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Titan After Cassini-Huygens is the most up-to-date and comprehensive coverage of our knowledge on Titan, including results and insights from the joint NASA/European Space Agency/Italian Space Agency mission Cassini-Huygens and the conclusions drawn by experts following detailed analysis of the mission data. Our knowledge of Titan has increased substantially due to observations from the Cassini-Huygens mission, which ended in 2017. Since then, observations from Earth, as well as laboratory and theoretical studies, have continued to add to our knowledge. These conclusions, combined with the latest ground-based and theoretical research, provide the most recent understanding of the science of Titan, covering the origin and evolution of Titan, its magnetic and plasma environment, surface, interior structure, geology, atmosphere, and the astrobiological potential for the oceans on the moon.The first book of the new COSPAR book series, Titan After Cassini-Huygens, is an integral reference for scientists, researchers, and academics working on Titan or ocean worlds. Part of the COSPAR Book SeriesEdited by Jean-Louis Fellous, former Executive Director of COSPAR (Committee on Space Research; 2008–2019) - Details the total knowledge of Titan from Cassini-Huygens and subsequent observations from Earth, as well as laboratory and theoretical studies from the last decade - Covers all aspects of Titan, including origin and evolution, magnetic and plasma environment, surface, interior structure, geology, atmospheric science and astrobiological potential - Provides detailed, referenceable data from investigators of the Cassini spacecraft and Huygens probe, as well as the ALMA radio telescope observatory

This new book, Plant Diseases and Their Management: A Sustainable Approach, studies the most modern methods in control and management of plant diseases. It covers a wide range of themes on the biological, cultural, chemical, and genome engineering controls for plant diseases brought on by viruses, bacteria, phytoplasma, and fungi.This book details how natural materials, organic disease control, and new-generation fungicides can all be utilized to thwart or stop plant pathogen activity in an effective manner. The book also delves into methods for increasing the shelf life of produce, presents approaches to plant disease management in organic as well as conventional farming, and considers molecular approaches to disease detection and identification in plants.The book looks at viral, bacterial, and fungal diseases in different plants and their management. It also discusses several pathogens and how diseases caused by these can be managed effectively. It also covers diseases in specific crops, such as rice, pulses, fruits, and vegetables, including apples, berries, and capsicum. A novel approach of genome engineering to develop resilience in plants against various diseases and future challenges is considered as well.Key features: Presents management approaches to fungal, phytoplasmal, viral, and bacterial plant diseases Discusses the protection of fruits, vegetables, and crops from various diseases for prolonged shelf-life Looks at genome engineering as a novel approach for fungal, bacterial, and viral disease management Considers both traditional and modern methods in the management of viruses infecting plants Covering new methods for the sustainable control of plant diseases, this volume will be valuable to plant and crop specialists, agriculture-based industries, and faculty and students in the agricultural sciences.

Understanding the complex interplay between food safety, nutrition, bioscience, and data algorithms is crucial for effectively managing autoimmune diseases. However, the current literature often needs a comprehensive resource that integrates these disciplines, leaving researchers, clinicians, and industry professionals needing a clearer understanding of how to apply these concepts in practice. This gap in knowledge hinders the development of personalized nutrition plans and precision health interventions, ultimately limiting the effectiveness of autoimmune disease management strategies. Nutrition Controversies and Advances in Autoimmune Disease brings to the table more than a mere theoretical guide. It offers practical applications and case studies that bring to life the latest research and developments in the fields of food safety, nutrition, bioscience, and data algorithms. By integrating these disciplines, the book provides readers with the knowledge and tools to develop personalized nutrition plans and implement precision health interventions for autoimmune diseases, making it a valuable resource for anyone in the field. This book caters to a diverse audience, including researchers, clinicians, dieticians, nutritionists, students, academics, and food industry professionals. It is a valuable reference on the interplay between food, nutrition, bioscience, and data science for autoimmune disease management. By providing cutting-edge insights and techniques, Nutrition Controversies and Advances in Autoimmune Disease empowers readers to make informed decisions that can improve patient outcomes and advance our understanding of autoimmune diseases.

This textbook deals comprehensively with livestock production diseases and their prevention in the major species: ruminants, swine, and poultry. It gives an interdisciplinary view on pathophysiology, prophylaxis, and health management.Livestock breeding and husbandry is often accompanied by a conflict of interest between the animal´s biological requirements and economic producer needs. This conflict is increasingly gaining attention not only by producers, animal scientists, and veterinarians, but also by the public. It creates significant future challenges, which are described and addressed in this book. The main topics covered are: •the use of antimicrobials with emphasis on security and safety for producers/consumers•the impact of locomotion disorders on performance and welfare of farm animals •the interactions of gut microbiome, genetics, climate change, metabolic status and mineral homeostasis with reproduction, performance, animal health and welfare•infectious and respiratory diseases•the raising of neonatesA special section is devoted to behavioural signs indicating an impaired animal welfare. These are the basis for precision livestock farming (PLF) technology and the development of new management concepts. The present work is a valuable resource for veterinarians, students, as well as expert readers from animal and agricultural sciences, food safety and technology. Supplementary videos can be accessed online as well as directly from the print book; simply download the Springer Nature More Media App for free and scan the links with the play button.

