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Completely revised and updated, the second edition of this authoritative guide provides the latest information on the diagnosis, treatment, and ongoing management of pulmonary issues in children. The book covers genetic, congenital, and allergic conditions, as well as acquired and infectious respiratory ailments. Pulmonary issues related to other systemic disorders are also covered, along with respiratory care and pediatric sleep medicine. More than 300 finely detailed images complement the text. New Second Edition Features Expanded content on sleep medicine, including sleep development and maturation, insomnia, parasomnias, sleep-related movement disorders, and obstructive sleep apnea Expanded coverage of functional respiratory disorders Cystic fibrosis newborn screening and CFTR-related metabolic syndrome Expanded coverage of pneumonia, including when caused by COVID-19 Expanded coverage of primary ciliary dyskinesia Vaping and other forms of nicotine exposure Content HighlightsFoundation—anatomy; physiology; physical examination; pulmonary testing; imaging; and bronchoscopy Allergic Conditions—bronchopulmonary aspergillosis; hypersensitivity pneumonitis; eosinophilic pneumonia; and asthma Anatomical Disorders—congenital abnormalities of the upper airway; congenital lung anomalies; and chest wall and spinal deformities Upper Airway Infections—croup, epiglottitis, and bacterial tracheitis Lower Airway Infections—bronchiectasis; bronchiolitis; viral pneumonia (including when caused by COVID-19); nonviral pneumonia; complications of pneumonia; recurrent pneumonia; tuberculosis; and nontuberculous mycobacteria Noninfectious Pulmonary Disorders—atelectasis; respiratory disorders associated with systemic inflammatory diseases; interstitial lung disease; bronchopulmonary dysplasia; pleural effusion (noninfectious); pneumothorax and pneumomediastinum; and pulmonary hemorrhage Pediatric Sleep Medicine—sleep development and maturation; obstructive sleep apnea; home sleep testing; sleep-related movement disorders; insomnia; parasomnias; narcolepsy and other disorders of excessive somnolence; sudden infant death syndrome and brief resolved unexplained events; and congenital central hypoventilation syndrome Other Pulmonary Issues—acute aspiration and aspiration-related lung disease; lung transplant; asthma and other respiratory disorders associated with obesity; and functional respiratory disorders Genetic Disorders—cystic fibrosis; cystic fibrosis newborn screening and CFTR-related metabolic syndrome; and primary ciliary dyskinesia and other genetic lung diseases Lung Disease Associated With Systemic Disorders—respiratory considerations in children with cardiac disease; lung disease associated with endocrine disorders; pulmonary complications of gastrointestinal diseases; pulmonary complications of sickle cell disease; pulmonary manifestations of oncological disease and treatment; pulmonary complications of immunologic disorders; and pulmonary complications of neuromuscular disorders Treating and Managing Pulmonary Disease—airway clearance techniques; aerosol delivery of medication; bronchodilators; antibiotics for pulmonary conditions; nutritional aspects of pulmonary conditions; oxygen therapy; and nicotine and tobacco

Developed by top pediatric hospitalists, Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, 3rd Edition, is sure to become your go-to resource from initial patient evaluation all the way through discharge management. Quickly obtain the essential information for managing a wide range of pediatric medical conditions in patients who have been admitted to the hospital with this trusted, pocket-sized reference. Each chapter not only discusses clinical presentation, essential laboratory tests, differential diagnosis, treatment, indications for consultation, and disposition but contains many helpful tables and an easy-to-follow template. Chapters also include a short bulleted list of essential pearls and pitfalls. Although the book focuses primarily on diseases and conditions, it contains helpful sections that address the many other issues practicing hospitalists are confronted with, including ethics, billing, utilization management, surge planning, and transport, as well as a brief section on common equipment. The alphabetized Contents has been updated to include Autism Spectrum Disorder, Hypertension, Constipation, Surge Planning, Utilization Management, and both Acute COVID-19 Disease and Multisystem Inflammatory Syndrome in Children (MIS-C). A new part on newborn care has been added, covering topics such as breastfeeding, hypoglycemia of the newborn, and early onset sepsis.

