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The Anterior Cruciate Ligament: Reconstruction and Basic Science, 2nd Edition, by Dr. Chadwick Prodromos, provides the expert guidance you need to effectively select the right procedure and equipment, prevent complications, and improve outcomes for every patient. Written and edited by world leaders in hamstring, allograft, and bone-patellar tendon-bone (BTB) ACL reconstruction, this revised reference is a must-have resource for the full range of anterior cruciate ligament reconstruction techniques, plus fixation devices, rehabilitation, revision ACLR surgery, and much more! - Covers the latest clinical and technical information on pain control, genetics and biologics, the use of ultrasound, and much more. - EBook access features an exhaustive ACL bibliography database more than 5000 available articles. - Features dozens of new chapters that offer up-to-date information on pain control after ACLR, single vs. double bundle repairs, genetics and collagen type, all-inside techniques, biologics, pediatrics, ACL ganglion cysts, prognosis for ACLR success, allografts vs. autografts, and more. - Provides the experience and insight of a'dream team'of ACL experts, including James Andrews on sports medicine, Frank Noyes on HTO and ACLR, and Andrew Amis on the benefits of the older femoral tunnel placement technique. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Following in the tradition of the previous editions, this book offers the latest research and most up-to-date information on orofacial pain, including a concise overview of each condition as well as its symptoms, comorbidities, differential diagnosis, and treatment options. Every chapter has undergone critical updates to reflect the developments in the expanding field of orofacial pain. These updates include the addition of new diseases such as first-bite syndrome, revised information on genetic factors to reflect new insights gleaned from the OPPERA studies, expanded information on management strategies for certain conditions, and revisions to screening tools for biobehavioral factors. In addition, the classification system used in the fifth edition has been replaced and extended to include DSM-5 codes where applicable. This book remains an essential tool for any health care provider who treats patients with orofacial pain. Contents Patient Assessment • Diagnostic Classification • Intracranial Causes • Primary Headache Disorders • Neuropathic Pain • Intraoral Pain Disorders • TMDs • Cervical Spinal Disorders and Headaches • Causes of Head and Facial Pain • Sleep • Biobehavioral Considerations

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.The chapter'Open-Label Single-Sequence Crossover Study Evaluating Pharmacokinetics, Efficacy, and Safety of Once-Daily Dosing of Nitisinone in Patients with Hereditary Tyrosinemia Type 1 (HT-1)'is open access under a CC BY 4.0 license via link.springer.com.

In this book, leading experts employ an evidence-based approach to provide clear practical guidance on the important question of when and how to facilitate return to play after some of the most common injuries encountered in football. Detailed attention is paid to biomechanics, the female athlete, risk factors, injury prevention, current strategies and criteria for safe return to play, and future developments. Specific topics discussed in depth include concussion, anterior cruciate ligament and other knee injuries, back pathology, rotator cuff tears, shoulder instability, hip arthroscopy, and foot and ankle injuries. The chapter authors include renowned clinicians and scientists from across the world who work in the field of orthopaedics and sports medicine. Furthermore, experiences from team physicians involved in the Olympics, National Football League (NFL), Union of European Football Associations (UEFA), and Fédération Internationale de Football Association (FIFA) are shared with the reader. All who are involved in the care of injured footballers will find this book, published in cooperation with ESSKA, to be an invaluable, comprehensive, and up-to-date reference that casts light on a range of controversial issues.

The Cerebellum: From Embryology to Diagnostic Investigations, Volume 154 is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: Neuroimaging, and includes content on conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders). - Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases - Explores the long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseases - Features chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases

This book addresses relevant issues to enhance pain management nurses need to advocate for effective pain treatment in the elderly. Significant changes in the evolving nursing and healthcare environment require adequate information on this topic, as pain is a very challenging area. As other care professionals, nurses are daily confronted with issues on pain assessment and management. This volume offers an overview within an evolving health environment, in which nurses dealing with pain play a growing role. It showcases best practices in pain assessment and management, details non pharmacological and pharmacological treatments. It also addresses core issues defined by the International Association for the Study of Pain (IASP), such as knowledge translation, that are most relevant for clinical nurses, student nurses, nurse researchers as well as other care professionals.

Neurological diseases such as cerebral stroke, dementia, and Parkinson=s disease are the most frequent causes of swallowing disturbances. Neurogenic dysphagias are playing an increasingly important role in outpatient and in-patient care due to their often severe health sequelae and the increasing ageing of the population. In a practically oriented way, this established reference work discusses the neurophysiological basis, as well as the diagnosis and treatment of neurogenic dysphagias, reflecting the rapid developments in this field during the last 15 years. A special focus in the book is carrying out and reporting on the endoscopic evaluation of neurogenic dysphagias. Since 2015, the German Association for Neurology and the German Stroke Association have been offering a Flexible Endoscopic Examination of Swallowing (FEES) training curriculum for neurogenic dysphagias, and the German Association for Geriatric Medicine has also joined with the project. All of the content requirements for the FEES training curriculum are covered in this expanded and revised second edition of the book. Example FEES videos for various patterns of disturbance can be downloaded as additional materials.

This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high-quality illustrations, line drawings, and radiographs that provide a step-by-step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations. Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non-surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors. The most encyclopedic book on the pancreas—providing outstanding and clear guidance for the practicing clinician Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management Completely updated with brand new chapters Over 500 downloadable illustrations An editor and author team of high international repute who present global best-practice The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.

