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This book comprehensively addresses various aspects of breast cancer survivorship issues, emphasizing the importance of interdisciplinary teamwork in their management. What sets this work apart is its collaborative approach, incorporating insights from diverse healthcare professionals.With increasing survival rates and prolonged disease-free periods, there is a strong need in managing breast cancer treatment in the short and long-term. This book underscores the necessity of addressing often overlooked or underestimated issues during the survivorship phase, contributing to enhance the knowledge from both the patient and healthcare provider perspectives.The book's content is thoughtfully organized to ensure accessibility, targeting not only specialized readers but also undergraduate health professional students, including physical therapists and nurses, who intend to delve deeper into the field of breast cancer care.This book will be an invaluable guide not only for healthcare professionals such as oncologists, hematologists, surgeons, physical therapists, nurses, nutritionists, and psychologists, but also for undergraduate students pursuing bachelor's degrees in these fields. Additionally, it offers valuable insights and support to breast cancer survivors on their journey to recovery.

This manual covers all possible aspects of managing a child with differences in sex development, an entity easily missed by the unsuspecting clinician. Managing such children is challenging due to various processes (genetic, hormonal, environmental, chromosomal, and environmental) involved in developing gonads and brain imprinting. The entity of Gender dysphoria adds further to this complexity. With a global uproar caused by the cropping up of medicolegal issues concerning sex allotment and sex of rearing, a need is felt to know about the line of approach to address the problems of management of these children, which does not stop at medical and surgical treatment. Whereas many social and legal organizations are relentlessly working for the cause of such children, there is a lack of comprehensive literature on the round management of such children, which makes the book more of an essential addition to the existing reading material. Esteemed writers give all these aspects and explain lucidly with the help of tables, figures, and diagrams.

This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.

As a single-source volume on intraoperative neurophysiological monitoring (IOM), previous editions of this celebrated resource amounted to a mission statement from the pioneer generation in intraoperative neurophysiology, converting insights, techniques, and perspectives into tools providing clinical utility for the assessment of the nervous system in patients who could not be assessed by a standard neurological examination. Now directed by a new generation of experts, this thoroughly illustrated Third Edition is updated with new case material, images, videos, practice guidelines, references, and technologies, and is intended for those who encounter IOM in the operating room and intensive care unit, including anesthesiologists, technologists, neurophysiologists, surgeons, and nurses, as well as graduate students and trainees. Offering topical, applicable information, this accessible reference and teaching tool provides practical knowledge to help students, trainees, andteam members better understand one another's roles, thereby improving patient safety and care.

••Selected for Doody's Core Titles® 2024 in Endocrinology/Metabolic Disease•• Endocrine Hypertension: From Basic Science to Clinical Practice bridges the gap between scientists and practicing clinicians by providing a comprehensive overview on all forms of endocrine hypertension, covering epidemiological aspects, pathophysiology, clinical presentation, laboratory evaluation and practical management aspects of endocrine hypertension. This book is a great resource for endocrinologists, physicians, general practitioners and researchers who are eager to understand the complex facets of endocrine hypertension. Endocrine hypertension is a term used to describe a group of endocrine pathologies that cause an elevation of blood pressure, estimated to account for up to 10% of all hypertension cases. Although common, this clinical condition is often overlooked. Patients with this condition are at risk of late diagnosis, delayed treatment and detrimental health consequences.Provides a comprehensive overview on all forms of endocrine hypertensionDiscusses molecular physiology and pathophysiology of various endocrine hypertension related conditions and offers guidance to diagnosis and management of endocrine hypertensionIncludes instructional overview figures, diagrams, flowcharts, scan images and tables to enhance understanding

This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic response as a surrogate endpoint of survival. It also illuminates clinical management of patients with organ-confined GU tumors, such as side effect management and perioperative safety, before providing an overview of biomarker use for patient selection across the early-stage GU malignancies. Lastly, the book provides the reader with the most up-to-date data emerging from clinical trials involving immunotherapy in early-stage GU malignancies. Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management provides a comprehensive review of the field, serving as a valuable resource for urologists, medical oncologists, pathologists, fellows in urologic oncology, upper-level residents training in urology and medical oncology, as well as pharmacists interested in RCC clinicians.

