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Summary: This book collects recent research in the field of care for neurodevelopmental disorders, emphasizing transdisciplinary work in clinical, educational and family contexts. It presents an opportunity to learn about the impact of participation on children and adolescents with neurodevelopmental disorders. Mainly, new therapeutic approaches are presented in children and adolescents with autism spectrum disorder, attention-deficit/hyperactivity disorder, or motor coordination disorders.

Brain, Decision Making, and Mental Health acknowledges that thinking is not a constant phenomenon but varies considerably across cultures. Critical thinking is particularly important in bridging thinking divisions and its applicability across sciences, particularly medical sciences. We see critical thinking as educable and the arts as means to achieve this purpose. We address the multidimensional relationship between thinking and health and related mechanisms. Thinking mainly affects emotion regulation and executive function; in other words, both mental and physical health are related as a function of thoughts. Considering the thinking‐feeling‐emotion regulation/executive function pathway, it would be reasonable to propose thinking capacities‐based interventions to impact emotion regulation and executive function, such as mindfulness and psychotherapy. We review decision-making taking place in integrated and social contexts and discuss the decision-making styles-decision outcomes relation. Finally, artificial thinking and intelligence prepare us for decision-making outside the human mind.

The fourth edition of this concise and accessible book continues to provide readers with the fundamentals of clinical neuroscience, the essentials of neurological functioning, and the neurological basis for a range of rehabilitation practices.The book starts by illustrating the basics of neuroanatomy, before addressing the function of neurological systems underlying motor, sensory, visual, perceptual, cognitive, emotional, and memory disorders. Along with new full color illustrations and photographs, the book has been updated to include the following additional material: Full screening procedures have been added to the cranial nerve section. Full color illustrations have been added to the special sense receptor section to illustrate the clinical pathology underlying visual field impairments. New sections have been added addressing attention and cognition. A subsection,'Occupational Performance Implications,'was added to all sections to help readers understand how function/dysfunction of neuroanatomical systems impact performance in daily life activities. This updated fourth edition continues to be essential reading for any healthcare professional working in rehabilitation, or students on the journey to become rehabilitation professionals.

This book presents comprehensive coverage of the RASopathies, one of the largest known recognizable patterns of malformation syndromes, affecting approximately 1 in 1,000 people. These syndromes include neurofibromatosis type 1, Noonan syndrome, Noonan syndrome with multiple lentigines, Costello syndrome, cardio-facio-cutaneous syndrome, Legius syndrome, capillary malformation-arteriovenous malformation syndrome, SYNGAP1 syndrome and central conducting lymphatic anomalies. Noted physician and authority Katherine Rauen and an assembly of the top international experts present detailed discussions of both the science and clinical implications of these fascinating disorders. The major topics covered in this book include the syndromes and genes, the RAS pathway, phenotypic features, animal modeling and treatments. The book will appeal to a wide audience, including clinicians and basic scientists alike such as medical geneticists, genetics counsellors, oncologists, neurologists, cardiologists, dermatologists, behavioralists, orthopedists, ophthalmologists, neuroscientists, RAS biologists, and signal transductionists. This book is also intended for advocate leaders, trainees, and families with RASopathies.

This book focuses on the clinical and preclinical research on traumatic brain injuries where age at time of injury (young versus aged) reveals both parallel and divergent findings at the molecular, cellular, and behavioral levels with insights into alterations in brain structure and function and the implications for recovery. The authors address the hurdles that have been overcome, consider new directions inspired by the most recent research, and the value of data sharing and evidenced based-practice. Traumatic Brain Injuries: Tackling the Unique Terrain of the Injured Young and Aged Brain explores the challenges imposed by an injury that not only causes tissue damage but disrupts brain development and may incite pathological events in the aging brain. With the proliferation of the research literature in traumatic brain injuries, this is the time for a book that surveys the landscape and assesses where the field is headed and what is needed moving forward.

The book delves into the multifaceted world of migraine pain, offering a profound understanding of its underlying pathophysiology and presenting established treatment strategies for its effective management. It discusses the intricate world of migraine pain, offering valuable insights into its diverse aspects. Starting with an exploration of migraine's epidemiology and etiology and the complex factors contributing to this debilitating headache disorder. This book explores the significance of lifestyle changes and offers practical strategies for incorporation. Furthermore, the impact of diet and nutrients on migraine management is extensively covered, shedding light on their role in alleviating symptoms. This book serves as a comprehensive guide, blending scientific insights with practical approaches, making it an indispensable resource for healthcare professionals, researchers, and individuals seeking a deeper understanding of migraine pain. By addressing both established practices and cutting-edge advancements, it bridges the gap between knowledge and effective management, offering a holistic perspective on this challenging condition.

This book reviews all aspects of major depressive disorder (MDD), casting light on its neurobiological underpinnings and describing the most recent advances in management. The book is divided into four sections, the first of which discusses MDD from a network science perspective, highlighting the alterations in functional and structural connectivity and presenting insights achieved through resting state functional MRI and the development of neuroimaging-based biomarkers. The second section examines important diagnostic and neurobiological issues, while the third considers the currently available specific treatments for MDD, including biofeedback, neurofeedback, cognitive behavioral therapy, acceptance and commitment therapy, neuromodulation therapy, psychodynamic therapy, and complementary and alternative medicine. A concluding section is devoted to promising emerging treatments, from novel psychopharmacological therapies through to virtual reality treatment, immunotherapy, biomarker-guided tailored therapy, and more. Written by leading experts from across the world, the book will be an excellent source of information for both researchers and practitioners.

