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Laser technologies improved after the understanding of the Chirped Pulse Amplification (CPA) which allows energetic laser beams to be compressed to tens of femtosecond (fs) pulse durations and focused to few $\mu$m. Protons of tens of MeV can be accelerated using for instance the Target Normal Sheath Acceleration (TNSA) method and focused on secondary targets. In such conditions, nuclear reactions can occur and radioisotopes relevant for medical purposes be produced. High repetition lasers can be used to produce enough isotopes for medical applications. This route is competitive to conventional methods mostly based on accelerators. In this paper we study the production of $^{67}$Cu, $^{63}$Zn, $^{18}$F and $^{11}$C currently used in positron emission tomography (PET) and other applications. At the same time, we study the reaction $^{10}$B(p,$\alpha$)$^{7}$Be and $^{70}$Zn(p,4n)$^{67}$Ga to put further constraints to the proton distributions at different angles and to the reaction $^{11}$B(p,$\alpha$)$^{8}$Be relevant for energy production. The experiment was performed at the 1 petawatt (PW) laser facility at Vega III located in Salamanca-Spain. Angular distributions of radioisotopes in the forward (with respect to the laser direction) and backward directions were measured using a High Purity Germanium Detector (HPGE). Our results are reasonably reproduced by the numerical estimates following the approach of Kimura et al. (NIMA637(2011)167)

The goal of this reply is to draw attention of the readers that the major problems rose in the short Comment authored by A.M. Mukhamedzhanov, X. Tang and D.Y. Pang (arXiv:1806.05921) are totally groundless., Comment: 4 pages, 2 figures

The decay path of the Hoyle state in $^{12}$C ($E_x=7.654\textrm{MeV}$) has been studied with the $^{14}\textrm{N}(\textrm{d},\alpha_2)^{12}\textrm{C}(7.654)$ reaction induced at $10.5\textrm{MeV}$. High resolution invariant mass spectroscopy techniques have allowed to unambiguously disentangle direct and sequential decays of the state passing through the ground state of $^{8}$Be. Thanks to the almost total absence of background and the attained resolution, a fully sequential decay contribution to the width of the state has been observed. The direct decay width is negligible, with an upper limit of $0.043\%$ ($95\%$ C.L.). The precision of this result is about a factor $5$ higher than previous studies. This has significant implications on nuclear structure, as it provides constraints to $3$-$\alpha$ cluster model calculations, where higher precision limits are needed.

Measurement of nuclear cross sections at astrophysical energies involving unstable species is one of the most challenging tasks in experimental nuclear physics. The use of indirect methods is often unavoidable in this scenario. In this paper the Trojan Horse Method is applied for the first time to a radioactive ion beam induced reaction studying the $^{18}$F($p,{\alpha}$)$^{15}$O process at low energies relevant to astrophysics via the three body reaction $^{2}$H($^{18}$F,${\alpha}^{15}$O)n. The knowledge of the $^{18}$F($p, {\alpha}$)$^{15}$O reaction rate is crucial to understand the nova explosion phenomena. The cross section of this reaction is characterized by the presence of several resonances in $^{19}$Ne and possibly interference effects among them. The results reported in Literature are not satisfactory and new investigations of the $^{18}$F($p,{\alpha}$)$^{15}$O reaction cross section will be useful. In the present work the spin-parity assignments of relevant levels have been discussed and the astrophysical S-factor has been extracted considering also interference effects, Comment: 7 pages, 4 figures

The $^{10}$B(p,$\alpha_0$)$^7$Be bare nucleus astrophysical S(E)-factor has been measured for the first time at energies from about 100 keV down to about 5 keV by means of the Trojan Horse Method (THM). In this energy region, the S(E)-factor is strongly dominated by the 8.699 MeV $^{11}$C level (J$^{\pi}$=$\frac{5}{2}$$^+$), producing an s-wave resonance centered at about 10 keV in the entrance channel. Up to now, only the high energy tail of this resonant has been measured, while the low-energy trend is extrapolated from the available direct data. The THM has been applied to the quasi-free $^2$H($^{10}$B,$\alpha_0$$^7$Be)n reaction induced at a boron-beam energy of 24.5 MeV. An accurate analysis brings to the determination of the $^{10}$B(p,$\alpha_0$)$^7$Be S(E)-factor and of the corresponding electron screening potential $U_e$, thus giving for the first time an independent evaluation of it., Comment: Authors thank the (anonymous) referee for detailed comments and suggestions. The paper is already submitted to Physical Review C

