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Pathology of Pet and Aviary Birds A complete reference for veterinary pathologists, residents, and students interested in avian diseases The revised third edition of Pathology of Pet and Aviary Birds delivers a comprehensive reference to gross and microscopic lesions found in birds, as well as the implications of these diseases. This third edition includes improved coverage of normal anatomy and of advanced diagnostic techniques, including special stains, immunohistochemistry, in situ hybridization, and molecular diagnostics. The authors offer an extensive collection of more than 1200 high-quality, full-color images. New chapters cover the postmortem examination; gross and microscopic anatomy; advanced diagnostics; and cytology. Specific chapters address diseases of passerines, Columbidae, and raptors, and other chapters are intuitively organized by body system. The book also provides: A thorough introduction to the preparation and interpretation of cytological samples Comprehensive tables of infectious diseases and published avian primers and IHC markers Practical discussion of diseases of the liver, urinary system, reproductive system, respiratory system, cardiovascular system, nervous system, alimentary system, integument, special senses, and more.High-quality and annotated macroscopic and microscopic images that bolster the text and benefit the reader Pathology of Pet and Aviary Birds is an essential resource for veterinary pathologists and pathology residents, and will also benefit avian practitioners and veterinary students with an interest in diseases of pet birds and birds in avicultural collections. As many diseases in captive birds also manifest in wild birds, the book will appeal to those interested in the diseases and pathology of wild birds.

This book illustrates the role of cellular oxidative stress as one of the most important physiological cornerstones in the evolution of biodiversity. The first part of the book provides the fundamentals to navigate the field and analyse the cross-talk between oxidative status homeostasis and other fundamental organismal functions, such as immunity and stress physiology. The second part of the book argues that oxidative stress underpins the astonishing diversity of adaptations to the environments and the evolution of life-history strategies, from growth to reproduction. Unravelling the (un)expected ways through which the need of regulating the organismal oxidative status has influenced the evolution of life, this book presents a novel integrative way of thinking about how a cellular mechanism has shaped the evolution of life and death.

Sheep Veterinary Practice is the ideal reference for veterinarians in farm animal practice, veterinary and animal science students, agriculturalists and sheep producers. While addressing sheep health, welfare and production matters in Australia, this book covers issues of relevance in any country where sheep are raised.Sheep veterinary specialist Professor Kym Abbott and his co-authors inform the reader of the science underpinning the occurrence of disease syndromes, giving special attention to commonly investigated problems related to nutrition, reproduction and helminthiasis. Other disease conditions of sheep are discussed in subsequent chapters; first on the basis of presenting signs in the case of lameness and sudden death – conditions in which signs can be attributed to disorders of a variety of body systems – and then on a body-systems basis. Following on from Professor Abbott's The Practice of Sheep Veterinary Medicine, a review of the systems and strategies available to improve the welfare of sheep in extensive farming systems is included, as well as discussion of pain relief, analgesia and anaesthesia for sheep.The text is illustrated with over 150 images and photographs, the majority in full colour.

This textbook deals comprehensively with livestock production diseases and their prevention in the major species: ruminants, swine, and poultry. It gives an interdisciplinary view on pathophysiology, prophylaxis, and health management.Livestock breeding and husbandry is often accompanied by a conflict of interest between the animal´s biological requirements and economic producer needs. This conflict is increasingly gaining attention not only by producers, animal scientists, and veterinarians, but also by the public. It creates significant future challenges, which are described and addressed in this book. The main topics covered are: •the use of antimicrobials with emphasis on security and safety for producers/consumers•the impact of locomotion disorders on performance and welfare of farm animals •the interactions of gut microbiome, genetics, climate change, metabolic status and mineral homeostasis with reproduction, performance, animal health and welfare•infectious and respiratory diseases•the raising of neonatesA special section is devoted to behavioural signs indicating an impaired animal welfare. These are the basis for precision livestock farming (PLF) technology and the development of new management concepts. The present work is a valuable resource for veterinarians, students, as well as expert readers from animal and agricultural sciences, food safety and technology. Supplementary videos can be accessed online as well as directly from the print book; simply download the Springer Nature More Media App for free and scan the links with the play button.

This volume 1 of a two-volume work provides an overview of the current state of knowledge on the most common bacterial and fungal diseases in turkeys. Each chapter is dedicated to a specific infectious disease and provides information on pathogenesis, symptoms and therapeutic strategies. The book also includes a general overview on turkey production. The clear and structured layout allows the reader to refer to it quickly. This book is an indispensable guide for veterinarians, researchers and professionals working in turkey production and health.

Horse Pasture Management, Second Edition provides updated coverage on strategies for managing behavior, grouping, environments and feeding needs of grazing horses. Sections cover the structure, function and identification of forages, continuing into nutritional value of pasture plants. Management of soil, the function of a pasture ecosystem and management of plants in a pasture is covered next, followed by forage yield determination, horse grazing behavior, feed choices of horses, management of grazing horses, and how to calculate how many horses should be grazing relative to land size. Advantages of grazing more than one species of animal are described. Management of hay and silage are included since year-round grazing is not possible on many horse farms. Several chapters deal with interactions of a horse farm with the environment, including climate and weather and other living things. The book also covers strategies for managing manure, erosion, and water quality. It is ideal for researchers, scientists and students involved in animal science, specifically equine studies. Agriculturists, equine managers and veterinarians will also find this book useful. - Includes information on environmental best practices, plant and soil assessments, and wildlife concerns - Features a new section on reducing carbon emissions and increasing sustainability on horse farms - Explains pasture-related diseases, weed management and toxic plants to avoid - Recommends relevant published resources and extension programs

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides updated and revised chapters for in-depth discussions of toxicologic pathology for the protection of the environment and food supplies - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