In recent years, gold-standard experimental evidence on the benefits of reading fiction has exploded. Why do we love stories from books, TV and movies, and videogames? What do fictional stories have to do with stories from real life? How do stories impact our own and our children's brain development, reading skills, social understanding, and well-being? In How Stories Change Us, Elaine Reese integrates the latest scientific research on stories from fiction (books, TV shows and movies, videogames) with stories from real life (our personal experiences, including on social media) across the lifespan. The book offers an authoritative yet accessible overview of the new interdisciplinary science of stories, told by a developmental psychologist and autobiographical memory expert with over thirty years of experience conducting research on stories. Throughout, Reese adopts a developmental perspective by tracing the impact of stories from pre-birth to old age. Drawing upon illustrative examples from her 20-year longitudinal study Origins of Memory as well as from her own life, Reese synthesizes cutting-edge research on the benefits and pitfalls of stories and offers practical tips for parents, teachers, librarians, and policymakers. Reese concludes that people have a preferred fictional story delivery system, whether it's reading, watching, or gaming, and she advocates for a more integrated science of stories to allow us to better choose the stories we consume and tell.

This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date. Converging evidence suggests that memories are stored, at least in part, as specific populations of engram cells. In this book, the leading experts in engram biology share their continuously refined insights on how engram cells contribute to information encoding and storage, across diverse brain regions and behavioral modalities. “Engrams: A Window into the Memory Trace'is broad in scope and spans molecular, cellular, circuit, computational as well as societal-philosophical aspects of memory engrams. Particular emphasis is placed on their emerging translational value for memory dysfunctions in age and stress-related disorders.

This important new book presents an introduction to Environmental Neuroscience, an emerging field devoted to the study of brain-mediated bidirectional relationships between organisms and their physical environments. Environmental Neuroscience offers a novel perspective in the human neurosciences, which have typically focused on the individual isolated from its natural habitat. The book presents the theoretical background of the field, discusses how the environment impacts humans and how humans impact the environment, explores the neuroscience of the built environment, and addresses special populations and presents different methodological approaches. Environmental Neuroscience bringing together the top authorities in the field, will appeal to neuroscientists and to a range of scholars from public health, urban studies, human geography, and architecture who are searching for guidance on what characterizes a health-promoting environment.

The book delves into the fascinating intersection of neuroscience and negotiation, offering a groundbreaking exploration into how our brains influence and are influenced by the negotiation process. With an emphasis on practical application, this book is designed to equip readers with a deep understanding of the neurological mechanisms during negotiations, empowering them to optimize their approach and achieve better outcomes in business deals. Structured for both accessibility and depth, the book begins with an exploration of the fundamental principles of negotiation neuroscience, providing readers with a solid foundation of knowledge. It then progresses to more advanced topics, such as the role of emotions, cognitive biases, and decision-making processes in negotiations. Each chapter is rich with real-world examples, case studies, and practical tips, ensuring readers can immediately apply their newfound insights to their negotiation scenarios. In today's rapidly evolving business landscape, where successful negotiation skills are essential for navigating complex deals and relationships, understanding the neuroscience behind negotiation is more crucial than ever.

This book intends to present a series of insights coming from in-depth investigation of brain and mathematical cognition in Chinese population. Specifically, the book introduces research on the associations among number sense, visual form perception and mathematical fluency; symbolic and non-symbolic mental number line; and the role of spatial modeling and logical inference in mathematical problem solving. The book summarizes author's previous studies on the involvement of semantic network other than visuospatial network in mathematical cognition. The three-component mathematical model that comes out of more than 10 years of research on mathematical cognition is introduced. The book presents the effect of learning experience on arithmetic-related brain system. Chinese abacus that can be used to eradicate developmental dyscalculia in classroom is briefly discussed. Special attention in this book is paid to mathematical anxiety and mathematical learning disorders in Chinese schoolchildren. Finally, gender differences in mathematical cognition are also reviewed.

The book explores the intricate relationship between nutrition, brain function, and psychiatric disorders. The first section of the book delves into the neurobiological aspects of psychiatric disorders, including the neuroanatomy, neuropathology, biochemical and neuropharmacology factors that play a role in the development of these disorders. It also discusses the impact of human nutrition on brain function and the implications of nutrition and metabolism on psychological functioning. The next section focuses on the diet-brain connection, exploring nutritional psychiatry and the current state of evidence, the role of the microbiome, and the effects of certain foods such as chocolate and coffee on mood and mood disorders. The chapters also examine the impact of diet on mental health and cognition across the lifespan and provides a case study of the relationship between diet and psychological health. In the final section, the book delves into the nutritional treatment of psychiatric disorders, including the psychopharmacology of psychiatric disorders and food intake, and multidisciplinary approaches to psychiatric treatment.. Overall, this book offers a comprehensive and evidence-based examination of the complex relationship between nutrition, brain function, and psychiatric disorders, and provides a foundation for further research and development of effective nutritional interventions for the treatment of these disorders.

