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Seit dem Erscheinen der 1. Auflage dieses Lehrbuches zur Neurodermitis sind beträchtliche Fortschritte hinsichtlich der Erforschung der Krankheitsentstehung und der Entwicklung neuer Therapien erzielt worden. Die mittlerweile vorliegende 4. Auflage berücksichtigt diesen Progress und widmet sich bei der Vermittlung des komplexen therapeutischen Vorgehens neben den verschiedenen bisherigen Optionen auch neuen Medikamenten zur systemischen Therapie. Die Auswahl der Themen und deren Gewichtung in diesem Buch beruht dabei u.a. auf den langjährigen Erfahrungen aus Neurodermitisschulungen. Auch den psychosozialen Komponenten der Krankheitsbewältigung und -anpassung sowie der Edukation der Betroffenen wird ein entsprechender Stellenwert beigemessen. Dieses Buch ist erneut ein bewährter Leitfaden für Patienten und Ärzte gleichermaßen, der alle wichtigen Facetten der Erkrankung darstellt und vertieft.

This book is a concise practical guide designed to facilitate the clinical decision-making process in the management of adolescent skin disease. Dermatologists and general pediatricians who offer primary care to adolescents must be knowledgeable in managing dermatological problems, and this title provides insightful reviews of a number of common and rare dermatologic cases. Clinical cases are a key component in modern medical education, assisting the trainee or recertifying clinician to work through unusual scenarios using best practice techniques. Adolescent dermatology is a particularly important discipline in this regard, since it is a highly visual subject requiring the reader to describe often very subtle differences in the presentation of patients and define accurately the diagnostic and management criteria on which to base their clinical decision-making. Clinical Cases in Adolescent Dermatology concisely covers how to approach diagnosingand managing patients from 12 through 18 years of age. Each chapter focuses on a particular case and emphasizes how to make an appropriate choice when deciding which diagnostic tool or management strategy would be most suitable. Potential complications are detailed and management tips provided to enable the reader to develop a deep understanding of how approach the care of these patients within their day-to-day clinical practice. This book therefore represents an ideal up-to-date resource for all practitioners who encounter the condition as part of their everyday practice.

A great deal of knowledge about eosinophilic lung diseases has been gained in the last few years, but unanswered questions concerning eosinophil biology still remain. It is in this context that this Monograph was developed. Broad in scope, the book bases its approach to the management of eosinophilic lung diseases on a fundamental understanding of eosinophil biology in health and disease. State-of-the-art reviews written by world-leading authorities and up-and-coming stars in the field take the reader on a journey through the different eosinophilic lung diseases. This Monograph will ensure the practicing clinician is better equipped to recognise and treat patients with eosinophilia, as well as appreciate the advances coming in the near future.

All the chapters have been written by authors who are experts in their relevant areas of interest. This endeavor hopes to present to the Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) members, recent high-quality publications and literature in a concise and an easy readable format.

This book identifies the broad scope of dermatological conditions in patients with scalp disorders. Scalp disorders can be associated with various conditions such as inflammatory, neoplastic and systemic diseases. Patient history and physical examination significantly narrow the differential diagnosis, but in doubtful cases trichoscopy or scalp biopsy is needed to establish correct diagnosis. Treatment of scalp diseases varies from topical through intralesional to systemic options, dependent from type and severity of the disease as well as coexisted conditions. Clinical cases are the key component in modern medical education, assisting the trainee or recertifying clinician to work through unusual cases using best practice techniques. Clinical Cases in Scalp Disorders illustrates clinical features and discuss diagnostic and therapeutic process of both common and unusual conditions. It provides a practical case-based guide in the management of patientswith scalp diseases and is ideal for both board-certified dermatologists and dermatologists in training.

Biologic therapy is a treatment that strives to modulate a patient's immune system to fight a given disease. In psoriasis, a skin disorder that is partly caused by a dysregulated immune system resulting in well-demarcated red areas of the skin with white scales, biologic therapy has the potential to vastly improve upon patient outcomes by minimizing the symptoms of this disease while maximizing the safety profile of the therapy. This book offers an up-to-date and comprehensive review on biologic therapy for the treatment of psoriasis. With over 10 FDA approved biologic agents for psoriasis (with more in the pipeline), confusion exists among providers regarding which agent is best for a particular patient. Chapters cover all FDA approved psoriasis biologic agents (including pipeline agents) for use in pediatric, adult, and geriatric patients. This book is unique in that it will not only cover cutting edge treatment principles based on the latest research, it will also be one of the most comprehensive reviews of psoriasis biologics in the COVID-19 era. Biologic Therapy for Psoriasis is a must-have resource for board certified dermatologists and rheumatologists, dermatology and rheumatology residents and fellows, dermatology physician assistants, nurse practitioners and medical students. The ultimate goal of this book is to improve patient care by making the busy practicing dermatology provider more adept with these particular therapies.

Die Rosazea ist eine entzündliche Hauterkrankung, die mit einer erheblichen Einschränkung der Lebensqualität einher geht. In Deutschland sind etwa fünf Prozent der Erwachsenen davon betroffen. Oft sind Stigmatisierungen und subjektiver Leidensdruck die wesentlichen Faktoren, welche die Patienten in die Praxis des Hautarztes führen. Und auch wenn die Rosazea als chronische Erkrankung heute noch nicht vollständig heilbar ist, lassen sich die Symptome meist gut behandeln. Auch können Faktoren, die die Gesichtsrötungen begünstigen, bewusst vermieden werden, Hautpflege und Sonnenschutz die Beschwerden lindern. Zudem können zahlreiche verschiedene Medikamente äußerlich und/oder systemisch angewendet werden. Die Neuauflage der vorliegenden Monographie ist von den Autoren auf den aktuellsten Stand des Wissens gebracht worden und stellt erneut einen aktuellen Leitfaden für die sinnvolle und wirksame Differentialtherapie in der Praxis dar.

