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During the energy transition, the significance of collaborative management among institutions is rising, confronting challenges posed by data privacy concerns. Prevailing research on distributed approaches, as an alternative to centralized management, often lacks numerical convergence guarantees or is limited to single-machine numerical simulation. To address this, we present a distributed approach for solving AC Optimal Power Flow (OPF) problems within a geographically distributed environment. This involves integrating the energy system Co-Simulation (eCoSim) module in the eASiMOV framework with the convergence-guaranteed distributed optimization algorithm, i.e., the Augmented Lagrangian based Alternating Direction Inexact Newton method (ALADIN). Comprehensive evaluations across multiple system scenarios reveal a marginal performance slowdown compared to the centralized approach and the distributed approach executed on single machines -- a justified trade-off for enhanced data privacy. This investigation serves as empirical validation of the successful execution of distributed AC OPF within a geographically distributed environment, highlighting potential directions for future research.

Protein function prediction may be framed as predicting subgraphs (with certain closure properties) of a directed acyclic graph describing the hierarchy of protein functions. Graph neural networks (GNNs), with their built-in inductive bias for relational data, are hence naturally suited for this task. However, in contrast with most GNN applications, the graph is not related to the input, but to the label space. Accordingly, we propose Tail-GNNs, neural networks which naturally compose with the output space of any neural network for multi-task prediction, to provide relationally-reinforced labels. For protein function prediction, we combine a Tail-GNN with a dilated convolutional network which learns representations of the protein sequence, making significant improvement in F_1 score and demonstrating the ability of Tail-GNNs to learn useful representations of labels and exploit them in real-world problem solving.