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The article reports on cases of in-frame deletion mutation in juxtamembrane domain (JMD) of the FLT3 (Fms-like tyrosine kinase 3). It states that cases include patients with easy bruisability and petechiae and hyperdiploid B cell-acute lymphoblastic leukemia and bone marrow showed increase count in myeloblast cells. It mentions that in one patient the deletion mutation was missing upon relapse, suggesting that mutation may not be driver mutation having different genetic backgrounds.