This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists. The opening, general section discusses basics such as clinical manifestations, histopathology, mechanisms, risk factors, drug hypersensitivity in particular populations, and the full range of diagnostic methods. The second part of the book provides concise information on the most important drug classes and guides the reader on how to proceed when patients present with a suspected reaction. For each drug class, the current level of evidence for use of the different diagnostic tools, including skin tests, provocation tests, and in vitro tests, is clarified, and management options, outlined. The inclusion of helpful tables and algorithms is designed to aid in decision making. Drug hypersensitivityis among the more complex allergological issues, and this book will meet the needs of general practitioners, internists, and specialists.

Dieses Referenzwerk bietet dem Allgemeinpädiater, dem angehenden Facharzt und dem (Kinder-)Rheumatologen umfassende Antworten auf alle Fragen der Entstehung, Diagnostik und Therapie von rheumatologischen Erkrankungen bei Kindern und Jugendlichen. Der spezielle Fokus liegt auf der Relevanz und dem Nutzen im Alltag des Pädiaters. Die genauen Angaben zu Therapieempfehlungen und Hinweise zur Evidenz der Therapieverfahren bürgen für einen zuverlässigen und schnellen Behandlungserfolg. Fundierte „State-of-the-Art“-Kinderrheumatologie, praxisbezogen aufbereitet. Ideal zum Nachschlagen für fundiertes Wissen über die Krankheiten, die verwendeten Medikamente und ihre Wirkung im kindlichen Organismus.

Common Pediatric Diseases: An Updated Review informs the reader about common diseases in children that are encountered by pediatricians and family physicians. Each of the 14 chapters in the volume presents updated information for readers with the aim to give them a current perspective on the topic. This book is a handy and practical compendium for medical students and healthcare professionals involved in general practice and pediatric clinics.The text starts with a quick introduction to pediatric diseases, before progressing towards specific diseases in children. The list of topics in this book includes pediatric rheumatological diseases, common oral diseases, pediatric metabolic syndromes, pediatric epilepsy syndromes, pediatric demyelinating disorder, genetic epileptic encephalopathies (with an algorithmic diagnostic approach), Henoch-Sch amp;amp;ouml;nlein purpura, atopic dermatitis, childhood-onset systemic lupus erythematosus, Severe Combined Immunodeficiency, PFAPA, aphthous stomatitis, pharyngitis, cervical adenitis syndrome and pediatric hepatoblastoma.[Series Intro]Updates on Pediatric Health and Disease is a comprehensive series of books on infant and adolescent health and diseases. The series features volumes that update readers on current understanding in basic information and advanced clinical practice in pediatric medicine. Neonatology as well as different diseases in all subspecialties of pediatrics, including allergy and immunology, cardiology, endocrinology, gastroenterology, hematology, infectious diseases, nephrology, oncology, pulmonology, rheumatology, neurology, psychiatry and dermatology are represented in each volume.

To put it in a nutshell, the book – Postgraduate Dermatology is an inspiring, complete, comprehensive and a crispy recipe book on dermatology for the postgraduate students- easy to digest, recall or ruminate to remember the subject. This is just not an examination purpose notebook, but a collective wisdom of key academic opinion leaders bejeweled the extensive and priceless clinical arsenal of the authors.

Com muita satisfação, percorro os olhos sobre os capítulos deste volume da Acta Medica. Penso que eles trazem aspectos da prática diagnóstica e terapêutica para problemas de saúde prevalentes no âmbito da APS e também retratam uma preocupação de abordar temas relevantes e importantes associados aos adoecimentos na atualidade, como os que abordam a Violência, o Suicídio, a Obesidade, os Transtornos do Déficit de Atenção, a Desmedicalização, entre outros. Avalio que a leitura destes capítulos é de grande utilidade para todos que querem desenvolver uma prática médica mais adequada, não só para os que atuam na APS, mas para todos e todas que desejam ampliar seu conhecimento e sua compreensão para problemas de saúde da atualidade.'

This book covers dermatological and related esthetic concerns specific to female patients. Since knowing what's normal is as important as knowing what's not, first chapters covers physiological differences in the skin of women and the changes during puberty, pregnancy, and menopause. Certain commonly encountered dermatoses are more frequent in females – chronic telogen effluvium, rosacea, perioral dermatitis, pigmented contact (cosmetic) dermatitis, etc., which are explained in a more focused manner. Dermatoses exclusive to females involving the vulva is discussed at length. These include common papulosquamous conditions such as psoriasis, lichen planus, and lichen sclerosus as well as the uncommon but challenging plasma cell vulvitis. Breast dermatoses also are predominantly encountered in women and are described in detail in this book. Importantly, the safety of drugs and biologics in pregnancy and lactation have been covered too. One section is dedicated to the emotional and psychological burden of skin disease in women and certain disorders requiring psychiatric intervention such as obsessive-compulsive disorder (trichotillomania, trichotemnomania) and body dysmorphic disorder. Furthermore, commonly used cosmeceuticals and frequently performed esthetic procedures such as chemical peels, botulinum toxin, and soft tissue augmentation (fillers) are well explained. Skin diseases in females can cause a significant emotional and psychological impact that can sometimes be more serious than the physical impact. There is a paucity of comprehensive published literature in both journal and books and this book aims to fill that gap. This book is meant as a resource for dermatology residents and trainees, practitioners, and teachers.

