The formation and evolution of the Martian surface, and ultimately the fate of its various volcanic regions, are revealed in the chemistry of Martian meteorites, and the mineralogy of the crust. The interpretation of the chemistry from remote sensing instrumentation from orbiters and landers/rovers has been strongly influenced by our knowledge of geochemical processes on Earth, the Moon, and other asteroidal, rocky bodies [1]. The composition, and thus evolution, of the Martian crust has been resultant from SNC (shergottite –nakhlite –chassignite) meteorites, which are the igneous counterpart of rocks of Martian origin [2, 3, 4]. These meteorites are chemically similar to terrestrial basalts and cumulates, with the exception of higher concentrations of iron and other volatile elements (i.e., phosphorous, chlorine, chalcophile) [5]. From Tuff et al. [2], most Martian meteorites have relatively young crystallization ages ranging from 1.4 billion years to 180 million years ago [6]. These are considered to be derived from young, usually lightly-cratered volcanic regions, such as the Tharsis volcanic region [6, 7]. Though mainly basaltic in composition, surface rocks are richer in nickel and sulfur with lower manganese/iron ratios than Martian meteorites [2], which can be explained by the differences in oxygen fugacity during melting of the sulfur-rich mantle [2, 8]. From this difference, Martian meteorites are tied to surface rocks through an early (3.7 billion years ago) oxidation of the uppermost mantle, producing the more recent volcanic rocks [2]. The variety of compositions from basaltic, olivine volcanic rocks through pyroxene-cumulate nakhlites and peridotite chassignites, enable the hypothetical reconstructions of the silicic evolution of Mars similar to techniques used on Earth [2, 5, 9]. In this chapter, we will explore the basic Martian composition of the crust and mantle in regards to volcanic regions, the crustal components of the North-South dichotomy, and more detail of the SNC meteorites in relation to the evolution of the mantle for volcanism.