This reference book discusses the role of synbiotics in a wide range of disease states, including cardiovascular, reproductive, metabolic, neurodegenerative, gastrointestinal, thrombotic, skin, and inflammatory disorders. It reviews the functions of probiotics in the diagnosis, prevention, or treatment of various disease states. The book further covers improving the targeting efficiency of synbiotics through advanced drug delivery systems such as nanoparticles, microparticles, liposomes, microemulsion, solid lipid nanoparticles, and nano lipid carriers. The chapter addresses the implications of oral and topical delivery of synbiotics in different diseases and presents the safety assessment of synbiotics and clinical trials associated with synbiotics containing drug delivery systems for the treatment of diseases. The book also explores the synergistic welfare of synbiotics nutraceuticals in various conditions such as chronic respiratory diseases, gut health, and neurological functions and examines the toxicological profile, and regulatory aspects of nutraceutical supplements. As such, this book is a valuable resource for academics, research and industry professionals working in Pharmaceutical Sciences, Food Biotechnology, Immunology, and Health Sciences.​

This book provides comprehensive knowledge of the methods of detection and identification of phyllosphere microbial pathogens and the management of different kinds of diseases caused by them in various crops. Interactions between pathogens and host plants result in the induction of defense responses expressed via molecular signals, from initiation of infection to systemic progression of pathogen invasion in susceptible plants and contrasting signals in resistant plants, leading to inhibition of pathogen development through activation of preinfectional and postinfectional defense responses. These are critically discussed.The author describes the intricate and complex competitive activities of the pathogens and host plants in a molecular warfare that the host plant must win to break the link in the pathogens'life cycle, allowing the development of disease management strategies based on the principles of exclusion, eradication, and immunization. Integration of strategies concerning the development of cultivars resistant to pathogens through breeding and biotechnological techniques, application of biotic and abiotic inducers of resistance to pathogens, and use of disease-free seeds and propagules that are complementary to each other along with effective cultural practices are emphasized.This book presents information gathered through an extensive literature search to help researchers and graduate students in agricultural sciences identify research gaps and successfully complete their research projects.

COVID-19 Management in the Brain and Body describes the management of patients with the novel coronavirus in their varied symptoms. Detailing this multisystem disease and the variety of organs and tissues affected, this volume features chapters on neurological systems, including brain cancer, brain embolism, and meningoencephalitis. Several systems are addressed, including conditions affecting hematological, hepatobiliary, gastrointestinal, and cardiovascular systems. Telemedicine and are also discussed. This volume is relevant for all clinicians working to ensure the best outcomes and patient care of patients with COVID-19. - Discusses the management of multisystem symptomatology, including the effects of COVID-19 on the neurological, respiratory, hematological, hepatobiliary, gastrointestinal, and cardiovascular systems - Includes select guidelines for clinics providing care for COVID-19 patients - Features individual chapter introductions, and a section on case studies to provide a comprehensive primer for each topic - Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures

This volume constitutes the refereed proceedings of Metaheuristics on 15th International Conference, MIC 2024, held in Lorient, France, during June 4–7, 2024. The 36 full papers presented together with 34 short papers were carefully reviewed and selected from 127 submissions. The conference focuses on artificial intelligence, combinatorial optimization, computer science, graph theory, evolutionary algorithms, genetic algorithms, simulated annealing, optimization, optimization problems.

Encyclopedia of Food Allergy, organized in 10 sections, with ~200 chapters, and written by world-renowned clinician-scientist authors, is the most comprehensive resource for food allergy ever compiled. With online and physical presence, intuitive and easily accessible organization of information, the reader can quickly access overview and general topics as well as detailed information to inform solutions to clinical or research questions. Research topics provide the necessary background for the novice as well as the details required for those in the field. Clinical topics provide comprehensive and practical information, with generous use of tables, figures, and key points/clinical pearls, to inform clinical decision-making, and promote evidence-based management decisions. Food allergy may affect up to 10% of the population in developed countries and appears to be increasing in prevalence worldwide, with many food allergies proving life-long, severe and potentially fatal. The last decade has witnessed a sea change response to the impact of food allergy through basic science research on the immunology, food science research on the triggers, clinical approaches to daily management, treatment and prevention, and an increasing understanding of the psychosocial and societal implications and how to address them. With the expanding breadth and depth of the field, there is no existing comprehensive resource available for those professionals interested in learning about or contributing to food allergy research and clinical care. This is a complete resource covering broad and detailed aspects of food allergy and adverse food reactions for clinicians, researchers, regulators, food industry, students and other stakeholders who need and will benefit from a rich resource with in-depth and practical information. - Presents in-depth, comprehensive coverage from an outstanding international author base of domain experts - Ideal for new researchers and clinicians who will have a single resource that includes general topics to get them started - Includes access to detailed information in their areas of work AND for many related topics that will help improve their research or clinical care

'Biological Insights of Multi-Omics Technologies in Human Diseases´ provides detailed information about the basics of multi-omic technologies including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives. The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. • Explains the in-depth role of multi-omics on drug discovery/metabolism, diseases, and highlights progress in both the research and clinical areas of computation, as well as relevant implementation experience and challenges. • Describes the practice of multi-omic technologies in the treatment of several diseases.• Includes practical application and machine learning approaches of multi-omics.