Cerebrospinal Fluid and Arachnoid Space Volume 2: Pathology and Disorders is the first book devoted to the comprehensive clinical anatomy of the cerebrospinal fluid for neurosurgeons, neurologists, and neuroscientists. Knowledge of the cerebrospinal fluid (CSF) and the subarachnoid space is necessary for almost all fields of medicine. The book covers a wide swath of topics related to CSF with a focus on topics relevant to neuroscience specialists including researchers, neurologists, neurosurgeons, and neuroradiologists. Topics span from neuroanatomy, neurophysiology, CSF in different disease states and more. Various fresh and fixed cadaveric photographs helps readers obtain a better understanding of anatomy and complications related to CSF. - First comprehensive book devoted to clinical anatomy of cerebrospinal fluid and subarachnoid space - Edited by neuro-anatomists and neurosurgeons, giving it a multimodal perspective - Nerves and vessels color-coded to differentiate from other tissues

In spite of great improvements in prehospital, critical care, and surgical management, traumatic brain injury is still a leading cause of death and disability resulting in great socioeconomic burden. This book provides a comprehensive and practical perspective of the management of traumatic brain injury, from prehospital setting to discharge. Even more, the book highlights the importance of pathways (Trauma Center and Neurocritical Care Unit) and the central role of the specialized neurocritical care team and neurological critical care units in the practice of neurocritical care. Encouraging a practical, protocol-driven, multidisciplinary approach for both adult and pediatric patients, the authors provide a methodological description of the diagnostic and therapeutic management of patients with traumatic brain injury throughout the patient journey. Neuromonitoring assumes predominant importance, with an increasing role of noninvasive monitoring (near-infrared spectroscopy, Pupillometry, transcranial color Doppler-TCD, transcranial color duplex-TCCD, and optic nerve ultrasound) and neurophysiology (electroencephalography and evoked potentials) for early recognition of complications and rapid assessment of the effectiveness of medical treatment. However, the increasing amount of data increases the complexity of interpreting the collected information. The basic principles of multimodal monitoring and the computer-assisted method are presented to provide an overview of the future direction regarding the integration and interpretation of different data obtained from various techniques.Paying particular attention to prognosis and treatment-limiting decisions, the authors reviewed the critical role of neurorehabilitation and the clinical and bioethical perspective on brain death, organ donation, and communication with the family.

The monograph aims to present the recent scientific knowledge on body sensations, i.e., conscious experiences that are localized or felt in the body from an internal perspective, regardless of their sensory origin. It summarizes the basic philosophical, evolutionary, neuroanatomical, psychological, and pathological aspects of the topic. Moreover, related phenomena, such as emotions, the placebo and nocebo effect, complementary and alternative medicine, and mind-body practices are discussed from the perspective of body sensations.

This book covers all forms of Congenital Adrenal Hyperplasia (CAH) and provides a comprehensive overview of accompanying reproductive problems. Affected individuals may exhibit low fecundability, infertility, recurrent miscarriages, painful sexual intercourse, sexual orientation changes, etc. If not diagnosed and treated properly, their children may also experience developmental disorders of the external genitalia. Depending on the defects in enzymes, severity of the mutations and residual enzymatic activities, the clinical presentation may differ from patient to patient. As these disorders are encountered relatively rarely, many cases are either undiagnosed or inappropriately treated. Given its scope, this book offers a valuable guide for gynecologists, endocrinologists, pediatricians, and professionals in reproductive medicine, as well as GPs, practicing physicians, medical students and residents.

