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The article discusses the importance of valid quality of life (QOL) questionnaires in treating patients with ocular allergy and how this condition impacts the patient's everyday life. Topics include the guidance from the U.S. Food and Drug Administration on the development and implementation of patient reported outcomes (PROs) in clinical trials, the development of QoL questionnaires through strict statistical analysis of validity, and telephone and online surveys.

A reprint of the article "LC Columns — The Top-10 List: Want to improve column life? Here are some ideas.," by John W. Dolan, which appeared in the November 2004 issue of "LC-GC North America," is presented. Topics discussed include equations for estimation of liquid chromatography (LC) parameters, system suitability test for validation of analytical method and equipment, and incorporation of quality control (QC) samples.

The article illustrates how scientifically based research (SBR) works using peppermint chocolates. The study title is "Construct Validity and the Interpretation of Different Hypotheses and Errors of Inference in the Effects of Peppermint Patties on the Work Habits of Information Professionals: An Empirical Confirmatory Study." Principles of a research study include posing questions that can be investigated empirically, and associating research with relevant theory.

The article reports on the massive cheating of certification exams of software vendors online. The activities of exam thieves has created problems for technology vendors, students, and IT workers who legitimately passed the tests. In a survey by the Association of Test Publishers in Washington, it was found out that about half of the companies surveyed notified that their exams were being cheated and available for sale on the Internet. The author describes some of the proposed measures by some companies to prevent the said practice.