Applications of Seaweeds in Food and Nutrition provides an overview on the cultural, biological and engineering dimensions relating to seaweed as a food. With the need for sustainable and healthy foods growing, this comprehensive resource explores how seaweeds can deliver not only nutritional benefits, but also antiviral and antibacterial properties as a food additive and within food processing and manufacturing. Recent developments show that the use of seaweed extracts as a compound can prevent browning. It use in other areas such as a thickening and gelling agents in foods and cosmetics is also encouraging. There are hundreds of different varieties of seaweed known to mankind, yet very little literature is available on the processing of these'crops.'This book provides these valuable and practical insights. - Introduces the origin of seaweed consumption and its biology - Examines common seaweed varieties of industrial interest and their chemical composition - Explores the potential of robotics and AI techniques in seaweed aquaculture

The capacity of nanoparticles to interact with biological systems at the molecular and cellular levels has led to revolutionary advancements in medicine and the environmental sciences. This book focuses especially on the multifaceted roles of nanoparticles in the areas of health and disease. Keywords: Photoresponsive Nanoparticles, Cancer Treatments, Bacteria, Viruses, Wound Restoration, Inflammation Control, Nucleic Acids, Lipids, Cell Membranes, Endothelial Cells, Genotoxicity, Carcinogenicity.

The story of our evolutionary past is told in our genome sequence. Human Gene Evolution deals with the origins of human genes, describes their structure, function, organisation and expression. The text integrates our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms underlying evolutionary change.

Postbiotics: Health and Industry provides a detailed overview on the fundamentals, biological and therapeutic properties, safety, and application of postbiotics in health and industry. Sections cover the fundamentals of postbiotics, which include insights on probiotic microorganisms, postbiotics, and host–microbe interaction, analysis, and characterization of postbiotics. The book goes on to delve into the different types of postbiotics and their mechanisms. Remaining sections explore various health, pharmaceutical, and industrial applications of postbiotics. - Provides an overview on the separation, characterization, and identification of postbiotics from probiotic microbes - Includes classes of postbiotics and their mechanisms of action - Discusses the safety of postbiotics in humans and animals and the use of multiomics to understand the effect of postbiotics on human physiology - Analyzes existing regulatory framework for postbiotics

This Volume 2 of a two-volume work provides an up-to-date overview of the latest advances in live biotherapeutics research, engineered and genome-edited probiotics. It focuses on key areas within probiotics and microbiome studies in human medicine, including their translation into commercial applications. The book is divided into three sections, comprising (I) biomedical and nutritional benefits of probiotics for human health, (II) post-genomic technologies in probiotics sciences and genome engineering, and (III) biosafety aspects and prospects of biotherapeutics. The broad spectrum of industry-relevant contributions makes this work a valuable resource for industry professionals as well as researchers in functional food and feed biotechnology, applied microbiology and gastroenterology. Presenting novel and evidence-based research, this volume will drive the commercial enterprise and meets the great demand for good probiotic products in the human medical sector.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.​

Advances in Virus Research, Volume 115, the latest release in this comprehensive serial that highlights new advances in the field, includes updates on a variety of timely topics, including Plant viral nanotools, Mycoviruses, Rift Valley Fever virus entry and infection, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Virus Research series

Antibiotics: Therapeutic Spectrum and Limitations provides up-to-date information on managing microbial infections, the development and types of antibiotics, the rationale for utilizing antibiotics, toxicity considerations, and the control of antibiotic resistance in one single resource. This book also aims to provide comprehensive insights and current trends on antibiotic therapies to treat microbial infections, their mechanisms of action, and the role of modern drug delivery in improving their efficacy. Written by leading experts from around the globe, the chapters in the book covers important aspects of microbial infections including hospital acquired infections and community acquired infections and adult sepsis, examines the various types of antibiotics with different mechanisms and therapeutic uses, the global challenge of antibiotic resistance, and clinical trials, regulatory considerations, and market overview of antibiotics. Furthermore, the chapters include updated literature reviews of the relevant key topics, high-quality illustrations, chemical structures, flowcharts, and well-organized tables, all of which enable better understanding by the readers. - Provides in-depth and updated information and analyses on microbial infections, antibiotics and therapeutics, the consequences of antibiotic resistance, and the role of modern drug delivery in improving efficacy - Discusses different types of antibiotics and their mechanisms as well as traditional medicine, herbal drugs, and postbiotics in the treatment and prevention of microbial infections and management of antibiotic resistance - Contributed by global leaders and experts from academia, industry, research institutes, and regulatory agencies

