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A study conducted in Qatar between 2013 and 2022 examined the effects of celecoxib, a medication used for allergy testing, on 31 patients. One patient, whose age and sex were not specified, experienced anaphylaxis during the challenge with a single dose of oral celecoxib 200mg. It was noted that the patient had previously experienced anaphylaxis to celecoxib, but the outcome of this incident was not mentioned. [Extracted from the article]

Author InformationAn event is serious (based on the ICH definition) when the patient outcome is:• * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important eventA 29-year-old woman developed capillary leak syndrome during treatment with sorafenib and celecoxib for desmoid tumour of the thigh. [Extracted from the article]

A 13-year-old boy developed gastric outlet obstruction while being treated with celecoxib for relapsed metastatic medulloblastoma. The boy had previously undergone various treatments for his condition, including surgery, radiotherapy, chemotherapy, and immunotherapy. After starting celecoxib-containing metronomic therapy, he experienced symptoms such as heartburn, bloating, vomiting, and weight loss. Further examination revealed severe pyloric stenosis causing the obstruction. The boy underwent balloon dilatation and stenting procedures, which successfully resolved the obstruction. The gastric outlet obstruction was attributed to celecoxib. [Extracted from the article]

On the day 6 of hospitalisation, upper gastrointestinal endoscopy showed massive gastric ulcer of posterior wall of gastric body, which was attributed with celecoxib [ I time to reaction onset not stated i ]. After one month of discharge, endoscopy showed almost complete resolution of the gastric ulcer. B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event A 78-year-old woman developed gastric ulcer during treatment with celecoxib for rib fracture. [Extracted from the article]

In a placebo-controlled, single-blind, prospective study of 116 patients with a positive history of hypersensitivity to NSAIDs, who underwent oral challenge test at the Allergy Clinic of the Clinical Hospital of Ribeirao Preto Medical School, Brazil between October 2010 and July 2014, a patient [ I age and sex not stated i ] was described who developed anaphylaxis following administration of celecoxib. The patient underwent an oral challenge test with celecoxib and developed anaphylaxis [ I dose, duration of treatment to reaction onset and outcome not stated i ]. B Author comment: b I "One patient presented with anaphylaxis during [oral challenge test] using Celecoxib." i. [Extracted from the article]

An abstract of the article "Role of cyclooxygenase inhibitors in aquagenic syringeal acrokeratoderma" by A. Akin Belli and others is presented.

The article presents the case studies of a 71-year-old woman and a 68-year-old man who both developed longlasting and irreversible bilateral vestibular failure after concomitant treatment with penicillins and cyclooxygenase inhibitors.