This book provides a comprehensive coverage of all aspects of the welfare of cattle. It starts with a consideration of animal welfare science and its application to the management of cattle and moves through to discussions of the challenges and opportunities for providing good welfare for cattle in farming and husbandry systems across the globe. The first section comprises three chapters that discuss the social, behavioural and physiological methods that can be used to assess welfare in cattle. The second section considers the welfare challenges of beef and dairy cattle in extensive and intensive systems. The third section details welfare challenges such as at slaughter, during handling and in the growing period and details solutions such as the use of sensors and application of animal breeding techniques. The final section addresses welfare challenges and solutions in achieving sustainability, in smallholder farms in Africa and new entrant dairying in Asia and cow shelters in India. This work makes a valuable contribution to the field of animal welfare and modern livestock farming. It is a must-read for researchers and students, veterinarians as well as industry personnel and informed farmers and producers.

This Volume 1 of a two-volume work is the first textbook to offer a practical yet comprehensive approach to clinical ophthalmology in wild and exotic invertebrates, fishes, amphibia, reptiles, and birds. A phylogenetic approach is used to introduce the ecology and importance of vision across all creatures great and small before focusing on both the diverse aspects of comparative anatomy and clinical management of ocular disease from one species group to the next. Edited by three of the most esteemed authorities in exotic animal ophthalmology, this two-volume work is separated into non-mammalian species (Volume 1: Invertebrates, Fishes, Amphibians, Reptiles, and Birds) and Mammals (Volume 2: Mammals). Wild and Exotic Animal Ophthalmology, Volumes 1 and 2 is an essential collection for veterinary ophthalmologists and other veterinary practitioners working with wild and exotic animals.

Food microbiology is a crucial area of study that delves into the intricate world of microorganisms present in food and those utilized in food production processes. This insightful book offers a comprehensive exploration of food microbiology, focusing on various aspects such as food poisoning, food spoilage, food preservation, and food legislation. Readers will gain valuable insights into the general biology of microorganisms found in foods, including their growth characteristics, identification, and pathogenesis. From understanding the sources of microorganisms in foods to examining the intrinsic and extrinsic factors affecting microbial growth, the book provides a thorough overview of the field. It discusses common indicators of food safety such as Escherichia coli, Enterococcus spp., and Staphylococcus aureus, and explores the diverse effects of microorganisms on food products, ranging from spoilage to food poisoning. With topics covering ancient health foods, bacterial interactions in food, food proteins, flavonoid intake, microbial quality management, and more, this book offers in-depth information about the applications of microbiology in various industries and studies. It also delves into areas such as microbial quality of milk, food-producing animals, zoonotic bacteria, ontology, and microorganism-produced enzymes, providing readers with a comprehensive understanding of the field. Whether you're a student, researcher, or professional in the food industry, this book serves as an invaluable resource for gaining knowledge about the uses of microbiology and understanding the latest concepts and developments in food microbiology.

A comprehensive and authoritative guide to neurologic disease in large domestic animals, world-wide. The newly revised Third Edition of Large Animal Neurology delivers a practical and complete reference for veterinarians, veterinary trainees and scientists dealing with large animal neurology. The book is vividly illustrated in full colour and contains many clinical photographs and detailed line drawings to highlight the concepts discussed within. Organised into three parts, Large Animal Neurology offers practitioners and students straightforward guides on how to perform neurologic examinations for domestic large animal species, including neonates. It also discusses the presenting clinical syndromes caused by common nervous system diseases, as well as giving details of the specific neurologic diseases of large domestic animals. The book includes: A thorough introduction to the evaluation of large animal neurologic patients, including discussions of neuroanatomy, neurologic evaluation, ancillary diagnostic aids, and the important pathologic responses of the nervous system Comprehensive exploration of 26 presenting clinical problems, including behaviour disorders, seizures, epilepsy, sleep disorders, blindness, strabismus, monoplegia, wobblers, tetraplegia, pruritus and cauda equina syndrome Detailed coverage of the specific diseases, including those of genetic, infectious, nutritional, toxic and metabolic cause, and the many diseases with multifactorial and with unknown cause Perfect for all equine and farm animal veterinarians, veterinary neurologists, as well as trainees in the field, Large Animal Neurology, Third Edition is also an ideal resource for undergraduate veterinary students, animal pathologists, and neuroscience researchers.

Functional genomics, a field of molecular biology, provides a comprehensive understanding of gene functions, interactions, and protein functions on a universal level. Unlike classical molecular biology techniques, functional genomics employs genome-wide approaches to describe the functions and interactions of genes and proteins. This book delves into key aspects of functional genomics, ranging from evaluating genetic codes to understanding proteomic ramifications. It explores diverse topics such as genomic abnormalities, proteomic pathways, expression alterations, peptidase screening, genomic instability, and functional neurogenomics. With a focus on applications in biomedicine, agro-food technologies, and zoo techniques, the book highlights primary problems and recent advances in science and technology in the field of genomics medicine. By emphasizing the relation of these topics to functional genomics, the book serves as a comprehensive resource guide for both graduate and postgraduate students, contributing to the growth and advancement of the discipline. Whether delving into genomic instability or exploring proteomic pathways, this book offers valuable insights into the multifaceted world of functional genomics and its applications in diverse domains

Our knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.

This volume explores recent research trends and achievements in environmental pollution remediation (e.g. water, air, soil), and compiles critical and constructive papers and reviews with a focus on advances in bioremediation and green technology solutions for waste minimization, waste management and pollution control. The book is timely, as the need for researchers and engineers to develop sustainable and green eco-friendly remediation technologies is increasing with a growing global population, stressed agricultural systems, and an environment impacted by climate change. A key focus of the book is on the efficient use of agricultural waste residues as viable substrates for creating materials for environmental clean-up, and the possible conversion of these pollutants to sustainable bioresources. The volume will be of interest to sustainability researchers, environmental engineers, industry managers and agricultural scientists.