This book provides up-to-date information on all aspects of orofacial pain biomarkers. It opens by presenting background information on clinical phenotypes and the neurobiological substrates underlying chronic orofacial pain and by explaining the potential role of biomarkers in the diagnosis, prognostic evaluation, and treatment of orofacial pain. The main section of the book examines the contribution of human and animal studies to the field of biomarkers for orofacial pain and discusses biomarkers for masticatory muscle pain, temporomandibular joint pain, neuropathic face pain, and autonomic nervous system involvement in trigeminal facial pain. The potential impacts of the immune system on orofacial pain biomarkers and candidate gene phenotypes with possible links to chronic orofacial pain conditions are also addressed, and differences and similarities between saliva and serum biomarkers for pain are explained as well. The final section covers research-related issues in assessment methods and statistical analyses used in evaluating biomarkers, identifies future challenges and suggests new directions in the field.

Pain Medicine Board Review is a comprehensive guide for preparing for the American Board of Medical Specialties (ABMS) certification or recertification in Pain Medicine, and for residents preparing for in-training examinations in Pain Medicine. The text is organized into 28 chapters covering topics such as Anatomy, Physiology of Pain, Pharmacology, Diagnosis of Pain, and various pain syndromes. Each section includes questions, answers, and detailed explanations with highlighted key points, and concise further reading lists. Questions follow the ABMS style, and the explications of answers carefully address all points in the ABMS content outline for Pain Medicine. A section on imaging includes high quality magnetic resonance images, ultrasound images, fluoroscopic images and other images that will enable the examination candidate to answer questions that determine knowledge of pathological states as compared to normal and complications of treatments.

This updated and expanded new edition of a successful book describes genetic diagnostic entities of neuromuscular disorders. Neuromuscular syndromes are presented clinically either as a case study or as an overview from the literature, accompanied by text presenting molecular defects, and differential diagnosis.This collection of neuromuscular disorders features the differential clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diagnosis. Key points for each genetic disease are identified to suggest treatment, when available, or the main clinical exams useful in follow-up of patients. Genetic Neuromuscular Disorders: A Case-Based Approach is aimed at neuromuscular physicians and neurology residents.

This book is a concise guide to the clinical diagnosis and management of chronic pancreatitis, presenting the latest research into the disease. It focuses on pathogenesis, epidemiology, genetics, diagnosis, endoscopic and surgical treatment, and prognosis. It also offers comprehensive descriptions of 4 diagnostic methods and discusses the contemporary management of chronic pancreatitis, including conservative, ESWL, interventional and surgical treatments. The final chapter includes 6 typical case presentations, which taken together provide a standard description of this condition.

This new book discusses advances in research on evoked potentials and electrical stimulation. Chapters One describes the neurophysiological immediate and short-term changes that occur in the nervous system structures of patients assessed in three different contexts of work: Intraoperative Neurophysiologic Monitoring (IONM), ICU, and in the Clinical Neurophysiological Laboratory. Chapter Two focuses on the importance of cortical evoked potentials to analyze the neurophysiological correlates of migraines, strokes and related psychiatric complications, paying particular attention to the possible implications in terms of clinical applications and future research. Chapter Three analyzes electric stimulation in stroke patients. Chapter Four explores the effects of oxidative stress on brain electrical activity and its repercussions on sensory organization in geriatric rhesus monkeys in captivity. The final chapter provides a short communication on visually evoked potentials in rhesus monkeys.

In recent years, empathy has received considerable research attention as a means of understanding a range of psychological phenomena, and it is fast drawing attention within the fields of music psychology and music education. This volume seeks to promote and stimulate further research in music and empathy, with contributions from many of the leading scholars in the fields of music psychology, neuroscience, music philosophy and education. It exposes current developmental, cognitive, social and philosophical perspectives on research in music and empathy, and considers the notion in relation to our engagement with different types of music and media. Following a Prologue, the volume presents twelve chapters organised into two main areas of enquiry. The first section, entitled'Empathy and Musical Engagement', explores empathy in music education and therapy settings, and provides social, cognitive and philosophical perspectives about empathy in relation to our interaction with music. The second section, entitled'Empathy in Performing Together', provides insights into the role of empathy across non-Western, classical, jazz and popular performance domains. This book will be of interest to music educators, musicologists, performers and practitioners, as well as scholars from other disciplines with an interest in empathy research.Chapter 5 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

This book provides readers with the latest developments in neurosciences research. Chapter One reviews the changes that occur in the muscle and neuromuscular junctions following nerve injury and discusses possible strategies to prevent muscle atrophy. Chapter Two focuses on the contribution of the anterior cingulate cortex in pain processing. Chapter Three discusses the role of the anterior cingulate cortex in the arising of awareness deficits in neurocognitive disorder, acquired brain injuries, mood disorders and psychosis. Chapter Four discusses the relationship between neuroplasticity and cognitive empowerment. Chapter Five investigates if cognitive empowerment through Eye Tracker technologies increases both neuropsychological and neurophysiological measures in patients with Rett Syndrome (RS).

This book collects contributions to the XXIII international conference “Nonlinear dynamics of electronic systems”. Topics range from non-linearity in electronic circuits to synchronisation effects in complex networks to biological systems, neural dynamics and the complex organisation of the brain. Resting on a solid mathematical basis, these investigations address highly interdisciplinary problems in physics, engineering, biology and biochemistry.

