task analysis and practical, and practical problems encountered in laparoscopic operative surgery. An overall view of the latest instruments and techniques of their application is presented.

This updated book is a practical guide to intrapartum ultrasonography to help practitioners improve labor and delivery, and to limit, where possible, complications. Presenting the authors'experiences, the book summarizes the state of the art in normal and abnormal labor. It clearly documents the use of intrapartum ultrasonography to evaluate the first and second stages of labor and diagnose the occiput posterior and transverse positions. Each situation is analyzed with the help of numerous informative images and invaluable tips and tricks showing how fetal head engagement and progression can be documented objectively. The importance of ultrasound in obstetrics risk management is also addressed. Explaining how intrapartum ultrasonography can be used to assess whether a safe natural delivery is likely or whether operative procedures are required, the book is a valuable resource for all professionals – physicians and midwifes alike – caring for women in labor.

This book summarises the entire field of adult neuro-urology in a concise, well-illustrated, and practical style. Contents include epidemiology, lower urinary tract anatomy and physiology. This is followed by coverage of the pathophysiology of various types of voiding dysfunctions and a clinical section focusing on practical evaluation and treatment. A range of treatments from behavioral, pharmacological, intra vesical, tissue engineering and surgical are explained and reviewed. Other topics such as complications, sexual function, fertility, maternity aspects, and prognostic factors round off the book. •Each topic is covered in detail and well illustrated. •The reader will gain a full understanding of every aspect of adult neuro-urology. •Facilitates improved clinical knowledge and practice.Provides an essential and complete reference tool for students and established urologists, neurologists, physiotherapists and nurses, and technicians involved in the care of patients with neurogenic bladder dysfunction.

Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.

Orientation of Prehistoric Monuments in Britain: A Reassessment views the type of major axial alignment seen at many megalithic ritual and funerary monuments of Neolithic to Bronze Age date in Britain and Ireland, not in terms of more abstract astronomical concerns, but rather as an expression of repeated seasonal propitiation, basically solar, involving community, agrarian economy, and the ancestors in a combined attempt to mitigate variable environmental conditions. The analysis is supported by over 800 images, open-source, for unrestricted use, and available digitally.

This book outlines the approach to comprehensive men's health deployed at three of the most successful American men's health centers. It demonstrates the ways in which multidisciplinary care allows patients to easily access their doctors via coordination of care, same day add-on visits, and streamlining of office logistics such as sharing of charts, reports, and results. Guiding readers in establishing an evidence-based, multidisciplinary approach to the management of male patients of all ages, this volume shows how prevention, rapid intervention, cost efficiency, and coordinated care are at the forefront of a health center's care strategy. The authors of this volume are thought leaders in the disciplines of cardiology, gastroenterology, dermatology, psychiatry, and preventative medicine.Design and Implementation of the Modern Men's Health Center: A Multidisciplinary Approach enables urologists, medical subspecialists, and surgical subspecialists to both manage basic patient issues and also to understand how multidisciplinary care enables the success of a men's health center.

Glaciers and Polar regions provide important clues to understanding the past and present status of the Earth system, as well as to predict future forms of our planet. In particular, Antarctica, composed of an ice-covered continent in its center and the surrounding Sothern Ocean, has been gradually investigated during the last half century by all kinds of scientific branches; bioscience, physical sciences, geoscience, oceanography, environmental studies, together with technological components. This book covers topics on the recent development of all kinds of scientific research on glaciers and Antarctica, in the context of currently on-going processes in the extreme environment in polar regions.

The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

This book focuses on bladder cancer pathology, including primary bladder malignancies and other tumor varieties, with an emphasis on diagnostic pitfalls and clinical relevance. It also describes normal bladder histology, benign abnormalities with cancer mimickers, and cancer carcinogenesis, which are important subject matter for understanding bladder cancers, correct diagnosis, and differential diagnoses. Accurate diagnosis of bladder cancer plays a central role in daily pathology practice, clinical management, and prognosis. Advances in immunohistochemistry and molecular pathology have enhanced the accuracy of cancer pathology diagnoses. In addition to covering the anatomic and histologic features of bladder tumors, this book also reviews recent molecular and immunohistochemical advances in these areas. Recently updated clinical management information is also presented in this book.Written by experts in the field, Urinary Bladder Pathology serves as a useful resource for practicing pathologists, pathology trainees, and other health professionals who treat patients with bladder cancers.

