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Hugo & Russell's Pharmaceutical Microbiology Discover the very latest developments in pharmaceutical microbiology in the 9th edition of this popular textbook Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field. The 9th edition of Hugo and Russell's Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers. In this ninth edition of Hugo and Russell's Pharmaceutical Microbiology, readers will find: A mix of established and new authors bringing practical and research experience to their chapters Material covering the fundamentals of microbiology, microbial behavior and laboratory investigation Revised chapters incorporating new material on microbe-host interactions, antibiotic resistance, emerging pathogens, public health microbiology, healthcare-associated infection and pharmaceutical manufacture Emerging understandings from the COVID-19 pandemic on infection prevention and control and vaccine development Practitioners providing their insights on clinical practice and pharmaceutical production An accompanying website incorporating teaching resources Hugo and Russell's Pharmaceutical Microbiology, 9th edition promises to remain the essential text for pharmacy and medical students, as well as researchers and industry professionals.

This second edition of Studies in Viral Ecology is designed to serve as a means of updating the knowledge of virologists regarding the broader aspects of viral ecology. As with the first edition, this book explains the ecology of viruses by examining their interactive dynamics with their hosting species (covering both animals and plants), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized.This second edition of Studies in Viral Ecology is designed to serve as a means of updating the knowledge of virologists regarding the broader aspects of viral ecology. As with the first edition, this book explains the ecology of viruses by examining their interactive dynamics with their hosting species (covering both animals and plants), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized. Now in its second edition, Studies in Viral Ecology explores the intricate interactions between viruses and other organisms from a “virocentric” perspective. Divided into five sections, the book opens with a thorough introduction to the ecology of all viruses, followed by detailed examinations that individually consider the viruses of other microorganisms, viruses of vascular plants, and viruses of vertebrate and invertebrate animals. The chapters have been written by leading scientists in their respective research fields and cover topics such as the evolution of fungal viruses, viruses affecting insects, viruses of terrestrial and marine mammals, and the relationship between humans, their viruses, and prions. Studies in Viral Ecology, Second Edition remains required reading for virologists and virology instructors and students who study the interactions between virus and host at the individual species and higher taxonomic levels.

A comprehensive guide to providing effective dental treatment and care to patients affected by diseases Essentials of Human Disease in Dentistry, Second Edition takes an integrated approach to dentistry and how it relates to general medicine, surgery, pharmacology, therapeutics, pathology and microbiology. Building on the success of the Textbook of Human Disease in Dentistry, this new edition has been updated with a new layout, featuring key topics, learning objectives and practical clinical advice in each chapter. This accessible guide is structured around the systems of the body and covers all major diseases and conditions with their aetiology, symptoms, and treatments. The focus is on the relevance of particular diseases and their drug treatment in relation to dentistry and patient dental management. This vital resource: Promotes a better understanding of how to provide effective dental treatment to patients affected by diseases Presents illustrative examples and helpful clinical photographs throughout Includes a new chapter on the importance of understanding shock Features self-assessment questions at the end of each chapter, and a companion website hosting downloadable images from the book Essentials of Human Disease in Dentistry, Second Edition is an invaluable resource for undergraduate dentistry students as well as newly qualified dentists preparing for the MFDS exam.

A FASCINATING AND INFORMATIVE EXPLORATION OF PERIGLACIAL PROCESSES, PAST AND PRESENT, AND THEIR ROLE IN LANDSCAPE EVOLUTION Periglacial Geomorphology presents a comprehensive introduction to the processes that operate in present periglacial environments and discusses the inferences that can be drawn about former periglacial environments from those processes. Organized into six parts, the book opens with the historical and scientific context of periglacial geomorphology and the nature of periglacial environments. Following chapters provide systematic coverage of the full range of topics germane to a thorough understanding of periglacial geomorphology, including: The physics of ground freezing and thawing, characteristics of permafrost, and the nature and origin of underground ice Characteristics, formation and significance of landforms, sediments, and structures associated with permafrost, permafrost degradation, and seasonal ground freezing and thawing Rock weathering in periglacial environments, periglacial processes operating on hillslopes, and the characteristic landforms produced by rock breakdown and slope processes in cold environments The operation of fluvial, aeolian and coastal processes in cold environments, and the resulting distinctive landforms and sediments The use of relict periglacial features to reconstruct past cold environments in midlatitude regions and the responses of periglacial environments to recent and predicted climate change Periglacial Geomorphology is an important resource for undergraduate and graduate students studying geomorphology or Quaternary science within the context of geography and geology degree programs. It will be of use to all scientists whose research involves an understanding of cold environments, whether from a geographical, geological, ecological, climatological, pedological, hydrological, or engineering perspective.