This book brings together world-famous acne researchers and specialists to compile a source of comprehensive, state-of-the-art information for management of acne. It examines acne as a chronic skin disease from pathogenesis to treatment. The book covers the clinical aspects of acne, topical treatments, light therapies, environmental factors and more alongside real patient photos from around the world. Treatments that chapters explore include photodynamic therapy and topical retinoids. In addition to genetic and hormonal causes of acne, chapters also include discussions on the connections between acne and diet, and acne and environmental factors. International contributors make this text unique in that it can focus solely on acne but also include international factors. Throughout the text, authors present the most up-to-date knowledge of acne pathophysiology, clinical features, differential diagnosis, treatment, and more.Pathophysiology, in particular, includes information on bacteria, immunity, endocrinologic factors, various deteriorating factors and environmental factors. As for clinical features, adult acne, differences in clinical patterns by region and race, and acne fulminans are covered. Regarding treatment, the latest knowledge on existing treatments or treatment methods, new drugs, and core outcome measures are mentioned. Acne: Current Concepts and Management is written for the dermatologist community from resident to researcher to privately practicing clinician.

This extensively revised second edition provides an up-to-date and highly informative textbook on psoriasis. The understanding of the mechanisms behind the disease and the available treatment options have continued to develop rapidly in recent times, with this vital resource covering the latest in these management options, including targeted T-cell therapy, the use of immunomodulators, systemic therapies, and ultraviolet and laser therapy. In addition, it provides a detailed overview of the pathophysiology, comorbidities, epidemiology and triggers of the disease. Advances in Psoriasis: A Multisystemic Guide extensively details the scientific basis and practice management of psoriasis. It is therefore a vital resource for practicing and trainee dermatologists looking to develop their clinical knowledge of how to manage and treat these patients.

• An initiative of Atopic Dermatitis Centres of Reference and Excellence (ADCARE) Global Allergy and Asthma European Network (GA2LEN).

This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment.Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa.Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.

Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more. Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease. - Provides updated and extensive review articles that focus on different aspects of pancreatic cell biology - Offers a wide range of perspectives for basic and translational research - Includes original figures that help readers understand the complex pathways involved in cell function in homeostasis and under pathogenic conditions

A comprehensive guide, Women's Health in IBD: The Spectrum of Care From Birth to Adulthood will help providers approach the specific issues that women with inflammatory bowel disease (IBD) face throughout their lifetimes. This book will better equip providers to counsel and support women of all ages with IBD.In Women's Health in IBD, Drs. Bincy P. Abraham, Sunanda V. Kane, and Kerri L. Glassner focus on the unique aspects of care for women with IBD. Half of the IBD patient population is female. As we understand more about gender and sex differences in terms of genetics, physiology, and medical care, it is important to consider these factors between men and women to personalize their care.This book encompasses the entire life span of the female IBD patient through birth, adolescence, pregnancy, menopause, and older adult years. Each chapter includes discussions of medications, treatment plans, and common questions or controversies on important topics in IBD such as: Transitioning from pediatric to adult care Diet and nutrition Mental health Health maintenance Family planning Pregnancy and breastfeeding Menopause Concomitant irritable bowel syndrome Women's Health in IBD: The Spectrum of Care From Birth to Adulthood is an essential text that will help anyone who treats women with IBD, offering practical tools and takeaways for point of care and beyond.

This book represents a simple, practical resource for all healthcare professionals working with dermatological patients with psychological aspects to their disease. The emphasis is on effective guidance rather than exhaustive case reviews, providing readers with a manual on the appropriate way to approach management of the patient in each case. Comprehensive in coverage, but concise in its delivery of information, Psychodermatology in Clinical Practice presents an idealized approach to management of psychodermatology patients within a global perspective, and provides practical tools to aid assessment of patients and in the decision-making process. It is suitable for dermatologists, psychiatrists and psychologists, dermatology nursing staff, primary care physicians and pediatricians.

The incidence of skin cancer continues to rise, as do the challenges physicians face in treating the growing population of skin cancer patients. Skin Cancer Management: A Practical Approach, 2nd edition addresses the spectrum of skin cancers from the precancerous to the inoperable. In this revised and updated edition, a wide selection of medical treatments and surgical procedures are described in detail and supplemented with an abundance of full-color figures. Numerous case studies help to illustrate the various techniques.

Real-life primary care case studies• from more than 50 primary care providers, including physician assistants, nurse practitioners, and physicians!101 Primary Care Case Studies offers real-life patient scenarios and critical thinking exercises to help you work through a patient's chief complaint. Through narrative case studies, you will determine how best to diagnose, treat, and manage your patient based on the history of present illness, review of systems, relevant history, and physical examination findings. This workbook will ask probing questions to help you determine differential and most likely diagnoses, diagnostic tests to order, and appropriate patient management strategies using relevant and timely references to support your decisions. The organization of each case study simulates the patient care journey from chief complaint to outcome.Serving as a virtual clinical preceptor, this workbook can be used independently or in a classroom setting. It is accompanied by a robust online student supplement that provides answers to all questions, real outcomes of the cases, and valuable personal insights from the authors on how the patient was successfully managed. Not only will this workbook help you work through patient cases clinically, it will also share important, but often overlooked, bedside manner skills needed to successfully communicate with and care for your patients.Covering conditions across all organ systems and across the lifespan, this workbook is organized by chief complaint, providing an authentic perspective on what to expect in the patient care environment. It even includes information on pathophysiology and how to use ICD-10 and CPT (E/M) codes in your documentation. The book uniquely weaves together both the science and art of medicine by including personal insights into quality and compassionate care.Key FeaturesProvides real-life patient cases from an interprofessional author team of physician assistants, nurse practitioners, and physiciansUses a templated case study design and critical thinking exercises to help you methodically work through various patient scenariosTeaches clinical and bedside manner skills imperative for delivering quality patient careCovers patients across the lifespan, including pediatric, adolescent, adult, and geriatric populationsOffers additional insight on patient education, medical and legal concerns, and interprofessional collaborationIncludes a robust online student supplement with valuable insights from the authors on how they successfully managed the casesProvides instructors with a table of contents that is filterable by chief complaint, diagnosis, patient population, and organ system•Details changed to protect patient information.