••Selected for Doody's Core Titles® 2024 in Veterinary Medicine•• Get practical answers from the only guide on the care of sheep, goats, and cervids! Authoritative yet easy to read, Sheep, Goat and Cervid Medicine, 3rd Edition covers all the latest advances in the field, including diseases and medical treatment, surgery, pain management, theriogenology, and nutrition. Clear instructions and hundreds of full-color photographs guide you step by step through common procedures including restraint for examination, administration of drugs, blood collection, and grooming. New to this edition is coverage of deer and elk medicine, reflecting the growing interest in these ruminants. Written by an expert team led by Dr. D.G. Pugh, this comprehensive reference is ideal for veterinarians and also for owners of sheep and goats. - Clear writing style and consistent organization makes the book easy to understand and use, with disease chapters including pathogenesis, clinical signs, diagnosis, treatment, and prevention. - Coverage of both surgery and medicine in each body systems chapter makes it easier to choose between treatment options for specific disorders. - Superbly illustrated surgical procedures clearly demonstrate the steps to follow in performing medical and reproductive surgery. - Diverse, expert contributors include the most experienced authorities, each providing current information on the care of valuable breeding stock as well as pets. - Useful appendixes, now including veterinary feed directives, offer convenient access to information on drugs and drug dosages, fluid therapy, and normal values and conversions. - Consistent, logical format in each body systems chapter makes information easy to find by beginning with physical examination and diagnostic procedures, followed by discussions of common diseases that involve the system. - Comprehensive Feeding and Nutrition chapter covers diet evaluation, method of balancing rations, total parenteral nutrition, and examples of nutritious diets. - Explanation of the differences in normal behavior between sheep and goats shows how they are not the same, and require different methods of treatment. - NEW! Coverage of cervids has been added to chapters throughout the book, reflecting the growing popularity of deer and elk. - NEW! Thorough content updates are made throughout the book and reflect the latest research evidence. - NEW! 170 new clinical photos have been added. - NEW! Anesthesia and Pain Management chapter includes a new section on pain management strategies, reflecting the emphasis on controlling pain in small ruminants. - NEW! Expert Consult website offers an online version of the book, making it easy to search the entire book electronically. - NEW! Two new authors are respected and well-known veterinary medicine experts and educators: Dr. Misty Edmondson and Dr. Thomas Passler.

••Selected for Doody's Core Titles® 2024 with'Essential Purchase'designation in Veterinary Medicine•• Utilize a problem-oriented approach to the diagnosis of diseases of horses, cattle, sheep, and goats. Large Animal Internal Medicine, 6th Edition covers the diagnosis and management of disease in both ruminant and equine internal medicine. As the first veterinary internal medicine text to use a problem-based approach, it offers discussions of over 150 clinical signs and manifestations, as well as comprehensive coverage of laboratory and diagnostic testing. New to this edition is a versatile online reference platform and coverage of conditions that exist in Europe, Central and South America, Australia, and New Zealand. In addition, thoroughly revised and updated content includes new vaccines and vaccination protocols; the most current laboratories for DNA, genetic, and PCR testing; and colostrum supplements and replacers. It's everything you need to stay up to date with the latest information on preventing and treating disease in large animals.Discussions of over 150 clinical signs or manifestations of disease provide you with a problem-based approach to diagnosis based on what you've observed and what laboratory tests reveal.Causes of Presenting Signs boxes offer quick access to the common, less common, and uncommon diseases associated with manifestations or signs of disease.Causes of Abnormal Laboratory Values boxes highlight the possible interpretations of abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. More than 200 expert authors contribute information in their areas of expertise for the most current, authoritative information on each topic. NEW! Expert Consult platform provides a versatile digital resource including bonus content, useful references, and videos to meet the needs of practicing equine and large animal veterinarians. NEW! Global conditions of importance are covered, including those previously not discussed, that exist in Europe, Central and South America, Australia, and New Zealand. NEW! Coverage of emerging and re-emerging diseases includes the new pathogen discovery. NEW! Assessment of vaccination status and susceptibility to infection discusses how antibody titers can predict protection for some pathogens. NEW! Description of epigenetics and metagenomics provides detailed coverage of these emerging areas of interest. NEW! Table of zoonoses obtained from large animals includes symptoms and disinfection needs. NEW! Videos demonstrate how to perform ultrasound imaging on an equine and cow abdomen clearly showing where to position the probe, and what depth to use for scans of the kidneys, liver, and bowel. NEW! Coverage of genetic disorders, Hydrocephalus in Fresians and Pulmonary hypoplasia with Anasarca in Dexter cattle help you to treat these disorders. NEW! Extensively updated content clarifies the latest research and clinical findings on the West Nile Virus, therapeutic drug monitoring, muscle disorders, GI microbiota, the genetic basis for Immune-mediated myositis in Quarter Horses, discoveries in antimicrobial drugs, anthelmintic, and vaccines, and more!

