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This book focuses on natural products, in particular medicinal plants and their derived products, as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics, including wide availability, diverse pharmacological actions, and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying the efficacy and safety of medicinal plants and phytochemicals in treating human diseases. A plethora of basic studies has also unraveled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products, and drug interactions remain to be systematically documented. Bioprospecting of Tropical Medicinal Plants represents a comprehensive analysis of natural products, mainly medicinal plants and phytochemicals. It includes detailed medicinal properties and pharmacological action from in vitro models to clinical trials. The goal is to present the readers a carefully curated collection of plant-derived natural products and their underlying molecular mechanisms.

Developments in Geotechnical Engineering, Vol. 14B: Rockslides and Avalanches, 2: Engineering Sites focuses on initiatives to offer a foundation for studies of mass movement phenomena in the Western Hemisphere. The selection first takes a look at the contributions of Josef Stini to engineering, geology, and slope movement investigations, the concept of Karl Terzhagi on rockslides, and the contributions of Laurits Bjerrum to the mechanics of rockslides. Concerns cover stability of hard rock slopes, influence of geological details, relation between slide process and remedial treatment, water pressure in pores and fractures, slope creep, rockslides, and avalanches, and early warning of an impending slide. The publication then examines rock slope movements with hydroelectric power projects in Mexico, Bighorn Reservoir slides in Montana, U.S.A., rock avalanche and wave at Chungar, Peru, and wedge rockslides in Libby Dam and Lake Koocanusa in Montana. The text examines Hogarth Pit slope failure in Ontario, Canada, pit slope performance in shale in Wyoming U.S.A., Twin Buttes pit slope failure in Arizona, U.S.A., and the Prime Mine slope failure in Arizona, U.S.A. Discussions focus on stability analyses, description of slope failures, cause of failure, remedial actions, geotechnical properties of tertiary shales, and subsequent slope performance. The selection is a valuable source of data for researchers interested in rockslides and avalanches.