Trusted for more than 50 years by pathologists in practice and in training, Scheuer's Liver Biopsy Interpretation is a well-organized, superbly illustrated guide designed to help solve diagnostic problems at the microscope. Authored by renowned expert Dr. Jay Lefkowitch and reflecting the extensive experience of the late Dr. Peter Scheuer, this practical text contains technical tips, diagnostic clues, and pearls on all aspects of liver pathology diagnosis, including acute and chronic hepatitis, biliary tract diseases, childhood disorders, and hepatic neoplasms – as well as ancillary topics such as biopsy assessment, laboratory techniques, normal liver histology, and transplantation. Throughout the text, histopathologic features are correlated with clinical features, molecular genetics, and immunohistochemistry to provide a practical account of how pathology impacts the diagnosis and management of liver disease. - Covers key topics such as genomic alterations in liver tumours, diagnosis of acute liver allograft rejection, scoring systems for non-alcoholic fatty liver disease, and discussions of immunohistochemical features wherever relevant. - Presents the latest information on next generation sequencing and drug-induced liver injury, including adverse reactions to new biologics and alternative medicines to help both the clinician and pathologist avoid diagnostic errors. - Features many new illustrations, including over 300 large, full-color and fully annotated photomicrographs that illustrate a wide range of pathologic appearances and help identify each diagnostic entity under discussion. - Offers coverage of cytopathology in the assessment of liver tumors to provide further clinical clues to diagnosis. - Provides basic overview of major histopathologic diagnostic problems in paediatric liver biopsy, including biliary atresia and several types of progressive familial intrahepatic cholestasis - Provides new and updated algorithms, tables and images highlighting key features of each diagnostic entity – ideal as a concise review during sign out or for studying and board preparation.

Das Standardwerk für die dreijährige Zusatzweiterbildung Kinder-Endokrinologie und –Diabetologie vereint zwei Subdisziplinen der Pädiatrie. Der Bogen spannt sich von den physiologischen Grundlagen bis hin zum speziellen Wissen über bestimmte Krankheitsentitäten und Untersuchungstechniken. Zudem werden Referenzwerttabellen für unterschiedliche Mess- und Laborwerte bereitgestellt.

This second updated volume on breast cancer provides a comprehensive overview of its clinical management and current therapies. Updated to reflect the changes in breast cancer staging, the progress in immunotherapy approaches, as well as the latest guidelines for therapies, this book brings readers up to speed with the latest therapeutic regimens in breast cancer and provides an in-depth account of current and new therapeutic approaches. The most important phase III trials, high quality meta-analysis, consensus reports and guidelines are extensively discussed in this new edition and provide the reader with the most up-to-date information.Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget'sdisease and phyllodes tumors and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must-have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

Dieses Frauenärztlichen Taschenbuch gibt eine Übersicht zur Diagnostik und Therapie von Myomen. Neben epidemiologischen Daten erfolgt die Darstellung wesentlicher diagnostischer Methoden mit Bildmaterial.Der Schwerpunkt des Buches liegt auf der medikamentösen Therapie von Myomen. Neben der kurzen Darstellung anderer Therapieverfahren werden einzelne medikamentöse Verfahren detailliert beschrieben. Ein besonderer Fokus wird auf die Langzeittherapie mit Progesteronmodulatoren gesetzt, dargestellt in typischen Kasuistiken. Zusammenfassend sind die Ergebnisse eines Expertenmeetings einschließlich eines Therapiealgorythmus dargelegt.

This book focuses on the characteristic of glaucomatous optic neuropathy and its relationship with cerebrospinal fluid (CSF) pressure. It also explores the potential novel methods to manage glaucoma by adjusting CSF pressure. This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial. This book contains over 40 chapters, including numerous images from clinical patients and experiments on gross anatomy, pathological tissue, and immunohistochemistry, electronic speculum etc. The ophthalmologists and researchers can also benefit from the clinical cases. We hope this book serves as a clinical guidance with practical significant for the understanding, prevention and diagnosis of glaucoma.

Nearly 25 years have passed since eosinophilic esophagitis (EoE) has been recognized as an own, distinct entity. Initial doubts about the existence of this new disease were quickly eliminated by its dramatic increase. Despite intensive research activities with meanwhile more than 300 scientific publications per year, essential questions of pathogenesis and therapy are still unclear today. Nevertheless, it is worthwhile to draw up an interim balance. The purpose of this 2nd edition is to summarize the key parameters of EoE in an understandable way to empower clinicians to care for EoE patients.