This third edition brings together the latest in research and clinical practice of the expanding field of pediatric neurogastroenterology. In addition to a comprehensive review of the current state of the art, many chapters have been significant revised and updated, covering the latest discoveries of the delicate and detailed mechanisms of the neuroenteric system as well as relationships of the latter with microbiota and metabolites produced by resident intestinal bacteria. The book also covers rapidly-changing techniques to assess clinical problems, along with international diagnostic criteria and recommendations and guidelines for clinical management. The content is supported by ample figures, photographs and selected video segments.Remaining the gold standard text in this up-and-coming field, Pediatric Neurogastroenterology 3e is dedicated to reporting the most accurate and recent knowledge available. Written by international experts in the field, the bookis a comprehensive and up-to-date theoretical review and practical guide to pediatric gastrointestinal motility and functional disorders to pediatricians, pediatric gastroenterologists and all professionals involved in the treatment of children with such disorders.

Keep current with the latest clinical practice guidelines and policies from the American Academy of Pediatrics (AAP), covering more than 40 conditions plus every AAP policy statement, clinical report, and technical report though December 2021. KEY FEATURESNew clinical practice guideline: Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days OldNew and revised AAP policy statements, clinical reports, and technical reportsPrinted text and eBook access, including full text of all AAP clinical practice guidelines and full text of 2021 AAP policy statements, clinical reports, and technical reportsMore than 600 policy statements, clinical reports, and technical reportsQuick Reference Tools, including coding tips, patient education handouts, and moreFive-section organization for ease of use

Movement Disorders in Childhood, Third Edition provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. In this new edition, each chapter has been fully revised to include all of the latest scientific and therapeutic advances. Updates include new insights in motor development, control, goal-directed and habitual behaviors, classifications of movements and their complex and integrated circuitry. The authors also discuss developments in pathophysiologic mechanisms, immunology and metabolic disorders. New chapters include coverage of genetics of movement disorders and movement disorders in psychiatric conditions.Appendices include an updated and revised drug index and genetic search strategy. An updated Companion website hosts selected educational videos to help diagnose movement disorders. - Provides the only current reference specifically focused on childhood movement disorders - Investigates the underlying etiologies and mechanisms of these disorders - Revised and updated with new materials and a more disease-oriented approach - Contains new chapters on the genetics of movement disorders and movement disorders in psychiatric conditions - Includes new videos of instructive and unusual childhood movement disorders

Interdisciplinary Pediatric Palliative Care provides a uniquely integrated, comprehensive resource about palliative care for seriously ill children and their families. The field of palliative care is based on the fundamental principle that an interdisciplinary team is optimal in caring for patients and their families throughout the illness trajectory. The text integrates themes including goals of care, discipline-specific roles, cultural and spiritual considerations, evidence-based outcomes, and far more. It emphasizes the value of words and high-quality communication in palliative care. Importantly, content acknowledges challenging periods between team members, and how those can ultimately benefit team, patient, and family care outcomes. Each chapter includes the perspective of the family of a seriously ill child in the form of a vignette to promote care team understanding of this crucial perspective. This second edition is founded on a wealth of evidence that reflects the innovations in pediatric palliative care science over the past 10 years, including initiatives in clinical care, research, and education. Interdisciplinary Pediatric Palliative Care is appropriate for all pediatric palliative clinicians (PPC), including physicians, nurses, psychosocial clinicians, chaplains, and many others. All subspecialists who deliver care to seriously ill children, will find this book a must-have for their work. Advance Praise for Interdisciplinary Pediatric Palliative Care, Second Edition'This new edition is as much a testament to pediatric palliative care's remarkable evolution as a field as it is a quintessential playbook for providing the high-quality holistic and compassionate care that families with seriously ill children desperately want. Every page thoughtfully weaves together how interprofessional teams can contribute collaboratively to learning about and supporting the preferences, needs and priorities of the precious patients and families in their circle of care. It is a must read for all practitioners to enhance their palliative care understanding, appreciation and ability as a foundation for optimizing quality of life in practice.'- Rebecca Kirch, JD, Executive Vice President of Policy and Programs, National Patient Advocate Foundation'This book offers a truly contemporary and comprehensive view of the entire field of pediatric palliative care. The focus on social determinants of health, cultural humility, and disparities in care could not be timelier, and the section highlighting conflict and conflict resolution should be required reading. The continued and purposeful inclusion of interdisciplinary clinicians in producing each chapter models the palliative care team itself-an approach in which all voices are necessary as we seek to provide the most compassionate care possible.'- Rachel Thienprayoon, MD, MSCS, FAAP, FAAHPM, Associate Professor of Anesthesia, Medical Director, StarShine Hospice and Palliative Care, Cincinnati Children's Hospital Medical Center