Clinical Decision Support and Beyond: Progress and Opportunities in Knowledge-Enhanced Health and Healthcare, now in its third edition, discusses the underpinnings of effective, reliable, and easy-to-use clinical decision support systems at the point of care as a productive way of managing the flood of data, knowledge, and misinformation when providing patient care. Incorporating CDS into electronic health record systems has been underway for decades; however its complexities, costs, and user resistance have lagged its potential. Thus it is of utmost importance to understand the process in detail, to take full advantage of its capabilities. The book expands and updates the content of the previous edition, and discusses topics such as integration of CDS into workflow, context-driven anticipation of needs for CDS, new forms of CDS derived from data analytics, precision medicine, population health, integration of personal monitoring, and patient-facing CDS. In addition, it discusses population health management, public health CDS and CDS to help reduce health disparities. It is a valuable resource for clinicians, practitioners, students and members of medical and biomedical fields who are interested to learn more about the potential of clinical decision support to improve health and wellness and the quality of health care. Presents an overview and details of the current state of the art and usefulness of clinical decision support, and how to utilize these capabilities Explores the technological underpinnings for developing, managing, and sharing knowledge resources and deploying them as CDS or for other uses Discusses the current drivers and opportunities that are expanding the prospects for use of knowledge to enhance health and healthcare

This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases. The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upcoming advances in molecular diagnostic approaches to unravel this reservoir. Toward the end, the book reviews the advances in understanding the human urinary microbiome and its potential role in urinary tract infection. The chapter also presents the dynamics of the skin microbiome and the association of microbiota with skin disorders and therapeutic interventions. This book is an invaluable read for health professionals, medical students, microbiologists, and scientific research communities who are eager to update themselves with recent trends in microbiome research.

This journal's volume contains articles describing the latest research results on biomaterials'properties used in implantology, tissue regeneration, and bone reconstruction. The analysis of the biomimetic approach to the design and calculation of thin shells, biomechanical research of features of human gait, investigation of organic nanoparticles synthesis for use in biosensors and biomedical applications and development of an accelerated variant of the electrocardiogram processing are also presented in this edition.

Contact, Circulation, Exchange collects ten articles focusing on worked hard materials of animal origin (shell, tusk, bone, antler) ranging chronologically from the Upper Palaeolithic to the Middle Ages. The authors have varied academic backgrounds that enhance the archaeological analyses carried out, often at first hand, on numerous collections from the Old and New Worlds. Evidence of contact between past populations with distinct technical traditions is found in the dynamic imposed by using certain craft methods, such as stone pressure flaking (7,000 BC). Another kind of stimulus may have given rise to a tool with a specific use in the migration period, the sumak (300 BC-600 AD). Apart from the attraction of a novel technique or a new piece of equipment, it was the attraction of the raw material and the hunting sites that formed the guiding principle behind the mobility of groups within a territory, in early (35,000-12,000 BC) as in recent prehistory (up to 1500 AD). Weaponry, adornments and/or the animal species used are then powerful markers of the extent of trade routes and networks, and even of craftsmanship when related to village settlements (4,500-2,500 BC). In antiquity, the exotic rather than exogenous origin of materials was used to develop unique skills in the service of cults. In the diffusion of figurines, representation took precedence over the unique or sought-after nature of the material, whose origin remained nonetheless animal.

This volume on Infectious Diseases in an Encyclopedia of Sustainability Science and Technology (ESST) addresses the needs of health care providers and policy makers as well as scientists and engineers. Most of chapters in this volume deal with infectious diseases that directly affect humans, including the detailed characterization of specific pathogens, how they reproduce, how they are transmitted, and the means available to control, eliminate, or eradicate them. In this revised and updated second edition, the number of human infectious diseases covered has been significantly expanded. Other new chapters deal with current leading edge technologies for the diagnosis of pathogens; surveillance including environmental and syndromic surveillance for pathogens; requirements for quality assurance, quality control and the need for biological standards and controls to sustain high quality diagnosis and surveillance; the use of big data for personalized medicine; modeling infectious diseases; zoonotic and vector borne diseases; disease prevention with antibiotics, antivirals and vaccines; and factors that affect ecological balances leading to emergence of new diseases such as climate change and deforestation. Finally, infectious diseases that affect livestock and culture of plants for food, comfort and beauty are also addressed, since we must also consider them when discussing sustainability of humans in our ecosystem.

Characterization, Epidemiology and Management is the third volume in the Phytoplasma Diseases in Asian Countries series dedicated to the analysis of plant pathogens across Asia. Highlighting genomic studies and molecular approaches for rapid detection of phytoplasma diseases, the book discusses effective control measures for insect vectors across Asia. The chapters in this book discuss the latest biological controls and how best to manage and even eliminate phytoplasma diseases. This is an essential read for students, researchers and agriculturalists interested in plant pathology. Phytoplasma are microorganisms that are transmitted by insect vectors, infecting various different types of annuals and perennials and causing serious damage to crops across Asia. - Highlights the latest advances in diagnostic technologies - Includes up-to-date information on genome sequencing of important phytoplasma strains across Asia - Discusses the epidemiology and management of phytoplasma-associated disease

Entièrement refondue et actualisée, cette 6e édition propose une synthèse des théories, méthodes et champs d'application de la neuropsychologie.Après un panorama historique de l'évolution de cette discipline, l'ouvrage décritet commente les différentes méthodes utilisées telles que les évaluations cognitives et l'utilisation des techniques d'imagerie cérébrale, avant d'aborder les grands syndromes neuropsychologiques.Il présente ensuite, de manière détaillée, la neuropsychologie de l'enfant et de l'adulte âgé, avant d'aborder les démences, ainsi que les rééducations et prises en charge des patients.Il montre, à cette occasion, les multiples échanges de la neuropsychologie avec d'autres disciplines comme la neurologie clinique, les neurosciences, la psychologie cognitive, la psychopathologie ou la génétique.