The Ecological Brain is the first book of its kind, using complexity science to integrate the seemingly disparate fields of ecological psychology and neuroscience. The book develops a unique framework for unifying investigations and explanations of mind that span brain, body, and environment: the NeuroEcological Nexus Theory (NExT).Beginning with an introduction to the history of the fields, the author provides an assessment of why ecological psychology and neuroscience are commonly viewed as irreconcilable methods for investigating and explaining cognition, intelligent behavior, and the systems that realize them. The book then progresses to its central aim: presenting a unified investigative and explanatory framework offering concepts, methods, and theories applicable across neural and ecological scales of investigation. By combining the core principles of ecological psychology, neural population dynamics, and synergetics under a unified complexity science approach, NExT offers a compressive investigative framework to explain and understand neural, bodily, and environmental contributions to perception-action and other forms of intelligent behavior and thought.The book progresses the conversation around the role of brains in ecological psychology, as well as bodies and environments in neuroscience. It is essential reading for all students of ecological psychology, perception, cognitive sciences, and neuroscience, as well as anyone interested in the history and philosophy of the brain/mind sciences and their state-of-the-art methods and theories.

This book addresses the growing need for machine learning and data mining in neuroscience. The book offers a basic overview of the neuroscience, machine learning and the required math and programming necessary to develop reliable working models. The material is presented in a easy to follow user-friendly manner and is replete with fully working machine learning code. Machine Learning for Neuroscience: A Systematic Approach, tackles the needs of neuroscience researchers and practitioners that have very little training relevant to machine learning. The first section of the book provides an overview of necessary topics in order to delve into machine learning, including basic linear algebra and Python programming. The second section provides an overview of neuroscience and is directed to the computer science oriented readers. The section covers neuroanatomy and physiology, cellular neuroscience, neurological disorders and computational neuroscience. The third section of the book then delves into how to apply machine learning and data mining to neuroscience and provides coverage of artificial neural networks (ANN), clustering, and anomaly detection. The book contains fully working code examples with downloadable working code. It also contains lab assignments and quizzes, making it appropriate for use as a textbook. The primary audience is neuroscience researchers who need to delve into machine learning, programmers assigned neuroscience related machine learning projects and students studying methods in computational neuroscience.

This volume explores indirect parenting behavior that changes the structure of the parent-child relationship, examining the ecological dimension of parenting in addition to nurturance and control.Drawing on neuroscientific research in parenting, it provides a model for how children learn implicitly and how parents can relate to children through indirect means. Roberts argues that first-order parenting techniques, teaching specific behaviors to reduce unwanted child behaviors, are overused. He examines and offers guidance on how indirect interventions that place emphasis on the interactional components of the parent/child relationship, such as modelling, storytelling, reframing, humor, and paradox, can support parents and children in developing positive relationships. • Addresses the latest brain research and its application to parent/child interactions• Introduces the student to aspects of the parent/child relationship that are not covered in most courses• Useful to clinicians who work directly with parents • Offers a perspective on parenting that differs from most parenting models• Facilitates awareness of how unconscious and nonverbal communication affects parenting• Serves to deepen the relationship with the child and curb unwanted behaviorIndirect Parenting Interventions, Neuroscience and the Parent-Child Relationship will be thought-provoking reading for students and scholars of parenting and family systems, as well as clinicians who work directly with parents giving them a broader perspective in dealing with parent/child interactions.

Explore the latest developments in biological psychology today with the most widely used text for this area of study: Dr. James Kalat's BIOLOGICAL PSYCHOLOGY, 14E. This edition uses a clear writing style, precise examples and the latest research to make biological psychology understandable and to emphasize its importance to psychology as well as biology and pre-med study. Thought-provoking content, insights from contemporary researchers, amusing anecdotes and even try-it-yourself activities help convey the excitement behind biological explanations of behavior. This edition introduces breakthrough findings with more than 500 new research references as recent as 2022. You explore new insights into brain functions, autism, antidepressants and mental enhancement and weight-loss drugs as well as the latest on auditory changes, pain mechanisms and the olfactory effects of COVID-19. Cengage Infuse digital resources are also available with interactive learning tools.

This Springer Major Reference Work provides a detailed translational overview of neuroimmune diseases for neuroscientists and clinicians, clarifying the pathological mechanisms underlying neuroimmune diseases and building a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The new edition features updated chapters throughout, including coverage of new findings, new diagnostic criteria, and therapeutic algorithms. Neuroimmune Diseases, 2nd edition, also includes new chapters with a translational approach. The book will be invaluable for use in clinical practice of neuroimmune diseases.

This book brings together the exciting new findings that will bring us closer to a better understanding of the alterations of neuronal connectivity in autistic brains. This volume authoritatively covers the epidemiology, physiology, neurodevelopment, genetics, environmental influences, imaging studies, neuroanatomy, and neurochemistry of autism spectrum disorders. While the neurobiology of autism is still a long way from being understood, this book posits techniques, such as using brain imaging to find signatures in early days of life, that could help move the diagnosis and help identify neural pathways. Understanding these mechanisms opens the possibility to pharmacological, behavioral, and psychosocial therapeutic interventions. With contributions from the leading international autism researchers, Neurobiology of Autism Spectrum Disorders is the go-to reference for researchers and clinicians with an interest in understanding the underlying neurobiologyof autism spectrum disorders.

