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Your search keyword '"CLUSTER randomized controlled trials"' showing total 3 results
Start Over Descriptor "CLUSTER randomized controlled trials" Publication Type Reviews
3 results on '"CLUSTER randomized controlled trials"'

1. System-integrated technology-enabled model of care (SINEMA) to improve the health of stroke patients in rural China: Statistical analysis plan for a cluster-randomized controlled trial.

Author

Gong, Enying, Yan, Lijing L, McCormack, Kara, Gallis, John A, Bettger, Janet Prvu, and Turner, Elizabeth L

Subjects
*CLUSTER randomized controlled trials, *STATISTICS, *STROKE patients, *CRIME & the press, *DATA analysis
Abstract

Background: The system-integrated technology-enabled model of care (SINEMA) trial aimed to evaluate the effectiveness of a community-based multi-component intervention for secondary prevention of stroke in rural China. Objective: To present the detailed statistical analysis plan for the trial prior to database locking and data analysis. Methods: The detailed analysis plan outlines primary and secondary outcome measures, describes the over-arching data analysis principles to be adopted as well as more detailed descriptions of specific analytical approaches for effectiveness analyses, as well strategies to handle missing outcome data. Discussion: Publication of the statistical analysis plan increases the transparency of the data analysis procedure and reduces potential bias in trial reporting. Trial registration: The trial was registered with clinicaltrials.gov (NCT03185858). [ABSTRACT FROM AUTHOR]

Published
2020
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2. A Review of Causality in a Social World: Moderation, Mediation, and Spill-Over.

Author

Dong, Nianbo and Kelcey, Benjamin M.

Subjects
MEDIATION (Statistics), MEDIATION, FACTORIAL experiment designs, SOCIAL sciences education, MODERATION, TREATMENT effectiveness, CLUSTER randomized controlled trials
Abstract

Chapter 5 reviews the existing design and analytic methods for evaluating multivalued treatments and introduces MMWS for evaluating multivalued treatments. In addition, the book applies a set of the propensity score-based nonparametric weighting methods (e.g., MMWS, RMPW) for estimating these causal effects. This conventional moderated treatment effect definition is not necessarily causal in nature - although the average treatment effect estimates for the subgroups are unbiased, the treatment effect difference between two subgroups could be due to variables other than the hypothesized moderator variable ([2]). [Extracted from the article]

Published
2020
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3. Textbook of clinical trials in oncology: a statistical perspective: by Susan Halabi and Stefan Michiels, CRC Press, May 2019, 626 pp. ISBN 9781138083776, Price: hardback $159.95.

Author

Jin, Man and Fang, Yixin

Subjects
*CLINICAL trials, *ONCOLOGY, *CLUSTER randomized controlled trials, *TEXTBOOKS
Abstract

This highly anticipated book focuses on clinical trials in oncology, ranging from early, middle, and late phase trials to advanced topics such as precision medicine and immunotherapy. Phase IV trials, also known as post-marketing surveillance trials, include the safety surveillance and ongoing technical support of a drug after it receives market authorization from regulatory authorities. For Phase II clinical trials, Chapter 4 overviews traditional designs, Chapter 5 discusses immunotherapy trials, and Chapter 6 introduces adaptive designs. [Extracted from the article]

Published
2020
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