Plant RNA Viruses: Molecular Pathogenesis and Management provides wide-ranging coverage on the recognition and signaling events between plants and RNA viruses. The book examines the molecular biology of signaling, host-virus interaction, RNA virus diversity, and how plants and cellular pathogens interact. Sections cover Virus Diversity and Diagnosis, Virus-Host Interactions and Virus Management. Specific chapters discuss classification and nomenclature of viruses, detail the molecular characteristics of viral genomes, highlight the viral manipulation of cellular key regulatory systems for successful virus infection, and discuss the movement of plant viruses into plant cells. Additional topics include RNA plant viruses and host interaction, detection and diversity of plant RNA viruses, and strategies for combating and management of plant viruses. With contributions from an international group of experts, the book is a comprehensive reference for those in research, academia, industry and anybody engaging in the study of plant viruses at the molecular level. - Provides an overview of virus genome and nomenclature - Covers plant virus biodiversity and ecology, diversity mechanisms and opportunities - Examines Plant Host-Virus Interaction - Discusses virus-vector interaction and transmission - Offers strategies for virus management, both traditional and modern

Advances in Virus Research, Volume 117, the latest release in a series that highlights new advances in the field, includes invaluable updates written by an international board of authors. Chapters in this new release include Pathogenesis of neuroinvasive flaviviruses, Cellular entry and egress of astroviruses, Rift Valley Fever virus entry and infection, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Virus Research serials

This book ‘Extremophiles: Wastewater and Algal Biorefinery'explores the potential of extremophiles/extremotolerant organisms in wastewater treatment, biorefining of algal biomass and in the treatment of industrial waste effluent. The book provides a holistic overview about the current status of extremophiles in waste water treatment and various industrial processes. The chapters comprehensively cover the scientific and research findings on various industrial applications of extremophiles such as biofuels, extremozymes, electricity generation, biofilms, microbial corrosion and waste water treatment etc. This book is an integrated source of literature for the scientists, engineers, academicians, and students working in the area of extremophiles, microbial technology and biorefinery.

Ecological Restoration and Environmental Change presents an introduction to the practice of renewing and restoring degraded, damaged, or destroyed ecosystems and habitats in the environment.The book addresses and challenges key issues which question the core values of the science and practice of restoration ecology. The author explains that the process of restoration has always been defined by human choices and examines the development of restoration practice, to describe different models of restoration with respect to balancing ecological benefit and cultural value. He develops ways to balance more actively these differing areas of concern while planning restorations. This new edition has been fully revised and updated to reflect changes in the field and the new challenges posed to restoration ecology in the face of the rapid pace of climate change. With strong coverage of North and South American, Europe, and Australia, this new edition has been expanded to also address indigenous perspectives and restoration projects in Africa, the Pacific Islands, and Asia. It places special emphasis on the need for restorationists to appreciate and understand the intricacies of planning and managing restorations in novel ecosystems. Lastly, it provides a critique of the new restoration standards published by the Society for Ecological Restoration in 2019.This book is essential reading for students on restoration ecology and conservation courses, as well as professionals and practitioners working on restoration projects.

This text aims to provide a comprehensive review of general emergency surgery, the branch of medicine that treats patients presenting to the hospital with a wide variety of emergency conditions. It includes a section focusing on clinical aspects, management, logistics, patient cohorts and perioperative considerations in the context of general emergency surgery and trauma. Other sections describe various conditions and diseases in specific anatomical structures to enable readers to easily find the information they need. Written and edited by international experts and opinion leaders in the field, this book is a valuable reference resource for general and emergency surgeons, trauma surgeons, emergency physicians and nurses. It will also be of interest to residents, students and all other healthcare professionals involved in the management of emergency surgical patients.

Supporting Sucking Skills in Breastfeeding Infants, Fourth Edition is an essential resource for healthcare professionals working with new breastfeeding families and infants. Using a multidisciplinary approach, it incorporates the latest research on infant sucking and clinical strategies to assist infants with breastfeeding. With an emphasis on skills, it focuses on normal sucking function in addition to difficulties based in anatomical, cardiorespiratory, neurological, or prematurity issues. The Fourth Edition has been extensively updated with new photos throughout and additional information on breastfeeding modifications for infants with structural issues, including micrognathia, orofacial clefts, and torticollis. The contributing authors also reflect on the latest breastfeeding research, including the mechanics of sucking, the normal anatomy of the floor of the mouth, the role of tongue tie in feeding difficulty, as well as strategies to support infants with neurological conditions.

