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Acid-sensing ion channels (ASICs) are cation-permeable channels that in the periphery are primarily expressed in sensory neurons that innervate tissues and organs. Soon after the cloning of the ASIC subunits, almost 20 yr ago, investigators began to use genetically modified mice to assess the role of these channels in physiological processes. These studies provide critical insights about the participation of ASICs in sensory processes, including mechanotransduction, chemoreception, and nociception. Here, we provide an extensive assessment of these findings and discuss the current gaps in knowledge with regard to the functions of ASICs in the peripheral nervous system. [ABSTRACT FROM AUTHOR]

The article reviews the book "Die Schweiz im Europäisierungsprozess: Wirtschafts- und gesell- schaftspolitische Konzepte am Beispie der Arbeitsmigration-, Agrar- und Wissenschaftspolitik, 1947--1974," by Thomas Gees.

Reviews several books. "De Gaulle's Republic," by Philip M. Williams and Martin Harrison, "The de Gaulle Republic: Quest for Unity," by Roy C. Macridis and Bernard E. Brown, "The Fifth French Republic," by Dorothy Pickles; "The Fifth Republic: France's New Political System," by Nicholas Wahl; "The Correspondant and the Founding of the Third French Republic," by M. Caroline Ann Gimpl.

The article reviews the book "A Savage War of Peace: Algeria 1954-1962," by Alistair Horne.