Tissue Engineering Using Ceramics and Polymers, Third Edition is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction, repair and organ regeneration. With its distinguished editors and international team of contributors, this book reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. New sections cover nanobiomaterials, drug delivery, advanced imaging and MRI for tissue engineering, and characterization of vascularized scaffolds. Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated with the aid of biomaterials. - Provides updated and new information on ceramic and polymer biomaterials for tissue engineering - Presents readers with systematic coverage of the processing, characterization and modeling of each material - Includes content that will be relevant to a range of readers, including biomedical engineers, materials scientists, and those interested in regenerative medicine

A comprehensive reference for the diagnosis and treatment of female sexual pain disorders Female Sexual Pain Disorders: Evaluation and Management, 2nd Edition compiles the most cutting-edge and modern research on sexual pain disorders in women into a single reference. It is the first book of its kind devoted to the diagnosis and treatment of sexual pain in women and is now fully updated in a second edition. The book includes diagnostic tools to differentiate among different forms of dyspareunia, discussions of potential causes of sexual pain, and current knowledge in multi-disciplinary treatments for dyspareunia. Focused on providing practical guidance to the working practitioner, this book includes information to: Help evaluate and distinguish the causes of sexual pain in women&nbsp Assist in the differentiation of the many forms of sexual pain Implement multi-disciplinary treatments Female Sexual Pain Disorders is perfect for any healthcare worker who is involved in treating women's sexual health, including gynecologists, urologists, internists, family practitioners, nurse practitioners, physician assistants, midwives, psychologists, and sex therapists.

This is the tenth edition of this Fast Facts handbook since the first was published in 1996 – the many iterations are testament to the rapid changes in the field and steadily improving outlook for patients. This new edition introduces the Gleason grade grouping (Chapter 1), which has important prognostic value, and nomograms that are used to evaluate risk (Chapter 3). Our understanding of the genetics and underlying pathogenesis of prostate cancer is growing apace, leading to the identification of germline mutations and the development of genomic tests to help identify and direct therapy for those at greatest risk of developing clinically significant disease. They also provide reassurance for those patients who have opted for active surveillance (Chapters 3 and 5). Imaging techniques are also improving rapidly, particularly multiparametric MRI (Chapter 4). As this book is concise, fully up to date and evidence based, we believe it is an ideal resource for those general urologists, primary care providers, specialist nurses, trainees and allied healthcare professionals who want to get quickly up to speed in this fast-moving and ever-expanding field. Contents: • Epidemiology and pathophysiology • Diet, lifestyle and chemoprevention • Screening and early detection • Diagnosis, staging and prognostic indicators • Management of clinically localized disease • Managing recurrence after initial therapy • Managing metastatic hormone-sensitive prostate cancer • Management of castrate-resistant prostate cancer • Survivorship and management of treatment-related side effects and complications

This book focuses on recent advances in obstetrics & gynaecology 27. The translation of scientific discovery into clinical practice continues to advance at speed across the diverse range of subspecialties in obstetrics and gynaecology. The purpose of this book is to non-specialists to be updated in some of the most rapidly advancing areas. This book consists of 9 chapters, which include fetal therapy and surgery, the impacted head at caesarean section, midwifery-led care for women at all levels of risk, the role of urodynamics in female lower, medical management of urinary incontinence in the premenopausal woman, caesarean scar ectopic pregnancy, ambulatory interventions in the management of acute gynaecology and early pregnancy complications, hereditary cancer in gynaecology, and vulval cancer in elderly women. The 27th in the series of Recent Advances in Obstetrics and Gynaecology maintains the high standards set over many years. It is entertaining to read through the earlier volumes in the series as they reflect changes in thinking and practice over many years. This book is an invaluable update and revision tool for trainees preparing for postgraduate examinations.

The field of anatomy is dynamic and fertile. The rapid advances in technology in the past few years have produced exciting opportunities in the teaching of gross anatomy such as 3D printing, virtual reality, augmented reality, digital anatomy models, portable ultrasound, and more. Pedagogical innovations such as gamification and the flipped classroom, among others, have also been developed and implemented. As a result, preparing anatomy teachers in the use of these new teaching tools and methods is very timely. The main aim of the second edition of Teaching Anatomy – A Practical Guide is to offer gross anatomy teachers the most up-to-date advice and guidance for anatomy teaching, utilizing pedagogical and technological innovations at the forefront of anatomy education in the five years since the publication of the first edition. This edition is structured according to the teaching and learning situations that gross anatomy teachers will findthemselves in: large group setting, small group setting, gross anatomy laboratory, writing examination questions, designing anatomy curriculum, using anatomy teaching tools, or building up their scholarship of teaching and learning. Fully revised and updated, including fifteen new chapters discussing the latest advances, this second edition is an excellent resource for all instructors in gross anatomy.

