Search

Das große Standardwerk zur klinischen Neurologie liegt jetzt unter der Federführung des international renommierten Herausgeberteams und der Mitarbeit von über 150 FachexpertInnen als erweiterte und komplett überarbeitete Neuauflage vor. Die aktuellen Erkenntnisse zum Stand von Klinik, Verlauf und Therapie neurologischer Erkrankungen werden systematisch zusammengefasst und für die praktische Anwendung gewichtet - sowohl für häufige als auch für seltene Krankheitsbilder. Zudem profitiert die 8. Auflage von neuen Kapiteln zu funktionellen Bewegungsstörungen, dissoziativen Anfällen, spinaler Muskelatrophie sowie zu neurologischen Nebenwirkungen von Tumor-Therapien. Das Werk wurde konzeptionell und didaktisch weiterentwickelt, um den heutigen Anforderungen des modernen und zunehmend digital geprägten Klinikalltags gerecht zu werden. Die Bewertungen von Evidenzlevels und Empfehlungsstärken der relevanten Therapien sowie klinische Pfade veranschaulichen die Best Practice. Das etablierte Werk, welches die gesamte Neurologie abbildet, ist aus der alltäglichen Arbeit von FachärztInnen und AllgemeinmedizinerInnen in Klinik und Praxis sowie einer erfolgreichen Aus-, Fort- und Weiterbildung nicht mehr wegzudenken.

This book focuses on the multifarious aspects of ‘fuzzy boundaries'in the field of discourse studies, a field that is marked by complex boundary work and a great degree of fuzziness regarding theoretical frameworks, methodologies, and the use of linguistic categories. Discourse studies is characterised by a variety of theoretical frameworks and disciplinary fields, research methodologies, and lexico-grammatical categories. The contributions in this book explore some of the nuances and implications of the fuzzy boundaries in these areas, resulting in a wide-reaching volume which will be of interest to students and scholars of discourse studies in fields including sociology, linguistics, international relations, philosophy, literary criticism and anthropology.

As Artificial Intelligence (AI) technologies rapidly progress, questions about the ethics of AI, in both the near-future and the long-term, become more pressing than ever. This volume features seventeen original essays by prominent AI scientists and philosophers and represents the state-of-the-art thinking in this fast-growing field. Organized into four sections, this volume explores the issues surrounding how to build ethics into machines; ethical issues in specific technologies, including self-driving cars, autonomous weapon systems, surveillance algorithms, and sex robots; the long term risks of superintelligence; and whether AI systems can be conscious or have rights. Though the use and practical applications of AI are growing exponentially, discussion of its ethical implications is still in its infancy. This volume provides an invaluable resource for thinking through the ethical issues surrounding AI today and for shaping the study and development of AI in the coming years.

This 9-volume set covers a wide range of topics, including: childhood vasculitic stroke; anosognosia; stroke-rehabilitation games; electrical stimulation; vasculitis.

This practical guide provides an algorithm for diagnosis and treatment, from ‘having some problem with vision', via diagnosis of cause and background, to treatment and eventually to rehabilitation.Following on from introductory sections devoted to the role of neuro-ophthalmology, recent developments in the field, and an overview of neuro-ophthalmological examinations, there are sections devoted to the different parts of the visual system, and finally a section on rehabilitation.Neuro-ophthalmology is aimed at ophthalmologists, neurologists, neurosurgeons, traumatologists, neuroradiologists, experts in cardiology and stroke, and trainees in these areas. It will also be of interest to neuro-rehabilitation specialists, neuropsychologists, and those working in typhlopedagogy and health informatics.

Ischemic stroke (IS) is due to the sudden occlusion of a cerebral artery with the consequence of a critical reduction in cerebral blood flow in a localized region of the brain. It represents the second cause of death and the leading cause of neurological disability in developed countries. In this book, the authors discuss the symptoms, prevention and recovery strategies for ischemic stroke. Topics include the standard, current and new potential treatments of acute phase, prevention and rehabilitation of IS; ischemic stroke susceptibility gene research; the dual roles of inflammatory mediators in IS; modulation of protein kinase C isoforms as a potential treatment in IS; perioperative ischemic stroke; role of transcranial doppler ultrasonography in cerebrovascular disease; and management of carotid stenosis.

Myopathies are a clinically and genetically heterogenous group of muscle diseases characterized by pathologic changes in muscle fibers that compromise their contractile ability. The authors of this book have gathered new research from across the globe and topics discussed in this compilation include inherited myopathies with distinct clinical manifestations; muscle biopsy as a diagnostic procedure in suspected myopathies; inflammation in dysferlinopathies; mitochondrial disorders; dysphagia in the myopathies; and aB-Crystallin (HSPB5) and myofibrillar myopathies.

Our understanding of human polyomaviruses has evolved profoundly in the last fifteen years, creating an urgent need for an updated resource. Drs. Khalili and Stoner have collected the contributions of renowned researchers and clinicians in this cutting-edge volume. Human Polyomaviruses: Molecular and Clinical Perspectives presents in-depth analyses, comprehensive reviews, and timely assessments of recent discoveries and ongoing controversies focused on these important viral pathogens. Beginning with an historical perspective, this book covers up-to-date investigations into the molecular biology and pathogenesis of human polyomaviruses. All aspects of these persistent infections are subsequently covered, including clinical issues, from diagnosis to information on treatment and drug trials. Central topics are: BK virus JC virus Simian virus 40 (SV40) and its potential as a human pathogen Progressive multifocal leukoencephalopathy (PML) This reference is a superb indoctrination for graduate students, medical students, high-level undergraduates, and anyone engaged in the study of DNA viruses and their molecular biology, evolution, transmission, and pathological potential.