This book offers the reader sound advice on how to perform optimal conventional pediatric radiographs and how to obtain quick and easy organ dose estimates in order to improve the optimization process in pediatric imaging. Clear guidelines are provided for minimization of the radiation exposure of children through optimization of the radiation exposure conditions, and conversion coefficients are presented for calculation of the organ doses achieved in organs and tissues during conventional pediatric radiography, taking into consideration both optimal and suboptimal radiation field settings. Previously published conversion coefficients have failed to represent the variation in radiation field settings in daily clinical routine, which has made it difficult for the pediatric radiologist to estimate the impact of the field settings on absorbed doses in organs and tissues. The aim of this book, co-written by a pediatric radiologist, a physician and physicist, and a medical radiation technologist, is to address this issue by providing, for the first time, a thorough overview of clinical radiation field settings and their implications for radiation protection. An accompanying volume is devoted to fluoroscopy.

Knapp 25 Jahre sind vergangen, seit die Eosinophile Ösophagitis (EoE) als eigenständiges Krankheitsbild erkannt worden ist. Heute belegen Fallberichte aus allen Kontinenten, dass die EoE weltweit zu einem relevanten Problem geworden ist und sowohl Patienten, Ärzte als auch Gesundheitssysteme erheblich belastet. Trotz intensiver Forschungstätigkeit mit mittlerweile über 300 wissenschaftlichen Publikationen pro Jahr sind wesentliche Fragen der Pathogenese und der Therapie auch heute noch nicht restlos geklärt. Trotzdem lohnt es sich, eine Zwischenbilanz zu ziehen. Dieses Buch hat das Ziel, die wesentlichen Eckpunkte der EoE in verständlicher Form zusammenzufassen, um Ärzte zu befähigen, ihre EoE-Patienten bestmöglich zu betreuen.

This book provides an up-to-date review of the risk factors and genetics influencing the development of this rare disease. This volume presents clinical features and recent advances in histopathology and molecular profiling are analyzed, providing a valuable aid to clinicians in tailoring treatment to both the patient and the tumour. Readers will find important insights into the most effective strategies for making or negating a diagnosis of MBC. Within this timely volume, consideration is also given to the psychological needs of men with breast cancer alongside a discussion of the most effective support methods. The surgical management of the disease is examined, together with algorithms for local and systemic therapy. Owing to the problem of late diagnosis in MBC, many men have advanced or disseminated disease at diagnosis and, as such, the evidence-based management of these cases is reviewed. Male Breast Cancer concludes with a discussion on determiningprognosis and the likely future developments in MBC with a focus on improved diagnosis and survival. Male Breast Cancer will be of interest to breast surgeons, oncologists, breast radiologists, breast histopathologists and breast care nurses worldwide.

This second volume of the handbook on breast disease provides a comprehensive overview of its clinical management and current therapies. It brings readers up to speed with the latest guidelines and therapeutic regimens in breast cancer and provides and in-depth account of current and new therapeutic approaches. Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget's disease and phyllodes tumors, and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must- have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain aninterdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental, and clinical data specifically focused on AI resistance in breast cancer. The volume will include three sections. The first section covers general knowledge about aromatase inhibitors, including regulation of aromatase genes, and structure and function of aromatase protein. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance. Breast cancer is the most common female cancer and AIs significantly improve treatments outcomes compatibly to previously used endocrine treatments. However 10-15% of post-operative patients develop a relapse during adjuvant treatment with AIs; about 25-50% of the patients do not respond to AIs in neo-adjuvant or metastatic setting, and the majority of metastatic patients who initially respond develop resistance within 3 years. There is an important need to understand these mechanisms of resistance in order to develop methods of preventing or overcoming the resistance to AIs, which will ensure a more successful outcome in treating breast cancer.

