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The Five Forces reveals how technology is unleashing forces that will forever alter our lives, politics, and society. Learn more about nanotechnology, transhumanism, the future of space exploration and colonization, super human computers, and so much more! Discover what lies in our future: How will humans change as we merge with our machines, embracing transhumanism? What happens when intelligent algorithms make all the decisions? Should we connect our brains directly to the Internet? And are we entering an age of simulated realities? The Five Forces takes you on a journey to see what the most brilliant minds of our age are dreaming up. Hoffman reveals how new scientific breakthroughs and business ventures are poised to reshape our lives and turn science fiction into fact. With scientists in Japan creating humanoid robots, Silicon Valley biohackers boosting their IQs, and Chinese labs developing human-monkey chimeras, Hoffman gives an inside look at the limits of what's possible today and the impact these developments will have. Mass Connectivity What happens when brain chips connect our minds directly to the internet? Will we be able to boost our IQs, exchange memories, and communicate with our thoughts? Or will this turn into a nightmare, with corporations reading our minds, hackers overwriting our identities, and governments controlling our actions? Bio Convergence Now that we can decode the building blocks of life and create new lifeforms that never existed before, what comes next? Will we conquer disease, resurrect extinct species, develop superior plants and animals, create DNA-edited babies, and even spawn other intelligent beings? Human Expansionism Is it our manifest destiny to colonize Mars and extend the human race beyond the limits of our solar system? How will technologies like space travel, new materials, and nanotech transform our civilization and open up new horizons we never imagined possible? Deep Automation As our machines become capable enough to do every job better, faster, and cheaper, how will this affect society? Will we wind up delegating our most important decisions to data crunching algorithms? And does this mean our machines will end up running our economies, our corporations, and even our lives? Intelligence Explosion As soon as we create a superintelligence that far surpasses human capabilities, what will happen to us? Will we be able to control our machines, or will they eventually control us? Are we headed for a paradise of plenty, where our technology eliminates hunger, disease, poverty, and war? Or will this be the end of our reign as the rulers of the planet?

Originally published in 1933, this volume covers 3 features of British history in the 40 years prior to the First World War: the inroad made by commercial and industrial Germany on the far-flung business empire of Great Britain; the British national reaction to this German rivalry and the influence of that rivalry upon the shaping of British policy toward Germany.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Goldfrank's is the premier toxicology textbook that should be in every emergency department or poison center library. Whether you are a student, resident, or faculty, there is something here for you. If you are a toxicology fellow or poison specialist studying for your boards, this is your go-to book. I highly recommend this work… —The Journal of Emergency Medicine The best edition yet of the landmark text in medical toxicology A Doody's Core Title for 2020! Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to deliver evidence-based principles viewed through the lens of an active bedside clinical practice. In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins. Fully referenced and supported by a cohesive organization and full-color format, Goldfrank's begins with a historical perspective on medical toxicology principles and the general approach to the patient. It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special populations. The Eleventh Edition of Goldfrank's Toxicologic Emergencies is the most rigorous volume to date, driven by a precise analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis. New to this Edition: • Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and patient outcomes • New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies • New content on toxicogenomics explores its increasingly important role in predictive toxicology • Chapter-ending bulleted summaries of key points • Updated coverage of synthetics such as “K2” • Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, treatment strategies, and risk assessment tools

Drawing on examples of the hottest innovators in Silicon Valley, this step-by-step guide will show you how to develop, test and launch your impossibly big idea to success. Almost every major company today has made innovation its number one priority. Yet fewer than one in four executives believe their organizations are effective innovators. The pressure to innovate and the price paid for failure keeps rising, while most companies haven't progressed at all. They are still using the same antiquated techniques pioneered decades ago. This is why some of the biggest corporations in the world manage to lose entire markets to startups they've never heard of.In today's world, everyone will need to innovate to stay competitive. It doesn't matter if you're a startup founder, corporate executive, small business owner, freelancer or professional, there's a technology out there that's going to upend your industry. And if you aren't able to harness it to your advantage, someone else will. Innovation is no longer an option -- it's the price of admission into the business world.Make Elephants Fly is designed to help you implement the same innovation methodologies and processes as Silicon Valley startups. It will teach you:How startups come up with breakthrough products and services. How to structure innovation teams. The best ways to identify and vet new ideas. What it takes to foster a culture of innovation. How to establish a process of innovation throughout your organization.By the time you've digested this book, you will have the tools needed to take your impossibly big idea and make it fly!

'Tell me about the war'—these words launched a ten-year project in oral history by a husband-and-wife team. Howard Hoffman fought in World War II from Cassino to the Elbe as a mortar crewman and a forward observer. His war experiences are of intrinsic interest to readers who seek a foot soldier's view of those historic events. But the principal purpose of this study was to explore the bounds of memory, to gauge its accuracy and its stability over time, and to determine the effects of various efforts to enhance it. Alice Hoffman, a historian, initiated the study because she recognized the critical role of memory in gathering oral history; Howard Hoffman, the subject, is an experimental psychologist. Alice's tape-recorded interviews with her husband over a period of ten years are the basic material of the study, which compares the events as recounted in the first phase of the interviews with later accounts of the same experiences and with the written records of his company as well as the memories of fellow soldiers and the evidence of photographs and other documents. This engrossing story of World War II breaks new ground for practitioners of oral history. The Hoffmans'findings indicate that a subset of human memory exists that is so permanent and resistant to change that it can properly be labeled'archival'. In addition to describing some of the circumstances under which archival memories are formed, the Hoffmans describe the conditions that were found to influence their storage and retrieval.