This book reviews neurophysiological biomarkers in neuropsychiatric disorders from the viewpoint of the 21st Century Cures Act, which encourages the use of biomarkers for a variety of purposes during drug development. It covers both traditional etiologic uses of biomarkers and the more recent Biomarkers, EndpointS, and other Tools (BEST) classification scheme used by the FDA, which permits biomarkers for purposes of susceptibility, diagnosis, monitoring, prognosis, pharmacodynamics/response, and safety. The first section of the book describes potential uses of neurophysiologic biomarkers. Subsequent sections focus on a wide range of conditions, including schizophrenia, autism spectrum disorder, Parkinson's disease, and depression, as well as cross-diagnostic and translational uses, including monkey and rodent analogs. The purpose of the book is to help clinicians understand how neurophysiological biomarkers may be used to understand and manage clinical conditions; to help researchers to understand how biomarkers may be used translationally to test specific theories; and to help pharma investigators to understand how biomarkers can be used to accelerate treatment development.

This edited volume describes key domains of the emerging research literature linking exercise and mental health. The volume is divided into three sections. The first section provides an overview of foundational knowledge regarding basic processes of exercise, including neurocircuitry, neurotransmitter, and immunology systems. The second section describes emerging research on the acute impact of exercise on affect, mood, and cognition. The third section explores the role of exercise in the etiology and treatment of related mental and physical health disorders, including depression, PTSD, eating disorders, and autoimmune disorders. Collectively, this volume provides readers with foundational knowledge of what exercise is, the basic brain, behavioral and cognitive processes engaged by exercise, and a role of exercise in developing and treating mental health disorders.

The Neuroradiology Board's Favorites is a case-based review book focused on the imaging of pathology-proven lesions related to the central nervous system.The mission of this book is to help readers revise the core concepts and maintain knowledge of neuroradiology from radiology, neurology, and neurosurgical perspectives. This study companion features a unique design and is structured in two sections, totalling 15 chapters. It includes 100 clinical scenarios and imaging, supplemented by more than 170 multiple-choice questions in a convenient format suitable for self-study. The questions are attached to each case scenario in a style that mirrors the format adopted by the majority of local, regional, and international board examinations. The answers and explanations appear immediately below the questions to enhance readability. The content of this book is an adjunct to existing texts and does not intend to be the primary source of information; it aims to help readers identify their relevant strengths and weaknesses in the area and is based on the most up-to-date best practice evidence. This book is targeted at students of radiology, neurology, neurosurgery, and neurosciences. In addition, it can be beneficial for residents, fellows, and young attendings to prepare for exams or practice.

In the face of recent viral outbreaks and a global viral pandemic, the necessity for innovation and continued rapid advancement in viral diagnosis and treatment methods has become even more apparent. Global Virology IV: Viral Disease Diagnosis and Treatment Delivery in the 21st Century explores the latest advances in virology and trends in clinical practice, focused on foundational principles and advancements expected to significantly impact this field. Chapters address SARS-CoV-2, Ebola, Zika, Mpox, and Hepatitis C, among other key viral threats, before presenting a detailed analysis of antiviral agents broadly and concerning specific vulnerable populations such as stem cell and solid organ transplant recipients. It is designed as a helpful resource for medical students, scientists, and professionals, bridging current practice and future applications and inspiring further innovations and improvements in global health.

Brain science in the form of neuroscientific evidence now appears frequently in courtrooms and policy discussions alike. Many legal issues are at stake, such as how to separate the best uses of brain science information from those that are potentially biasing or misleading. It is crucial to evaluate brain science evidence in light of relevant legal standards (such as the Daubert and Frye Rules). Brain Science for Lawyers, Judges, and Policymakers responds to this rapidly changing legal landscape, providing a user-friendly introduction to the fundamentals of neuroscience for lawyers, advocates, judges, legal academics, and policymakers. It features detailed but clear illustrations, as well as a comprehensive and accessible overview of developments in legally relevant neuroscience. Readers will learn brain science terms, how to understand and discuss brain structure and function in legally relevant contexts, and how to avoid over- or under-interpreting neuroscientific evidence. The book begins with a survey of the kinds of litigation, legislation, and regulation where neuroscience is currently being used. It provides accessible descriptions of basic brain anatomy and brain function as well as an overview of how modern technologies can reveal the brain structures and brain functions of individuals. It finishes with cautions and limitations, including timely and thought-provoking observations about where the future of neurolaw might lead. Throughout, the authors offer clear and concise guidance on understanding both the promise and the limitations of using brain science in law and policymaking.

Principles and Advances in Population Neuroscience is aimed at enhancing our understanding of forces that shape the human brain and, as such, contribute to inter-individual variations in cognitive abilities, behavior and mental health throughout the lifespan. This book builds on a monograph'Population Neuroscience'(published by Springer in 2013; ISBN: 978-3-642-36450-1), a recent book on “Digital Ethology: Human Behavior in Geospatial Context” (published by MIT Press in 2024; ISBN: 9780262548137), and the collaborative work carried in the CHARGE and ENIGMA Consortia. Using collective expertise and knowledge with combining epidemiology, genetics and neuroimaging, the authors provide an overview of the basic principles and current advances in this field.