Developmental Disorders of the Brain: Brain and Behaviour addresses disabilities that occur or have their roots in the early, developmental phase of life which are of utmost concern to parents, siblings, carers and teachers.This text describes the latest clinical and behavioral findings of disorders which largely or entirely involve the frontostriatal (basal ganglia) system including Tourette's, Obsessive-Compulsive and Attention-Deficit-Hyperactivity disorders, Schizophrenia, Autism, gambling and addiction, depression, and Conduct, Developmental Motor Co-ordination, and language disorders. Examples of disorders involving the frontocerebellar are also described such as Asperger's disorder, Williams, Fragile X, and Cerebellar Cognitive Affective syndromes, and Friedreich Ataxia. This book also discusses the relevant anatomy, physiology and pathology, and some of the major functions mediated by affected or relevant structures, together with accounts of the latest recording, brain imaging and stimulating techniques related to these kinds of disorders.Covering both frontostriatal and frontocerebellar, systems which control and direct normal behavior, and which can fail with often distressing consequences during development, as well as addressing behavioural, clinical, pathophysiological and technical aspects, this text is vital to understanding, diagnosis and management of developmental disorders of the brain. This text will be of great interest to clinicians, researchers, teachers and parents.

The European Pain Federation EFIC is made up of Chapters of the International Association for the Study of Pain (IASP). Its Health Care Professionals look after a population of over 740 million people in its 37 member countries. European Pain Management provides a review of the organization and delivery of pain care in the 37 European countries. Leaders in the field of pain management from each country offer a chapter on how their health and pain care services are organized, the demands of their specific populations, the specific national challenges they face, and examples of innovations and advances. After this comprehensive summary, key experts in the field discuss issues that are pertinent to all the European nations; ranging from working with young people to managing opioids, and the rise of pain as a specialism. The final chapter pulls together themes from across the entire book, making a call to envision a new form of pain management for a new Europe. European Pain Management provides an authoritative summary, description, and discussion of the challenges and opportunities for improving the care of people living in pain.

This book covers recent advances in the understanding of brain structure, function and disorders based on the fundamental principles of physics. It covers a broad range of physical phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the mind. It provides novel insights into the devastating brain disorders of the mind such as schizophrenia, dementia, autism, aging or addictions, as well as into the new devices for brain repair. The book is aimed at basic researchers in the fields of neuroscience, physics, biophysics and clinicians in the fields of neurology, neurosurgery, psychology, psychiatry.

The phenomenon of pain presents problems and puzzles for philosophers who want to understand its nature. Though pain might seem simple, there has been disagreement since Aristotle about whether pain is an emotion, sensation, perception, or disturbed state of the body. Despite advances in psychology, neuroscience, and medicine, pain is still poorly understood and multiple theories of pain abound.The Routledge Handbook of Philosophy of Pain is an outstanding reference source to the key topics, problems, and debates in this exciting and interdisciplinary subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors the Handbook is divided into nine clear parts: Modeling pain in philosophy Modeling pain in neuroscience Modeling pain in psychology Pain in philosophy of mind Pain in epistemology Pain in philosophy of religion Pain in ethics Pain in medicine Pain in law As well as fundamental topics in the philosophy of pain such as the nature, role, and value of pain, many other important topics are covered including the neurological pathways involved in pain processing; biopsychosocial and cognitive-behavioural models of pain; chronic pain; pain and non-human animals; pain and knowledge; controlled substances for pain; pain and placebo effects; and pain and physician-assisted suicide.The Routledge Handbook of Philosophy of Pain is essential reading for students and researchers in philosophy of mind, philosophy of psychology and ethics. It will also be very useful to researchers of pain from any field, especially those in psychology, medicine, and health studies.

Authored by world renowned scientists, this book expertly reviews all the imaging techniques and exciting new methods for the analysis of the pain, including novel tracers, biomarker, metabolomic and gene-array profiling, together with cellular, genetic, and molecular approaches. Recent advances in human brain imaging techniques have allowed a better understand of the functional connectivity in pain pathways, as well as the functional and anatomical alterations that occur in chronic pain patients. Modern imaging techniques have permitted rapid progress in the understanding of networks in the brain related to pain processing and those related to different types of pain modulation. Neuroimaging of Pain is designed to be a valuable resource for radiologists, neuroradiologists, neurologists and neuroscientists, working in hospitals and universities from junior trainees to consultants.

En este Volumen II se facilita certeramente la comprensión fisiopatológica delas herramientas diagnósticas y terapéuticas que requiere la estratificación del riesgo cardiovascular, el diagnóstico de este grupo de patologías y el amplio espectro de su manejo.Es llamativamente ameno y de fácil manejo para su enorme extensión, enseñará atodo profesional interesado, los secretos de un apropiado tratamiento y prevención en este campo. Junto al Volumen I compone una obra más que única, imprescindible.Los Volúmenes I y II de Control Global del Riesgo Cardiometabólico conforman el primer tratado en castellano de la llamada Medicina Cardiometabólica (MCM),también conocida como'Salud Cardiometabólica', nacida en Boston en 2006. Estanueva medicina multidisciplinar es más predictiva, preventiva, anticipativa ypersonalizada que la medicina cardiovascular clásica. Además, hay una interconexión entre la MCM y la Medicina Antiaging que la medicina cardiovascular clásica no tiene. Una relación que tiene como base fisiopatológica la llamada teoría vascular del envejecimiento humano. Por último, la MCM es mucho más que lasuma de cardiovascular y metabolismo, implica notables mejoras en objetividad, precisión y seguridad.