This text provides a comprehensive and multidisciplinary, state-of-the-art review of complications related to surgical procedures for male urinary and fecal incontinence. As surgery has evolved over the decades, newer and at times unexpected intraoperative and long-term complications have arisen. Specialists who are unfamiliar with them need to know how to manage these specific complications and, more importantly, how to avoid them in the course of their future practice. This volume provides an essential guide for all urologists, proctologists and surgeons operating on male patients with urinary and fecal incontinence.

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more.

This book provides a comprehensive overview of percutaneous nephrolithotomy, covering topics including its history, anatomy, preoperative preparation, clinical operation, and postoperative treatment. It presents both basic and advanced techniques, such as micro-PNL, mini-PNL, ultra-mini-PNL, and super mini-PNL, together with representative clinical cases. In addition, the book describes potential technical issues, complications, indications and contraindications in detail, making it a valuable reference guide for urologists, especially those who wish to improve their PCNL skills in clinical practice.

As the world's population ages, the problem of degenerative disease is increasing. At the same time, the demand for organ transplants to repair or replace damaged tissue continues to grow. Regenerative medicine is a branch of translational medicine which promotes the repair, regeneration, or construction of tissues and organs or improves or restores their function through tissue engineering, cell biology, molecular biology and other techniques. Stem cells are one of the most important types of cells used in regenerative medicine, and stem cell research is also one of the most active research areas in the field. This book presents 20 full papers from the 8th International Symposium China-Europe “Stem Cells and Regenerative Medicine”, held in Wuhan, China from 19-21 June 2018. At this symposium, researchers in the field of stem cells and regenerative medicine from China and France discussed research from a molecular point of view and pointed out the clinical applications of mesenchymal stem cells, as well as the construction and applications of new biomaterials, the biomechanics of bone tissue engineering, and cellular immunotherapy, among other subjects. Stem cell technology could soon make possible the repair or replacement of aging and damaged tissue, as well as providing a treatment for genetic defects and malignancies,and this book will be of value to all those with an interest in regenerative medicine.

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions.This book series'Cell Biology and Translational Medicine (CBTMED)'as part of SpringerNature's longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the fourth volume of a continuing series.

This book provides a comprehensive overview of contemporary evidence-based management of urothelial carcinoma. The first part of the book is devoted to urothelial carcinoma of the bladder and includes detailed description of the diagnosis and treatment of non-muscle-invasive, muscle-invasive, and advanced or metastatic disease. Attention then turns to upper tract urothelial carcinoma (UTUC), with individual chapters on diagnosis, nephron-sparing surgery, nephroureterectomy, and treatment of advanced or metastatic UTUC. The text is supported by many illustrations, photos, and tables that clarify management, and surgical video clips are also available to readers. The book will be a welcome addition to the literature as progress continues to be made in understanding the exact pathophysiology of urothelial carcinoma and in developing more effective diagnostic and therapeutic modalities. It will be useful both to researchers in the field of urothelial carcinoma and to clinicians, includingespecially residents and fellows.

This book is a comprehensive and current guide to the diagnosis and treatment of the entire spectrum of anorectal diseases. It focuses mainly on anorectal problems, as anorectal pathology is often more complex and challenging for surgeons than colonic diseases.The book covers anorectal anatomy, physiology, and embryology as a foundation to a detailed description of preoperative, intraoperative, and post-operative patient management. All surgical procedures are shown in step-by-step detail by leading surgeons and gastroenterologists. This book will be relevant to general, colon, and rectal surgeons in training and practice, gastroenterologists, and other practitioners with an interest in anorectal diseases.

This book provides an in-depth insight into the symptoms and symptom complexes affecting the lower urinary tract and the underlying causative conditions. The emphasis throughout is practical and clinical, with coverage of all levels of the patient pathway. In addition to the extensive guidance on diagnostic assessment and interpretation, the management of voiding and storage lower urinary tract symptoms, including incontinence, is fully described and potential complications and neurological conditions are discussed. Information is also included on relevant basic science and epidemiology. Lower Urinary Tract Symptoms in Adults: A Clinical Approach will be an ideal source of expert knowledge for practitioners in functional urology, urogynecology, and neuro-urology gerontology..

This book introduce neurourology as an emerging interdisciplinary area that covers the basic and clinical studies of the neural control on the normal lower urinary tract and the lower/upper urinary tract dysfunction due to neuropathy disorders. It systematically describes all aspects of neurourology from the epidemiology of the neurogenic bladder; to the pathology and pathophysiology of the lower urinary tract; to the diagnosis and treatment of the neurogenic bladder by conservative therapies or surgeries. This book provides a useful resource for medical doctors, nurses and students in the field of neurourological conditions. All the topics are written by internationally recognized specialists in their field.