Probiotics are live microbial feed supplements that beneficially affect the host by improving its intestinal microbial balance. The microorganisms come from a whole range of defined strains of probiotics belonging to the groups of lactic acid bacteria, Bacillus spores, and yeasts. Research in nutritional physiology demonstrates the critical importance of a balanced gut microflorain in animal and human physiology. The probiotic concept is concerned with optimizing nutritional intake and digestion by promoting the gut flora perspective. Probiotics act by reducing the feed conversion, resulting in an increase of the daily live weight gain. The improvement of the growth of an animal is achieved through a natural, physiological way: improving digestion by balancing the gut flora, helping the animal to fulfill its genetic potential. This book discusses probiotics'mode of action and probiotics'practical application in poultry production, while explaining the use of probiotics in preventing and fighting poultry diseases, such as Salmonellosis, Necrotic Enteritis, Coccidiosis, bacterial lameness, etc. It will be essential reading for a wide group of readers, including university staff, feed mill companies, poultry producers, veterinarians, and researchers in the field. [Subject: Animal Science, Veterinary Science, Poultry Farming, Agriculture]

This book gathers a selection of original articles and critical reviews presented at the 21st International Taurine Meeting, held in Shenyang, China in May 2018, which discussed and disseminated the latest findings on taurine, especially in human life. The book is divided into eight parts, which respectively address: Taurine and Metabolism, Taurine and Nutrition, Taurine and Organ Dysfunction, Taurine and Heart Health, Taurine and Anti-cancer, Taurine and Anti-oxidation / Anti-microbial, Taurine and Neuroprotection, and Taurine and Anti-inflammatory. These latest discoveries concerning the functions and advantageous effects of taurine on the health of various human body systems will not only advance the treatment of human diseases and the quality of human life, but also promote further research into the applications of taurine in human health.

Nutrition is the key driver of animal health, welfare and production. In agriculture, nutrition is crucial to meet increasing global demands for animal protein and consumer demands for cheaper meat, milk and eggs and higher standards of animal welfare. For companion animals, good nutrition is essential for quality and length of life. Animal Nutrition examines the science behind the nutrition and feeding of the major domesticated animal species: sheep, beef cattle, dairy cattle, deer, goats, pigs, poultry, camelids, horses, dogs and cats. It includes introductory chapters on digestion and feeding standards, followed by chapters on each animal, containing information on digestive anatomy and physiology, evidence-based nutrition and feeding requirements, and common nutritional and metabolic diseases. Clear diagrams, tables and breakout boxes make this text readily understandable and it will be of value to tertiary students and to practising veterinarians, livestock consultants, producers and nutritionists.

This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.

Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of'Best Practice'approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. - Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups - Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status - Informs laboratories looking for third party providers of specialist investigations - Provides an essential overview of reference ranges for each vitamin

Horse Pasture Management begins with coverage of the structure, function and nutritional value of plants, continuing into identification of pasture plants. Management of soil and plants in a pasture is covered next, followed by horse grazing behavior, feed choices of horses, management of grazing horses, and how to calculate how many horses should be grazing relative to land size. Management of hay and silage are included, since year-round grazing is not possible on many horse farms. A number of chapters deal with interactions of a horse farm with the environment and other living things. As an aid in good pasture management, one chapter explains construction and use of fencing and watering systems. Contributions are rounded out with a chapter explaining how the University of Kentucky helps horse farm managers develop their pasture management programs. - The purpose of the book is to help people provide a better life for horses - Provides the basic principles of pasture management for those involved in equine-related fields and study - Covers a variety of strategies for managing the behavior, grouping, environmental, and feeding needs of grazing horses to ensure high levels of welfare and health - Includes information on environmental best practices, plant and soil assessment, and wildlife concerns - Explains pasture-related diseases and toxic plants to be avoided - Includes links to useful resources and existing extension programs

Lignin - Trends and Applications consists of 11 chapters related to the lignin structure, modification, depolymerization, degradation process, computational modeling, and applications. This is a useful book for readers from diverse areas, such as physics, chemistry, biology, materials science, and engineering. It is expected that this book may expand the reader's knowledge about this complex natural polymer.

This volume provides an overview of microbial toxins from diverse bacterial and fungal origins. These molecules, produced by various species and consisting of protein or small organic molecules, can play a pivotal role in pathogenesis of plants, animals, and humans that in turn can lead to the survival/dissemination of the host microbe. Many of these microbes, due to their toxins, impact our society from a health and economic perspective. In particular, this volume address the diverse niches of these organisms focused upon their associated toxins. The structures, functions, and genetics of toxins will be addressed. Besides the ill-effects elicited by these toxins, it must be noted that there is immense potential for turning some of these harmful molecules into useful tools as specific probes (of receptors), novel drugs or drug-conjugates for the treatment of various diseases, and immunomodulating agents for targeted vaccine delivery for research and unique medicines. Recent progress inbacterial genome mapping and establishment of three-dimensional crystal structures of several bacterial toxins provides a deeper knowledge and greater understanding of structure-function relationships. Moreover, the emergence of some bacteria (i.e., Bacillus anthracis, Burkholderia pseudomallei, Staphylococcus aureus), and their toxins, as biological weapons also necessitates a thorough understanding of these agents, their pathophysiology, and development of countermeasures. This volume will also be a common resource for researchers interested in many other medically-relevant microorganisms, and their toxins, that include Clostridium botulinum, C. difficile, C. perfringens, C. tetani, Escherichia coli, Helicobacter pylori, and Listeria monocytogenes. Recent studies have correlated the effect of global warming and climate change as a trigger for natural disasters and impact on human health via emergence of various vector-borne and infectious diseasescaused by toxin-producing microbes. The 2003 Institute of Medicine (IOM) report, “Microbial Threats to Health,” identified the influence of changing ecosystem on the emergence and spread of infectious diseases and economic development of specific regions of the world. This current handbook is a major reference work on microbial toxins written by a panel of International experts and organized into 24 chapters.

This proceedings volume contains a selection of invited and contributed papers of the 10th International Workshop on Sulfur Metabolism in Plants, which was held in Goslar, Germany September 1-4, 2015. The focus of this workshop was on the fundamental, environmental and agricultural aspects of sulfur in plants, and presents an overview of the progress in the research developments in this field in the 28 years since the first of these workshops. The volume covers various aspects of the regulation of the uptake and assimilation of sulfate in plants from a molecular to a whole plant level with an emphasis on the significance of sulfur metabolism in plant responses to stress and in food security.

