1. Antibacterial and Anti- Biofilm Properties of Silver Nanoparticles Synthesized from Sugarcane Bagasse Hydrolysates.
- Author
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Aita, Giovanna M. and Young Hwan Moon
- Subjects
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SILVER nanoparticles , *BAGASSE , *METAL nanoparticles , *SUGARCANE , *BIOFILMS - Abstract
Sugarcane bagasse is a rich source of bioactive compounds (e.g., phenolics) known to have antimicrobial, antioxidant, anticancer, and anti-inflammatory properties. These bioactive molecules can be used in the green synthesis of metal nanoparticles. Metal nanoparticles have gathered attention because of their novel physico-chemical properties and potential biological applications (e.g., biocides, pesticides, plant biostimulants). Silver nanoparticles are of particular interest as they can be easy to operate and are cost effective, biocompatible, and their biological activities can be enhanced by surface modifications. In this study, the reducing potential of the phenolic compounds extracted from sugarcane bagasse was investigated for the synthesis of silver nanoparticles without the external addition of reducing agents. The reddish color formation and peak appearance at 420 nm were indications of the successful synthesis of the silver nanoparticles. The synthesized nanoparticles were further characterized by microscopy techniques indicating nanoparticles of spherical shape and with particle sizes averaging -15 nm. The antimicrobial activity of the synthesized nanoparticles was evaluated against several microbial species, some of which had been isolated from cane juice. The synthesized nanoparticles showed a biocidal effect against bacteria which was further confirmed by microscopy techniques. It appears that the nanoparticles are interacting with the cell surface of microorganisms, penetrating the cell and also causing the disruption of intracellular organelles. These nanoparticles can also reduce the growth of microbial biofilms. A biofilm is a complex and functional community of microbes encased in a primarily polysaccharide matrix, which act as a barrier to protect microbes against most biocides. [ABSTRACT FROM AUTHOR]
- Published
- 2024