This unique and richly illustrated volume presents the state of the art in the comprehensive management of major neurosurgical diseases in the elderly (aged 65 and over). It explores all of the common neurosurgical pathologies affecting elderly patients, and emphasizes the paramount importance of tailored management strategies for quality of life. It highlights updated techniques for anaesthesia and critical care, as well as minimally invasive neurosurgical methods intended for this specific group of patients. Radiosurgery treatment is also discussed, in particular for brain tumours.In western societies, the proportion of elderly citizens has nearly reached 20%, and shows no signs of slowing down. The management of neurosurgical conditions in this particular population requires specific multidisciplinary strategies. To address this situation, a team of internationally respected contributors accurately describe degenerative and traumatic spinal diseases, which account for the majority of admissions among the elderly, as well as brain tumours and intracranial haemorrhages, aspects that are raising new ethical issues. The book mainly addresses the needs of neurosurgeons and geriatric neurologists, but also neuro-oncologists and neuro-anaesthesists working with elderly patients, as well as students in these disciplines.

A resource that combines oncologic principles with treatment plans for the surgical management of neoplasms Textbook of General Surgical Oncology is a practical and comprehensive reference that offers authoritative coverage of a wide variety of oncologic concepts and disorders. The book opens with detailed discussion of the general principles of molecular biology, cancer epidemiology, surgical oncology, radiation oncology, medical oncology, immunotherapy, nuclear imaging, and molecular diagnostics. The text then focuses on site-specific neoplasms, such as those of the skin, soft tissue, bone, head/neck, brain, lung, mediastinum, breast, pleura, peritoneum, as well as tumors that affect various systems, including the endocrine, gastrointestinal, hepatobiliary, genitourinary, gynecologic, and hematopoietic. · Each chapters is written by an internationally recognized expert on the topic · Learning aids include chapter-ending Q&A and Practical Pearls · Outstanding review for the new General Surgical Oncology certification examination

This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

This is the second of four volumes that together offer an authoritative, in-depth reference guide covering all aspects of the management of oral cancer from a multidisciplinary perspective and on the basis of a strong scientific foundation. This volume addresses a range of management issues in oral cancer, from imaging and staging through to the roles of radiation therapy and chemotherapy. Principles of ablative surgery are explained, and neck dissection and sentinel lymph node biopsy techniques, described. Detailed consideration is also given to the management of complications, salvage surgery and re-radiation, the biologic basis of treatment failure, and emerging approaches to overcome treatment resistance. The inclusion of resource-stratified guidelines will meet the needs of practitioners in different geographic regions with varying resources.Overview on all volumes:Volume 1: Biology, Epidemiology, Etiology, and PreventionVolume 2: Diagnosis and ManagementVolume 3: Oral and Maxillofacial Reconstructive Surgery Volume 4: Rehabilitation and Supportive Care

This book aims to provide clinicians and other practitioners and professionals with up-to-date information on how to evaluate and manage headaches in children and adolescents, highlighting the most recent recommendations. Unlike in other books on the subject, detailed attention is devoted to the various comorbidities commonly associated with headache, including psychiatric comorbidities such as depression, anxiety, attention deficit hyperactivity disorder, and learning disabilities and medical conditions such as epilepsy, vascular disorders, brain tumors, atopic disease, and obesity. The intimate link between these conditions and headache is explained with a view to enabling the reader to recognize their presence and, on that basis, to institute the most effective pharmacological or non-pharmacological treatment strategy. Moreover, knowledge of the comorbidities associated with headache will help readers to understand more fully the causes of this serious disorder and also its consequences, e.g., for school performance, relationships, and daily activities. The authors are all international experts who care for children with headache or the other described disorders.

This volume presents a summary of recent research and debates on old and new aspects in stroke medicine. The volume covers topics such as causative factors of stroke such as hypertension, the immune system, genetic factors and the neurovegetative system, to the role of new imaging techniques in improving diagnosis and treatment, from preventive therapy and recanalization to the important and intriguing effects of neuroprotection, neuroregeneration and post stroke rehabilitation. Readers will be able to understand perspectives from stroke medicine researchers about the relationship between the nervous system and other physiological systems in the body and their role in the onset and treatment of stroke. The volume is intended as a resource for neurologists and medical professionals involved in other specialties such as cardiology, internal medicine, rehabilitation and physiology.

Non-motor Parkinson's: The Hidden Face-Management and the Hidden Face of Related Disorders, Volume 134, the latest release in the International Review of Neurobiology series, is an up-to-date and comprehensive textbook addressing non-motor aspects of Parkinson's disease, a key unmet need. Specific chapters in this updated release include Therapeutics and NMS in PD, Non-motor effects of conventional and transdermal therapies in PD, Infusion therapy, CDD and NMS in PD, DBS and NMS in PD, TMS and implications for NMS in PD, Botulinum toxin therapy and NMS in PD, and Nutrition and NMS in PD, amongst others. Including practical tips for non-specialists and clinical algorithms, the book contains contributions from over 40 opinion leaders in the field of movement disorders. It provides practitioners and researchers with a laboratory, to bedside, to caregiver perspective. - Presents a comprehensive textbook on the non motor aspects of Parkinson's disease - Includes practical tips and clinical algorithms, and is the only textbook to bring a holistic approach - Contains contributions from over 40 global opinion leaders in the field of movement disorders - Provides special chapters on exercise, personalized medicine, osteoporosis, genetics, treatment aspects and nutrition

This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors

This book will serve as the preeminent text book on the topic of'base excision repair', a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of'base excision repair'. It includes chapters by many of the most established investigators in the field, from all over the world.