This issue, edited by Dr. Kevin Washburn, focuses on Food Animal Neurology. Article topics include: Neurological examination of the ruminant; Diagnostics and ancillary tests of neurologic dysfunction in the ruminant; Localization of neurologic lesions in ruminants; Cerebral disorders of calves; Cerebral disorders of the adult ruminant; Cerebellar disorders of ruminants; Brain stem and cranial nerve disorders of ruminants; Spinal cord and peripheral nerve abnormalities of the ruminant; and Toxicoses of the ruminant nervous system.

This book explores the current trends and challenges of sustainable goat meat and milk production in different global contexts, providing valuable insights into this industry in adverse environments like mountain, semiarid and arid regions. It also includes contributions from international experts discussing goat reproduction, genetic diversity and improvement, as well topics such as animal health, welfare, socioeconomic aspects, and many other issues regarding the environmentally friendly and economically viable exploitation of goats. This is a highly informative book providing scientific insight for readers with an interest in sustainable agriculture and socio-economic aspects, as well as goat breed conservation, genetic diversity, and veterinary care. These subjects are complemented in a second volume providing a detailed description of more than 40 indigenous goat breeds and several ecotypes found in Asia, Africa, Europe, and America.

This first volume of the Trilogy of Traditional Foods, part of the ISEKI Food Series, covers general and consumer aspects of traditional foods. It offers numerous recipes of traditional foods from across the world, with some chapters providing detailed descriptions on how to mix, cook, bake or store a particular food item in order to produce the desired effect.Traditional Foods; General and Consumer Aspects is divided into six sections. The first section focuses on general aspects of traditional foods and covers the perception of traditional foods and some general descriptions of traditional foods in different countries. This is followed by sections on Traditional Dairy Products, Traditional Cereal Based Products, Traditional Meat and Fish Products, Traditional Beverages and Traditional Deserts, Side Dishes and Oil products from various countries.The international List of Contributors, which includes authors fromChina, Bulgaria, Portugal, France, Norway, Romania, Slovakia, and Brazil, to name a few, shows its truly international perspective. The volume caters to the practicing food professional as well as the interested reader.

This volume focuses on those instances when benign and even beneficial relationships between microbes and their hosts opportunistically change and become detrimental toward the host. It examines the triggering events which can factor into these changes, such as reduction in the host's capacity for mounting an effective defensive response due to nutritional deprivation, coinfections and seemingly subtle environmental influences like the amounts of sunlight, temperature, and either water or air quality. The effects of environmental changes can be compounded when they necessitate a physical relocation of species, in turn changing the probability of encounter between microbe and host. The change also can result when pathogens, including virus species, either have modified the opportunist or attacked the host's protective natural microflora. The authors discuss these opportunistic interactions and assess their outcomes in both aquatic as well as terrestrial ecosystems, highlighting the impact on plant, invertebrate and vertebrate hosts.

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

This brand-new, full-color reference is a foundational text for veterinarians and veterinary students learning about companion exotic animal diseases. Organized by body system, Current Therapy in Exotic Pet Practice walks students through the most relevant information concerning the diagnosis and treatment of exotic animals — including the most relevant information on anatomy, physical examination, diagnostic testing, disease conditions, therapeutics, epidemiology of diseases, and zoonoses. Topics such as captive care, current standards of care for all exotic species, veterinary clinical epidemiology, and the effective prevention and management of infectious diseases are also included. - Expert guidance on treating various disease conditions provides authoritative support for veterinarians who are less experienced in companion exotic pet care. - Renowned authors and editors carefully selected topics of real clinical importance. - Detailed coverage on how to identify and treat diseases (from common to rare) helps alleviate apprehension a veterinarian may feel when treating an unfamiliar species. - Includes the latest information from the current scientific literature and addresses hot topics associated with treating companion exotic animals today. - Vivid full-color images demonstrate the unique anatomic and medical features of each group of animals covered.

This volume summarizes our current knowledge on different biomass-converting enzymes and their potential use in converting biomass into simple sugar to generate bioenergy and other value added co-/by products. It consists of 13 chapters and is divided into three parts: cellulases; hemicellulases; and lignocellulose oxidoreductases. Written by international experts, the contributions offer clear and concise descriptions of both standard and new technologies. It is an invaluable reference resource for undergraduates, post-graduates, researchers and practitioners in the field of microbial enzymes for biofuel and biorefinery applications.

This issue of Veterinary Clinics of North America: Food Animal Practice is guest edited by Dr. Mike Apley on the topic of Bovine Therapeutics. Article subject areas include: Interpretation of bovine susceptibility, Pain control in cattle, Mastitis, Bovine respiratory disease, Enteric disease, Central nervous system disease, Pinkeye, Genitourinary Problems, Musculoskeletal Problems, and the use of metrics to evaluate therapeutic evidence.