Neurochirurgie up to date Neurochirurgie – kaum ein anderes Fachgebiet stellt so hohe Anforderungen an Geschick und aktuelle Kenntnisse des behandelnden Facharztes. Die neuen Ansätze in der „Hightech-Medizin“ eröffnen effektive Möglichkeiten für Diagnostik und therapeutische Interventionen. Darüber hinaus ist aber auch eine interdisziplinäre Kooperation unabdingbar, um die bestmögliche Behandlung des Patienten zu gewährleisten. Die „Neurochirurgie“ von Moskopp und Wassmann bündelt die Fachexpertise von renommierten, erfahrenen Klinikern aus Neurochirurgie und angrenzenden Gebieten und Setzt mit der grundlegend aktualisierten und erweiterten 2. Auflage wieder Maßstäbe. - Das umfassende Lehr- und Referenzwerk für den gesamten deutschsprachigen Raum: Handbuch für die Aus- und Weiterbildung zum Facharzt für Neurochirurgie und interdiziplinäres Nachschlagewerk - Hochrangige Fachvertreter aus Neurochirurgie und angrenzenden Spezialgebieten: gesichertes und aktualisiertes Wissen von über 100 ausgewiesenen klinischen Experten - Neu in der 2. Auflage: - Berücksichtigung neuropädiatrischer Belange - Ausweitung spezieller zerebrovaskulärer und spinaler Aspekte - Zahlreiche neue Beiträge (u.a. Hirntumoren im Kindesalter, Glomustumoren, Thoracic-outlet-Syndrom, prächirurgische Epilepsiediagnostik, neurovaskuläre Dekompressionen bei Neuralgien) - Abstimmung auf die aktuelle WBO und Empfehlung zur Ausbildung zum Facharzt für Neurochirurgie - Refresher-Fragen zum Facharztwissen online KEYWORDS: Neuroanatomie, Hirntod, Koma, Neurodiagnostik, interdisziplinäre Neurochirurgie, funktionelle Neurochirurgie, pädiatrische und geriatrische Neurochirurgie, Schädel-Hirn-Traumata, intrakranielle und -spinale Blutungen, Gefäßmalformation, ZNS-Tumoren, ZNS-Infektionen, Erkrankungen im Bereich des Liquorsystems, Läsionen des kraniozervikalen Übergangs, Stenosen und Lähmungen, Myelopathien, radikuläre Syndrome, neurologisch-neurochirurgische Begutachtung, Facharztaus- und -weiterbildung, Facharztprüfung, Praxismanagement

1897 wurde unter dem ersten Ordinarius für Kinderheilkunde der Medizinischen Fakultät Graz, Prof. Theodor Escherich, die erste Röntgeneinrichtung in einem Kinderkrankenhaus in Europa installiert. Bis in die 50er Jahre gehörte das Erlernen der gebräuchlichen Röntgenuntersuchungen zur Ausbildung eines Kinderarztes. 1963 wurde die European Society of Pediatric Radiology in Paris gegründet und auf dem Kinderärztekongress in Köln die Arbeitsgemeinschaft Pädiatrische Radiologie, aus der die Gesellschaft für Pädiatrische Radiologie der Kinderradiologen des gesamten deutschen Sprachraumes hervorging. Die Entwicklung von Sonographie und MRT beeinflusste die Kinderradiologie grundlegend. Ihr konsequenter Einsatz senkt die medizinisch verursachte Strahlenexposition bei Kindern und Jugendlichen weitestgehend.Dieses Buch gibt einen detaillierten Überblick über die Entwicklung und damit auch über die Bedeutung der Kinderradiologie in Deutschland, den Niederlanden, Österreich und der Schweiz.

This is a comprehensive, one-stop online book relating to all areas of pregnancy and birth. The second edition of this easily searchable guide is edited by eminent experts in the field and includes new contributions from international authors. It will be an ideal reference for Maternal-Fetal Specialists and Generalists wanting an authoritative answer on any point. Key features: •Grouped in to six topics (modules) for convenience•Electronic search facility across all chapters•Approximately 700,000 words of text, 7000 references, 300 figures (including 100 in full colour), and 200 tables available to search Key topics: •All common pregnancy and birth related problems such as diabetes and pregnancy•Many rarer complications such as protozoan infections•Fetal assessment, which is absolutely central to MFM practice•Medico-legal aspects•Sickle cell disease – a major problem for patients of African descent New chapters include: •Recurrent early pregnancy losses•Invasive hemodynamic monitoring•Chronic and acute hypertension•Neurological disorders•Maternal obesity•Assessment of fetal genetic disorders•First and second trimester screening