The standard-setting reference in medical toxicology—trusted as the leading evidencebased resource for poison emergencies A Doody's Core Title for 2017! For decades, one name has been synonymous with the most respected, rigorous perspectives on medical toxicology and the treatment of poisoned and overdosed patients: Goldfrank's Toxicologic Emergencies. Presented in full color, Goldfrank's delivers essential, patientcenteredcoverage of every aspect of poison management. The editors and authors are recognized as preeminent scholars in their specialties and provide unmatched coverage of all aspects of toxicologic emergencies, from pharmacology and clinical presentation to cutting-edge treatment strategies. Goldfrank's Toxicologic Emergencies, Tenth Edition begins with an examination of medical toxicology principles and techniques. It then reviews the biochemical, molecular, and pathophysiologic basis of toxicology, followed by an intense focus on toxicologic principles related to special patient populations. Features Case studies enhance your understanding of the clinical application of the text material Practical focus on the pathophysiologic basis of medical toxicology The Antidotes in Depth sections delivers the expertise of toxicologists across the world as they present treatments for critically ill poisoned and overdosed patients and allow you to easily identify key issues relating to the use of complex and often unfamiliar therapies The principles of risk management, medicolegal decision making, patient safety, post mortem toxicology and the assessment of ethanol induced impairment described in chapters and Special Considerations emphasize the interface between medical toxicology, the law, and quality care

The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. - Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials:'the only such text that currently covers this area comprehensively'- Materials Today - Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank

Knowledge of and experience with the basic technique of vaginal hysterectomy is not univers al. Each surgeon must learn to identify and appreciate the dimensions of individual variation in anatomic findings and therefore surgical technical decisions and their execu­ tion from one patient to another. Unexpected surgical difficulty can be predicted, but ultimately it is dealt with retrospectively. Skilled practitioners must study the particular patient and her problem comprehensively and allow for such individual variations in find­ ings and technical needs as are necessary to the surgical solution for that patient's problem. Recognizing these factors, Drs. Hoffman and Spellacy have orga­ nized and prepared a comprehensive monograph concerning this very real clinical entity. They have reviewed the experience of con­ temporary surgeons and blended these recommendations with their own experience in a useful compendium of surgical knowledge about this important subject. Their monograph is recommended not as a replacement for the many other fine surgical texts available to the reader but as a supplement to the surgeon's library. It is for those surgeons who, having mastered the basic techniques, are in­ terested in extending the frontiers of personal knowledge of this provocative subject and safely broadening the indications for effec­ tive surgery and reconstruction. David H. Nichols, M.D., F.A.C.S., F.A.C.O.G.

Employing both large-scale surveys and in-depth interviews, the authors document the mental health effects on workers caused by the closure of four General Motor plants. They paint a portrait of how the social context in which these workers lived played a critical role in their experiences of unemployment or of keeping their jobs when others around them lost theirs. More than simply a study of unemployment and mental health, this book is also a story of coping and resilience.

I I This book is intended to guide practicing structural engineers into more profitable routine designs with the AISC Load and Resistance Factor Design Specification (LRFD) for structural steel buildings. LRFD is a method of proportioning steel structures so that no applica­ ble limit state is exceeded when the structure is subjected to all appro­ priate factored load combinations. Strength limit states are related to safety, and concern maximum load carrying capacity, Serviceability limit states are related to performance under service load conditions such as deflections. The term'resistance'includes both strength states and serviceability limit states. LRFD is a new approach to the design of structural steel for buildings. It involves explicit consideration of limit states, multiple load factors and resistance factors, and implicit probabilistic determination of relia­ bility. The type of factoring used by LRFD differs from the allowable stress design of Chapters A through M of the 1989 Ninth Edition of the AISC Specifications for Allowable Stress Design, where only the resistance is divided by a factor of safety to obtain an allowable stress, and from the plastic design provisions of Chapter N, where the loads are multi­ plied by a common load factor of 1.7 for gravity loads and 1.3 for gravity loads acting with wind or seismic loads. LRFD offers the structural engineer greater flexibility, rationality, and economy than the previous 1989 Ninth Edition of the AISC Specifications for Allowable Stress Design.

