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A recent trial has found that the weight-loss injection Wegovy, made up of the drug semaglutide, can reduce the risk of heart attacks and strokes. This result is significant because it suggests that weight-loss injections could become a normal part of healthcare, similar to taking cholesterol-lowering statins. Semaglutide is a once-weekly injection that mimics the actions of a hormone called GLP-1, which helps control blood sugar and suppresses appetite. The cost and availability of Wegovy have been barriers to access, but with evidence of its effectiveness in preventing medical conditions like heart disease, insurers may expand coverage. Additionally, the approval of another weight-loss injection called tirzepatide may increase the supply of these drugs and potentially lower their cost in the future. Overall, this trial highlights the importance of treating obesity as a medical issue rather than just a cosmetic concern. [Extracted from the article]

Minute plastic particles may enter the human body through the intestinal tract or the air. An international research group examined whether such particles occur in arteriosclerotic vascular lesions. In their study on persons undergoing carotid artery sur - gery, they found plastic particles in 150 out of 257 (58.3 %) ex - cised lesions. Patients with plastic in their lesions had a 4.5-fold higher risk of developing negative cardiovascular events in the following 33 months compared to plastic-negative patients. [ABSTRACT FROM AUTHOR]

The article discusses the Lotus Elan M100, a car that was introduced in the United States in 1991. The author describes the car as unique and unconventional, with a design that differed greatly from the original Lotus Elan. Despite its appealing appearance, the Lotus Elan M100 faced challenges in the market due to the lack of financial resources and limited availability of Lotus dealerships. The article also mentions the car's features and performance, highlighting its lightweight construction and balanced handling. However, the Lotus Elan M100 ultimately struggled to gain popularity in the US, as it did not fit the stereotype of a high-performance track car typically associated with the Lotus brand. [Extracted from the article]

The article is about ischemic heart disease and its different clinical manifestations, such as angina pectoris, acute myocardial infarction, and unstable angina. It mentions cardiovascular risk factors and treatment to modify the risk of the disease. Diagnostic tests, pharmacological management, and recommendations for follow-up and secondary prevention of patients are also discussed. Additionally, it talks about the management of anxiety and depression, as well as cardiac rehabilitation programs. It concludes that Nordic walking is the training modality that most significantly improved exercise capacity and quality of life in patients with ischemic heart disease. [Extracted from the article]

The article reviews the music video "Sexual" by SHAB.

The C8 team could have easily installed a pushrod V-8 with a blower on top, but a supercharged engine doesn't have the character of a flat-plane-crank V-8. CORVETTE EXECUTIVE CHIEF ENGINEER TADGE JUECHTER IS CANDID about the real reason why America's sports car got a mid-engine layout: "When we went mid-engine, the justification for it wasn't the standard car." Exactly how much horsepower Chevy has extracted from its all-new double-overhead-cam (DOHC) 5.5-liter V-8 will be revealed when the engine passes its certification. [Extracted from the article]

The article offers information on retinal ischemic perivascular lesions (RIPLs), detected via OCT, which are indicative of certain systemic cardiovascular conditions, diabetes with or without diabetic retinopathy, and hypertension.

Having had a career in nursing since the mid-1980s and the role of a senior lecturer for 20 years, I thought I would recognise a heart attack if I saw one. Until it happened to me. [ABSTRACT FROM AUTHOR]

"Where the Forest Meets the River" by Shannon Bowring is a novel that explores the lives of the residents of Dalton, Maine, as they navigate grief and interpersonal conflicts. Set in 1995, the story follows Nate, a widower who has left his job to raise his daughter, Sophie, and his mother-in-law, Annette, who struggles with addiction. The novel also delves into the lives of other characters, such as Greg, a bisexual college student, and Rose, a single mother. The book effectively portrays the impact of suicide on the characters' lives and challenges the notion that suicide is just a fleeting moment. [Extracted from the article]

"Showmance" is a sparkling debut novel by playwright Chad Beguelin. The story follows Broadway musical writer Noah Adams as he returns home to rural Plainview, Illinois, after his father's heart attack. Noah's adaptation of King Lear has failed, and he is feeling down. However, things take a turn when he discovers that his high school nemesis, Luke Carter, is now working for his family. When Noah is asked to direct a production of his failed musical for the local community theater, he reluctantly agrees. As he works with the locals, he realizes that their changes have improved his show and that he may have misjudged Luke. The two men fall in love, and Noah is torn between staying in his hometown or returning to New York. This charming and witty romance is filled with musical theater references and explores themes of redemption and second chances. [Extracted from the article]

Yasmin Angoe's novel "Not What She Seems" follows Jacinda Brodie, a research assistant who returns to her Southern hometown to care for her sick grandfather. After being passed over for a fellowship, Jac discovers that her boss, bestselling author Conrad Meckleson, sabotaged her chances due to their past affair. To make matters worse, Jac learns that Conrad plans to write a true crime book about the death of her father, who fell off a cliff six years ago, making Jac a suspect. As Jac investigates, she becomes suspicious of Faye Arden, a mysterious entrepreneur who recently renovated Moor Manor. Angoe's book features well-developed characters and unexpected plot twists. [Extracted from the article]