This book provides the latest comprehensive methods for isolation and other novel techniques for marine product development. Furthermore, this book offers knowledge on the biological, medical, and industrial applications of marine-derived medicinal food substances.There has been a tremendous increase in the products derived from marine organisms for commercial application in industries every year. Functional foods of medicinal value are particularly in demand as new technology allows the stabilization of natural ingredients and their availability in pure forms to solve various human diseases. Marine flora and fauna have essential elements and trace minerals that nurture various hormones produced in the endocrine system to regulate the respective metabolisms, thereby providing a safe and healthy life to humans.The overall presentation and clear demarcation of the contents by worldwide contributions is a novel entry point into the market of medicinal foods from the sea. The exploration of marine habitats for novel materials are discussed throughout the book.The exploration and exploitation of the biochemistry of sea flora and fauna are limited, and this book extends the research possibilities into numerous marine habitats.Various approaches for extracting and applying the flora and fauna are discussed. This book will be of value to researchers, marine biotechnologists, and medical practitioners, due to the vast information, as well as industrial and medical applications of marine substances all in one place.

This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter's arrangement. The term'VLP'is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials

This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.

Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease. - Contains information on the use of probiotics in significant human diseases, including antibiotic resistant microbial infections - Presents novel applications of probiotics, including their use in vaccine adjuvants and concept of pharmabiotics - Includes case studies and human clinical trials for probiotics in diverse disease conditions and explores the role of probiotics in mitigation of the symptoms of disease

Global food security is increasingly challenging in light of population increase, the impact of climate change on crop production, and limited land available for agricultural expansion. Plant breeding and other agricultural technologies have contributed considerably for food and nutritional security over the last few decades. Genetic engineering approaches are powerful tools that we have at our disposal to overcome substantial obstacles in the way of efficiency and productivity of current agricultural practices. Genome engineering via CRISPR/Cas9, Cpf1, base editing and prime editing, and OMICs through genomics, transcriptomics, proteomics, phenomics, an metabolomics have helped to discover underlying mechanisms controlling traits of economic importance. Principle and Practices of OMICs and Genome Editing for Crop Improvement provides recent research from eminent scholars from around the world, from various geographical regions, with established expertise on genome editing and OMICs technologies. This book offers a wide range of information on OMICs techniques and their applications to develop biotic, abiotic and climate resilient crops, metabolomics and next generation sequencing for sustainable crop production, integration bioinformatics, and multi-omics for precision plant breeding. Other topics include application of genome editing technologies for food and nutritional security, speed breeding, hybrid seed production, resource use efficiency, epigenetic modifications, transgene free breeding, database and bioinformatics for genome editing, and regulations adopted by various countries around globe for genome edited crops. Both OMICs and genome editing are vigorously utilized by researchers for crop improvement programs; however, there is limited literature available in a single source. This book provides a valuable resource not only for students at undergraduate and postgraduate level but also for researchers, stakeholders, policy makers, and practitioners interested in the potential of genome editing and OMICs for crop improvement programs.

Rifted margins mark the transition between continents and oceans, which are the two first-order types of land masses on Earth. Rifted margins contribute to our understanding of lithospheric extensional processes and are studied by various disciplines of Earth Science (geology, geophysics, geochemistry).Thanks to better and wider public access to high-quality data, our understanding in these areas has improved significantly over these last two decades. This book summarizes this knowledge evolution and details where we stand today, with a series of case examples included. It is structured in a practical way, with concise text descriptions and comprehensive diagrams. Continental Rifted Margins 2 is a useful resource for students and newcomers to the rifted margin community – a'cookbook” of sorts to facilitate the reading of scientific publications and provide basic definitions and explanations.

Gab es in der Antike ein aktives Handeln gegenüber Naturrisiken? Jasmin Hettinger widmet sich den Vorsorgepraktiken, die sich im Laufe der Zeit in unterschiedlichen Regionen des Römischen Reichs herausbildeten, um sich vor Flusshochwasser zu schützen. Dazu untersucht sie anhand von literarischen, epigraphischen, archäologischen und geowissenschaftlichen Quellen, wie unter römischer Herrschaft Flüsse verwaltet, genutzt und wasserbaulich verändert wurden. Die gängigsten Praktiken – von Rechtsnormen über die Ausweisung von Überschwemmungsflächen bis hin zur künstlichen Flussregulierung – entsprachen den heutigen Methoden der Hochwasservorsorge. Auch das Wissen über natürliche Flutursachen war durchaus differenziert. Die eigentlichen Unterschiede zwischen dem römischen und dem heutigen Umgang mit Flusshochwasser sind im kulturellen Bereich zu verorten. Flüsse waren zugleich göttliche Wesen, zu denen ein reziprokes Verhältnis gepflegt wurde: Jeder Wasserbau musste entsühnt werden. Außerdem wurden Flüsse und ihre Ufer auf vielfältige Weise genutzt, sodass die naturnahen Flüsse, die beständig ihren Lauf veränderten, den Menschen ein hohes Maß an Anpassungsfähigkeit und Bereitschaft zur Vorsorge abverlangten.