Dermatology, edited by world authorities Jean L. Bolognia, MD, Joseph L. Jorizzo, MD, and Julie V. Schaffer, MD, is an all-encompassing medical reference book that puts the latest practices in dermatologic diagnosis and treatment at your fingertips. It delivers more comprehensive coverage of basic science, clinical practice, pediatric dermatology, and dermatologic surgery than you'll find in any other source. Whether you're a resident or an experienced practitioner, you'll have the in-depth, expert, up-to-the-minute answers you need to overcome any challenge you face in practice. Find answers fast with a highly user-friendly,'easy-in-easy-out'format and a wealth of tables and algorithms for instant visual comprehension. Get full exposure to core knowledge with coverage of dermatology's entire spectrum of subspecialties. See just the essential information with'need-to-know'basic science information and key references. Expedite decision making and clarify complex concepts with logical tables, digestible artwork, and easy-to-grasp schematics. Visualize more of the conditions you see in practice with over 3500 illustrations, of which over 1,400 are new: 1,039 clinical images, 398 pathology slides, and 152 schematics. Stay at the forefront of your field with updated treatment methods throughout, as well as an increased focus on patients with skin of color. Get an enhanced understanding of the foundations of dermatology in pathology, the clinical setting, and dermoscopy with a completely rewritten introductory chapter. Better comprehend the clinical-pathological relationship of skin disease with increased histologic coverage. Bolognia's Dermatology is the ultimate multimedia reference for residents in training AND the experienced practitioner.

O livro de dermatologia mais abrangente da atualidade com revisão científica da Sociedade Brasileira de Dermatologia. A 2ª Edição da obra Dermatologia, que já é referência no Brasil e no mundo, agraciada com o Highly Commended 2008 da British Medical Association, foi elaborada com ênfase na aprendizagem visual para ser usada semanal ou mesmo diário pelos dermatologistas, de forma que ofereça um fácil contato e a experiência necessária de fornecer informações atualizadas, tanto precisas quanto práticas.

For over 40 years Scheuer's Liver Biopsy Interpretation has been an invaluable resource for the pathologist in practice and in training in helping to solve diagnostic problems at the microscope. Lavishly illustrated in full color throughout it covers all aspects of liver pathology from the normal, the hepatidities, childhood disease and neoplasms. Copious technical tips and diagnostic'pearls'reflect the extensive experience and insight of the late Peter Scheuer and Jay Lefkowitch.. Throughout the text histopathologic features are correlated with clinical features to provide a practical account of how pathology impacts the diagnosis and management of liver disease.Well written, complete and concise quick reference.Helps the practicing and trainee pathologist solve diagnostic problems at the mircroscope.High quality color images complement the text throughout.Provides the user with a complete visual guide to each entity and assists in the recognition and diagnosis of any tissue sample under the microscope.Practical tips and “hands on” advice from two of the world's leading experts in liver pathology. Provides the trainee and general surgical pathologist with time saving diagnostic clues when dealing with difficult specimens.Glossary of frequently used terms and descriptions used in the pathology report contained at the end of the book. Useful quick reference for trainee pathologists and clinical hepatologists who may be unfamiliar with many of the terms and descriptions. Will assist in the writing and reading of a pathology report.A selection of a few general reading references at the end of each chapter.Directs the trainee or practitioner to the most relevant and authoritative sources of further information and study.A brand new chapter:'Practical Principles in Biopsy Assessment'. Focus is on interpretation rather than a mere listing of pathological changes. The initial overview of the biopsy specimen provides critical clues to diagnosis and a highly illustrated guide to ddx will be of enormous help in avoiding diagnostic errors.Expanded coverage throughout, especially of liver tumours, pediatric fatty liver disease, neonatal cholestasis. Keeps the user apprised of the key areas of growth and development in diagnosis and interpretation.Histopathology correlated with molecular genetics and immunohistochemistry whenever clinically relevant. Keeps the user up-to-date with all of the latest tools for performing a complete and accurate diagnosis.Many new high-quality colour illustrations. Helps the user identify a wide variety of pathologic lesions.Text and images available online via Expert Consult.