Large Animal Internal Medicine, 4th Edition features a problem-based approach with discussions of over 150 clinical signs. This is the first internal medicine reference that enables you to efficiently diagnose horses, cattle, sheep, and goats based on clinical observation and laboratory and diagnostic testing. With this user-friendly format, you can find essential information about specific diseases and reach a diagnosis by simply identifying the signs. - A unique problem-based approach with discussions of over 150 clinical signs and manifestations helps you quickly reach a diagnosis based on observations and laboratory tests. - Causes of Presenting Signs boxes provide easy access to complete lists of common, less common, and uncommon diseases associated with manifestations or signs of disease. - Complete lists of diseases associated with a given lab abnormality in Causes of Abnormal Laboratory Values boxes help you easily interpret abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. - An expert team of over 180 authors contributing information in their areas of expertise ensures you are using the most accurate and up-to-date information available. - Color plates accompanying Diseases of the Eye and Diseases of the Alimentary Tract enable you to visually recognize the clinical appearance of ophthalmologic conditions and alimentary tract disorders for quick and easy diagnosis and treatment. - NEW! Extensively updated content from expert authors clarifies the latest research and clinical findings on pain, the nervous system, toxicology, BVD, malignant catarrhal fever, bluetongue, and strong ions. - NEW! Vaccines and vaccination protocols keep you up-to-date with the information you need to prevent newly emerging diseases in large animals. - NEW! Expanded coverage of the veterinarian's role in animal welfare; equine abdominal ultrasound; DNA, genetic, and PCR testing; and colostrum supplements and replacers supplies you with the most current large animal internal medicine information. - NEW! Current information on foreign animal diseases dangerous to large animals in the US, including coverage of rinderpest, keeps you aware of diseases that can be transmitted from other countries.

This book discusses the commercialization of biofuels and the Brazilian government policies for the promotion of renewable energy program in Brazil, which could be a learning module for several countries for implementing biofuels policy to improve their socioeconomic status and make them energy independent.Researchers in academia and industries, policy makers, and economic analysts will be assisted by important source of information in their ongoing research and future perspectives.This book will benefit graduate and postgraduate students of chemical and biochemical engineering, forestry, microbiology, biochemistry, biotechnology, applied chemistry, environmental science, sustainable energy, and biotech business disciplines by signifying the applied aspects of bioenergy production from various natural sources and their implications. Graduate and postgraduate students as well as postdoctoral researchers will find clear concepts of feedstock analysis, feedstock degradation, microbial fermentation, genetic engineering, renewable energy generation and storage, climate changes, and techno-economic analysis of biofuels production technologies.

Beef Cattle Production and Trade covers all aspects of the beef industry from paddock to plate. It is an international text with an emphasis on Australian beef production, written by experts in the field. The book begins with an overview of the historical evolution of world beef consumption and introductory chapters on carcass and meat quality, market preparation and world beef production. North America, Brazil, China, South-East Asia and Japan are discussed in separate chapters, followed by Australian beef production, including feed lotting and live export. The remaining chapters summarise R&D, emphasising the Australian experience, and look at different production systems and aspects of animal husbandry such as health, reproduction, grazing, feeding and finishing, genetics and breeding, production efficiency, environmental management and business management. The final chapter examines various case studies in northern and southern Australia, covering feed demand and supply, supplements, pasture management, heifer and weaner management, and management of internal and external parasites.

Wheat and Rice in Disease Prevention and Health reviews the wide range of studies focusing on the health benefits and disease prevention associated with the consumption of wheat and rice, the two most widely consumed whole grains. This book provides researchers, clinicians, and students with a comprehensive, definitive, and up-to-date compendium on the diverse basic and translational aspects of whole grain consumption and its protective effects across human health and disease. It serves as both a resource for current researchers as well as a guide to assist those in related disciplines to enter the realm of whole grain and nutrition research. Overall, studies have shown that a decrease in the amount of whole grains in the modern diet is related to a corresponding increase in health problems that are attributed to this all-too-common dietary imbalance. The resulting health issues associated with an over-processed diet, which provides inadequate levels of nutrients from whole grains, may include obesity, diabetes, high blood lipids, chronic inflammatory states, and an excess of oxidative stress. Strength and endurance may also suffer as a result of these nutrient deficiencies, followed by declines in energy and immunity. - Saves researchers and clinicians time in quickly accessing the latest details on a broad range of nutritional and epidemiological issues - Provides a common language for nutritionists, nutrition researchers, epidemiologists, and dietitians to discuss how the action of wheat and rice protect against disease and modify human health - Preclinical, clinical, and population studies help nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations

Rapid growth of population is putting excessive strain on natural resources while the technological advances are causing unprecedented release of xenobiotics in the environment. Intensive agricultural and animal husbandry practices also make significant contribution to the pollution, jeopardizing the safety of environmental resources and the food chain. The natural ecosystem is becoming hostile day by day and man and animals are confronted with similar types of health risk. It is quite a challenge to the scientists to build a sustainable environment without halting the process of industrial and economic growth. In this book, distinguished scientists from the top institutions have provided elaborate environmental risk analysis and futuristic mitigation plans to safeguard human and animal health. The book is an unmatched reference resource not only for the students, teachers and researchers of public health and animal health disciplines but also for the health planners and policymakers.

Allelopathy is an ecological phenomenon by which plants release organic chemicals (allelochemicals) into the environment influencing the growth and survival of other organisms. In this book, leading scientists in the field synthesize latest developments in allelopathy research with a special emphasis on its application in sustainable agriculture. The following topics are highlighted: Ecological implications, such as the role of allelopathy during the invasion of alien plant species; regional experiences with the application of allelopathy in agricultural systems and pest management; the use of microscopy for modeling allelopathy; allelopathy and abiotic stress tolerance; host allelopathy and arbuscular mycorrhizal fungi; allelopathic interaction with plant nutrition; and the molecular mechanisms of allelopathy. This book is an invaluable source of information for scientists, teachers and advanced students in the fields of plant physiology, agriculture, ecology, environmental sciences, and molecular biology.

