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Fetal exposure in adverse environmental factors during intrauterine life can lead to various biological adjustments, affecting not only in utero development of the conceptus, but also its later metabolic and endocrine wellbeing. During human gestation, maternal bone turnover increases, as reflected by molecules involved in bone metabolism, such as vitamin D, osteocalcin, sclerostin, sRANKL, and osteoprotegerin; however, recent studies support their emerging role in endocrine functions and glucose homeostasis regulation. Herein, we sought to systematically review current knowledge on the effects of aforementioned maternal bone biomarkers during pregnancy on fetal intrauterine growth and metabolism, neonatal anthropometric measures at birth, as well as on future endocrine and metabolic wellbeing of the offspring. A growing body of literature converges on the view that maternal bone turnover is likely implicated in fetal growth, and at least to some extent, in neonatal and childhood body composition and metabolic wellbeing. Maternal sclerostin and sRANKL are positively linked with fetal abdominal circumference and subcutaneous fat deposition, contributing to greater birthweights. Vitamin D deficiency correlates with lower birthweights, while research is still needed on intrauterine fetal metabolism, as well as on vitamin D dosing supplementation during pregnancy, to diminish the risks of low birthweight or SGA neonates in high-risk populations. [ABSTRACT FROM AUTHOR]

Highlights from the article: Out of the frame: Søren Riis: Unframing Martin Heidegger's understanding of technology: on the essential connection between technology, art, and history. In the first part of the book, Riis explains why Heidegger thought that the essence of technology is not a "technological problem". Heidegger spoke about the essence of technology, but he did not intend to develop a "philosophy of technology".

The article reviews the book "Black City," by Elizabeth Richards.

The article reviews the book "Every Day" by David Levithan.

The article reviews the book "Dead to You," by Lisa McMann.

Reviews the book `On the Move: How and Why Animals Travel in Groups,' edited by S. Boinski and P.A. Garber.

The article reviews the book "Beta," by Rachel Cohn.

The article reviews the book "Enshadowed" by Kelly Creagh, part of the Nevermore book series.

A review of the book "Mario Diacono," by Mario Diacono is presented.

A review of the book "The Normal Kid," by Elizabeth Holmes is presented.

A review of the book "Invisible Sun," by David Macinnis Gill is presented.

The article reviews the book "The Jade Notebook," by Laura Resau.

Introduction. Intracranial epidermoid cysts are the most frequent congenital intracranial lesion. They rare and benign tumors that can present in different clinical situations depending on location and extension of the disease. Diagnosis is obtained with radiological imaging with RM and non-enhanced TC as elective investigating methods. Elective treatment is surgery, based on total/subtotal excision sparring healthy neurovascular structures, considering the benign nature of this lesion. Case Report. In this study we present the case of a 79-year-old woman affected by recidivist epidermal cyst of the posterior fossa. Clinical presentation was characterized by positional subjective vertigo, intense headache localized in the right part of the head increased by Valsalva maneuver and retroarticular subcutaneous swelling. Radiological investigation found a giant epidemoid cyst of the posterior fossa (8,4 x 4,8 x 5,8 cm), treated with surgery. In the postoperative, the patient was fine and no neurological deficit has been encounterd. REVIEW. In this study, we present a review of the literature regarding giant epidermoid cysts of posterior fossa. Only 11 cases were reported before ours, which actually is one of the largest ever described. [ABSTRACT FROM AUTHOR]