The 29th European Symposium on Computer Aided Process Engineering, contains the papers presented at the 29th European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Eindhoven, The Netherlands, from June 16-19, 2019. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries. - Presents findings and discussions from the 29th European Symposium of Computer Aided Process Engineering (ESCAPE) event

Der vorliegende Band „Knochenmark, Lymphatisches System, Milz, Thymus“ ist mehr als 30 Jahre nach Erscheinen der 1. Auflage inhaltlich und strukturell völlig neu gestaltet worden. Er enthält nicht nur die diagnostische Hämatopathologie der anatomischen Bildungs- und Reaktionsorte des hämopoietischen und lymphatischen Systems, sondern berücksichtigt auch alle Organe mit speziellen hämatopathologischen Erkrankungen wie beispielsweise die Lymphome in den Geweben des Mukosa-assoziierten Immunsystems. Eine Betonung erfährt auch die Darstellung organübergreifender gemeinsamer ätiologischer Faktoren, z.B. der Infektionen. Schließlich werden beim Thymus auch alle epithelialen Tumoren und nichtlymphatischen Erkrankungen diskutiert. Dieses Buch richtet sich an Pathologen und Kliniker mit dem Versuch, die diagnostischen Grundlagen eines zielgerichteten therapeutischen Vorgehens für die reale Situation des Einzelpatienten zu definieren. Die Herausgeber hoffen, dass dervorliegende Band diesem Anspruch gerecht wird.

The only practical resource to focus solely on health issues specific to menWritten by and for APRNs and PAs in the primary care setting, this is the first clinical reference to focus solely on managing health concerns that are specific to men. Filling a significant gap in knowledge about this patient group, the user-friendly reference delivers evidence-based guidelines for the day-to-day management of male patients.Designed for ease of use and quick access to information, the resource is divided into three sections: general men's health, overview of special issues in men's health, and urology and preventive cardiology. In addition to addressing the full gamut of urological and cardiac issues, the book discusses the basics of male physical assessment including sports assessment, male adolescent risk issues, musculoskeletal manifestations of stress in men, and health screening issues. Also covered are the aging male and physical activity, the health needs of male veterans, complementary and alternative health methods, chronic pain, high-risk MSM sexual health issues, and starting a men's health clinic.Key Features:The only practical men's health resource written specifically for APRNs and PAs by APRNs and PAsOrganized to facilitate quick access to informationDelivers evidence-based guidelines for men's healthcareWritten and edited by noted APRN and PA men's health practitioners and facultyAddresses health issues in urology, cardiology treatment for men, and other health issues specific to men

The sixth edition of The Kelalis-King-Belman Textbook of Clinical Pediatric Urology presents state-of-the-art knowledge and common-sense practice in all areas of clinical pediatric urology in a single, easily accessible volume. Clinical in orientation and practical in presentation, it covers every disorder and disease, diagnostic method, and appropriate treatment in pediatric urology from the embryo onwards. Widely acknowledged as the leading reference in the field, the book is essential reading for all practitioners who deal with urological disorders of childhood, whether trainees, residents or experienced specialists. The book begins with chapters on evaluating the patient and general principles of pediatric urology, including the use of advanced diagnostic imaging techniques and the increasing importance of minimally invasive surgical techniques. It then proceeds through the entire urinary tract from adrenal gland to external genitalia, discussing anatomy, normal and abnormal development, anomalies and diseases and their treatment.

Encyclopedia of Cancer, Third Edition, Three Volume Set provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health, all set alongside the latest advances and hot topics that have emerged since the previous edition. Topics of interest in the field, including genomics and epigenomics, our understanding of the causes of cancer and the approaches to preventing it (e.g., HPV vaccination, role of obesity and nutrition, molecular markers of environmental exposures), new screening techniques (e.g., low-dose CT for lung cancer) and improvements in the treatment of many cancers (e.g., breast cancer, lung adenocarcinoma) are comprehensively and authoritatively presented. - Comprises 180 contributions from renowned experts who present the latest in mechanisms, hallmarks of cancer, causes, prevention and control, diagnosis and therapy, pathology and genetics - Presents a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health

This fourth edition of Surgery of the Anus, Rectum and Colon continues to redefine the field, with its comprehensive coverage of common and rare colorectal conditions, advances in the molecular biology and genetics of colorectal diseases, and new laparoscopic techniques. Contributions from international experts on specialized topics and various new illustrations ensure that the extensive text is not only current and authoritative, but easy to understand. No other book provides the expertise of a world-class editorial team with the cutting-edge knowledge you need to master colorectal surgery.