Following in the steps of the bestselling Sleep Medicine Pearls, this practical resource provides authoritative guidance on the evaluation and management of common pediatric sleep medicine problems using concise clinical vignettes. Experts in this rapidly growing field, led by Drs. Lourdes M. Del Rosso, Richard B. Berry, Suzanne E. Beck, Mary H. Wagner, and Carole L. Marcus, provide a hands-on, case-based approach, perfect for physicians studying for the sleep boards, fellows learning sleep medicine, and physicians who see children in their practice. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Over 95 cases review key elements in the evaluation and management of a wide variety of pediatric sleep disorders. - An easy-to-read'pearls'format summarizes 2 to 5 major teaching points for maximum retention. Short, templated chapters are ideal for use by busy physicians. - Current scoring criteria from the American Academy of Sleep Medicine manual for sleep and associated events version 2.2, as well as the current International Classification of Sleep Disorders, 3rd Edition (ICSD-3). - Expert coverage of normal sleep in children, as well as sleep disorders associated with common medical, neurologic, psychiatric, neurodevelopmental, and genetic conditions. - Up-to-date information on pediatric obstructive sleep apnea syndrome diagnosis and management. - Numerous illustrations of polysomnographic fragments and pictures of clinical findings help you quickly recognize key pediatric sleep patterns that lead to an accurate diagnosis. All illustrations online are in full color. - An ideal resource for pediatric sleep medicine specialists, adult sleep medicine specialists, pediatric pulmonologists, pediatric neurologists, pediatric otolaryngologists, general pediatricians, and pediatric psychologists.

In dem etablierten Standardwerk zur Schmerzpsychologie und –psychotherapie geben die renommierten Herausgeber und Autoren sowohl eine Einführung in die wissenschaftlichen Grundlagen und Konzepte als auch einen Überblick über bereits etablierte und in der Entwicklung befindlichen Behandlungskonzepte. Damit fördert das Werk das Verständnis für die schmerztherapeutische Praxis und ist hervorragend geeignet für die schmerzpsychotherapeutische Fort- und Weiterbildung.Die 8. Auflage wurde grundlegend überarbeitet und wird von den Ausbildungskommissionen der Deutschen Gesellschaft für Schmerztherapie e.V. und der Deutschen Gesellschaft für psychologische Schmerztherapie und -forschung empfohlen.

Der Anblick von Personifikationen im Palazzo dei Conservatori in Rom oder im westanatolischen Aphrodisias wirft viele Fragen hinsichtlich der Visualisierung und medialen Vermittlung imperialer Herrschaft auf: In welchen bildlichen und textlichen Formen stellten die Römer die Ausdehnung ihrer Machtsphäre dar? Was zählten sie überhaupt dazu? Zugleich fragt Marco Vitale in dieser Studie nach der Perspektive der Beherrschten bzw. ihren Selbstdarstellungen. Ziel ist es, die ethnographischen, geographischen und juristisch-administrativen Auswahl- und Anordnungsprinzipien zu erkennen, nach denen Herrschaftsgebiete vorzugsweise und kohärent dargestellt wurden. Das Quellenmaterial setzt sich auf der Ebene der Bildersprache aus Monumenten, Steinreliefs, Münzabbildungen sowie Gegenständen der Kleinkunst zusammen. Auf der sprachlichen Ebene geben Münzlegenden und amtliche Dokumente in Steininschriften sowie Zeugnisse literarischer Kunst- oder juristischer Fachsprache Aufschluss. Die Quellenanalyse zeigt, wie wenig statisch und mit modernen Konzepten nur teilweise fassbar der Begriff des'Reiches'ist, wenn man ihn in den von Herrschern und Beherrschten versinnbildlichten Formen betrachtet.

Migraine is a complex neurological disorder that is characterized by a complex neurobiology, clinical features that may overlap with over 300 causes of headache, and an association with major medical illnesses and comorbid diseases. This books draws upon the authors'vast clinical experience and exhaustive knowledge of the science of migraine and the practice of headache medicine and provides this knowledge in a comprehensive yet digestible format. While migraine is often a subject in other textbooks on headache, it is the sole focus of this volume. The authors provide an up-to-date overview of the evidence base and combine this with their experience and expertise to help practitioners make informed treatment decisions. This book also provides a glimpse into the future describing new treatment modalities, including neurostimulation technologies and biologics that are emerging as potentially valuable treatment options. The authors also deal extensively with the unique and complex management of migraine in women throughout the reproductive life cycle. For those looking for a practical, insightful, and in-depth review on the subject of migraine, there is no other option.

Essentials of the Cerebellum and Cerebellar Disorders is the first book of its kind written specifically for graduate students and clinicians. It is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. This monograph makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from ataxia clinics and cerebellar laboratories throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.

Systems-level neuronal mechanisms that coordinate the temporally, anatomically, and functionally distributed neuronal activity into coherent cognitive operations in the human brain have remained poorly understood. In humans, neuronal oscillations and synchronization can be recorded non-invasively with electro- and magnetoencephalography (EEG and MEG) that have excellent temporal resolution and an adequate spatial resolution when combined with source-reconstruction methods. In this book, leading authors in the field describe how recent methodological advances have paved the way to several major breakthroughs in the observations of large-scale synchrony from human non-invasive MEG data. This volume also presents the caveats influencing analyses of synchronization. These include the non-homogeneous sensitivity of MEG to superficial cortical sources, and, most importantly, the multitude of consequences of linear mixing. Linear mixing is an immense confounder in the sensor-level analyses of synchronization, but is also present at the source level. Approaches that can be used to avoid or compensate for these issues are then discussed. Thereafter, several authors take up a number of the functional roles that large-scale synchronization has in cognition. The authors assess how the spatio–temporal and –spectral organization and strength of both local and large-scale synchronized networks are associated with conscious sensory perception, visual working memory functions, and attention. These chapters summarize several lines of research showing how the strength of local and inter-areal oscillations in both cortical and subcortical brain structures is correlated with cognitive functions. Together these data suggest that synchronized neuronal oscillations may be a systems-level neuronal mechanism underlying the coordination of distributed processing in human cognition. In line with this argument, other authors go on to describe how oscillations and synchronization are altered in clinical populations, complementing the data presented on healthy subjects. Importantly, this book includes chapters from authors using many different approaches to the analyses of neuronal oscillations, ranging from local oscillatory activities to the usage of graph theoretical tools in the analyses of synchronization. In this way the present volume provides a comprehensive view on the analyses and functional significance of neuronal oscillations in humans. This book is aimed at doctoral and post-doctoral students as well as research scientists in the fields of cognitive neuroscience, psychology, medicine, and neurosciences.