Written by global experts in the field of chemical- and drug-related ocular problems, Drug-Induced Ocular Side Effects, 8th Edition, provides need-to-know information on all aspects of ocular toxicology in one concise reference. This best-selling, user-friendly resource features a templated format, numerous full-color illustrations, and sweeping content updates throughout – all designed to eliminate uncertainty and ensure accurate diagnosis and treatment guidance. - Provides comprehensive coverage of drugs'generic and trade names, primary uses, ocular and systemic side effects, and clinical significance. - Features a unique side effect index, a new concise paperback format for portability, and clinical photos of ocular symptoms of adverse drug reactions. - Covers dozens of new drugs used in the U.S. and internationally, as well as extensive updates to drug registry information to ensure access to the latest data. - Includes expanded sections on how to follow patients with visual adverse drug reactions to chloroquine, hydroxychloroquine, isotretinoin, ethambutol, and more. Guidelines can be copied to use as patient handouts. - Offers extensive discussions of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics. - Provides the WHO classification system to help you determine whether a particular side effect is certain, probable, or likely to occur. - Ideal for ophthalmologists, optometrists, and busy clinicians in primary care, emergency medicine, and more – anyone who needs quick, on-the-spot consultation on ocular toxicology. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This latest book in the Clinical Cases in Dermatology series presents a variety of cases of pruritus. A clear easy-to-follow chapter structure throughout the work enables the reader to develop a thorough understanding of the content covered in each case. An emphasis is placed on key features that distinguish pruritus from other conditions to ensure the reader develops their diagnostic skills. Practically applicable guidance on how to appropriately manage the disorder to assist the reader in the clinical decision-making process is also provided. Clinical Cases in Pruritus is a concise practically applicable resource detailing how to diagnose and manage pruritus in a variety of scenarios. Therefore, it is of interest to practicing and trainee dermatologists seeking a concise up-to-date resource on the topic.

The Public Relations Handbook, 6th edition provides an engaging, in-depth exploration of the dynamic and ever-evolving public relations industry. Split into four parts exploring key conceptual themes in public relations, the book offers an overview of topics including strategic public relations, politics and the media; media relations in the social media age; strategic communication management; public relations engagement in the not-for-profit sector; activism and public relations; and the effects of globalisation and technology on the field. Featuring wide-ranging contributions from key figures in the PR profession, this new edition presents fresh views on corporate social responsibility, public relations and politics, corporate communication, globalisation, not-for-profit, financial and public sector public relations. The book also includes a discussion of key critical themes in public relations research and exploratory case studies of PR strategies in a variety of institutions, including Extinction Rebellion, Queen Margaret University, Mettis Aerospace, and Battersea Cats'and Dogs'Home. Containing student-friendly features including clear chapter aims, analytical discussion questions, and key further reading throughout the text, The Public Relations Handbook is an ideal resource for students of public relations, corporate and strategic communications, and media studies.

Der Arzneiverordnungs-Report ist seit 1985 eine gemeinsame Publikation von Autoren aus Pharmakologie, Klinik, Praxis, Gesundheitsökonomie und Krankenversicherung. Basis sind die Verordnungsdaten von Arzneimitteln für ambulante Patienten der gesetzlichen Krankenversicherung (GKV). Datenbasis des Jahres 2020 sind ca. 820 Mio. Verordnungen von 150.363 Vertragsärzten und 62.876 Vertragszahnärzten für 73,4 Mio. GKV-Versicherte. Die allgemeine Verordnungs- und Marktentwicklung wird in 6 Kapiteln behandelt, in denen u.a. neue Arzneimittel des Jahres 2020, die Kosten-Nutzen-Analyse von onkologischen Arzneimitteln, Marktsteuerungsmechanismen und Preise von Biologika bzw. Biosimilars sowie die Klassifizierung von Arzneistoffgruppen diskutiert werden.Die Nettokosten für Arzneimittel in der GKV sind 2020 weiter um 5% auf rund 46 Mrd. € gestiegen, vor allem durch neue, hochpreisige Patentarzneimittel. Hauptkostentreiber waren Onkologika (9,5 Mrd. €, + 12,4%)und Antidiabetika (2,8 Mrd. €, + 16,8%). Ein wesentlicher Grund für die Kostenprobleme ist der seit Jahren beobachtete Anstieg der Jahrestherapiekosten neu eingeführter Arzneimittel. Dieser Trend zu hochpreisigen Patentarzneimitteln ist durch das Arzneimittelmarktneuordnungsgesetz (AMNOG) sogar 10 Jahre nach seiner Einführung nicht genügend abgeschwächt worden, auch wenn mit der Vereinbarung von Erstattungsbeträgen 2020 insgesamt 3,7 Mrd. € an Einsparungen erzielt werden konnten.