Long considered the gold standard comprehensive reference for diagnosing and managing emergent health issues in children, Fleisher & Ludwig's Textbook of Pediatric Emergency Medicine is an essential resource for clinicians at all levels of training and experience. The revised eighth edition has been updated from cover to cover, providing practical, evidence-based content to help you meet any clinical challenge in the emergency care of pediatric patients.

Comprehensive, authoritative, and up to date, Pizzo and Poplack's Pediatric Oncology, 8th Edition, remains your most trusted source of information on the care and research of children with cancer. This award-winning text is the single most comprehensive reference on the biology and genetics of childhood cancer, its diagnosis and multimodal treatment, and long-term management. In the tradition of excellence established by Drs. Philip A. Pizzo and David G. Poplack, this 8th Edition keeps you fully informed while helping you collaborate more effectively with others on the cancer care team to enhance quality-of-life issues for patients and families.

Children and infants comprise up to 20% of emergency department visits, and emergency physicians must be knowledgeable in choosing the most appropriate imaging modality to arrive at an accurate diagnosis and provide optimal patient care. Written specifically for the non-specialist and those with limited pediatric training, Pediatric Imaging for the Emergency Provider provides expert guidance in this challenging area. Abundant high-quality imaging examples cover the full range of pediatric disorders you're likely to see, including trauma, musculoskeletal, pulmonary, ENT, cardiac, genitourinary, gastroenterology, neurological, and neonatal patients. - Presents more than 80 common and important rare cases, supported with 450+ images across relevant modalities including ultrasound, radiography, CT, and MRI. - Identifies key radiographic findings for various pediatric conditions including congenital heart lesions, surgical entities, infectious disease processes, and traumatic injuries. - Accompanies images with clear, concise text that makes it easy to grasp the most clinically significant points of each case. - Provides expert guidance on best practices in important areas of pediatric imaging such as sedation, ionizing radiation exposure reduction, and imaging modality selection.

The premier comprehensive textbook in the field, Yaffe and Aranda's Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.

This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.

This handbook deals with the childhood emergencies, especially from Asian countries. Most childhood emergencies have a typical clinical presentation, but at times may reveal the uncommon presentation of a common illness or the common presentation of an uncommon illness. This book will be beneficial to every beginner in pediatrics to bring up the self-skills and confidence in managing emergencies and an added help to all pediatricians working in the peripheral hospitals shouldering great responsibility.

This book provides readers with a comprehensive review of severe asthma in children and adolescents, covering epidemiology, genetics, risk factors, co-morbidities, clinical presentation, diagnosis and treatment. Written by leaders in the field, chapter discussions draw on the mechanisms driving the disease, genetics, multidisciplinary approaches, immunomodulators, and other important aspects in the management of the disease. Severe Asthma in Children and Adolescents: Mechanisms and Management is designed to be a practical guide, opening with an introduction on the epidemiology of severe childhood asthma, as well as a discussion of special considerations of the disease unique to the preschool-aged patient. The distinctions between the diagnosis and management of asthma in young children of various ages, and specific approaches for the adolescent with severe asthma, including the transition into adult care are then addressed. Finally, the book closes with a discussion on the current state and future avenues for severe asthma research. Severe Asthma in Children and Adolescents is an indispensable reference for the healthcare professional, for basic and translational researchers, as well as for students, residents and fellows.