In this thorough revision, updating, and expansion of his great 2007 book, Empathy in Patient Care, Professor Hojat offers all of us in healthcare education an uplifting magnum opus that is sure to greatly enhance how we conceptualize, measure, and teach the central professional virtue of empathy. Hojat's new Empathy in Health Professions Education and Patient Care provides students and professionals across healthcare with the most scientifically rigorous, conceptually vivid, and comprehensive statement ever produced proving once and for all what we all know intuitively – empathy is healing both for those who receive it and for those who give it. This book is filled with great science, great philosophizing, and great ‘how to'approaches to education. Every student and practitioner in healthcare today should read this and keep it by the bedside in a permanent place of honor.Stephen G Post, Ph.D., Professor of Preventive Medicine, and Founding Director of the Center for Medical Humanities, Compassionate Care, and Bioethics, School of Medicine, Stony Brook University Dr. Hojat has provided, in this new edition, a definitive resource for the evolving area of empathy research and education. For those engaged in medical student or resident education and especially for those dedicated to efforts to improve the patient experience, this book is a treasure trove of primary work in the field of empathy.Leonard H. Calabrese, D.O., Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityThe latest edition of Empathy in Health Professions Education and Patient Care grounds the clinical art of empathic caring in the newly recognized contributions of brain imagery and social cognitive neuroscience. Furthermore, it updates the accumulating empirical evidence for the clinical effects of empathy that has been facilitated by the widespread use of the Jefferson Scale of Empathy, a generative contribution to clinical research by this book's author. In addition, the book is so coherently structured that each chapter contributes to an overall understanding of empathy, while also covering its subject so well that it could stand alone. This makes Empathy in Health Professions Education and Patient Care an excellent choice for clinicians, students, educators and researchers.Herbert Adler, M.D., Ph.D. Clinical Professor of Psychiatry and Human Behavior,Sidney Kimmel Medical College at Thomas Jefferson UniversityIt is my firm belief that empathy as defined and assessed by Dr. Hojat in his seminal book has far reaching implications for other areas of human interaction including business, management, government, economics, and international relations.Amir H. Mehryar, Ph.D., Emeritus Professor ofBehavioral Sciences and Population Studies, Institute for Research and Training in Management and Planning, Tehran, Iran

Pediatric Neuro-Ophthalmology, 3rd edition provides the single authoritative resource on the pathophysiology, diagnostic evaluation, and treatment of neuro-ophthalmologic disorders in children. This book is encyclopedic in scope, incorporating extensive references for each condition, numerous diagrams and pictures, and a detailed analysis of the clinical disorders included in the differential diagnosis of each condition. The third edition builds upon this format to incorporate new discoveries about mechanisms of disease, new diagnostic modalities, advances in treatment in the field of pediatric neuro-ophthalmology, and updated neuroimaging figures. ​

Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team.Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites – for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches.Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT).New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section.Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes.Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors.Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current.Disease Site chapters feature updated information on disease management and outcomes.Thirty all-new anatomy drawings increase your visual understanding.Medicine eBook is accessible on a variety of devices.

The premier guide to Shonishin — Japanese Pediatric Acupuncture — now in a new editionNow in an expanded new edition, this user-friendly manual remains the foremost instructional reference for the application of Shonishin, or Japanese pediatric acupuncture. The book addresses the unique and often changing circumstances involved in the treatment of infants and children. It focuses on the crucial factors of patient comfort and dosage regulation throughout treatment by gently and painlessly pressing, tapping, scratching, rubbing, and stroking the skin without penetrating it. Stephen Birch, the world's leading authority in Japanese acupuncture and Shonishin, provides valuable clinical guidance and hands-on advice that can be easily integrated into everyday practice.The book begins by presenting the underlying principles and treatment tools used in Shonishin, and then goes on to cover root and symptomatic approaches and techniques, followed by details on how to manage a wide range of specific problems and diseases. More than 75 case histories from around the world present various treatment ideas, methods, and results for the featured condition.Highlights:More than 25 new clinical cases (over 75 cases total) offer useful insights and suggestions for daily practiceNew information on using Shonishin to treat headaches and emotional problems; combining Shonishin with other treatments, such as Bach flowers and Chinese herbal medicine; and using the techniques of Shonishin and the Meridian Therapy root treatmentCoverage of Shonishin for the management of a broad spectrum of illnesses and diseases, including respiratory and digestive ailments, ear infections, allergies, sleep problems, and many moreExercises throughout the book help readers improve their skill and check their techniqueMore than 150 precise illustrations complement and further clarify the textVideo footage of a workshop where the author demonstrates how to do Shonishin and shows real treatments bring concepts to life (accessed through Thieme's Media Center)With Shonishin: Japanese Pediatric Acupuncture, Second Edition, professionals and students in acupuncture, and pediatricians and physical therapists who use acupuncture, will learn from the master the art of non-inserted needling to treat children. This volume contains all of the information that practitioners need to understand Shonishin as a treatment option and refine their technique, and to instruct parents on how to regularly use Shonishin at home, thereby increasing the frequency of treatment.