This book is a comprehensive, practical guide to the latest developments in the understanding and management of atopic dermatitis. Detailed information is provided on age-specific clinical symptoms, features, and diagnostic methods. Current theories on the pathogenesis of atopic dermatitis are closely examined, with attention to the roles played by genetic, allergic, immunologic, and skin barrier dysfunctions. In the second half of the book, the scientific background to and the practical use of the full range of treatment methods are described, covering topical agents, systemic agents, phototherapy, allergen-specific immunotherapy, and the most recently developed biologics and small molecules. This textbook will be an excellent guide to diagnosis and treatment for not only dermatologists but also practitioners in allergy and general medicine, including pediatricians, allergists, and primary care physicians. In addition, it will be of value for all scientists interested in developing new drugs for atopic dermatitis.

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-6, IL-7, IL-10, IL-12, IL-22, IL-23, and IL-24 signaling.Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins – Part B updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Real-world evidence (RWE) has been at the forefront of pharmaceutical innovations. It plays an important role in transforming drug development from a process aimed at meeting regulatory expectations to an operating model that leverages data from disparate sources to aid business, regulatory, and healthcare decision making. Despite its many benefits, there is no single book systematically covering the latest development in the field.Written specifically for pharmaceutical practitioners, Real-World Evidence in Drug Development and Evaluation, presents a wide range of RWE applications throughout the lifecycle of drug product development. With contributions from experienced researchers in the pharmaceutical industry, the book discusses at length RWE opportunities, challenges, and solutions.Features Provides the first book and a single source of information on RWE in drug development Covers a broad array of topics on outcomes- and value-based RWE assessments Demonstrates proper Bayesian application and causal inference for real-world data (RWD) Presents real-world use cases to illustrate the use of advanced analytics and statistical methods to generate insights Offers a balanced discussion of practical RWE issues at hand and technical solutions suitable for practitioners with limited data science expertise

This book serves as a concise text on nail diseases and disorders, offering the most up to date information available from internationally recognized speakers and authors. This comprehensive guide examines a multitude of nail disease types manifestations, treatments, and complications. Chapters delve into specific disorders such as yellow nail syndrome, psoriasis, lichen planus, and brittle nails. Notable treatments covered include advances in MRI, anti-neoplastic drugs and ultrasound imaging. The book also features discussions on unique topics, such as the convergence of orthopedics and onychology in nail disease treatment, as well as treatment complications faced by distinct demographics. Going beyond basics and diving right into the heart of various diseases and disorders, Advances in Nail Disease and Management will serve to aid experienced dermatologists looking for advanced expertise information.

Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by chemically adding phosphate groups to them. New chapters in this release include Transport Proteins and AMPs: Implications in Human Disease, Protein kinase CK2 inhibition as a pharmacological strategy, Emerging role of Protein kinase in diabetes mellitus: From Mechanism to therapy, Dual Roles of ATP-binding site in Protein Kinases: Orthosteric inhibition and Allosteric Regulation, Pseudokinases in drug discovery and development: progress, challenges and future prospects, Comparison of knowledge-based vs. combinatorial peptide library approaches for the identification of protein kinase substrates, and more. - Contains timely chapters written by well-renown authorities in their field - Includes a number of high-quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students - Integrates experimental and computational methods for studying the role of protein kinases in different diseases, along with sections on the design of suitable protein kinase inhibitors for use in the treatment of patients

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Make the right drug therapy decisions with the definitive guide to pharmacotherapy principles applied in everyday practice Sub Head: Study companion to DiPiro's Pharmacotherapy: A Pathophysiologic Approach, 11th Edition Packed with 157 patient cases, Pharmacotherapy Casebook: A Patient-Focused Approach builds your problem-solving and decision-making skills, so you can identify and resolve the most common drug therapy challenges you'll encounter in daily practice. Its case-based approach is also ideal for PharmD, Nurse Practitioner, and other allied health courses. Providing a consistent, practical approach, this authoritative guide delivers everything you need to master patient communication, care plan development, and documenting interventions. Case chapters are organized into system sections that correspond to those of the companion textbook. Sharpen your ability to: • Identify actual or potential drug therapy problems • Determine the desired therapeutic outcome • Evaluate therapeutic alternatives • Design an optimal individualized pharmacotherapeutic plan • Evaluate the therapeutic outcome • Provide patient education • Communicate and implement the therapeutic plan Develop expertise in pharmacotherapy decision making with: • Realistic patient presentations that include medial history, physical examination, and laboratory data, followed by a series of questions using a systematic, problem-solving approach • A broad range of cases—from a single disease state to multiple disease states and drug-related problems • Expert coverage that integrates the biomedical and pharmaceutical sciences with therapeutics • Appendices containing sample answer to several cases and valuable information on medical abbreviations, laboratory tests, mathematical conversion factors, and anthropometrics

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. 25+ additional chapters available online! The classic guide to driving optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines Presented in full color, Pharmacotherapy: A Pathophysiologic Approach, 11th Edition helps you deliver the highest-quality patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. It takes you beyond drug indications and dosages, showing how to properly select, administer, and monitor drugs—everything you need to provide safe, effective drug therapy across all therapeutic categories. With all-new monitoring tables and authoritative content from 300 expert contributors, this new edition has been fully updated to reflect the latest evidence-based information and recommendations. You'll find Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy. Why Pharmacotherapy: A Pathophysiologic Approach is perfect for students, pharmacists, and other healthcare providers: • All chapters provide the most current, reliable, and relevant information available. • Key concepts kick off every chapter. • Clinical Presentation Tables summarize disease signs and symptoms. • The majority of sections include personalized pharmacotherapy content. • Clinical Controversies Boxes clarify the most complex drug therapy issues you'll face. • Diagnostic flow diagrams, treatment algorithms, dosing recommendations, and monitoring approaches have been updated in full color to distinguish treatment pathways. • Most disease-oriented chapters are enhanced by updated evidence-based treatment guidelines, which often include ratings of the level of evidence to support key therapeutic approaches. • Instructors who adopt this text are eligible for a PowerPoint presentation of all images and answers to Self-Assessment Questions! The most trusted guide of its kind for decades, Pharmacotherapy: A Pathophysiologic Approach is the go-to text for students and practitioners seeking clear, objective coverage of core pathophysiologic and therapeutic elements.