This book offers an overview of the history, definitions, and treatments for autism spectrum disorders from 1943 to the present day. Bridging the gap between psychology and neuroscience through a rigorous reconstruction of eighty years of research, the author retraces the emergence of the definition of autism and the description of its characteristics, the history of the diagnosis and standardized classification of ASD in the Diagnostic and Statistical Manual of Mental Disorders, and the development of etiological research and therapeutic interventions in medical, psychoeducational, and alternative therapies. The content spans neurology, genetics, psychiatry, and medicine, integrating discoveries from different fields to shed light on relevant factors of the pathology and dynamics of ASD. A useful resource for students and researchers in psychology, psychiatry, special education, and healthcare, this book unveils the latest advances in the field of ASD and discusses the research agenda for the years to come, showcasing multidirectional approaches to improve the quality of life of autistic people.

This new reference provides a comprehensive overview of intellectual and developmental disabilities, incorporating multiple perspectives and disciplines (including developmental neuroscience, genetics, psychiatry, and psychology) with a multifaceted approach, offering readers appreciation for the richness of the population and field. It provides readers with an understanding of the developmental, biological, and behavioral aspects of developmental disabilities with the aim of understanding their causes, the differences between disabilities, and familiarity with the prognosis and developmental outcomes for children diagnosed with various developmental disabilities.

This book presents the proceedings of the NeuroIS Retreat 2023, May 30–June 1, Vienna, Austria, reporting on topics at the intersection of information systems (IS) research, neurophysiology and the brain sciences. Readers will discover the latest findings from top scholars in the field of NeuroIS, which offer detailed insights on the neurobiology underlying IS behavior, essential methods and tools and their applications for IS, as well as the application of neuroscience and neurophysiological theories to advance IS theory.

This book focuses on the latest research on the genetic basis of the regulation of sleep and wakefulness and of sleep and circadian rhythm disorders, which has been expanding rapidly due to advances in genetics. The book reviews the latest genetic discoveries in animals and humans and explores their implications for getting a good night's sleep. Philp Gehrman, Alex Keene, Struan Grant, and a cadre of top sleep researchers and clinicians explore the genetics of sleep and sleep disorders in depth. The book should appeal to sleep medicine specialists, psychiatrists, geneticists, and neuroscientists.

How to Build a Human Brain takes a developmental approach to understanding brain structure and function. It guides readers through the evolution of the human brain, from its cellular building blocks, up to hind brain structures and functions, and through to neocortex and associated functions. In doing so, it enables students to develop a comprehensive knowledge of the relationship between brain networks and functions, neural underpinnings of functional problems seen after neuropathology, and neuroanatomy.Written in an engaging style, each chapter follows a blueprint format with subsections on issues like'damage and repair'and'faulty wiring'as the brain is ‘built'across the course of the book. The author includes illustrative case studies and entertaining fast fact boxes to highlight the real-word relevance of each brain structure being examined. This textbook offers an accessible reference for students of neuroscience, cognitive neuroscience, neuropsychology,and biological psychology.

This book brings together neuroscience and psychoanalysis to explain the complex interactions between neurobiological and psychological phenomena involved in the development of human attachment and affect regulation. The author reviews research from the burgeoning fields of affective neuroscience and neuropsychoanalysis to tell the story of how the discovery of a specific hormone – oxytocin – paved the way for the study of the neurobiological bases of emotions in a way that can contribute to integrate neuroscientific research into psychotherapy, especially for the treatment of anxiety disorders. The book starts by presenting a brief history of neuroscience, spanning from the discovery of oxytocin, at the beginning of the 20th century, until the emergence of affective neuroscience and neuropsychoanalysis as new scientific fields at the turn of the 20th to the 21st century. Then it reviews the long tradition of psychoanalytic research on human attachment starting with John Bowlby's seminal Attachment Theory and explains how these early findings have been complemented by neuroscientific and psychological research on brain development and affect regulation. Finally, the two last chapters of the book show how this prolific dialogue between neuroscience and psychoanalysis can contribute to the future of psychotherapy. Oxytocin, Well-Being and Affect Regulation was originally published in Portuguese for the Brazilian market and this English edition for the international market is a revised version with two new additional chapters. It will be of interest to both students and professionals from different fields within the behavioral and health sciences, such as psychology and medicine, who will find in this book a brief and accessible introduction to key topics in the emerging fields of affective neuroscience and neuropsychoanalysis. The translation of the original manuscript in Portuguese into English was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.

Adaptations to maternal physiology are required for a successful pregnancy outcome. These changes are primarily orchestrated by the mother's brain and involve multiple neuroendocrine systems. For this book, the editors have gathered internationally recognized experts who have contributed to the major advances in our understanding of different aspects of the neuroendocrine regulation of mammalian pregnancy and lactation. The book begins with a discussion of how pregnancy is recognized and maintained and the role of the placental hormones in supporting key adaptations required for a successful pregnancy. The next few chapters focus on the neuroendocrine adaptations that occur during pregnancy in some key regulatory processes to ensure a sufficient supply of energy and nutrients, protect the fetus from potentially harmful maternal stress hormones, and prepare mammals for birth, milk production, lactation and motherhood. Finally, our current understanding of how the significant peripartum hormonal changes contribute to the mother's cognitive function and mood is examined. This book provides a broad overview of the finely orchestrated neuroendocrine adaptations that occur in pregnancy and lactation and discusses how such changes contribute to maximizing the likelihood of a positive outcome for mother and infant. Importantly the evidence for involvement of neuroendocrine dysregulation in some pregnancy-related complications, such as preterm birth and perinatal mood disorders is also highlighted. In addition to addressing fundamental mechanisms in the regulation of mammalian pregnancy and lactation, the book includes the most recent advances in the field made possible by utilizing the latest innovative research technologies. Moreover, it provides opinions on optimal experimental approaches, relates findings from experimental animal models with those from humans, and outlines the direction and opportunities for future research in this arena. It is an essential resource for undergraduate students, postgraduate students, and early career researchers embarking upon their journey in the fields of neuroendocrinology, endocrinology, reproductive biology or behavioural neuroscience. It also provides a valuable synopsis for established neuroendocrine researchers and educators, especially those whose interest transcends the nexus between neuroendocrinology and reproductive biology. This is the 15th volume in the International Neuroendocrine Federation (INF) “Masterclass in Neuroendocrinology” series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