"Shaking in the Forest: Finding Light in the Darkness" is a memoir by Lori R. Hodges, a paramedic and firefighter. The book delves into Hodges' experiences with trauma and chaos, and how she finds hope and light in the midst of darkness. She shares stories from her childhood, including growing up with an abusive father, as well as her near-death experiences and her work as a first responder. Through humor, honesty, and self-reflection, Hodges explores the impact of trauma and the importance of finding beauty in the world. The memoir offers a message of hope and resilience, emphasizing the choice to hold onto hope even in the face of adversity. [Extracted from the article]

In "By Evening's Light," the final book in the Amish Memories series by Leslie Gould, the protagonist, Treva Zimmerman, visits her Amish grandparents' farm in Lancaster, Pennsylvania, after ending a relationship. However, her plans to start fresh in Alaska are put on hold when her great-great-aunt Rosene suffers a heart attack and Treva stays to care for her. As they spend time together, Rosene shares her difficult upbringing in Nazi Germany and her lost love. Treva, despite her own responsibilities, begins to investigate what happened to Rosene's long-lost love. The book explores themes of loss, duty, and the impact of the past on the present. [Extracted from the article]

"The Last Line" by Scott Lyerly is a promising debut novel that follows Ellie Marlowe, the owner of a community theater in Massachusetts, as she investigates the death of one of her actors. Despite the initial belief that the actor died of a heart attack, Ellie suspects foul play and teams up with her friend, local police chief Bill Starlin, to uncover the truth. However, the author's withholding of crucial information and repetition of plot points detract from the potential of the story. Overall, "The Last Line" has the potential to be a captivating read, but falls short in execution. [Extracted from the article]

In "The Widow's Guide to Dead Bastards: A Memoir," author Jessica Waite shares her experience of her husband's death and the shocking secrets she discovered after his passing. The memoir explores their 20-year marriage, which was marked by both good times and challenges due to frequent travel for work and her husband's bipolar disorder. After his death, Waite uncovered his extensive collection of digital pornography, his hidden cannabis use, multiple affairs, and financial deception. Through writing and grief support groups, she eventually finds a fragile acceptance of her husband's flawed humanity. Waite's compassionate and witty approach offers a thought-provoking exploration of loss and forgiveness. [Extracted from the article]

The article recounts the tragic death of 29-year-old farmer Bryce Driver from a heart attack, leaving behind his wife and newborn twins, with the community rallying around them in support.

The article offers information on the safety and liability climate of the U.S. Fire Service, as of September 2021. Topics covered include the decline in line-of-duty deaths (LODDs), the breakdown of fatalities based on the U.S. Fire Administration data and the common causes of firefighter LODDs. It also discusses the real cause of LODDs and the cost of addressing firefighting injuries and of efforts to prevent them.

The article discusses role of Chief to have ability of visionary leadership. Topics discussed include chief's intention to progress and improve the organization for the stakeholders; role of visionary leader to build a road map and communicate it effectively to the people who implement the essential components; and need to have a command structure that allows for technical decisions and actions to be made at lower leadership levels.

"Val Vega: Secret Ambassador of Earth" by Ben Francisco is a thrilling young adult novel set in a world of interstellar politics and alien intrigue. After the death of her uncle, Val Vega discovers that he was Earth's ambassador to the interstellar council of planets and that he may have been murdered. As Val steps into her uncle's role, she must navigate the complex world of interstellar negotiations and uncover the traitor among her uncle's alien coworkers. With diverse characters and a blend of politics, space negotiations, and a murder mystery, this fast-paced novel delivers an important message about resolving differences without violence. Recommended for fans of Marissa Meyer's "Cress" and Jina S. Bazzar's "Imperial Stardust." [Extracted from the article]

In Tongues is a fiction novel by Thomas Grattan that follows the story of a young gay narrator named Gordon who moves to New York City in the summer of 2001. He begins working for an older gay couple, Philip and Nicola, and becomes entangled in a series of reckless actions, including kissing Nicola and throwing a party in their home. Gordon also develops a relationship with Pavel, a painter, and navigates his strained relationship with his disapproving father. The novel explores themes of self-destructive tendencies and the complexities of friendship. [Extracted from the article]

"One Icy Night: 30th Anniversary of the '94 Delta Ice Storm Edition" by W.A. Pepper is a heart-stopping thriller set during a history-making ice storm in the Mississippi Delta. The protagonist, Ruth "Rook" Kellum, finds herself running for her life after making a series of bad choices. The story is fast-paced and suspenseful, with every character Rook encounters being suspicious in some way. The author, drawing from his own experiences during the real-life Delta Ice Storm in 1994, effectively portrays the chilling sense of terror caused by the storm. This book is recommended for fans of Last Night by Luanne Rice and Rock Paper Scissors by Alice Feeney. [Extracted from the article]