The celebrated lower Cambrian Chengjiang biota of Yunnan Province, China, represents one of the most significant ever paleontological discoveries. Deposits of ancient mudstone, about 520 million years old, have yielded a spectacular variety of exquisitely preserved fossils that record the early diversification of animal life. Since the discovery of the first specimens in 1984, many thousands of fossils have been collected, exceptionally preserving not just the shells and carapaces of the animals, but also their soft tissues in fine detail. This special preservation has produced fossils of rare beauty; they are also of outstanding scientific importance as sources of evidence about the origins of animal groups that have sustained global biodiversity to the present day. Much of the scientific documentation of the Chengjiang biota is in Chinese, and the first edition of this book was the first in English to provide fossil enthusiasts with a comprehensive overview of the fauna. The second edition has been fully updated and includes a new chapter on other exceptionally preserved fossils of Cambrian age, exciting new fossil finds from Chengjiang, and a phylogenetic framework for the biota. Displaying some 250 figures of marvelous specimens, this book presents to professional and amateur paleontologists, and all those fascinated by evolutionary biology, the aesthetic and scientific quality of the Chengjiang fossils.

A thorough introduction to the basics of bioengineering, with a focus on applications in the emerging'white'biotechnology industry. As such, this latest volume in the'Advanced Biotechnology'series covers the principles for the design and analysis of industrial bioprocesses as well as the design of bioremediation systems, and several biomedical applications. No fewer than seven chapters introduce stoichiometry, kinetics, thermodynamics and the design of ideal and real bioreactors, illustrated by more than 50 practical examples. Further chapters deal with the tools that enable an understanding of the behavior of cell cultures and enzymatically catalyzed reactions, while others discuss the analysis of cultures at the level of the cell, as well as structural frameworks for the successful scale-up of bioreactions. In addition, a short survey of downstream processing options and the control of bioreactions is given.With contributions from leading experts in industry and academia, this is a comprehensive source of information peer-reviewed by experts in the field.

Neuromodulation in Psychiatry Neuromodulation in Psychiatry This is the first comprehensive and detailed reference work that focuses on neuromodulation strategies in psychiatry. Neuromodulation strategies are no longer confined to tertiary hospitals but are used in community practices and even by individual psychiatrists. Surgery for psychiatric disorders is one of the main advances in the field of functional neurosurgery. Neuromodulation in psychiatry includes chapters on the history of this controversial field and the ethics of modern usage of such techniques. Specific chapters are devoted to neuromodulation and surgical strategies used in psychiatry including transcranial magnetic stimulation, transcranial direct current stimulation, vagus nerve stimulation, direct cortical stimulation and deep brain stimulation. A chapter describes the basic principles of each techniques, using figures and schematics to illustrate details for people who do not have personal experience of using these techniques. Another chapter then focuses on the results of clinical research, trials and applications for that strategy. Written by an expert multidisciplinary editorial team across the fields of neurosurgery, psychiatry and neurology, this title: Encompasses basic principles, technical aspects and clinical applications including ethical considerations Clearly explains each technique with implications for clinical practice Presents evidence in a comprehensive summary suitable for all levels Allows psychiatrists to evaluate results obtained using such strategies and to make decisions regarding the best course of treatment for their patients An essential reference guide for psychiatrists, psychologists neurosurgeons, neurologists and respective trainees. The book is the first comprehensive reference work to cover all neuromodulation strategies now used or with potential use in psychiatry. It allows psychiatrists to evaluate results obtained using such strategies and to make decision regarding the best course of treatment for their patients.

Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today's neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers• Both print and enhanced e-book versions are available• Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology', a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA

Highly Commended at the British Medical Association Book Awards 2016Abdominal X-rays for Medical Students is a comprehensive resource offering guidance on reading, presenting and interpreting abdominal radiographs. Suitable for medical students, junior doctors, nurses and trainee radiographers, this brand new title is clearly illustrated using a unique colour overlay system to present the main pathologies and to highlight the abnormalities in abdomen x-rays. Abdominal X-rays for Medical Students: Covers the key knowledge and skills necessary for practical use Provides an effective and memorable way to analyse and present abdominal radiographs - the unique'ABCDE'system as developed by the authors Presents each radiograph twice, side by side: the first as seen in the clinical setting, and the second with the pathology clearly highlighted Includes self-assessment to test knowledge and presentation technique With a systematic approach covering both the analysis of radiographs and next steps mirroring the clinical setting and context, Abdominal X-rays for Medical Students is a succinct and up-to-date overview of the principles and practice of this important topic.

Written by leading experts in the field, Cyanobacteria: An Economic Perspective is a comprehensive edited volume covering all areas of an important field and its application to energy, medicine and agriculture. Issues related to environment, food and energy have presented serious challenge to the stability of nation-states. Increasing global population, dwindling agriculture and industrial production, and inequitable distribution of resources and technologies have further aggravated the problem. The burden placed by increasing population on environment and especially on agricultural productivity is phenomenal. To provide food and fuel to such a massive population, it becomes imperative to find new ways and means to increase the production giving due consideration to biosphere's ability to regenerate resources and provide ecological services. Cyanobacteria are environment friendly resource for commercial production of active biochemicals, drugs and future energy (biodiesel, bioethanol and hydrogen). Topics on isolation, identification and classification of cyanobacteria are discussed, as well as further sections on: summarizing a range of useful products synthesized by cyanobacteria, ecological services provided by cyanobacteria including their harmful effect in water bodies and associated flora and fauna. Chapter on tools, techniques, and patents also focus on the economic importance of the group. This book also provides an insight for future perspectives in each particular field and an extensive bibliography. This book will be a highly useful resource for students, researchers and professionals in academics in the life sciences including microbiology and biotechnology.

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells.Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals.

This book explains the ecology of viruses by examining their interactive dynamics with their hosting species (in this volume, in animals), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized.

This book explains the ecology of viruses by examining their interactive dynamics with their hosting species (in this volume, in microbes and plants), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles, and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized.

Pharmaceutical microbiology has a bearing on all aspects of pharmacy, from the manufacture and quality control of pharmaceutical products through to an understanding of the mode of action of antibiotics. Fully revised and restructured, drawing on the contributions of subject experts, and including material relevant to the European curricula in pharmacy, the eighth edition covers: biology of micro-organisms pathogens and host response prescribing therapeutics contamination and infection control pharmaceutical production current trends and new directions Hugo and Russell's Pharmaceutical Microbiology, a standard text for Schools of Pharmacy for seven editions, continues to be a user-friendly and authoritative guide for both students and practitioners of pharmacy and pharmaceutical microbiology.'Highly Commended'in the Pharmacology section of the 2012 BMA Book Awards

The Textbook of Human Disease in Dentistry is a comprehensive resource for all students of dentistry that provides uniquely integrated coverage of medicine, surgery, pharmacology, therapeutics, pathology and microbiology. It aims to provide its readers with the medical context of dentistry, to promote better understanding of how to provide effective dental treatment to patients affected by diseases and conditions. The Textbook of Human Disease in Dentistry is structured around the systems of the body and includes chapters on immunological disease, cardiovascular diseases, respiratory medicine, gastroenterology, dermatology, musculoskeletal disorders and neurological and special senses. A key aspect of the book is the relevance of particular diseases and/or their drug treatment to dentistry and in turn to patient dental management. Additional chapters are therefore provided on topics such as clinical examination and history taking, inflammation and anti-inflammatory drugs, infection control, pain and anxiety control, and care of the elderly. Filled with useful features and written in a lucid and accessible style, this book will provide its readers with a sound and accessible grounding in human diseases and their drug treatment and how they relate to dental care. Includes sections on all major diseases and conditions, describing aetiology, symptoms and treatment Places dentistry in a medical context, providing guidance on examination and treatment protocols Features information on drug treatment and planning dental care around it Illustrated with helpful clinical photographs, showing diseases and conditions