Proceedings of the NATO Advanced Study Institute on Biopolymers, Izmir, Turkey, August 27-September 5, 1984

The discovery and concept that Helicobacter pylori is associated with gastric disease including gastric cancer which is one of the most common and frequently lethal forms of malignancy, heralded a new and rapidly expanding field recognizing the emergence of many new pathogens and disease syndromes in clinical medicine, as well as basic infectious disease research. There is now an extensive and widely known literature of how H. pylori is involved in a wide variety of disease syn­ dromes. As summarized in the introductory chapter of this volume, many major advances have been made in diagnosis, both serologic and endoscopic in time of the involvement of this organism in patients with upper GI ailments as well as its presence in those who are not clinically ill. The Introduction describes the rapid development of understanding the role of this organism in disease. The basic bacteriology of H. pylori is then described in the second chapter. Diagnostic tests for detecting H. pylori infection is then highlighted, as well as the role of such infection in gastric cancer. Current knowledge concerning risk factors and peptic ulcer pathology associated with H. pylori is then described. Newer information concerning therapy of H. pylori infection and colonization is described in a subsequent chapter as well as one concerning the effects of anti­ biotics on H. pylori infection. The extensive literature on natural substances with anti-H.

Created with the idea that a child's diet should be healthy and fun, this inviting and easy-to-use cookbook features more than 100 delicious allergy free dessert recipes the whole family will enjoy. From birthday cakes and cupcakes to chocolate-chip cookies and banana cream pie, these recipes substitute rye flour, carob, almond milk, and other ingredients for foods children may be allergic to. This second edition includes updated substitution charts enabling any cook to convert family-favorite recipes into allergen-free delights, and a buying guide shows where to find special ingredients. There is even a chapter covering breakfast ideas, including pancakes, smoothies, waffles, and granola bars. It addresses the allergy and environmental food concerns that parents and caregivers face today as more and more children are diagnosed with multiple food allergies. Helpful tips cover how to avoid allergic foods while traveling, great snacks to take along for the ride, and how to create an allergy-free home.

Most research on the president's relationship with the public focuses on modern presidents because they frequently give speeches in the attempt to build public support for their policy goals. Expanding the concept of presidential communication beyond policy speeches, Popular Leadership in the Presidency: Origins and Practice reveals the extent to which presidents have always communicated with the public. And it is not simply the existence of public communication that is significant, but the fact that structural elements of the presidency encourage a connection with the people. The fact that the executive consists of one individual, the symbolic authority that devolves on the president as the sole national leader, and a selection process that in practice turned out to be popular all encourages a relationship with the people. An examination of the first four presidents demonstrates the broad range of public persuasion practiced by early presidents as well as the way in which the structural encourages that behavior.

A one-stop Desk Reference, for Biomedical Engineers involved in the ever expanding and very fast moving area; this is a book that will not gather dust on the shelf. It brings together the essential professional reference content from leading international contributors in the biomedical engineering field. Material covers a broad range of topics including: Biomechanics and Biomaterials; Tissue Engineering; and Biosignal Processing• A fully searchable Mega Reference Ebook, providing all the essential material needed by Biomedical and Clinical Engineers on a day-to-day basis. • Fundamentals, key techniques, engineering best practice and rules-of-thumb together in one quick-reference.• Over 2,500 pages of reference material, including over 1,500 pages not included in the print edition

Concise,'at the bedside'guidelines for toxicologic emergencies--derived from the premier reference in the field This practical and portable bedside manual is condensed for instant application from the masterwork regarded for a quarter of a century as the'gold standard'reference in the field of emergency toxicology: Goldfrank's Toxicologic Emergencies. You will find trusted information on the scientific principles that explain how toxins affect vital signs, neurotransmitters, metabolic processes, and organs and systems throughout the body. Covers the full range of toxins Includes pharmaceuticals, recreational drugs, and substances of abuse; food and plant toxins; envenomations; household toxins; pesticides and herbicides; rodenticides; metals; poison gases; and environmental toxins Systematically reviews toxicokinetics, pathophysiology, clinical manifestations, diagnostic testing, and management for each toxin Provides'Antidotes in Brief'--at-a-glance guides to specific antidotes and their primary applications Authoritative answers--at your fingertips How to manage the poisoned or overdosed patient What techniques effectively eliminate toxins Which imaging modalities yield the best results More

The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials.• Provides comprehensive coverage of principles and applications of all classes of biomaterials• Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics• Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field• Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites• Endorsed by the Society for Biomaterials

This comprehensive reference emphasizes the dynamic events that occur in the maintenance and repair of blood vessels in health and abnormalities that may result from dysregulation of inflammatory and immune responses in disease. The editors have assembled authors and topics that bring new concepts about cell and molecular biology to the clinician t

This book is intended to guide practicing structural engineers familiar with ear­ lier ACI building codes into more profitable routine designs with the ACI 1995 Building Code (ACI 318-95). Each new ACI Building Code expresses the latest knowledge of reinforced concrete in legal language for safe design application. Beginning in 1956 with the introduction of ultimate strength design, each new code offered better uti­ lization of high-strength reinforcement and the compressive strength of the con­ crete itself. Each new code thus permitted more economy as to construction material, but achieved it through more detailed and complicated design calcula­ tions. In addition to competition requiring independent structural engineers to follow the latest code for economy, it created a professional obligation to fol­ low the latest code for accepted levels of structural safety. The increasing complexity of codes has encouraged the use of computers for design and has stimulated the development of computer-based handbooks. Before computer software can be successfully used in the structural design of buildings, preliminary sizes of structural elements must be established from handbook tables, estimates, or experienced first guesses for input into the com­ puter.