Toxic Plants of North America, Second Edition is an up-to-date, comprehensive reference for both wild and cultivated toxic plants on the North American continent. In addition to compiling and presenting information about the toxicology and classification of these plants published in the years since the appearance of the first edition, this edition significantly expands coverage of human and wildlife—both free-roaming and captive—intoxications and the roles of secondary compounds and fungal endophytes in plant intoxications. More than 2,700 new literature citations document identification of previously unknown toxicants, mechanisms of intoxication, additional reports of intoxication problems, and significant changes in the classification of plant families and genera and associated changes in plant nomenclature. Toxic Plants of North America, Second Edition is a comprehensive, essential resource for veterinarians, toxicologists, agricultural extension agents, animal scientists, and poison control professionals.

Environmental stress is one of the most significant factors affecting livestock performance and health, and it is only expected to increase with effects of global warming. Environmental Physiology of Livestock brings together the latest research on environmental physiology, summarizing progress in the field and providing directions for future research. Recent developments in estimating heat stress loads are discussed, as well as key studies in metabolism, reproduction, and genetic expressions. Environmental Physiology of Livestock begins with a survey of current heat indexing tools, highlighting recent discoveries in animal physiology, changes in productivity levels, and new technologies available to better estimate stress response. Using this synopsis as a point of orientation, later chapters hone in on major effects of heat stress, including changing metabolic pathways and nutrient requirements, endocrine regulation of acclimation to environmental stress, and reduced reproductive performance. The text concludes with a thorough discussion of environmental effects on gene expressions, providing important insight for future breeding practices. Environmental Physiology of Livestock is a globally contributed volume and a key resource for animal science researchers, geneticists, and breeders.

Veterinary Toxicology, 2nd Edition, is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This new edition brings together insights from qualified and well-experienced authorities across all areas of veterinary toxicology to provide an authoritative and in-depth look at all facets of veterinary toxicology, including target organ toxicity, melamine and cyanuric acid, toxicogenomics, chemical terrorism and nanoparticles. While most comparable texts are primarily directed toward the field of human toxicology, this is the one text needed to thoroughly prepare future veterinarians on the newest approaches for diagnosing poisoning cases in all animals from chemicals and plants of a diverse nature as a result of inadvertent, accidental, or malicious intents. It is thoroughly updated with new chapters and the latest coverage of topics not tackled in any previous books such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. There are also expanded discussions on international topics such as epidemiology of animal poisonings and regulatory guidelines and poisonous plants in Europe. Problem solving strategies are offered for treatment. This volume will be of interest to practitioners, professors and students of veterinary medicine and veterinary toxicology, poison control centers, marine biologists, environmentalists and animal scientists. - Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries - New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology - Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe - Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology - Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Authoritative yet easy to read, Sheep and Goat Medicine, 2nd Edition covers all the latest advances in sheep and goat medicine, including medical treatment, surgery, theriogenology, and nutrition. Full-color photographs and clear instructions provide the answers you need, guiding you through common procedures and techniques such as restraint for examination, administration of drugs, blood collection, and grooming; these descriptions are often accompanied by explanatory diagrams and charts. With diseases, surgeries, and treatments organized by body system, information is always easy to find. New to this edition are chapters on parasite control, nutritional requirements, and performing a necropsy. Developed by Dr. D.G. Pugh, a world-renowned expert on the medical care of sheep and goats, this reference is unmatched for its comprehensive coverage of herd health, physical examination, anesthesia, and multisystem diseases. - Clear writing style makes the book useful and easy to understand, even for sheep and/or goat owners who are not veterinarians. - Both surgery and medicine are covered in each body systems chapter, so it's easier to choose between treatment options for specific disorders. - Superbly illustrated surgical procedures clearly demonstrate the steps to follow in performing surgical procedures. - An explanation of the differences in normal behavior between sheep and goats shows how they are not the same, and require different methods of treatment. - A consistent, logical format in each body systems chapter makes information easy to find by beginning with physical examination and diagnostic procedures, followed by discussions of common diseases that involve the system. - Consistent headings include pathogenesis, clinical signs, diagnosis, treatment, and prevention. - A comprehensive nutrition chapter covers diet evaluation, method of balancing rations, total parenteral nutrition, and examples of nutritious diets. - Practical formulas are included for making sodium sulfite for testing passive transfer, and Sheather's solution for fecal flotation. - Useful appendixes summarize essential information on drugs and drug dosages, fluid therapy, and normal values and conversions. - A diverse, authoritative panel of contributors provides current information on the care of valuable breeding stock as well as pets. - Full-color photographs and graphics accurately depict conditions and procedures. - New Fluid Therapy and Nutritional Support chapter covers emergency and critical care essential to the care of sheep and goats. - New Gastrointestinal Parasitism chapter covers treatments for parasites, key to the successful management of all flocks. - New Necropsy chapter helps you prevent disease outbreaks in a flock by determining the cause of death.

Guest Editor Gary Osweiler presents a comprehensive look at ruminant toxicology. Topics will include biofuels co-products tolerance and toxicology for ruminants, diagnostic toxicology for ruminants, metal/mineral poisoning and interactions, reproductive toxicants in forage and grain crops, ruminant mycotoxicoses, antidotes and therapy for ruminant toxicants, western plant hazardous to ruminants, southeastern toxic plants affecting ruminants, northeastern plants toxic to ruminants, industrial and commercial products affecting ruminants, water quality and ruminant health and productivity,,and much more!