Comprehensive Organometallic Chemistry, Fifteen Volume Set is the market-leading resource covering all areas of this critical sub-discipline of chemistry. Divided into 15 clear sections, it provides expert coverage of the synthesis, structures, bonding and reactivity of all organometallic compounds, including the mechanisms of the reactions. Applications of organometallic chemistry, such as the role of these compounds as reagents and catalysts for organometallic transformations, and their participation in bioorganometallic chemistry, is then covered. This is a vibrant area, as illustrated by the fact that the 2001, 2005 and 2010 Nobel prizes in Chemistry are all concerned with organometallic chemistry. This new edition will therefore again provide an invaluable and efficient learning resource for all researchers and educators looking for up-to-date analysis of a particular aspect of organometallic chemistry. - Comprehensive – CHEC IV will offer a comprehensive review of current heterocycles research and critical insight into the future direction of the field with an emphasis on useful and reliable synthesis and reactions, negating the need for individual searches in the primary literature and across various databases - Reputation – The 4th edition will match the impressive reputation of the previous editions as the go-to foundational reference in heterocyclic chemistry - Clearly structured - Meticulously organized, articles are split into 15 sections on key topics and clearly cross-referenced to allow students, researchers and professionals to find relevant information quickly and easily - Interdisciplinary - chapters written by academics and practitioners from various fields and regions will ensure that the knowledge within is easily understood by and applicable to a large audience

Pour un premier ouvrage de management intégrant la dimension territoriale au cœur de sa réflexion nous avons fait le choix d'approfondir trois volets qui sont de nature à mieux percevoir leur implication, leur gouvernance et les conditions de leur renforcement dans les processus de décision dont ils sont clairement partie prenante. Tout d'abord, les territoires doivent piloter un double défi, celui du respect des valeurs sociétales qui se construisent localement avec la nécessité d'une performance minimum pour assurer la pérennité des initiatives. Ensuite, leur participation à la gouvernance locale suppose de se renouveler et d'adapter leur comportement sous peine de se voir exclus d'initiatives ou de dispositifs dont ils ont été eux-mêmes à l'origine. Enfin, nous insistons sur la nécessité de renforcer le professionnalisme des acteurs du territoire. Leurs compétences sont nécessaires pour assumer leurs responsabilités et répondre aux attentes des populations attachées à des centres de décision en proximité.

“An excellent compendium of all things CRISPR from some of the leading minds in the field. With thorough coverage from every angle and beautifully detailed illustrations, this book is not to be missed!” Jennifer A. Doudna, Professor of Chemistry, Biochemistry & Molecular Biology, UC Berkeley; Founder, Innovative Genomics Institute; Nobel Laureate and coinventor of CRISPR technology “This journey through CRISPR biology and several of its breakthrough applications offers an exciting glimpse into one of the most beautiful and compelling fields in the life sciences.” David R. Liu,Director of the Merkin Institute at the Broad Institute of MIT and Harvard; Professor of Chemistry and Chemical Biology at Harvard University; coinventor of base editing and prime editing “A must read! The CRISPR topics, written by world-leading experts, span from the fascinating mechanistic underpinnings to the ingenious applications. One can read from start to finish or pick and choose themes. Either way, the book delivers utterly enjoyable learning!” Bonnie Bassler, Squibb Professor and Chair, Princeton University Department of Molecular Biology; Howard Hughes Medical Institute Investigator CRISPR-Cas systems have revolutionized the science of gene editing and their possible applications continue to expand, from basic research to potentially groundbreaking medical and commercial uses. Led by a distinguished team of editors, CRISPR: Biology and Applications explores the subject matter needed to delve into this fascinating area. Topics covered include: Classification and molecular mechanisms of CRISPR-Cas systems CRISPR-Cas evolution, regulation, expression, and function Uses for gene editing and modulation of gene expression CRISPR-based antimicrobials and phage resistance for medical and industrial purposes Written by internationally renowned authors, CRISPR: Biology and Applications serves as both an introductory guide for those new to the field and an authoritative reference for seasoned researchers whose work touches this evolving and headline- making science.

Rifted margins mark the transition between continents and oceans, which are the two first-order types of land masses on Earth. Rifted margins contribute to our understanding of lithospheric extensional processes and are studied by various disciplines of Earth Science (geology, geophysics, geochemistry). Thanks to better and wider public access to high-quality data, our understanding in these areas has improved significantly over these last two decades. This book summarizes this knowledge evolution and details where we stand today, with a series of case examples included. It is structured in a practical way, with concise text descriptions and comprehensive diagrams. Continental Rifted Margins 1 is a useful resource for students and newcomers to the rifted margin community - a'cookbook'of sorts to facilitate the reading of scientific publications and provide basic definitions and explanations.

This volume focuses on the potential use of probiotics in treating metabolic disorders such as diabetes mellitus, metabolic acidosis, and gut dysbiosis. Chapters draw an association between gut microbiota and its diversity with metabolic diseases like diabetes, obesity, related liver and gut disorders; gut-brain axis; increased inflammation, and a compromised immune system resulting from these manifestations and scope of intervention with probiotics. Special attention is laid on describing the mechanisms of action of such beneficial effects of probiotic administration. The ability of probiotics to decrease metabolic endotoxemia by restoring the disrupted intestinal mucosal barrier is also included.The volume is a comprehensive compilation describing the scope and application of probiotic and prebiotic therapy in treating metabolic disorders. Readers will discover how probiotics are not just confined to the microbiology industry but are showing promising results in the medical and pharmaceutical sectors.