The reaction $^{17}$O($n,\alpha$)$^{14}$C was studied at energies from $E_{cm}=0$ to $E_{cm}=350$ keV using the quasi-free deuteron break-up in the three body reaction $^{17}$O$+d \rightarrow \alpha+ ^{14}$C$+p$, extending the Trojan Horse indirect method (THM) to neutron-induced reactions. It is found that the $^{18}$O excited state at $E^*=8.125 \pm 0.002$ MeV observed in THM experiments is absent in the direct measurement because of its high centrifugal barrier. The angular distributions of the populated resonances have been measured for the first time. The results unambiguously indicate the ability of the THM to overcome the centrifugal barrier suppression effect and to pick out the contribution of the bare nuclear interaction., Comment: Accepted by PRC as Rapid Communication

The Trojan Horse Method was applied for the first time to a Radioactive Ion Beam induced reaction to study the reaction $^{18}$F(p,$\alpha$)$^{15}$O via the three body reaction $^{18}$F(d,$\alpha$ $^{15}$O)n at the low energies relevant for astrophysics. The abundance of $^{18}$F in Nova explosions is an important issue for the understanding of this astrophysical phenomenon. For this reason it is necessary to study the nuclear reactions that produce or destroy $^{18}$F in Novae. $^{18}$F(p,$\alpha$)$^{15}$O is one of the main $^{18}$F destruction channels. Preliminary results are presented in this paper., Comment: Talk given by Marisa Gulino at the 11th International Conference on Nucleus-Nucleus Collisions (NN2012), San Antonio, Texas, USA, May 27-June 1, 2012. To appear in the NN2012 Proceedings in Journal of Physics: Conference Series (JPCS)

Multi-center (molecular) structures can play an important role in light nuclei. The highly deformed rotational band in 10Be with band head at 6.179 MeV has been observed recently and suggested to have an exotic alpha:2n:alpha configuration. A search for states with alpha:pn:alpha two-center molecular configurations in 10B that are analogous to the states with alpha:2n:alpha structure in 10Be has been performed. The T=1 isobaric analog states in 10B were studied in the excitation energy range of E=8.7-12.1 MeV using the reaction 1H(9Be,alpha)6Li*(T=1, 0+, 3.56 MeV). An R-matrix analysis was used to extract parameters for the states observed in the (p,alpha) excitation function. Five T=1 states in 10B have been identified. The known 2+ and 3- states at 8.9 MeV have been observed and their partial widths have been measured. The spin-parities and partial widths for three higher lying states were determined. Our data support theoretical predictions that the 2+ state at 8.9 MeV (isobaric analog of the 7.54 MeV state in 10Be) is a highly clustered state and can be identified as a member of the alpha:np:alpha rotational band. The next member of this band, the 4+ state, has not been found. A very broad 0+ state at 11 MeV that corresponds to pure alpha+6Li(0+,T=1) configuration is suggested and it might be related to similar structures found in 12C, 18O and 20Ne., Comment: 10 pages, 10 figures, accepted in Physical Review C

The 18O(p,alpha)15N reaction rate has been extracted by means of the Trojan-Horse method. For the first time the contribution of the 20-keV peak has been directly evaluated, giving a value about 35% larger than previously estimated. The present approach has allowed to improve the accuracy of a factor 8.5, as it is based on the measured strength instead of educated guesses or spectroscopic measurements. The contribution of the 90-keV resonance has been determined as well, which turned out to be of negligible importance to astrophysics., Comment: 6 pages, 4 figures, 1 table. Torino workshop 2008

The $^{18}{\rm O}(p,\alpha)^{15}{\rm N}$ reaction is of primary importance in several astrophysical scenarios, including fluorine nucleosynthesis inside AGB stars as well as oxygen and nitrogen isotopic ratios in meteorite grains. Thus the indirect measurement of the low energy region of the $^{18}{\rm O}(p,\alpha)^{15}{\rm N}$ reaction has been performed to reduce the nuclear uncertainty on theoretical predictions. In particular the strength of the 20 and 90 keV resonances have been deduced and the change in the reaction rate evaluated., Comment: 4 pages, 4 figures, submitted to PRL