A consummate classic with a fresh approach to pediatric dermatology Children's skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.

『WHAT'S NEW in 皮膚科学 2020-2021』をお届けします。前回の2018-2019から早くも2年が経過しました。私は編者として全原稿を読ませていただいています。普段結構アンテナは張っているつもりですが、それでもこのあっという間の2年の間に知らなかったことや、ちょっと噂には聞いていたがしっかり調べたことがなかったこと、古い知識のままアップデートできていなかったことなどがたくさん出てきました。つまり、医学の進歩が早い現在、個人の努力では情報収集に限界があるということです。もちろんすべての領域について詳細に知っている必要はありませんし、そんなことは困難ですが、頭の片隅にちょっと置いてあれば、診療しながら気がつくことができ、自分で詳しく調べたり、専門家に相談したりすることができます。一方、まったく知らないと見逃してしまいます。少し知っているのとまったく知らないのとは大きな違いです。本書は先生方の頭の中に新しい知識をコンパクトに補充するのをお手伝いするものです。そのためには、前版の前書きでも書きましたが書きましたが,通読していただいてこそ価値があります。調べ物用ではありませんのでご注意ください。 （常深祐一郎「序文」より抜粋） 『WHAT'S NEW in 皮膚科学』を初めて2016-2017で担当し、この度から、編集業務を宮地良樹先生から引継ぎました。当時、初めての編集業務を宮地先生と行いました。その際、いかに宮地先生が手際よく、そして大所高所から的確に指示されるかを目の当たりにしました。今回、常深先生という素晴らしいパートナーとともに編集をフレッシュな立場から再度行うことができました。2020-2021では宮地先生も含めて3人で珠玉のテーマを選ぶことができたと自負致しております。これを機に宮地先生は勇退されるとのことです。しかしながら、横目にみますと『最新キーワードで読み解く ALL About 皮膚科学』という本があるではないですか！コンセプト的にも似ています。これは宮地先生から常深先生と私への挑戦状かもしれません。次回、2022-2023では常深先生とともに『ALL About 皮膚科学』と切磋琢磨しながらより良い最高の「What's New」を目指していこうと思います。期待してお待ちください！それでは珠玉の逸品をお試しあれ。 （鶴田大輔「序文」より抜粋）

Providing a solid foundation in clinical medicine for optometrists and optometry students, Clinical Medicine for Optometrists covers the systemic medical conditions that have serious impacts on ocular health and function, as well as the ocular exam findings that may be an early indication of significant systemic disease. This unique text explains important medical considerations for optometric practice, meeting the needs of clinical medicine courses in optometry programs, and also serving as a practical reference for optometrists in practice.

A Doody's Core Title for 2015!Principles of Athletic Training: A Competency-Based Approach is designed to be used by athletic trainers in courses concerned with the scientific, evidence-based and clinical foundations of athletic training and sports medicine. The text leads the student from general foundations to specific concepts relative to injury prevention, evaluation, management, and rehabilitation. As the student progresses from beginning to end, he or she will understand the complexities of the profession of athletic training. An over-arching goal of the text is to make certain that each and every one of the educational competencies identified by the Education Council is specifically covered. After using this text the student should be able to apply the appropriate techniques and concepts in the day-to-day performance of his or her job as an athletic trainer.McGraw-Hill Connect® is a subscription-based learning service accessible online through your personal computer or tablet. Choose this option if your instructor will require Connect to be used in the course. Your subscription to Connect includes the following:• SmartBook® - an adaptive digital version of the course textbook that personalizes your reading experience based on how well you are learning the content.• Access to your instructor's homework assignments, quizzes, syllabus, notes, reminders, and other important files for the course.• Progress dashboards that quickly show how you are performing on your assignments and tips for improvement.• The option to purchase (for a small fee) a print version of the book. This binder-ready, loose-leaf version includes free shipping.Complete system requirements to use Connect can be found here: http://www.mheducation.com/highered/platforms/connect/training-support-students.html

Atopic dermatitis is a chronic inflammatory skin disease that is characterized by xerosis, eczema lesions with skin barrier defects, and severe itch. This compilation describes recent advances in our understanding of intractable itch mechanisms and the development of antipruritic therapies in in this condition. Additionally, the authors summarize the current developments in understanding the comorbidities of atopic dermatitis. Insight into various emerging therapies along with currently approved treatments is provided. Some proposed interventions are presented regarding the population group that can benefit the most according to the severity of the symptoms, the mechanism of action of the intervention and the possible adverse effects. The authors use Pentaherbs Formula to educate to readers on efforts in Traditional Chinese Medicine research to adopt this historic and unique complementary medicine as a safer and scientific-based therapy for atopic dermatitis. In closing, Atopic Dermatitis: From Diagnosis to Treatment focuses on topical corticosteroids that are commonly used by dermatologists and general physicians to treat selected difficult dermatoses effectively.

Get a quick, expert overview of the use of current and novel immunotherapies for use in the management and treatment of allergic reactions and diseases. This concise resource by Dr. Linda Cox covers the full range of allergic disease, including aeroallergens, asthma, food allergies, atopic dermatitis, and stinging insects. With essential coverage of allergen immunotherapies in addition to key topics on emerging allergen-associated immunomodulators, this succinct, comprehensive reference consolidates today's available information on this timely topic into a single convenient resource. - Discusses timely topics such as food tolerance, allergy, and allergen unresponsiveness; biologics for COPD and pediatric asthma; and adherence and pharmacoeconomics. - Summarizes practical guidelines and recommendations for use of immunotherapies in clinical practice. - Provides insight into the background and history of immunotherapies as a treatment for allergic disease. - Includes developments on the horizon, including alternative immunotherapy routes and modified allergens.