Bioethanol is one of the main biofuels currently used as a petroleum-substitute in transport applications. However, conflicts over food supply and land use have made its production and utilisation a controversial topic. Second generation bioalcohol production technology, based on (bio)chemical conversion of non-food lignocellulose, offers potential advantages over existing, energy-intensive bioethanol production processes. Food vs. fuel pressures may be reduced by utilising a wider range of lignocellulosic biomass feedstocks, including energy crops, cellulosic residues, and, particularly, wastes.Bioalcohol production covers the process engineering, technology, modelling and integration of the entire production chain for second generation bioalcohol production from lignocellulosic biomass. Primarily reviewing bioethanol production, the book's coverage extends to the production of longer-chain bioalcohols which will be elemental to the future of the industry.Part one reviews the key features and processes involved in the pretreatment and fractionation of lignocellulosic biomass for bioalcohol production, including hydrothermal and thermochemical pretreatment, and fractionation to separate out valuable process feedstocks. Part two covers the hydrolysis (saccharification) processes applicable to pretreated feedstocks. This includes both acid and enzymatic approaches and also importantly covers the development of particular enzymes to improve this conversion step. This coverage is extended in Part three, with chapters reviewing integrated hydrolysis and fermentation processes, and fermentation and co-fermentation challenges of lignocellulose-derived sugars, as well as separation and purification processes for bioalcohol extraction.Part four examines the analysis, monitoring and modelling approaches relating to process and quality control in the pretreatment, hydrolysis and fermentation steps of lignocellulose-to-bioalcohol production. Finally, Part five discusses the life-cycle assessment of lignocellulose-to-bioalcohol production, as well as the production of valuable chemicals and longer-chain alcohols from lignocellulosic biomass.With its distinguished international team of contributors, Bioalcohol production is a standard reference for fuel engineers, industrial chemists and biochemists, plant scientists and researchers in this area. - Provides an overview of the life-cycle assessment of lignocelluloses-to-bioalcohol production - Reviews the key features and processes involved in the pre-treatment and fractionation of lignocellulosic biomass for bioalcohol production - Examines the analysis, monitoring and modelling approaches relating to process and quality control in pre-treatment, hydrolysis and fermentation

Kein psychologischer Einfluss auf den Körper kann größer sein als derjenige, der den Tod herbeiführt. Ausgelöst durch psychische Beeinflussung und vollzogen durch die eigene Vorstellungskraft: Der psychogene Tod ist das dramatischste Beispiel für die Macht der inneren Bilderwelt und der Sprache über das menschliche Leben. Gary Bruno Schmid – theoretischer Physiker, Psychologe und Psychotherapeut – hat die Fakten und Anekdoten über den psychogenen Tod gesammelt, kritisch bewertet und mit neuen Daten zu den wissenschaftlichen Grundlagen unterlegt. Das Spektrum reicht vom Voodoo- und Tabutod über den Heimweh-Tod bis zur tödlichen Katatonie. Erstmals werden damit die Hintergründe erhellt, wie Menschen ohne nachweisbare physische Ursachen durch den Austausch von Information sterben. Der Autor zeigt die Macht der eigenen Vorstellungskraft auf. Das Buch wendet sich insbesondere an Psychologen, Psychotherapeuten, Psychiater, Ärzte und Ethnologen, ist aber auch für Laien verständlich geschrieben.

Bottom Line Information to Effectively Diagnose DisordersThe diagnosis, management, and clinical testing associated with old, traditional, and new endocrine disorders have seen numerous advances during the past 10 years since the publication of the previous edition of this bestselling resource. Updating its classic predecessor in content and format

Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. - New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology - Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe - Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology - Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

The eBook version of this title gives you access to the complete book content electronically•. Evolve eBooks allows you to quickly search the entire book, make notes, add highlights, and study more efficiently. Buying other Evolve eBooks titles makes your learning experience even better: all of the eBooks will work together on your electronic'bookshelf', so that you can search across your entire library of Veterinary Medicine eBooks. •Please note that this version is the eBook only and does not include the printed textbook. Alternatively, you can buy the Text and Evolve eBooks Package (which gives you the printed book plus the eBook). Please scroll down to our Related Titles section to find this title. The tenth edition of this well-established text has been reviewed and extensively revised, and new diseases added, based on literature published worldwide since 2000. It is directed primarily at students of veterinary medicine and at practicing veterinarians and field workers. It has come to be extensively used as a reference by veterinarians in large and mixed animal practice around the world: it has attained international relevance, recognition and acceptance with several translations. The book is divided into a General Medicine section (15 chapters) which describes clinical examination and the manifestation of disease in organ systems and a Special Medicine section (21 chapters) which describes the specific diseases of the large animal species, their causes, epidemiology, pathophysiology, clinical and pathological manifestations, treatment, control and prevention, and zoonotic risk. In the General Medicine chapters Dr Peter Constable, an authority in agricultural internal medicine, is a new major author and has reviewed and revised major parts of discussions on systemic disorders and the chapters on diseases of the cardiovascular system, the urinary system, the nervous system, and the chapter on mastitis. Other Chapters in the General Medicine chapters have been revised and the sections on gastrointestinal disease of horses and the chapters on respiratory system and hemopoietic and lymphatic systemes have been totally re-written by Dr Hinchcliff. The specific diseases of large animal species have been updated sine the last edition by all authors but of particular note in this Special Medicine section is the contributions of three new contributing authors. Dr Stan Done, an internationally recognized authority on diseases of pigs, has taken responsibility for the diseases of this species throughout the text, and adds a European input to the text. Dr Gary Osweiler, a well recognised clinical diagnostic toxicologist, has taken the responsibility for the revision of the topics on toxicological diseases and Dr Douglas Colwell, the diseases associated with arthropod parasites. In keeping with current diseases and their importance there is a new chapter on diseases associated with prions. This section has been completely revised and descriptions of many of the diseases of current importance completely re-written. There is a new chapter on diseases associated with prions. - Includes important information essential to any large-animal veterinarian, especially those working with horses, cattle, sheep, pigs, or goats. - User-friendly format allows the reader to quickly absorb key information. - Quick review/synopsis sections for complex diseases make important information easy to find. - Features content on major diseases of all countries, including foreign animal and emerging diseases.