1. The golden anniversary of the thymus.
- Author
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Miller, Jacques F. A. P.
- Subjects
- *
THYMUS , *LABORATORY mice , *ANIMAL models of leukemia , *T cells , *IMMUNITY , *LYMPHOCYTES , *THYMUS surgery , *ANIMAL populations , *ANIMALS , *BIOLOGICAL models , *CELL differentiation , *CELL receptors , *CELL motility , *THORACIC surgery , *LEUKEMIA , *MEDICAL research , *MICE , *TIME - Abstract
The immunological function of the thymus was first documented 50 years ago by using neonatally thymectomized mice, while studying its role in virus-induced leukaemia. Since then, an enormous wealth of reports has helped to define the importance of this primary lymphoid organ. In this article, I summarize the key advances that have led to our current knowledge of the functions of the thymus and its T cells in immunity. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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