This is a comprehensive and authoritative textbook on pediatric pulmonology. Edited by Pablo Bertrand and Ignacio Sánchez, renowned academics and pediatricians from the Pontifical Catholic University of Chile, it encompasses five sections and 74 chapters, presenting and discussing the most important topics related to pediatric respiratory diseases. Written and presented in a simple and didactic format, it intends to ease learning and settlement of doubts in pediatric respiratory diseases. The reader is naturally introduced into the physiology, diagnosis, syndromes, diseases and the treatment associated with the respiratory pathologies affecting children. The chapters include algorithms for the treatment of various syndromes and updated treatment proposals grounded in evidence-based medicine for more than 50 pulmonary diseases. Pediatric Respiratory Diseases – A Comprehensive Textbook is an essential reference for the proper clinical approach to respiratory diseasesin children. It is intended for all interns, residents and fellows with interest in pediatric pulmonary medicine, as well as practicing physicians, general practitioners, pediatricians and pulmonologists who face pediatric respiratory disorders in daily clinical practice.

This textbook is focuses on pediatric infectious diseases. Infectious diseases contribute a major chunk of cases in our day-to-day practice. It also contributes tremendously to child mortality and morbidity. Infectious diseases are caused by microorganisms such as viruses, bacteria, fungi or parasites and can spread between individuals. This book consists of 10 chapters, which include general topics, diagnosis and management, common systemic infections, common bacterial infections, common viral infections, protozoal, parasitic and fungal infections, emerging infections, IAP guidelines/protocols, vaccines and immunization, and miscellaneous topics. The book gives latest information about the magnitude of infectious diseases burden along with the contribution of vaccine preventable diseases. Antimicrobial resistance and new infectious agents are the two main challenges in our country. Both these topics have been covered in this book. One of the important contents is the inclusion of guidelines and protocols of Infectious Diseases Chapter, which have been published in the preceding years. It enables the reader to understand the most comprehensive way to diagnose and treat the diseases which are common problems of our country. This book is useful not only to the practicing pediatricians but also to the students.

There are few publications about chemotherapy in children, and none of them is a book aimed at pharmacists. Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice. Pharmacists who work in pediatric oncology area do not have a book directed at them; none of the oncopediatric books addresses topics unique to pharmacy — such as manipulation of cytotoxic drugs for children, analysis of oncopediatric prescriptions, clinical pharmacy in oncopediatrics, pharmaceutical care in oncopediatric area, and other subjects that are of exclusive interest to these professionals, but no less essential for a therapy of excellence. As for this need, the purpose of this book is to be a guideline for all subjects that pediatric oncology pharmacists need to know to work in this area. It will be an essential guide to pediatric oncology pharmacists, clinical pharmacists, pharmaceutical residents who work with drug therapy in children and pharmaceutical researchers. It will be a pocket guide to assist in daily practice, and it will be essential to Pediatric Oncology/ Hematology Institutions. The essential propose of this book is to be the first one focusing pediatric oncology for pharmacists.

