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Why you should read this article: • To update your knowledge of the effective administration of intramuscular (IM) injections • To refresh your memory of the vital elements of the procedure such as selecting the appropriate injection site and using the appropriate equipment • To understand the importance of patient assessment when undertaking IM injections Administering medicines by intramuscular (IM) injection is a familiar, though not necessarily common, nursing procedure. To ensure effective administration of IM injections it is important that nurses are up to date with the evidence on factors such as selection of injection site, use of appropriate equipment and injection technique. This article explores the evidence on effective administration of IM injections with the aim of enhancing nurses' decision-making and technique when undertaking this procedure. [ABSTRACT FROM AUTHOR]