Clinical neurophysiologic testing is an important component of evaluating patients with complaints that may be attributed to diseases of the central or peripheral nervous system. This classic volume in the Contemporary Neurology Series covers the basic concepts underlying each of the testing techniques and provides comprehensive descriptions of the methods and wide range of electrophysiologic testing available for patients with epilepsy, neuromuscular diseases, movement disorders, demyelinating diseases, sleep disorders, autonomic disorders and those undergoing orthopedic and neurosurgical procedures. This text details the role of each study, the interpretation of findings, and their application clinical problems. This text describes the multiple diagnostic procedures for diverse diseases of the neuromuscular system, including: electroencephalography (EEG); electromyography and nerve conduction studies; single fiber EMG; polysomnography; surface EMG patterns, blood pressure, pulse, sweat measures; vestibular function testing; deep brain stimulator physiology; and intraoperative monitoring. It is a practical textbook for neurologists, physiatrists and clinical neurophysiologists in clinical or research practice or in training. Key Features of the New Edition Include: 1. Fully updated chapters to reflect new research and techniques in clinical neurophysiology. 2. Updated images illustrating key elements of techniques and basic concepts. 3. Case examples for practical application.

Pain and the Conscious Brain brings together more than 30 international leaders from multiple fields to link the complex concept of pain to the equally complex notion of consciousness. Offering a clear, cutting-edge understanding of the brain mechanisms that generate the conscious experience of pain, this book scientifically addresses the difficult and chronic pains that often have no known physical cause and can defy comprehension in terms of current pain theories. Numerous tables, full-color figures, and up-to-date references highlight expert coverage of today's gradual paradigm shift from peripheral receptors to the intricacy of the brain and the experience of the self.

Injury to the anterior cruciate ligament (ACL) is common and typically affects young individuals; in particular, girls have higher rates of sustaining non-contact ACL injuries than boys when they engage in sports that involve jumping, pivoting, and changing direction. Multiple intrinsic and extrinsic risk factors for ACL injury have been identified, including anatomic variations, neuromuscular deficits, hormonal status and other related factors. Despite a lack of scientifically validated and published guidelines to help clinicians decide between conservative and surgical treatment, patient-specific criteria, such as age, pain, recurrent joint instability, desired level of activity, occupation and presence of potential concomitant injuries, should be considered. Neuromuscular training can reduce the risk of ACL injury, especially when combined with other strength training exercises. Chapter One in this book outlines the current state of knowledge regarding the risk factors, treatment and prevention of ACL injuries. Chapter Two provides is a better understanding of what associated factors are identified following ACL tear and explore the current understanding of the impact these have on treatment and subsequent outcome. The final chapter discusses surgical and rehabilitation concepts of matrix-induced autologous chondrocyte implantation in the treatment of knee articular cartilage defects.

The recent development of hypofractionated stereotactic radiation therapy (SRT), which calls for one to five fractions of high-dose radiation to be administered using special equipment, has resulted in the need for education on practice guidelines. Image-Guided Hypofractionated Stereotactic Radiosurgery: A Practical Approach to Guide Treatment of B

This comprehensive volume is widely regarded as the definitive practitioner resource and text in the field of biofeedback and applied psychophysiology. Leading experts cover basic concepts, assessment, instrumentation, clinical procedures, and professional issues. Chapters describe how traditional and cutting-edge methods are applied in treatment of a wide range of disorders, including headaches, temporomandibular disorders, essential hypertension, pelvic floor disorders, attention-deficit/hyperactivity disorder, tinnitus, and others. Applications for optimizing physical performance among artists and athletes are also reviewed. A wealth of information and empirical research is presented in an accessible style, including helpful glossaries. New to This Edition •Incorporates significant technological developments and new research areas. •Expanded focus on specialized applications, such as electroencephalographic (EEG) biofeedback/neurofeedback and heart rate variability biofeedback. •Chapters on surface electromyography, quantitative EEG, and consumer products. •Chapters on cognitive-behavioral therapy and relaxation training. •Chapters on additional clinical problems: anxiety disorders, asthma, work-related pain, traumatic brain injury, autism spectrum disorders, and substance use disorders.

¿Es el lenguaje el resultado exclusivamente del procesamiento de estímulos de carácter lingüístico por parte de un mecanismo de aprendizaje general? ¿O es consecuencia, por el contrario, de la actividad de un'órgano'cerebral que aparece recurrentemente durante el desarrollo por efecto de un programa innato que se pone en marcha desde antes del nacimiento? Y en todo caso, ¿cómo ha podido surgir desde el punto de vista evolutivo, toda vez que parece carecer de continuidad con otros sistemas de comunicación animales? En el presente libro, las siempre controvertidas cuestiones del innatismo lingüístico, de la estructura y el funcionamiento de la cognición humana, y de la evolución del lenguaje se abordan desde el punto de vista ciertamente inhabitual de la biología molecular, analizando de un modo particularmente detallado la arquitectura del programa de desarrollo (en gran parte de naturaleza genética) que parece intervenir en la organización y la actividad de los centros neuronales encargados del procesamiento lingüístico. Buena parte del libro se dedica, consecuentemente, a la caracterización estructural y funcional de los genes que forman parte de dicho programa, prestando una especial atención a la naturaleza de los trastornos de índole lingüística causados por su mutación. Pero del mismo modo, y con objeto de reevaluar críticamente las diversas hipótesis que, sobre el origen y la evolución del lenguaje, se han venido realizando hasta la fecha, se examina también la historia evolutiva de aquellos genes que parecen haber desempeñado un papel relevante en la aparición del lenguaje en términos filogenéticos. A pesar de todo, la caracterización del lenguaje que surge de este tipo de análisis biológico del lenguaje casa satisfactoriamente con algunas de las propuestas más recientes que, sobre la naturaleza y la evolución del lenguaje, se han desarrollado en el ámbito de la propia Lingüística, en particular, con las derivadas del Programa Minimalista chomskyano, que conciben esta facultad exclusivamente humana como una consecuencia de la novedosa puesta en contacto de sistemas motrices y cognitivos que contarían con una historia evolutiva más dilatada.

