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Managing the Complications of Cirrhosis: A Practical Approach is a simple pocket guide for the community gastroenterologist and primary-care provider who manages liver disease.While there are other books available on the market regarding the management of cirrhosis, this reference includes information geared toward the busy practitioner, allowing the reader to reference a chapter that easily addresses the clinical issue at hand. Dr. Atif Zaman provides essential and current information on the management of cirrhosis for the nonhepatologist.Each chapter in Managing the Complications of Cirrhosis: A Practical Approach is broken down into four sections, including a summary of the issue at hand, a diagnosis of the problem, a treatment algorithm, and what to do if the treatment algorithm is ineffective. In addition, each chapter highlights complex cases that have no standard treatment, but have emerging concepts or data.Chapter topics include: Preventative health issues in patients with cirrhosis Nutrition in patients with cirrhosis Management of hepatocellular carcinoma Pulmonary issues in patients with cirrhosis Timing of referral for liver transplant With algorithms and tables, Managing the Complications of Cirrhosis: A Practical Approach is the perfect book for all community gastroenterologists, primary-care practitioners, medical residents and fellows, physician assistants, and nurse practitioners who provide care in the area of liver disease.

The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number — from fewer than 25 in 1968 — to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.

- NEW! Coverage of high-flow nasal oxygen therapy and both core and advanced concepts for mechanical ventilation helps you deliver high-quality care to patients with respiratory failure. - NEW! Chapters on current critical care topics include Assessment of Intravascular Volume, Urine Osmolality and Electrolytes, and Infectious Disease Control in the ICU. - NEW! Chapters on novel procedures offer coverage of tracheal stents, urinary diversion techniques, and an in-depth review of point-of-care ultrasound with extensive figures and images. - NEW! Coverage of increasingly prevalent problems seen in the intensive care unit includes coagulation disorders of the critically ill patient, feline aortic thromboembolism, oxygen toxicity, and treatment of severe hypertension. - NEW! Chapters on shock fluid therapy and transfusion therapy provide cutting edge information on how to prevent complications and maximize resources. - NEW! Prevention of Compassion Fatigue and Burnout chapter addresses this major challenge currently affecting the veterinary profession. - NEW! Algorithms and figures throughout the text clarify key concepts and aid in diagnosis and treatment. - NEW! Enhanced eBook, included with the purchase of a new print copy of the book, provides online access to a fully searchable version of the text and makes its content available on various devices. - UPDATED! Coagulation section includes chapters on hemostasis, management of the bleeding patient, coagulation and platelet monitoring, and viscoelastic monitoring. - EXPANDED! Pharmacology section offers coverage of cannabis, trazadone, gabapentin, pimobendane, and appetite stimulants.

Understanding and addressing the current opioid crisis requires knowledge of endogenous opioids (endorphins and enkephalins), but there is now evidence for a benzodiazepine crisis. Are there endogenous benzodiazepine-like substances—and what do they do? How do they affect antianxiety drugs and their adverse effects? Do they explain enigmatic prolonged benzodiazepine withdrawal syndrome? This book raises important questions about the clinical consequences of ignoring the existence of or understanding the potential influence of endogenous benzodiazepines on the therapeutic effect of benzodiazepines, their adverse effects, and the problems of withdrawal from them and other benzodiazepine receptor agonists.FEATURES Discusses endogenous benzodiazepine-like substances—what do they do, and do they affect antianxiety drugs and their adverse effects? Presents information on enigmatic prolonged benzodiazepine withdrawal syndrome Describes the compounds acting at the BDZ binding sites, both exogenous (classical BDZ drugs and BDZ from food and plants) and endogenous (endozepines) Assesses the putative interactions in physiology, pathology, and pharmacology of the compounds acting at the BDZ binding sites Dr. Raffa is Adjunct Professor at the University of Arizona College of Pharmacy and Professor Emeritus at Temple University School of Pharmacy. He has co-authored or edited several books on pharmacology and thermodynamics, is a co-editor of two journals, is a past president of the Mid-Atlantic Pharmacology Society, and is the recipient of research and teaching awards. Dr. Amantea is Associate Professor of Pharmacology at the Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria (Italy), where she is the leader of the Stroke Research Unit at the Section of Preclinical and Translational Pharmacology operating in the frame of the Italian Stroke Organization (ISO) Basic Science. She is a member of the Editorial Board and the Guest Editor of the 2016 Neuroscience section of Current Opinion in Pharmacology (Elsevier), and the founder and the editor of the CRC Press Frontiers in Neurotherapeutics series.