Handbook of Supportive Oncology and Palliative Care is a practical guide to providing evidence-based and value-based care to adult and pediatric cancer patients experiencing severe symptoms and stressors due to cancer diagnosis, cancer treatment, and comorbid conditions. This accessible reference provides the art and science behind the whole-person and family approach to care by delivering the best practices to relieving a cancer patient's symptoms across physical, psychosocial, and spiritual dimensions. Unlike other resources, this book covers all dimensions of palliative care but with a special emphasis on primary palliative care. Part One of the handbook provides the essential background and principles of supportive oncology and palliative care, including chapters on understanding the adult and pediatric patient and family illness experience, the roles and responsibilities of the palliative care team, and the art of the palliative care assessment interview. Part Two covers symptom management and includes ten chapters considering the major physical and psychosocial symptoms a cancer patient may face—neurologic, cardiac, respiratory, gastrointestinal, genitourinary, psychiatric, sleep and fatigue, pain, and psychosocial and spiritual distress. Part Three addresses special considerations and issues that an oncologist, physician, nurse or other healthcare provider often face in these settings, including chapters on intimacy, sexuality, and fertility issues, grief and bereavement, running a family meeting, care for the caregiver, and survivorship.Written by expert clinicians, this state-of-the-art handbook is a necessary resource for any oncologist, nurse, primary care physician, psychosocial expert, or related practitioner who endeavors to improve quality of life and provide healing to those suffering from cancer and its treatment.Key Features:Provides the binding principles of palliative care for pediatrics, adults and families from diverse cultures and spiritual beliefsEasy-to-read format makes extracting content fast and convenient for both the clinical and educational settingGuides the clinician and practitioner through the palliative care assessment process, including the appropriate questions for the palliative care interview

Now in a fully updated 9th Edition, Kendig's Disorders of the Respiratory Tract in Children, by Drs. Robert Wilmott, Andrew Bush, Robin Deterding, and Felix Ratjen, continues to provide authoritative, evidence-based information to residents, fellows, and practitioners in this wide-ranging specialty. Bringing key knowledge from global experts together in one easy-to-understand volume, it covers everything from the latest basic science and its relevance to today's clinical issues, to improving patient outcomes for the common and rare respiratory problems found in newborns and children worldwide. - Uses succinct, straightforward text, numerous tables and figures, summaries at the end of each chapter, and more than 500 full-color images to convey key information in an easy-to-digest manner. - Contains new chapters reflecting expanding knowledge on the respiratory complications of Down syndrome and other genetic disorders, modern molecular therapies for cystic fibrosis and asthma, and pulmonary embolism and thromboembolic disease. - Includes access to a new video library with demonstrations of key procedures. - Features a new templated format with more descriptive headings and bulleted text for quick reference and navigation. - Covers today's key issues, including the genetic basis of respiratory disease, new and emerging respiratory infections, interstitial lung diseases in infants and young children, technology and diagnostic techniques for pulmonary function tests, emerging lung infections, and new therapies for cystic fibrosis and asthma. - Provides up-to-date instruction on important procedures, such as bronchoscopy and pulmonary function testing. - Highlights the knowledge and expertise of three new editors, as well as more than 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This new rapid reference guide provides the latest information on common respiratory disorders seen in practice, with full coverage of asthma management, sleep disorders, and more. Includes more than 100 images to aid in problem-solving and diagnosis! Content is presented in a concise, bulleted template featuring algorithms, tables, and figures that make it easy to find key information to aid in diagnosis and treatment.Topics include:Evaluation of Children With Respiratory DiseaseAnatomic Disorders and Congenital Anomalies of the Airway, Lungs, Pulmonary Vessels, and Chest Wall Asthma and Related ConditionsInfections of the Respiratory TractPulmonary Function TestingPharmacological ManagementPulmonary and Respiratory ImagingBronchoscopyPediatric Sleep MedicineSpecial expanded sections on asthma, sleep medicine, and respiratory care provide non-specialists with the knowledge needed to effectively treat these often-complicated conditions. Each chapter is presented in a concise, bulleted format with tables and figures that make it easy to locate key information. Also included is direction on when to refer patients who require the care of a pulmonary specialist.

