69 results on '"JAMES, MICHAEL N. G."'
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2. Overcoming the Unfavourable Entropic Contribution of Ligand Binding with a Macrocyclic Inhibitor Bound to Penicillopepsin
3. Crystal Structure of Human Pepsinogen A
4. Crystallographic Studies of an Activation Intermediate of Human Gastricsin
5. Shiga Toxin
6. Why Does Pepsin Have a Negative Charge at Very Low pH? An Analysis of Conserved Charged Residues in Aspartic Proteinases
7. Consequences of Intramolecular Ionic Interactions for the Activation Rate of Human Pepsinogens A and C as Revealed by Molecular Modelling
8. Penicillopepsin: 2.8 a Structure, Active Site Conformation and Mechanistic Implications
9. Substrate Specificity and Molecular Modelling of Aspartic Proteinases (Cyprosins) from Flowers of Cynara cardunculus SUBSP. flavescens CV. Cardoon
10. Structural and Functional Aspects of Cardosins
11. Thermodynamics and Proton Uptake for Pepstatin Binding to Retroviral and Eukaryotic Aspartic Proteases
12. Acid Proteinase From Nepenthes distillatoria (Badura)
13. Substrate Specificity of Non-Pepsin-Type Acid Proteinase, Aspergillus niger Proteinase A
14. An Aspartic Proteinase from Flowers of Centaurea calcitrapa : Purification, Characterization, Molecular Cloning, and Modelling of Its Three-Dimensional Structure
15. A Comparative Study on the Aspartic Proteinases from Different Species of Cynara
16. Crystallisation, Structure Solution, and Initial Refinement of Plant Cardosin-A
17. Molecular Cloning of Aspartic Proteinases from Flowers of Cynara cardunculus SUBSP. flavescens CV. Cardoon and Centaurea calcitrapa
18. Plasmepsins I and II from the Malarial Parasite Plasmodium falciparum
19. Aspartic Proteinases and Inhibitors in Plant Pathogenesis
20. Primary Substrate Specificities of Secreted Aspartic Proteases of Candida albicans
21. Studies on Plasmepsins I and II from the Malarial Parasite Plasmodium falciparum and their Exploitation as Drug Targets
22. Structural Analysis of Plasmepsin II : A Comparison with Human Aspartic Proteases
23. Screening Aspartyl Proteases with Combinatorial Libraries
24. Pepstatin-Insensitive Carboxyl Proteinases from Prokaryotes : Catalytic Residues and Substrate Specificities
25. Functional Aspects of Secreted Candida Proteinases
26. Bacterial Aspartic Proteinases as Novel Antibiotic Targets
27. Development and Testing of Inhibitors of Candida Aspartic Proteinases
28. Structural Thermodynamic Study of the Binding of Renin Inhibitors to Endothiapepsin
29. Structure of Secreted Aspartic Proteinases from Candida : Implications for the Design of Antifungal Agents
30. Yapsin1 : Structure, Biosynthesis, and Specificity
31. Proteolytic and Non-Proteolytic Activation of Prorenin
32. Rhizomucor miehei Aspartic Proteinases Having Improved Properties
33. Aspergillus niger Acid Proteinase A : Structure and Function
34. Crystal Structure of The Rhizomucor miehei Aspartic Proteinase
35. Activation Mechanism of Pepsinogen as Compared to the Processing of HIV Protease gag-pol Precursor Protein
36. Cardosinogen A : The Precursor Form of the Major Aspartic Proteinase from Cardoon
37. The Roles of the Basic Residues in the Prosegment of Aspergillopepsinogen I
38. Detailed Analysis of Human Cathepsin E Prime Region Specificity
39. Skin Surface Proteolytic Activity : Partial Characterization and Identification
40. Epitope Mapping of Recombinant Human Procathepsin D
41. Cathepsin E in the Central Nervous System
42. Construction of Chimeric Enzymes to Probe Subsite Contributions to Catalytic Specificity
43. Expression of Chimeric Human Aspartic Proteinases
44. Expression of Multiple Genes for Pregnancy-Associated Glycoproteins in the Sheep Placenta
45. Cathepsin E : The Best Laid Plans of Mice and Men
46. Mass Spectrometry as a Tool for Studying the Action of Human Aspartic Proteases on Peptides and Proteins
47. Biosynthesis and Intracellular Targeting of the Lysosomal Aspartic Proteinase Cathepsin D
48. Post X-Ray Crystallographic Studies of Chymosin Specificity : The Role of Histidine-Proline Cluster of κ-Casein in Catalytic Reactions
49. An Aspartic Proteinase Expressed in the Equine Placenta
50. Protein Engineering Aspartic Proteinases : Site-Directed Mutagenesis, Biochemical Characterisation, and X-Ray Analysis of Chymosins with Substituted Single Amino Acid Substitutions and Loop Replacements
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