Le «Traité de pneumologie» dont la 1ère édition a été publiée sous la direction du professeur Aubier en 1997, a immédiatement été reconnu comme le traité de référence dans la discipline. La nouvelle édition qui parait toujours sous la direction du professeur Aubier, prend en compte toutes les nouvelles acquisitions depuis 10 ans. L'ouvrage reste divisé en 4 parties : dans la 1ère, les auteurs traitent en 16 chapitres de la physiologie et la physiopathologie de l'appareil respiratoire, cette partie a été enrichie de chapitres sur le développement pulmonaire, l'immunologie respiratoire, le contrôle de la ventilation, l'altitude. Dans la 2ème partie, consacrée aux techniques d'exploration, les auteurs ont largement pris en compte les progrès de l'imagerie et en particulier de la tomodensitométrie et de la TEP. La 3ème partie traite des symptômes et syndromes : toux, dyspnée, expectoration, hémophysie, douleurs thoraciques. La 4ème partie expose, en 60 chapitres, toute la pathologie broncho-pulmonaire depuis la broncho-pneumopathie jusqu'aux manifestations respiratoires des maladies systémiques, en passant par l'asthme, le cancer broncho-pulmonaire, l'embolie pulmonaire, etc.. Dans cette édition, une place toute particulière a été réservée aux pneumopathies émergentes, aux localisations pulmonaires de l'infection par le VIH, à l'HTAP primitive, à la pollution. Dans tous ces chapitres de pathologie, les auteurs abordent successivement les signes cliniques, la stratégie diagnostique aidée des examens paracliniques, les armes thérapeutiques, les prévisions pronostiques. La richesse des illustrations, tableaux, arbres de décision, références bibliographiques fait de cet ouvrage complet, actuel et pratique l'outil indispensable au médecin.

Being obese increases the risk of leukemia, non-Hodgkin lymphoma, multiple myeloma, breast, cervical, colorectal, esophageal, gallbladder, kidney, liver, ovarian, pancreatic, prostate, stomach, and uterine cancers. In addition, some studies show that obesity negatively affects a person's prognosis (chance of recovery). For example, obese men are more likely to be diagnosed with advanced prostate cancer, have a recurrence of prostate cancer, or die of prostate cancer than men who are not obese. This new volume presents significant recent research in the field from around the world.

This definitive reference provides easy access to essential and authoritative clinical guidance on the full range of dermatologic entities encountered in today's practice. It delivers more comprehensive coverage of clinical adult and pediatric dermatology, drug therapy, dermatologic surgery, and pathology than you will find in any other single text. Thousands of helpful illustrations equip you with the visual guidance you need to arrive at confident diagnoses.Discusses pathologic entities in proportion to their incidence, enabling you to focus on the likeliest diagnoses for a given set of symptoms.Includes only the'need-to-know'basic science information and key references, so you have just the right amount of detail on every subject.Presents hundreds of full-color photographs depicting every type of skin disorder, along with a wealth of diagrams that clarify complex concepts and numerous algorithms that expedite decision making. Presents more'high-yield'information in restructured chapters, as well as expanded coverage of rarities - now displayed in table format - without increasing the extent of the book. Includes additional images covering more conditions, for enhanced reference power.

Direct from the Cleveland Clinic Foundation, Endovascular Techniques in the Management of Cerebrovascular Disease is intended for neurologists, neurosurgery fellows-in training, and practicing clinicians with an interest in endovascular procedures. This essential volume:Reviews equipment, devices, and therapeutic agents such as anti-coagulants and

Ein Klassiker aktualisiert! Auch die 8. vollständig neu überarbeitete Auflage liefert unverzichtbares Basiswissen zur Beurteilung pflanzlicher Arzneimittel und beschreibt den Beitrag der Naturstoffforschung zur Entwicklung hochwirksamer Arzneistoffe. Berücksichtigt werden auch die aktuell gebräuchlichen Nahrungsergänzungsmittel und die in Europa verwendeten Arzneidrogen der traditionellen chinesischen Medizin. Die über sieben Auflagen bewährte Grundkonzeption wurde beibehalten: Das Werk informiert umfassend über die Bildung des Naturstoffs in der Pflanze bis zur Herstellung von pflanzlichen Arzneimitteln, deren chemisch-analytische Prüfung, pharmakologische Testung und therapeutische Anwendung. Es liefert Hintergrundwissen über Produkte, die in der Selbstmedikation tagtäglich von Hunderttausenden eingenommen werden. Der neue Hänsel/Sticher ist eine kompakte, aktuelle und wissenschaftlich-kritische Darstellung der Phytochemie, Phytopharmazie, Phytopharmakologie und Phytotherapie für Apotheker, Ärzte und Arzneimittelchemiker sowie ein praxisnahes Lehrbuch der Pharmazeutischen Biologie für Studierende der Pharmazie.