Cystic Fibrosis (CF) is a multisystem disease whose symptoms and signs involve the gastrointestinal tract (thus affecting nutritional status), endocrine system, reproductive system and the respiratory tract (nose, sinuses and lungs). Despite new treatments, the median survival for patients with CF is less than optimal, primarily due to complications of obstructive lung disease. Currently there are approximately 60,000-80,000 people worldwide with CF. The clinical manifestations of CF are caused by dysfunction of CFTR (cystic fibrosis transmembrane conductance regulator), a multifunctional cyclic-AMP regulated ion channel protein. Over time, there has been dramatic improvement in CF patient life expectancy, in large part related to earlier diagnosis (newborn screening), better understanding of molecular genetics and underlying pathophysiology, the integrated and highly specialized Cystic Fibrosis Foundation Accredited Care Centers, and development of a wide range of new treatments and therapies, some of which target the basic CFTR defect. This edition of Pediatric Clinics of North America will offer general pediatricians and family physicians, as well as subspecialists, an update of the extraordinary progress made in the understanding and treatment of Cystic Fibrosis.

Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world. As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the'Atopic March', along with novel ideas for potential options of prevention. - Summarizes the current knowledge of the epidemiological, genetic, and cellular basis of allergic diseases - Ideal reference for the study of allergies in young children, atopic dermatitis, allergic rhinitis, childhood asthma, and food allergies - Provides landmark findings in the field of immunology and allergy development - Fulfills the need for a book that focuses on primary and secondary allergy prevention, especially during the first years of life - Unites key, global experts in the field who summarize their collective, and current, knowledge, along with novel ideas for potential options of prevention

New Quality and Safety chapter addresses quality care for the neonatal/pediatric patient. New Clinical Highlights boxes discuss realistic scenarios to help you apply your knowledge to clinical practice. UPDATED! Over 400 full-color illustrations — plus clear tables and graphs— make it easier to visualize key concepts. New! Key point summary at end of each chapter highlights essential content in a bulleted format. New! Glossary provides easy access to key terms and their definitions. New! Key terms at the beginning of each chapter highlight important terminology.

Continuing the tradition of excellence that began in 1972, this latest edition of Tachdjian's Pediatric Orthopaedics offers the detailed visual guidance and unmatched expertise you need to effectively diagnose and treat pediatric musculoskeletal disorders. Extensive updates offer you the latest knowledge on etiology, imaging, differential diagnosis, and non-operative and surgical techniques for a wide range of pediatric orthopaedic conditions. Access expert guidance on difficult diagnostic and clinical management issues for your most challenging cases.Perfect your technique with the visual guidance of nearly 2,500 full-color illustrations and 60 videos of pediatric surgical procedures, including a number that highlight clinical examination and unusual clinical findings.Produce the best possible outcomes using today's most effective approaches for management of severe spinal deformities, hip impingement, early-onset scoliosis, and other pediatric musculoskeletal conditions.See exactly how to proceed step-by-step with instructional videos demonstrating repair of bilateral dislocated hips, triple arthrodesis for planovalgus foot, patellofemoral ligament reconstruction, elbow arthroscopy, and more. Access the full contents online at Expert Consult.

This book covers all of the important elements of paediatric anaesthesia in a concise and structured manner. From the premature infant to the teenager, readers are guided through the complexities they may encounter, with key points at the end of each chapter to summarise the most important information. The common surgical conditions encountered in daily practice are covered along with comprehensive discussion of consent and the law, safeguarding children, and the complexity of drug dosing in the paediatric population. Other topics covered include trauma, burns, resuscitation, principles of intensive care, and transporting a sick child. Each chapter is written by an acknowledged expert in their field, sharing a wealth of relevant, practical experience. Covering the whole curriculum necessary for advanced training, this is essential reading for trainees, general anaesthetists managing children in non-specialist hospitals and anyone aspiring to become a paediatric anaesthetist, as well as those established in the field.