We possess as a cognitively aware species a high degree of function localization, but we still subscribe to the notion consistent with the model that dysfunction or damage to specific regions of the brain and nervous system may result in specific damage and deficits in behavior and function of individuals. Unfortunately, that is not enough to explain the capacity for plasticity, regeneration, spontaneous recovery, and optimization in neurological terms, and certainly not in its translation in clinical rehabilitation. Among the difficulties we face in the application of rehabilitation science in practice, the need to understand how the nervous system functions is less than understanding how it recovers from dysfunction, how we can effectively evaluate function, dysfunction and recovery, and how to provide a rational basis for making economic decisions about which method or methodology to invest. A neuroanatomical conceptualization is a not an option for rehabilitation practice. It is important to understand that what we are really attempting to achieve both in rehabilitation as well as in understanding the neurological basis of cognitive and motor improvement after trauma or stroke is not which brain area controls a given cognitive function, but how efficiently brain regions cooperate with each other and how novel connectivities may develop.

Dit boek bevat geen kant-en-klare recepten voor pijnbestrijding, maar stelt primair het denken over pijn aan de orde, vanuit de overtuiging dat in de klinische praktijk het denken steeds aan het handelen vooraf dient te gaan. Pijn, vanuit een neurowetenschappelijk perspectief is het derde deel van de vierdelige serie ´Toegepaste neurowetenschappen´. Inzichten over pijn zijn de laatste vijftig jaren herhaaldelijk ingrijpend gewijzigd. Pijn is lang niet altijd een direct gevolg van weefselschade, maar is een uiterst variabele en flexibele gewaarwording die meestal van veel factoren tegelijk afhangt. Het vaak impliciete uitgangspunt ´pijn is vervelend en moet dus bestreden worden´ is achterhaald. In plaats daarvan komt een zorgvuldige analyse van de zin van pijn. Pijn kan een signaal zijn voor onraad in de ruimste zin van het woord, maar pijn kan ook een doel hebben: het dwingt een zinvolle gedragsverandering af. Het domweg bestrijden van pijnkan daarom riskant zijn. Filosofische, psychologische, fysiologische en neurologische benaderingen sluiten vaak goed op elkaar aan. De neurowetenschappen zorgen voor de stevige brug tussen deze invalshoeken. In het boek komt pijn in vijf te onderscheiden gedeelten aan de orde. 1 Concepten over pijn: reflecties over de zin van pijn, de vele dimensies van pijn, de oorsprong van pijn. 2 Neurowetenschappen. De rol van het perifere (pijnvezels) en het centrale zenuwstelsel (pijn in het brein) komen uitvoerig aan de orde. Belangrijke nieuwe ontwikkelingen hebben plaatsgevonden betreffende de hersengebieden die bij pijn betrokken zijn, plastische veranderingen en de rol van pijnmodulerende systemen. 3 Psychologie. In de praktijk wordt ook nu nog vaak ervan uitgegaan dat chronische pijn een somatische of psychische oorzaak heeft: het'dualistische simplisme'. Dit boek tracht een nuancering aan te brengen door verschillende psychologische denkmodellen te presenteren: de psychofysiologische, deoperante en de cognitieve verklaringswijzen voor pijn. 4 Pijnsyndromen: viscerogene pijn, diverse neurogene pijnsyndromen (o.a. CRPS en fantoompijn). Nieuwe verklaringsmodellen voor chronische pijn worden gepresenteerd: neurale reorganisatie en sensitisatie. 5 Evaluatie en behandeling. Hoe kan pijn in kaart worden gebracht en wat kan de betekenis hiervan zijn voor de praktijk? Argumenten op grond waarvan een placebo- en nocebo-effecten wordt benadrukt. Speciale aandacht wordt gegeven aan neuromodulatietherapieën: pijnbehandeling door prikkeling zoals acupunctuur, vibratie, muziek en TENS. Afsluitend worden enkele adviezen gegeven voor een pijnanalyse in de praktijk volgens de'empirische cyclus': het'denken over pijn'wordt verwerkt in het klinisch handelen.Het boek kan een nuttige functie hebben in diverse opleidingen (medisch, paramedisch, psychologie). Het kan ook worden gebruikt als gemeenschappelijk startpunt bij het vormen van een interdisciplinair pijnteam. Vooral dan is een zekere consensus wat betreft uitgangspunten en visie over pijn van belang.

This book focuses on the features of pelvic pain in the different cancer diseases, the pain assessment tools, as well as the pharmacological and non-pharmacological approaches. Pelvic cancer pain is a common and debilitating symptom, and pain control is a one among the main therapeutic goals throughout the duration of the disease. Because pelvic cancer pain due to primitive cancer, recurrence or metastasis is a complex clinical pathology, no single technique is often guaranteed to produce a complete pain relief. Thus, there are many treatment options, but in most cases a correct approach to pain control should be provided by a multidisciplinary team under the responsibility of a pain specialist coordinating several professionals. This book will aid several figures of practitioners, like anesthesiologists, oncologists or surgeons, in making the correct decisions in individual patients affected by cancer pain due to pelvic diseases.