This article describes a programme of research focused on supporting people with heart disease. The development of this programme, which continues to evolve, arose from my clinical experience in the early 1980s when I was a senior nurse in a coronary care unit. [ABSTRACT FROM AUTHOR]

Le Corbusier occasionally stayed in Gray's villa and built his rustic log cabin home nearby in 1951, called Cabanon (he died there while swimming in the sea in 1965, of a reported heart attack). AFTER ALMOST seven years of meticulous restoration work, Eileen Gray's Villa E-1027 has been reopened to the public on its rocky waterfront site in Roquebrune-Cap-Martin, in southern France. Eileen Gray's Villa E-1027 Reopens to the Public. [Extracted from the article]

Helping patients select and properly use nonprescription sleep aids when appropriate and directing patients to seek further medical evaluation for chronic insomnia. Results from several studies indicate that insomnia is associated with a decline in cognitive function and increased cardiovascular and metabolic risk factors.45 Many patients who struggle with insomnia initially try nonprescription sleep aids. [Extracted from the article]

The article deals with a 2019 report on awareness of heart attack symptoms and response among U.S. adults in 2008, 2014, and 2017. National Health Interview Survey data analyzed by the Centers for Disease Control and Prevention (CDC) were used in the report. The report cites a significant increase in knowledge of five common signs and symptoms of a heart attack, as well as the appropriate emergency response.

The article informs about that retinal vein occlusion (RVO) is linked to cardiovascular risk factors and may have predictive value for vascular events and mortality. Topic include In a study involving 45,303 RVO patients and a control group, researchers found increased risks of death, stroke, and myocardial infarction after RVO, particularly for patients with central RVO, while deep vein thrombosis and pulmonary embolism risks were relatively low.

Otalgia is ear pain and can have different causes. In children, the most common causes are infections of the external and middle ear, while in adults they are usually dental problems, temporomandibular dysfunction, pharyngitis, and cervicoarthrosis. However, persistent secondary otalgia can be symptoms of serious diseases such as temporal arteritis, head and neck tumors, and acute myocardial infarction. Acute otitis media is one of the most frequent reasons for consultation in pediatrics, and temporal arteritis is more common in people over 50 years old. Clinical tests can be performed to diagnose these diseases, such as otoscopy and palpation of the temporal artery. [Extracted from the article]

Acute pericarditis is an exceptional cause of chest pain in Primary Care. The majority of cases are idiopathic or viral, while the rest are caused by bacterial infections, tuberculosis, or other processes. The diagnosis of acute pericarditis is based on the presence of pleuritic pain, pericardial friction rub, alterations in the electrocardiogram (ECG), and pericardial effusion. Physical examination and ECG are useful in the diagnosis, but up to 60% of cases may have a normal echocardiogram due to the small amount of effusion. The differential diagnosis between acute pericarditis, acute myocardial infarction, and early repolarization can be made through the ECG. [Extracted from the article]

ENDORSEMENT IT'S UNLIKELY THAT anyone hoping to shed a few pounds this New Year isconsidering eating more health salad. No one goesto a deli for their health, after all, let alone just to eat health salad. Like delis themselves, health salads are on the wane. [Extracted from the article]

MacDonald's dream became a reality in May, and he has already put more than 1300 miles on the car. The plate on Alex MacDonald's homebuilt Stalker reads "ASIL Z." MacDonald is General Motors' Corvette and Camaro vehicle-performance manager, which means, among other jobs, he's in charge of making sure the Corvette chassis sings to you [see "Heart Attack", page 24]. [Extracted from the article]

Acute coronary syndrome is a serious condition that requires urgent assessment and management. This article outlines the nature of the condition, and discusses its underlying pathophysiology. It discusses three types of acute coronary syndrome: unstable angina, ST elevation myocardial infarction and non-ST elevation myocardial infarction. Research and guidelines are used to guide the reader through approaches to initial nursing assessment and the immediate management of patients with suspected acute coronary syndrome. [ABSTRACT FROM AUTHOR]

The article presents a study published in Ophthalmology Science has identified novel genetic loci associated with retinal vessel tortuosity and their links to ocular and cardiometabolic diseases, providing a significant advancement in understanding molecular mechanisms for developing better tools for diagnosis and treatment.

VA/DoD clinical practice guideline for the diagnosis and treat-ment of low back pain. Low back pain is a common musculoskeletal condition globally, as well as one of the top causes of limitations to physical activity. [Extracted from the article]

The article focuses on the benefits of krill oil derived omega-3 free fatty acid . Topics includes the krill oil formulation containing a mixture of free omega-3 fatty acids and phospholipid acid esters, ways in which the oil produces a significant reduction in triglycerides in two randomised placebo-controlled trials.

The article discusses the supplementation of Vitamin D for a period of 5-years failed to produce an effect on either cardiovascular events or cancer incidence which includes Vitamin D has a universal action in humans as witnessed by the large number of vitamin D receptors in tissues throughout the body.