The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology - International list of contributors including the leading workers in the field - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care

The second edition of this classic reference deals exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone that are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in children. - Deals exclusively with bone development and diseases of children and each chapter is written by an expert in the field - Fully referenced providing an appendix of usually difficult to find information on the investigation of pediatric bone disease and reference values - Covers both the physiology of bone and mineral homeostasis in children and diseases in one book

This concise textbook of pediatric surgery is designed to guide the reader logically from symptoms and signs to diagnosis and treatment. Each chapter is devoted to one of 35 key symptoms and signs, which are organized according to six body regions: head, neck, chest, abdomen, urogenital system, and back. In each case, a brief assessment of the presenting sign/symptom and differential diagnosis is followed by discussion of occurrence, clinical presentation and significance, diagnostic work-up, treatment, and prognosis. Informative tables, illustrations, and up-to-date references are included throughout. Readers will also have access to an e-learning tool developed in collaboration with the Institute of Medical Education, University of Bern, which highlights the characteristics of pediatric surgical disorders and their treatment and includes clinical, radiological, and intraoperative images.

Kendig, Chernick's Disorders of the Respiratory Tract in Children is the definitive medical reference book to help you confront critical challenges using the latest knowledge and techniques. You'll get the state-of-the-art answers you need to offer the best care to young patients.Tackle the toughest challenges and improve patient outcomes with coverage of all the common and rare respiratory problems found in newborns and children worldwide. Get a solid foundation of knowledge to better understand and treat your patients through coverage of the latest basic science and its relevance to clinical problems. Get comprehensive, authoritative coverage on today's hot topics, such as interstitial lung disease, respiratory disorders in the newborn, congenital lung disease, swine flu, genetic testing for disease and the human genome, inflammatory cytokines in the lung, new radiologic techniques, diagnostic imaging of the respiratory tract, and pulmonary function tests. Learn from the experts with contributions from 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, anesthesiology, otolaryngology, allergy, and surgery.

The book, written by expert pediatricians and radiologists, is divided into ten chapters covering neurology, cardiology, neonatology, interventional radiology, the abdomen, the musculoskeletal system, the thorax, the genitourinary system, the fetus, and emergencies. Each chapter comprises ten cases that are presented in a standard way. After discussion of the disorder in question, four representative images are displayed and described with special attention to distinctive features. In addition, informative key references are provided, including a book or book chapter, a web link, and ten recent articles.

Netter's Pediatrics, edited by Drs. Todd Florin and Stephen Ludwig, is a rich visual aid with more than 500 images by Dr. Frank Netter and other artists working in his style that will help you diagnose and care for children with common clinical conditions. This is the first time that Netter's drawings of pediatric illness are brought together in a single volume. The superb, accurate artwork accompanies up-to-date text contributed by physicians at the prestigious Children's Hospital of Philadelphia. The book provides you with all the at-a-glance information you need for a quick overview of common issues from nutrition, allergy, infectious disease, and adolescent medicine, to cancer and heart disease. This user-friendly, clinical reference is also a great tool for patient and staff education. - Efficiently review key details for each condition with 500 detailed, crystal-clear images provided by Frank H. Netter and others working in the Netter tradition. - Apply dependable, concise, clinical advice from a team of physicians at Children's Hospital of Philadelphia, one of the top children's hospitals in the U.S. - Get answers at a glance during pediatric rotations when studying for exams or preparing for consultations.

Pediatric Anesthesia: Basic Principles—State of the Art—Future contains the contributions of 220 international experts from all five continents. This is the only textbook of its kind that has such a strong international representation of the very best authorities in the field.

