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Abuse of synthetic opioid prescription painkillers such as fentanyl, along with a rapidly growing list of illicit analogues, is a significant public health problem. In this study, we developed a simple dilute-and-shoot method that provides a fast 3.5-min analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and sufentanil) in human urine by liquid chromatography-tandem mass spectrometry (LC-MS/MS) using a Raptor Biphenyl column. [ABSTRACT FROM AUTHOR]

The article offers information on post-operative pain for British nurses. Topics include the percentage of people who will experience severe pain post-operatively according to the National Institute for Health and Care Excellence, NICE's March 2016 advice on managing moderate to severe post-operative pain using the sufentanil sublingual tablet system, and the need for clear protocols for the management of acute pain by ward staff.