Patient adherence to a given treatment plan directly correlates to the quality of disease outcome. In looking at the how and why behind patient adherence and non-adherence to a treatment regimen, understanding realistic expectations of a patient can provide a beneficial guide towards providing optimal healthcare.Treatment Adherence in Dermatology offers insight and strategies for understanding and promoting treatment adherence with a focus on dermatological conditions, specifically psoriasis, atopic dermatitis, and acne. Reasons for non-adherence are investigated particularly in populations such as children and patients with multiple co-morbidities. The proposed text provides patient and physician-centered strategies alongside technological advancements to promote adherence. Written for the practicing dermatologist, this title will find audience with primary care physicians, students, residents, and other practicing doctors alike.

Der Arzneiverordnungs-Report ist seit 1985 eine gemeinsame Publikation von Autoren aus Pharmakologie, Klinik, Praxis, Gesundheitsökonomie und Krankenversicherung. Basis sind die Verordnungsdaten von Arzneimitteln für ambulante Patienten der gesetzlichen Krankenversicherung (GKV). Datenbasis des Jahres 2019 sind 820 Millionen Verordnungen von 179.805 Vertragsärzten und 63.360 Vertragszahnärzten für 73,195 Mio. GKV-Versicherte.Die allgemeine Verordnungs- und Marktentwicklung wird in 5 Kapiteln dargestellt, in denen zusätzlich 31 neue Arzneimittel des Jahres 2019, Biologika und Biosimilars, 10 Jahre AMNOG und europäische Arzneimittelpreise für Biosimilars thematisiert werden. Die speziellen Verordnungsdaten der 3000 meistverordneten Arzneimittel werden in 39 Kapiteln für die führenden Indikationsgruppen evidenzbasiert analysiert.

This book comprehensively and thoroughly reviews the current literature regarding the impact of health disparities and socioeconomic factors on allergic diseases outcomes: such as food allergies and anaphylaxis. The morbidity associated with these conditions is significantly higher in under-privileged populations around the world, including groups who have experienced greater social or economic obstacles to health based on racial, socioeconomic, gender, geographic location. Health Disparities in Allergic Diseases presents evidence and reviews studies from both developed and developing countries that witness health disparities in allergic disease.Concise in format, Health Disparities in Allergic Diseases: An Evidence-Based Look at Causes, Conditions, and Outcomes is made up of 11 expertly written chapters and divided into two parts. It begins with an introductory on global health through an analysis of the theoretical framework of epidemiologic transition. Subsequent chapters then review the socioeconomic and racial variables in treating allergic diseases using a multifactorial approach. Part II discusses disparities in allergic conditions, including asthma health, rhinitis and rhinosinusitis, food allergy, and atopic dermatitis. The book concludes with an exploration of potential strategies to providing solutions for asthmatic impoverished populations.Health Disparities in Allergic Diseases is a practical resource that can be used by researchers and clinicians in the field of allergy who are interested in learning about health related disparities in the context of allergic conditions or who seek solutions for this important issue.

Das Buch beschreibt anschaulich die häufigsten Hauterkrankungen die in der Allgemeinpraxis begutachtet und behandelt werden müssen.Wie viele Patienten mit Hautkrankheiten kommen täglich in Ihre Arztpraxis? Und wie oft präsentieren Patienten in der Sprechstunde zusätzlich zu anderen Beschwerden „nebenbei“ noch ein Hautproblem?Sicher ist: Dermatologische Probleme gehören zu den häufigsten Vorstellungsgründen in der Allgemeinmedizin. Ob Akne, Neurodermitis, Schuppenflechte, Skabies, Warzen oder lästige Hautprobleme wie Aphthen, Hyperhidrosis, Perléche, Sonnenallergie oder brüchige Fingernägel – erkennen, differenzieren und behandeln Sie kompetent die häufigsten Hautkrankheiten!Prägnante Texte zur Entstehung, den diagnostischen Erkennungs- und Unterscheidungsmerkmalen und der aktuellen optimierten Therapie unter Nennung der sich in der Praxis bewährten Wirkstoffe und Präparate informieren Sie zusammen mit zahlreichen Farbfotos über allesWichtige zu den einzelnen Hautkrankheiten. Ihre Patienten werden Ihnen außerdem für zahlreiche Pflegetipps dankbar sein, damit die Haut nach einer erfolgreichen Heilung nicht wieder erkrankt.Diese schnelle und übersichtliche Informationsquelle zu den häufigen dermatologischen Problemen werden Sie regelmäßig in Ihrer Sprechstunde zur Hand nehmen!

