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The article discusses a study that used single-cell transcriptomic technology to analyze the activity and clustering of cells in psoriasis. Topics include the identification of cell activity associated with inflammation in severe psoriasis, the exploration of systemic impact and comorbidities and the examination of gene activity related to metabolism and lipid levels.

The article discusses research by Shaun Kunisaki and colleagues, reported in the "Journal of Pediatrics" issue on June 22, 2023, on the survival rates of girls with congenital diaphragmatic hernia (CDH). It mentions that the study found that girls with CDH have slightly lower survival rates compared to boys with the condition, even after controlling for markers of disease severity.

The article present two studies presented at the annual research symposium of the Gout, Hyperuricemia and Crystal Associated Disease Network (G-CAN). It suggests that it may not be necessary to delay urate-lowering therapy (ULT) during gout flares, as early initiation of ULT does not affect flare severity, duration or recurrence; heightened risk of peripheral arterial disease (PAD) in patients with gout and emphasizing the underrecognized risk & the importance of assessing PAD in gout patients.

The article discusses research on a scorecard developed to help pediatricians predict peanut allergies among infants with atopic dermatitis. It mentions that the scorecard assesses the severity of atopic dermatitis in infants of various skin tones and correlates it with the risk of peanut allergies, providing pediatricians with a tool to better identify and guide families in preventing peanut allergies.

The article focuses on the influence of sociodemographic characteristics on the severity of systemic lupus erythematosus (SLE) in African American and Hispanic children. Topics include the association between health determinants and disease severity in a Texas city; the greater severity and social hardships experienced by African American children in Mississippi and Alabama; and the prevalence of childhood-onset SLE is greater among Black and Hispanic children.

The article discusses research on improving dengue severity assessments through a new blood test. It references a study published in the "International Journal of Laboratory Hematology" where two teams of doctors from Mumbai and Delhi conducted independent studies and identified the blood parameter immature platelet fraction (IPF) for predicting quick recovery and guide for deciding on a blood transfusion. Conclusions cited how the bone marrow can replace lost platelets faster with higher IPF.

People with severe schizophrenia who have been isolated, withdrawn and considered beyond help can learn to become more active, social and employable by engaging in a type of talk therapy that was invented to treat depression, scientists reported on Monday. These new findings suggest that such patients have far more capability to improve their lives than was previously assumed and, if replicated, could change the way that doctors treat the one million patients for whom the disorder is profoundly limiting. [ABSTRACT FROM AUTHOR]