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Immunology has emerged as a key component of the curricula of graduate and postgraduate courses in biotechnology, microbiology, biochemistry, bioinformatics, and other interdisciplinary fields of biology, including zoology, veterinary science, and medicine. As a basic introductory textbook on one of the fastest-moving and most challenging areas of immunological science, this book contains the most recent information about immunologic mechanisms and their importance, along with various molecular techniques employed in immunology. The short and concise text helps make the structures, processes, and interactions of the immune system easily comprehensible. The book includes chapters on immunoinformatics as well as the immune system of the brain, rarely found in any of the immunology books published so far. Many diverse and interesting aspects of the advances in immunology have also been covered, including tumor immunology and immunodeficiency disorders. The easy-to-understand concepts presented in the textbook make it an ideal companion for learners preparing for competitive and other examinations. Undergraduate, postgraduate, and PhD students, people from the industry and academia, and research scholars will immensely benefit from it.

This textbook is based on the curriculum for US, UK, Canadian and Australasian Orthopedic trainees. It offers an in-depth summary of the knowledge needed to pass the boards and FRCS examination in Trauma and Orthopedic surgery. The focus is on basic information on every orthopedic subspecialty, including: surgical anatomy, basic sciences, adult reconstruction, pediatric orthopedics, foot and ankle surgery, orthopedic pathology, the spine, sports surgery, upper limb, wrist and hand surgery, and orthopedic traumas. All sections are written by experts in the respective field and utilize a consistent bullet-point format, chosen to facilitate the learning experience and help readers memorize and organize knowledge. A clear and concise “take-home message” section precedes each topic, and key references are highlighted at the end of each chapter.

This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of antisense molecules to hinder abnormal gene expression. Clinical studies detail several different strategies for the treatment of cancer and cardiovascular diseases, using genetic material as therapeutic agents. The regulatory issues governing the use of gene therapy in Europe and the United States are also presented. This book highlights the range of applications and demonstrates the rapid progress being made in the field of gene therapy.

It is like a fairy story! Or at least a beautiful epic, a truly significant page in the history of medicine, a staggering scene in which several actors come into play, both fundamentalists and clinical practitioners, eager to place all these new developments at the disposal of those suffering from ill health. Everyone is passionate about their work, be it providing new knowledge or perfecting new therapeutic methods. Man has always been fascinated by the possibility of replacing a damaged organ with a healthy one. Several attempts have been made over the centuries, and some miracles have been reported, such as those of Saint Damien and Saint Come as illustrated by Fra Angelico. The modern saga, however, started more modestly on the mouse. It is on the mouse that the first tissue group was discovered; yet the study of human tissue groups could only be carried out on a human. One human must be subjected to the thousands of tests that have enabled us to unravel the extraordinary complexity of the HLA system.

The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce, Kidney and Pancreas Transplantation: A Practical Guide. This volume is devoted to kidney and pancreas transplantation and is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation. Kidney and Pancreas Transplantation: A Practical Guide will be of great value to transplant physicians as well as medical and surgical fellows who intend to pursue an interest in transplantation.

Joined by an international team of leading experts, noted pain authority Dr. Steven Waldman presents comprehensive, one-of-a-kind coverage examining pain syndromes from a multidisciplinary perspective. A user-friendly, how-to-do-it format enables you to access specific guidance quickly...and apply the information easily...to bring faster pain relief to your patients.Presents the practice-proven experience of Steven D. Waldman, MD - author of numerous groundbreaking pain management references - along with world leading experts.Uses a templated, color-coded format to facilitate fast and easy reference.Offers state-of-the-art techniques for the diagnosis and treatment of pain syndromes.

A representation of the skills and expertise of leading surgeons in the field, this reference serves as a step-by-step instructional resource on arthroscopic and minimally invasive surgery of the shoulder and elbow. With full-color illustrations throughout, each chapter focuses on specific techniques and will contain strategies to enhance recovery,

Title from ebook title screen (viewed on Feb. 19, 2004).

Recent advances in immunology and molecular biology have resulted in new therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation, and interplay of cells involved in anti-tumor immunity have made the clinical control of some cancers more plausible than previously tho