This book is built around ion channel research and, more specifically, ion channels as important therapeutic drug targets. Under the editorial leadership of Gary Stephens in academic research and Edward Stevens from industry, the aim is to bring these strands together to provide a cutting-edge translational reference on ion channel drug discovery. Exploiting our knowledge of ion channel structure and function has clear current and future potential to intervene and correct the pathophysiology associated with debilitating conditions, including cardiovascular disease, diabetes, cystic fibrosis, pain, epilepsy, and neurodegenerative disorders. Individual chapters have a disease focus, also providing a “case study story” that will also appeal to a clinical audience, while background information on a given ion channel is presented to provide a solid reference for undergraduate and postgraduate teaching.

This unique, ground-breaking book is a comprehensive clinical guide to the psychiatric disorder of Delusional Infestation (DI). DI is a psychiatric illness characterized by patients holding a monothematic fixed belief of infestations on their skin, body, or immediate environment - a belief that is not supported by objective medical evidence. Delusional beliefs may be shared among individuals, and perceived pathogens include living organisms such as parasitic worms, bacteria, fungi, and insects. Organic or non-organic infiltration by fibres, threads, or other inanimate particles or objects, known or unknown to medical science, are also described by patients. DI is severely underreported because of social stigma, limited physician awareness, and patient doctor-hopping.Written for physicians, the book offers a multidisciplinary, compassionate care model for patients burdened by this pernicious disorder. Other health professionals and administrators will find the work highly valuable, as will professionals in fields such as veterinary medicine, pest management, entomology, parasitology, and information services supported by academia.The Physician's Guide to Delusional Infestation assembles and organizes all current knowledge of DI and presents material in three parts. Part I introduces and reviews DI's historical background, showing how our understanding of the condition has developed. Its concise sections include useful tables, illustrations, algorithms, and reference lists for clinicians who work with DI patients.Part II covers differential diagnosis, treatment, and ways to work effectively with DI patients. Since these patients are often high-functioning, particular techniques of interviewing, joining with patients, sampling, and laboratory testing are explained. International travel, physician fallibilities, possible alternative diagnoses, the Internet, and veterinary and public health concerns are all addressed.PartIII is a series of chapters written by experts in their fields. This section allows each author to present personal experiences from their respective professions -- observations and opinions that show a variety of perspectives among the book's authors. Part III includes a chapter on common human parasites with their biology, behaviours, and distributions. The book will serve as a comprehensive, yet concise, reference for physicians whose patients have unusual, baffling, or implausible medical histories and physical examinations. A soon to be gold-standard resource, The Physician's Guide to Delusional Infestation equips and empowers all physicians -- and many others interested in the topic -- with an expert, comprehensive understanding of this complex disorder.

The new edition of this popular book brings together experts in the field of Systems Neuroscience to present an overview of the area. Topics covered include how different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements; how nerve cells behave when connected together to form neural networks; the relationship between molecular and cellular approaches to understanding brain structure and function; the study of high-level mental functions; and studying brain pathologies and disease. Among the topics covered in the new edition are artificial intelligence-assisted computational neuroscience for deciphering neural networks, spatial transcriptomics single cell sequencing, and exome/whole genome sequencing for understanding brain disorders in human genetics. The best way to study the brain, the most complex organ in the body composed of 100 billion neurons with trillions of interconnections, is with a systems biology approach.

Vögel zeigen Mitgefühl, Spinnen offenbaren sich als Individuen, Fische erkennen sich im Spiegel; laufend entdecken Neurobiologen und Verhaltensforscher bei diesen Tieren neue Fähigkeiten. Nicht nur der Mensch und seine nächsten Verwandten – wie man lange Zeit dachte – sondern auch Vögel, Cephalopoden, Insekten, Spinnen und sogar Fische haben komplexe Gehirne entwickelt, die ungeahnte geistige Leistungen ermöglichen. Mehrfach hat die Evolution der Nervensysteme beeindruckende Höhen erreicht. Der Reichtum der tierlichen Innenwelten erregt Staunen und eröffnet neue Blickwinkel auf die philosophischen Facetten von „Bewusstsein“.Inspiriert und geführt durch Jakob von Uexküll und seine „Streifzüge“ nimmt dieses Buch seine Leser mit auf eine Bergwanderung durch die Evolution der Nervensysteme, von den einfachsten Nervennetzen der Quallen bis zu den kompakten Denkorganen der höchstentwickelten Tiere. Sie begegnen dabei einer genialen Spinne, einem paffenden Delphinbaby, einem imagebewussten Fisch und einem Oktopus mit Albträumen. Herrliche Tierfotographien von ausgewiesenen Artenkennern unterstützen das Staunen über die Schönheit und Raffinesse der tierlichen Subjekte, mit denen wir uns den Planeten teilen.

