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"Have a Good Trip: Exploring the Magic Mushroom Experience" by Eugenia Bone is a nonfiction book that delves into the science and benefits of psilocybin mushrooms. The author explains how psilocybin is metabolized in the body and activates neural circuits in the brain, resulting in a tripping sensation. While Bone includes formal studies, she also relies on anecdotal evidence to fill gaps in scientific research. The book explores personal stories of individuals who have used magic mushrooms for various purposes, such as overcoming compulsive behaviors and dealing with grief. Bone also shares her own experiences with the drug, including participating in a mushroom ceremony in Mexico. The book offers a unique blend of scientific research, personal narratives, and the author's own experiences, providing readers with an eclectic and stimulating study on the topic. [Extracted from the article]

In "Psychedelic Outlaws: The Movement Revolutionizing Modern Medicine," Joanna Kempner explores the efforts of individuals and organizations to legitimize and legalize the medical use of psychedelic drugs such as LSD and psilocybin mushrooms. The focus of the book is on Clusterbusters, an online community for individuals suffering from cluster headaches. Kempner profiles key figures in Clusterbusters' campaign, highlighting collaborations between patients and medical professionals that are reviving scientific interest in psychedelic therapies. The book also provides historical context, discussing how moral panics in the past hindered research on the medical applications of drugs like MDMA and LSD. [Extracted from the article]

In "Psychedelic Revival: Toward a New Paradigm of Healing," therapist Sean Lawlor explores the history and potential benefits of psychedelic healing. He discusses the use of substances like psilocybin and ayahuasca in Indigenous healing ceremonies and their recent resurgence in Western scientific research. Lawlor cautions against viewing psychedelics as a magical cure-all and emphasizes the importance of active engagement in the healing process. While the book covers a wide range of topics and tones, it offers intriguing insights for readers interested in the subject. [Extracted from the article]

The article presents a study which utilized a charge modulated iHILIC-Fusion hydrophilic interaction liquid chromatography (HILIC) column for the analysis of extracts from hallucinogenic mushrooms and evaluated its potential for forensic application. Topics include psychoactive compounds contained in hallucigenic mushrooms, importance of the reliable quantification of these compounds, and finding on iHILIC-Fusion.

The article examines the potential to use psychedelic compounds clinically. Particular focus is given to ibogaine, 3,4-methylenedioxy-methamphetamine (MDMA), marijuana, ketamine and psilocybin. Other topics include the efforts by researchers to investigate the potential to use psychoactive compounds in the treatment of mental health disorders such as schizophrenia and depression, and the potential applications of psychedelic compounds such as treating addiction, neuropathic pain and epilepsy.

The article lists the journal's top chemistry reports in 2017 including the research on the medical application of the biosynthetic pathway of psilocybin mushroom, the booming supply of equipment use to measure air quality in China, and the risk of watching solar eclipse without eye protection.

In this study, a solid-phase extraction (SPE) procedure is described that isolates both psilocybin and psilocin from urine samples. Extraction was performed using a mixed-mode SPE column. Samples of urine were diluted with aqueous phosphate buffer (pH 6). After the sample was applied to the SPE column, the sorbent was washed with deionized water and methanol. The analytes were eluted from the SPE column with 3 ml of ethyl acetate containing 2% ammonium hydroxide followed by 3 ml of methanol containing 4% ammonium hydroxide. The individual eluates were collected, evaporated to dryness, and dissolved in mobile phase (50 p1) before being combined for analysis by liquid chromatography-tandem mass spectrometry (LC-MS-MS). Chromatography was performed in gradient mode using a (18 column and a mobile phase consisting of acetonitrile and 0.1% aqueous formic acid. The total run time for each analysis was <5 mm. The limits of quantitation or detection for this method were determined to be 10 ng/ml and 5 ng/ml for both psilocybin and psilocin, respectively. The method was found to be linear from 10 ng/ml to 1000 ng/ml (r²> 0.995) for both compounds (psilocybin and psilocin). Recoveries of the psilocybin and psilocin were found to be greater than 85%. [ABSTRACT FROM AUTHOR]

The article reviews the functional superfood beverage, Organic Instant Mushroom Coffee from the Z Natural Foods.

The article informs that researchers at the Friedrich-Schiller-Universität Jena in Germany unravel the biosynthesis of the psychoactive drug psilocybin, making large-scale production a possibility for medical uses, which include treating anxiety and depression and treating nicotine addiction.

The article reports on scientists' confirmation that the psychedelic agent in Psilocybe mushrooms called psilocybin elicits mystical experiences in some people and "bad trips" in others. A study on the effects of psilocybin was monitored to help in the management of fear, anxiety and other ill effects experienced by participants.