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The book delves into various aspects of the hair care industry, providing a comprehensive understanding of hair throughout history, its anatomy and physiology, genetics and molecular mechanisms of hair color, and the raw materials used in the industry. It explores the diverse range of hair care products, including oils, dyes, lotions, and serums, and emphasizes the importance of global regulatory approaches to ensure consumer health and safety, particularly in relation to nano-formulations and synthetic hair care products. The book also addresses the safety and efficacy of herbal care products from a global regulatory perspective. Furthermore, it examines the impact of the microbiome on hair care products, highlighting the opportunities and challenges in complying with global regulations. The evaluation of hair care product safety is discussed within a global context, exploring different models and methods. The book also focuses on the journey of hair care products from laboratory testing to market, emphasizing clinical and preclinical assessments in compliance with global regulations. It highlights the role of ex-vivo hair follicle models in ensuring the safety and effectiveness of hair care products while providing a global regulatory framework. Additionally, the book explores the potential of artificial intelligence in predicting hair product toxicity, taking a global perspective. It delves into omics approaches for hair toxicity assessment, discussing current advances and future directions in this field. The next generation of hair products is also explored, with a focus on innovations that prioritize safe and healthy consumer choices. Finally, the book provides an overview of global regulatory frameworks for the hair care industry, including key agencies and guidelines. It serves as a valuable resource for professionals and researchers in the field, offering insights into the historical, scientific, and regulatory aspects of hair care products and their impact on consumer health and safety.

Encyclopedia of Toxicology, Fourth Edition is the most extensive compendium surveying the full scope of toxicology, including its chemical, biological and physical (e.g., radiation) perspectives. Spanning nine volumes, this new edition comprises 1150 thoroughly revised and 70 entirely new entries authored by experts in their respective fields, selected by a globally recognized board who have brought rigorous editorial skills to the project. New areas covered in this release include the bourgeoning field of computational toxicology, research applications of alternatives to animal testing, the rise in development and use of consumer products and their effects on populations, and the increasing introduction and use of pharmaceutical ingredients and their interactions. Other chapters of note cover artificial intelligence models of toxicological exposure and effects, extractables and leachable testing, climate change implications for humans, animals and the environment, screening models, -omics, tools such as sequence alignment to predict across species susceptibility, and much more. - Includes contributions from a world-renowned editorial board and expert contributors with wide-ranging backgrounds in toxicology - Thoroughly updated with the latest advances in the science - Contains concise and accessible content, providing an authoritative reference resource for non-specialists and readers from undergraduate level upwards, as well as advanced healthcare providers - Covers new topics such as computational toxicology, alternatives to animal testing, pharmaceutical ingredients, artificial intelligence models of toxicological exposure and effects, wildfires and effects of their smoke, vaping, high throughput transcriptomics, and the effect of environmental chemicals on the microbiome