Advances in Health and Disease. Volume 19 begins by exploring differential diagnosis, a compilation of diagnostic possibilities, typically through the medium of evaluation of the prior probability of a specific diagnosis, given a particular test result (so-called Bayesian analysis). The authors discuss corticosteroids which have become indispensable in the treatment of a number of dermatological conditions. The advancement of newer steroid molecules with their vast anti-inflammatory, anti-mitotic, immunosuppressive and vasoconstrictive actions has completely changed dermatology. This compilation also addresses angiogenesis or neovascularization,the physiological process involving the sprouting of new blood vessels from pre-existing ones. These processes are vital for tissue development and wound healing in damaged tissues. Bovine mastitis in India in India is studied, particularly the diagnostic techniques used for the rapid detection of microorganisms from bovine mastitic milk. This collection covers some issues related to the acetabulum, such as the treatment of acetabular fractures which affect the anterior column, the modified Stoppa technique in acetabular fractures, and the surgical treatment of displaced acetabular fractures with a pararectus approach. In addition, some issues related to the shoulder are discussed, such as the evaluation of rotator cuff tears, approaches for shoulder instability, subacromial impingement syndrome, superior labrum anterior posterior lesions, and frozen shoulder. Diaphyseal clavicle fractures, distal clavicle fractures and acromioclavicular joint dislocation, scapular neck and body fractures, glenoid fractures, and other relevant issues are also discussed. The penultimate chapter focuses on matters pertaining to the humerus, such as: the non-operative treatment of proximal humerus fractures, internal fixation in proximal humerus fractures, hemiarthroplasty in proximal humerus fractures, and reverse total shoulder arthroplasty in proximal humerus fractures. In closing, using a phenomenological design, the researchers explore the experience of suffering as voiced by male and female patients six to twelve months after hospitalization for blunt trauma.

Conditions of the hair and scalp often cause significant psychological distress and sometimes physical discomfort for patients. Similarly, finding the right treatment can prove challenging for the physician. Hair and Scalp Treatments -- A Practical Guide, focuses on therapy with each chapter briefly describing the disease to the reader and then teaching the step-by-step therapeutic algorithm. Procedures commonly used in the treatment of alopecias are also reviewed and detailed in specific chapters.This book also discusses everyday questions that patients commonly ask doctors and provides practical tips such as how to recommend the best shampoo, conditioner or hair dye for your patient, or how to prescribe the right nutritional supplements. There are additional sections on future treatments on the horizon and how regenerative medicine can be used.Hair and Scalp Treatments -- A Practical Guide, is the only book of its kind focused on treatment and addresses topics that are not covered by current titles on hair disorders. Written and edited by leading experts in the field, this practical guide can be used not only by dermatologists but by general practice and family physicians as well.

This concise text presents the essential points of diagnosis and a quick guide to what are currently the best evidence-based practices in treatment methods. In addition to material on the diseases themselves, there are useful appendices on how to carry out ancillary procedures.Contents: Acute paronychia • Bowen disease • Brittle nails • Chronic paronychia • Eczema • Erythronychia • Glomus tumor • Hematomas • Herpes simplex • Ingrowing nail • Lichen planus • Melanoma • Melanonychias • Myxoid cysts • Onycholysis • Onychomatricoma • Onychomycosis • Onychotillomania • Psoriasis • Retronychia • Squamous cell carcinoma • Subungual exostosis • Trachyonychia • Transverse overcurvature • Warts • Yellow nail syndrome • Practical procedures • Preparing a biopsy specimen

This concise, comprehensive book provides the most recent updates on rosacea management strategy, pathophysiology, genetic and environmental contribution, comorbidities, and other various topics. It meets the market need for a book that examines topics that are not typically included in rosacea textbooks. Beginning with a discussion on the current clinical understanding of the disease, this book reviews the aforementioned topics in a thorough yet accessible fashion. Complete with tables detailing a variety of drugs in an unbiased manner as well as color photos of real patients, each chapter aims to relay useful, practical information to dermatologists at every stage in their career. A valuable contribution to the Updates in Clinical Dermatology Series, Rosacea aims to promote the rapid and efficient transfer of medical research into clinical practice for the benefit practitioners and patients alike.

This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma ‘difficult to treat'. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate “difficult” from “severe refractory” asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes ‘state of the art'reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The updated visual atlas of family medicine—enhanced by more than 2,000 illustrations A Doody's Core Title for 2020!'The Color Atlas and Synopsis of Family Medicine, Third Edition, will be an invaluable addition to busy physicians'clinical libraries. Its wide-ranging topics covering the gamut of family medicine are thoroughly covered and efficiently organized for point-of-care use. This, as well as its useful and exceptional photographs, will make it a resource the clinician will reach for again and again during evaluation of unfamiliar conditions. Residents and students will find it particularly useful as they systematically broaden their experiences and fund of knowledge—well done!'—Family Medicine A Doody's Core Title for 2019! The Color Atlas and Synopsis of Family Medicine simplifies and supports visual diagnosis like no other guide. The text is bolstered by more than 2,000 illustrations, consisting of state-of-the-art photos and drawings, most in full color. Page after page, the book's precise clinical images are integrated with evidence-based diagnostic pearls presented in bulleted text—ideal for time-pressed physicians. Sections highlight specific diseases and disorders, organized by anatomic and physiologic systems, with each chapter opening with a patient story to connect the photographs with real-life clinical scenarios. Every condition features a consistent format that includes the patient story, Epidemiology, Etiology and Pathophysiology, Diagnosis, Differential Diagnosis, and Management to aid the reader in navigating to the right section with ease and efficiency. NEW TO THIS EDITION: New chapters on Mental Health, the Opioid Crisis, Dementia, Sports-related Head Injury, and LGBT health issues New chapter on Zika, Ebola and other emerging infections expand the insights in the Global Health chapter New Foundations of Dermatology section contains a dermoscopy chapter, plus chapters on dermatology terminology, topical and intralesional steroids, and biopsy principles and techniques Management section is now divided into first- and second-line therapies

The revised fourth edition of Evidence-Based Gastroenterology and Hepatology continues to provide the most current, evidence-based information for determining the appropriate medical and surgical options for screening for, diagnosing, and treating gastrointestinal conditions. With contributions from an international team of leading experts in the field, the 4th edition includes practical recommendations for the care of individual patients based on the latest scientific evidence.