Encyclopedia of Infection and Immunity, Four Volume Set provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases. More than 100 years after Robert Koch and Louis Pasteur established the microbial etiology of communicable diseases, the field of microbiology is experiencing a second period of rapid growth and expansion, driven by the realization that changes in host-associated microbial communities might be at the root of a broad spectrum of noncommunicable human diseases. These advances follow on the heels of recent progress in high-throughput sequencing technology, which has provided a wealth of information on the human microbiome and its physiological potential. - 2023 PROSE Awards - Winner: Finalist: Reference Works – Biological and Life Sciences: Association of American Publishers - Offers a contemporary review of current infection and immunity research, and insights into the future direction of the field - Meticulously researched and cross-referenced to allow students, researchers and professionals to find relevant information quickly and easily - Includes chapters written by academics and practitioners from various fields and regions, ensuring that the knowledge within is easily understood by, and applicable to, a large audience

Encyclopedia of Respiratory Medicine, Second Edition, Six Volume Set explores the key processes of lung diseases and their diagnosis and management. The book dissects the molecular and cellular biology, physiology and immunology that underpin normal lung function, along with the aberrations that occur in respiratory diseases, from common disorders such as asthma and COPD to rarer lung diseases such as cystic fibrosis, interstitial lung diseases and pulmonary hypertension. Written in at a time when the globe is in the grip of respiratory pandemic, lung disease has never been so prominent in the public and political conscious. This new edition will provide new researchers in respiratory medicine with a solid foundation in unfamiliar topics and will update more experienced researchers seeking to step outside their core areas of research to put their work into a broader context. - Presents a'one-stop'resource covering the entire scope of modern respiratory medicine - Brings together a truly global collaboration of some of the most authoritative voices in respiratory medicine - Provides chapters that are concise and accessible, with an authoritative introduction for non-specialists, as well as up-to-date, foundational content for those familiar with the field - Includes multimedia-rich content, including hundreds of clear and helpful illustrations that can be used as teaching aids

This book provides a collective examination of the theoretical, empirical, and clinical perspectives of pregnancy-related anxiety. Pregnancy-related anxiety is a distinct form of anxiety that is experienced by pregnant women and is characterized by pregnancy-specific fears and worries. This form of anxiety has been associated with a range of negative obstetric, neonatal, and maternal outcomes. There has been increased research interest in this form of anxiety, particularly over the last 15 years. The content is organized in three sections. The first section provides a thorough understanding of pregnancy-related anxiety, ranging from its historical development, evidence of its distinctiveness to the antecedents and outcomes of this anxiety for the mother and child. The second section examines key clinical issues around diagnosis and treatment specifically, current diagnosis/screening for this anxiety and approaches for intervention and treatment. The final section considers emerging areas of research such as pertinent issues around culture and acculturation which are key issues in an increasingly multicultural world. Moreover, the effects of pregnancy-related anxiety on the woman's broader psychosocial functioning are considered with specific chapters on body image and sexual abuse, two key areas of concern. A seminal resource, this book provides a broad examination of the topic from multiple frameworks and perspectives which sets this book apart from other books in print. This book intends to inform and stimulate future research studies, as well as increase awareness and understanding of pregnancy-related anxiety. It is a must-read for researchers, educators, clinicians, and higher education students who care about delivering better support and services to pregnant women, particularly those who are vulnerable and distressed.

With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.

Polysaccharides are natural, renewable materials that are biodegradable and biocompatible, making them ideal subjects for biomedical applications. This book focusses on the main polysaccharides, including but not limited to chitosan, cellulose, alginate, dextran, guar gum, gellan gum, pullulan, locust bean gum, pectin, xanthan gum, starch, hyaluronan and carrageenan, and their applications in drug delivery, imaging and tissue engineering. With contributions from around the world, the editors have pulled together a tightly curated set of chapters which showcase how polysaccharide-based materials are employed in a range of biomedical systems. The end result is a book in which the reader can gain a sound overview of this important class of material for biomedical applications, without scouring journal articles. Those working in materials science, biomedical and chemical engineering, and pharmaceutical technologies will find this a must-have reference.

The second and expanded edition of this award-winning book provides the most up-to-date and important efforts for improving the quality of life in communities around the world. It focuses on community improvements in relation to the interdisciplinary field of clinical sociology. The first part of the book includes updated analyses of important concepts and tools for community intervention. It discusses the importance of centrally involving community members in all phases of community development activities. Part II includes several completely new chapters and focuses on projects in a number of countries -- the United States, Brazil, South Africa, Canada, the Philippines and France. It covers topics such as establishing human rights cities; involving and empowering local communities; research in communities; the healthy cities movement; and climate change. This edition includes several new gender-focused chapters, addressing local level initiatives based on the recommendations of theCommittee on the Elimination and Discrimination Against Women (CEDAW), women in prison, and gender factors in climate risk. The appendices include profiles of outstanding practitioners and scholar-practitioners over the last 100 years. This edition includes contributions from well-known scholars and practitioners in clinical sociology and is of interest to sociologists, social policy makers, social workers, and sustainability researchers. The first edition of this book received the Distinguished Scholarly Book Award from the Clinical Sociology Division of the International Sociological Association.

'This book is about melon breeding and genetics: developments in food quality and safety'--