Radiofrequency Catheter Ablation of Cardiac Arrhythmias has been so extensively updated for its third edition that the book now features a new title: Catheter Ablation of Cardiac Arrhythmias: Basic Concepts and Clinical Applications. The editors bring you 21 polished chapters, each updating the fundamentals and progressing to advanced concepts, providing state-of-the-art knowledge with highly relevant material for experienced electrophysiologists as well as fellows in training. This streamlined new edition features: • Two new editors, both widely published and leaders in the field of catheter ablation • 21 instead of 39 chapters, achieved by focusing on primary topics of broad interest and assimilating information from a wide range of sources • Fewer authors, chosen for their recognized contributions to the topics under discussion, providing a more integrated and coherent approach • Anatomic insights from leading pathologist Siew Yen Ho, integrated with new information from imaging technologies Each chapter dealing with ablation of a specific arrhythmia features the author's personal approach to ablation of the arrhythmia, including practical'how-to'tips, and a review of potential pitfalls. Alternate approaches and variations are succinctly summarized. Original figures and drawings illustrate specific approaches to improve the usability of the book.

This authoritative guide provides a basis for understanding the emerging technology of ground source heat pumps. It equips engineers, architects, planners, regulators and geologists with the fundamental skills needed to manipulate the ground's huge capacity to store, supply and receive heat, and to implement technologies (such as heat pumps) to exploit that capacity for space heating and cooling. The author has geared the book towards understanding ground source heating and cooling from the ground side (the geological aspects), rather than solely the building aspects. An Introduction to Thermogeology: Ground Source Heating & Cooling explains the science behind thermogeology and offers practical guidance on different design options.

This best selling text has been completely revised and refreshed in the fourth edition. The authors aim to enthuse family doctors (for whom they are primarily writing) to enjoy the challenge of diagnosing and treating skin conditions. Clinical Dermatology contains over 500 high quality pictures and diagrams matched with many colourful phrases to illustrate and entertain as it teaches. It has established a reputation as a ‘way of learning'and as a cogent overview of the subject for the aspiring specialist. Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment. The authors have created an easily read text with enough detail to clarify the subject but not enough to obscure it. This fourth edition contains new chapters on racially pigmented skin, dermatology of different age groups and cosmetic dermatology. Relevant internet sites are now clearly highlighted at the end of each chapter and the comprehensive formulary has been updated.

This is a new and completely rewritten edition of the well-known text Microfossils (first published in 1980) covering all the major microfossil groups, with information on taxonomy, phylogeny, ecology and palaeoecology. particular attention is given to the uses of microfossils in environmental reconstruction and biostratigraphy numerous line and half-tone illustrations emphasis on practical applications of micropalaeontology only student-friendly micropaleontology text available

Advanced Urologic Surgery is a stimulating operative atlas which includes the latest innovations, modifications, and improvements in the field, edited by a distinguished international team. The text is divided into sections; kidney and ureter bladder prostate external genitalia female urology urinary diversion special techniques It is further divided into sub-sections, each devoted to a specific urologic operative procedure, graded according to its standardisation and acceptance by the wider surgical community. The text is descriptive and is complimented by over 800 clear operative line illustrations providing a step-by-step approach. The end result is an exciting survey of the practical applications of the latest techniques. Joining Professor Hohenfellner as Editor is Professor John Fitzpatrick, one of the most prominent figures on the world urology scene and the editor of leading urology journal, BJU International. In addition to John Fitzpatrick, the book will feature Professor Jack McAninch from the USA as an editor. Jack McAninch based at San Francisco General Hospital, is one the true giants of American urology, current President of the Societe Internationale d'Urologie, and past President of the American Urological Association. All chapters include a list of key references explaining the practical application of the latest techniques in urologic surgery - essential reading for urologists in both practice and training.

This publication presents the structure and function of biological membranes to improve the understanding of cells in both normal and pathogenic states. Recently, vast amounts of new information have been accumulated, especially about pathological conditions, and there is now much evidence correlating genotypes and phenotypes in normal and disease states. This book surveys the most recent findings in research on the molecular biology, biochemistry, and genetics of the membranes of human red blood cells.

The Encylopaedia of Molecular Biology is a truly unique work of reference. 6000 definitions cover the entire spectrum of molecular life science The complete one-volume guide to understanding the way molecular biology is transforming medicine and agriculture Long and short entries written by over 300 of the world's finest researchers For rapid research or detailed study... this is the A to Z of the New Biology