Explorations Between Psychoanalysis and Neuroscience brings together the life's work of David Olds, pioneering psychoanalyst, psychiatrist, philosopher, and key figure in neuropsychoanalysis.Throughout the chapters, the reader is taken on a journey through Olds'theories on psychoanalysis and neuroscience as he develops new ways of examining the brain and human thought. Olds instills in the reader the importance of taking an interdisciplinary approach to psychoanalysis, psychiatry and working with patients. He expands upon his philosophical background and integrates evolutionary biology, neurobiology, cognitive science and semiotics to show the importance of dual aspect monism in neuropsychoanalysis. The theories developed by Olds and presented in this volume will help analysts working with patients facing issues with memory, affect, consciousness, cognition and trauma, among other difficulties.This book will be essential reading to psychoanalysts and psychiatrists, as well as anybody interested in neuropsychoanalysis and the importance of an interdisciplinary approach to analytic thinking and practice.

The new edition of the highly popular, The Fractal Geometry of the Brain, reviews the most intriguing applications of fractal analysis in neuroscience with a focus on current and future potential, limits, advantages, and disadvantages. It brings an understanding of fractals to clinicians and researchers even if they do not have a mathematical background, and it serves as a valuable tool for teaching the translational applications of computational fractal-based models to both students and scholars. As a consequence of the novel research developed at Professor Di Ieva's laboratory and other centers around the world, the second edition will explore the use of computational fractal-based analysis in many clinical disciplines and different fields of research, including neurology and neurosurgery, neuroanatomy and psychology, magnetoencephalography (MEG), eye-tracking devices (for the fractal computational characterization of “scanpaths”),deep learning in image analysis, radiomics for the characterization of brain MRIs, characterization of neuropsychological and psychiatric diseases and traits, signal complexity analysis in time series, and functional MRI, amongst others.

This part of the book offers a multidimensional exploration of the neuroscience of yoga and in-depth insights into the neuroscientific underpinnings of yoga's impact on different disease conditions; explores the fascinating intersections between yoga, education, and neuroeconomics, as well as the relationship between yoga, spirituality, and consciousness; and acknowledges the importance of animal models in yoga research. In addition, the book addresses the concept of mind wandering and knowledge practice gap. This section provides valuable guidance for policymakers, healthcare professionals, and educators by exploring these aspects. Its comprehensive nature makes it an invaluable resource for researchers, practitioners, and individuals interested in unravelling the scientific complexities of the mind-body connection.

This book covers experimental theory and practice of yoga that have enhanced its neuroscientific understanding. This is an excellent handbook for the researchers in the field of evidence-based integrative health. It encompasses traditional and modern tools used in neuroscience. It also provides information for the modern biologists, physicians and policymakers, of how mind-body complexities in neuroscience, mental health and preventive healthcare can be useful for health and disease. It serves as a guide for integrative health practitioners, patients, educationists, philosophers, graduate students and faculty pursuing research in the field of biology, complimentary medicine, and other alternative therapies. The chapters in this book also serve as a comprehensive resource for clinical trials in Yoga. In addition, flow charts and illustrations have been provided to understand how healthy brain ageing can be achieved.

This book discusses the mechanism and therapeutic strategies of phytochemicals against brain ageing. It discusses the underlying anti-oxidative and anti-inflammatory mechanisms of the phytochemicals and the implications of these compounds in the prevention and treatment of geriatric diseases. It discusses the potential role of the highly complex interactive network between the gut and the brain in neurodegenerative diseases such as Parkinson's disease (PD), and Alzheimer's disease. The chapters provide insight into the mechanisms involved in brain ageing and the mechanism of actions of the phytochemicals that might be crucial in developing effective new therapies against brain ageing. The chapter also presents the mechanisms of action of phytoconstituents, bioavailabilities, and their effects on neuroinflammation. The chapters also examine the phytochemicals protection of neurons via targeting oxidative stress, mitochondrial dysfunction, neurotrophic factor deficit, apoptosis, and abnormal protein accumulation. This book aims to provide comprehensive and cutting-edge information on the potential neuroprotective role of phytochemicals on the brain and neurological disorders to researchers, neuroscientists, clinical nutritionists, and physicians.

