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The article presents information about Quadramet, a drug produced by Cytogen Corp. It has been found in a study that Cytogen Inc.'s Quadramet plus Eli Lilly & Co.'s Gemzar demonstrated positive clinical responses in advanced osteosarcoma. Currently, Quadramet is prescribed for the relief of pain in patients with confirmed osteoblastic bone lesions that enhance on radionuclide bone scan. But it is under an investigation for numerous other indications, both on its own and in combination with radiosensitizing chemotherapeutic agents.