You'll turn here often for the latest AAP findings and recommenations; assessment and testing how-tos; proven therapeutic strategies; procedures, and techniques; home care and monitoring considerations; and much more. Powerful problem-solving features in each information-rich chapter include illustrative case reports, key point summaries; and definitions of pulmonary-specific terms. Nearly 300 finely detailed images complement the text. Content highlights: - Foundation knowledge and know-how - anatomy and physiology; physical examination; pulmonary testing; imaging; bronchoscopy- Allergic conditions - acute bronchopulmonary aspergillosis; asthma- Anatomical disorders - congenital anomalies; chest wall and spinal deformities- Upper airway infections - croup, epiglottitis, and bacterial tracheitis- Lower airway infections - bronchiectasis; bronchiolitis; community-acquired pneumonia; complications of pneumonia; tuberculosis- Noninfectious pulmonary disorders - interstitial lung disease; bronchopulmonary dysplasia; pleural effusion; pneumothorax and pneumomediastinum; pulmonary hemorrhage; aspiration- Miscellaneous pulmonologic issues - lung transplantation; pulmonary disorders associated with obesity; functional respiratory disorders; sleep disorders- Genetic disorders - cystic fibrosis; primary ciliary dyskinesia- Lung disease associated with systemic disorders - pulmonary complications of cardiac disease; endocrine disorders; GI disorders; sickle cell disease; immunodeficiency disorders; neuromuscular disorders; cancer- Treating and managing pulmonary disease - airway clearance techniques; medication delivery; bronchodilators; antibiotics and corticosteroids; oxygen therapy; preventing and treating tobacco dependence; home monitoring; home ventilation

This book provides a detailed account of intellectual, other neuropsychological and behavioral manifestations of general pediatric diseases. The conditions discussed include the whole range of pediatric diseases - genetic syndromes, other congenital conditions, metabolic, endocrine, gastrointestinal, infectious, immunologic, toxic, trauma, and neoplastic, as well as sensory disabilities including deafness and blindness. Although the book is not intended to discuss cognitive and behavioral manifestations of conditions usually considered to be primary neurological disease, some of those, including cerebral palsy, muscular dystrophy, myotonic dystrophy and epilepsy, are included. Where possible, a'translational'approach is used, linking the behavioral and cognitive manifestations of these conditions, to the underlying structural, chemical or genetic abnormalities and their effect on the brain, and, in turn, on behavior and cognition. At the same time, included are significant psychosocial factors. Together, those factors have a major effect on patients'performance, including school performance, and on their families. This book is unique in its extensive coverage of the major pediatric conditions and of the detailed neurological, neuropsychological and behavioral aspects of each condition.

Written by child neurologists, this comprehensive, multi-authored volume on autism systematically discusses the classification, epidemiology and neurobiology of autism. Autism lacks a unique etiology or specific pathology, so the behaviorally defined social deficits, language impairments and repetitive behaviors that define autism are explored from a developmental neurology perspective. The evidence suggesting that autism is a disorder of neuronal development is reviewed by experts on the genetics, neuroanatomy and neuroradiology, neurochemistry, immunology, and neurophysiology of autism. Chapters provide comprehensive reviews of the common neurological problems associated with autism such as epilepsy, sleep disturbances and motor and sensory deficits. Neuropsychological assessment, medical and psychopharmacologic management, educational and behavioral interventions, and outcome are discussed within the clinical content of the practising neurologist. The research agenda needed to understand the neurology of autism is emphasized throughout the book and in the conclusion. International Review of Child Neurology Series No. 7 Written by child neurologists, this comprehensive, multi-authored volume on autism systematically discusses the classification, epidemiology and neurobiology of autism. Autism lacks a unique etiology or specific pathology, so the behaviorally defined social deficits, language impairments and repetitive behaviors that define autism are explored from a developmental neurology perspective. The evidence suggesting that autism is a disorder of neuronal development is reviewed by experts on the genetics, neuroanatomy and neuroradiology, neurochemistry, immunology, and neurophysiology of autism. Chapters provide comprehensive reviews of the common neurological problems associated with autism such as epilepsy, sleep disturbances and motor and sensory deficits. Neuropsychological assessment, medical and psychopharmacologic management, educational and behavioral interventions, and outcome are discussed within the clinical content of the practising neurologist. The research agenda needed to understand the neurology of autism is emphasized throughout the book and in the conclusion. International Review of Child Neurology Series No. 7