This is an open access book. Homeostasis is upset by stress, which also triggers an adaptive reaction that shields an organism from harm. High allostatic load, on the other hand, might result from excessive stress or stress during a sensitive time, which eventually promotes or hastens maladaptive processes. Adverse childhood experiences, often known as ACEs, are early life stresses that individuals endure and are linked to the development of behavioural abnormalities and psychiatric problems in adulthood. Furthermore, there is evidence that people with early life stress have a more severe illness course and are less receptive to treatment for mood and anxiety disorders like depression.Stress throughout early childhood is linked to a modification of the brain's developmental trajectory, which can result in long-lasting behavioural alterations, but the consequences of stress in adulthood can be temporary and reversible. Behaviour problems brought on by ELS exposure can start in adulthood or during childhood or adolescence.A developing field of research, neuroscience, is expanding quickly. Neurology, psychiatry, and psychology are necessary for a deeper understanding of it. The purpose of this conference is to inform attendees of the most recent developments in the field of neuroscience education. The Faculty of Medicine at Universitas Sumatera Utara is hosting the 6th International Conference on Neuroscience, Neurology, and Psychiatry (ICoNaP) 2023 with the theme'The impact of early life stress on the neuroscience field'for psychiatrists, neurologists, general practitioners, and other interested specialists.Since 2018, ICoNAP has occurred annually. Speakers from many different nations are invited to the conference, both nationally and internationally. The committee has elected speakers from Malaysia, Singapore, Germany, Australia, India, Thailand, the United States, France, and Malaysia over theyears. This year's conference will be hosted virtually and will have speakers from Singapore, Malaysia, the United Kingdom, Japan, Australia, and Singapore.Researchers and specialists in the fields of neuroscience, neurology, and psychiatry can exchange ideas, experiences, and insights during the conference. Case studies and articles will have the opportunity to be published in international publications, and 920 researchers and professionals have so far taken part in previous ICoNAPs. More than 100 articles and case studies have also been released.

The second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases. The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases. Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases.

A thought-provoking examination of how insights from neuroscience challenge deeply held assumptions about morality and law. As emerging neuroscientific insights change our understanding of what it means to be human, the law must grapple with monumental questions, both metaphysical and practical. Recent advances pose significant philosophical challenges: how do neuroscientific revelations redefine our conception of morality, and how should the law adjust accordingly? Trialectic takes account of those advances, arguing that they will challenge normative theory most profoundly. If all sentient beings are the coincidence of mechanical forces, as science suggests, then it follows that the time has come to reevaluate laws grounded in theories dependent on the immaterial that distinguish the mental and emotional from the physical. Legal expert Peter A. Alces contends that such theories are misguided—so misguided that they undermine law and, ultimately, human thriving. Building on the foundation outlined in his previous work, The Moral Conflict of Law and Neuroscience, Alces further investigates the implications for legal doctrine and practice.

This Handbook serves as an authoritative reference book in the field of Neuroengineering. Neuroengineering is a very exciting field that is rapidly getting established as core subject matter for research and education. The Neuroengineering field has also produced an impressive array of industry products and clinical applications. It also serves as a reference book for graduate students, research scholars and teachers. Selected sections or a compendium of chapters may be used as “reference book” for a one or two semester graduate course in Biomedical Engineering. Some academicians will construct a “textbook” out of selected sections or chapters. The Handbook is also meant as a state-of-the-art volume for researchers. Due to its comprehensive coverage, researchers in one field covered by a certain section of the Handbook would find other sections valuable sources of cross-reference for information and fertilization of interdisciplinary ideas. Industry researchers as well as clinicians using neurotechnologies will find the Handbook a single source for foundation and state-of-the-art applications in the field of Neuroengineering. Regulatory agencies, entrepreneurs, investors and legal experts can use the Handbook as a reference for their professional work as well.​

Neurociencia y criminología Neurocriminología y neurovictimología son dos conceptos clave que forman parte de los conocimientos que todo experto en ciencias penales debe poseer, ya que los avances neurocientíficos nos muestran que los procesos de victimización tienen importantes repercusiones en el funcionamiento del cerebro, y que ello puede vulnerar los procesos cognitivos y volitivos, llegando a afectar la salud mental y las conductas de quienes sufren un delito o una violación a sus derechos humanos. A la par, hoy no podría entenderse la criminalidad sin una mirada pluridisciplinar que, desde luego, incluye el estudio del encéfalo y su relación con el ambiente. Por tal motivo, en esta obra se insiste en una actualización de los programas académicos de licenciatura y posgrado, y se explica por qué es tan necesario incluir en ellos, de manera central, las perspectivas neurobiológicas y neuropsicológicas, subrayando la relevancia de un enfoque que reconozca el valor de las interacciones socioculturales.La obra que el lector tiene en sus manos incluye una revisión de los antecedentes de estas disciplinas y plantea una prospectiva, basada en el estudio de la neurociencia y la neuropsicología, dedicada a la atención a víctimas. Neurociencia y criminología es una obra que presenta los avances más actuales en el estudio del cerebro humano y propone una ruta de trabajo aplicada a los contextos criminológicos y victimológicos de nuestras latitudes.

Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference, and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.

The concepts of the neuroendocrine system and the immune system emerged more or less simultaneously in the second half of the 20th century. Although these systems have a high degree of autonomy, it has also become clear that they interact in many ways and at different levels. This book focuses on the neuroendocrine and immune interactions that are fundamental to normal development and maintenance of health.The first introductory chapters are devoted to the historical and philosophical concepts within the field, as well as evolutionary considerations, offering critical interdisciplinary perspectives on the development of this field of research. Without attempting an exhaustive overview, the book then introduces some of the regulatory pathways that mediate interactions between the neuroendocrine and immune systems and examines modulating factors such as age and sex. In addition, several chapters address the importance of neuroendocrine-immune interactions in some disease states. Readers can expect to gain a broad perspective of neuroendocrine-immune interactions in development, health, and disease, along with a critical evaluation of current methods used in the field. Given its scope, the book is essential reading for undergraduate and graduate students with an interest in neuroendocrinology, neuroimmunology, and neuroscience, as well as postdoctoral fellows and established researchers seeking a comprehensive overview and historical perspective of the field of neuroendocrine-immune interactions.