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A study published in Family Practice News in September 2024 suggests that impaired central sensitivity to thyroid hormone may increase the risk of mortality in patients with chronic kidney disease (CKD) and normal thyroid function. The research, conducted on 1303 euthyroid CKD patients, found that those with higher Thyroid Feedback Quantile-based Index (TFQI) levels had a significantly higher risk of all-cause mortality. The study highlights the potential impact of thyroid hormone resistance on mortality in CKD patients, independent of other risk factors. [Extracted from the article]

The article discusses the potential for newborn genome sequencing to replace traditional newborn screening programs. Dr. David Geneviève, a geneticist, argues that sequencing newborn DNA could allow for the screening of hundreds of childhood genetic diseases. Currently, newborn screening involves taking a blood sample from a newborn's heel, but with genome sequencing, DNA samples could be taken to identify diseases that may develop later in life. Several international trials are already underway to assess the feasibility and benefits of genome sequencing for newborns. However, ethical concerns and the need for societal decision-making are also highlighted. The cost of genome sequencing has significantly decreased in recent years, making it more accessible. Overall, the article emphasizes the potential benefits of newborn genome sequencing in preventing rare diseases. [Extracted from the article]

A study conducted on women with hypothyroidism treated with levothyroxine found no significant cognitive decline during the menopausal transition compared to those without thyroid disease. The research, which included data from the Study of Women's Health Across the Nation, analyzed cognitive function over 13 years in women from diverse ethnic and racial backgrounds. While levothyroxine-treated women initially had higher scores in processing speed and working memory, there was no significant difference in cognitive decline between the groups over time. The study suggested that clinicians should explore other potential causes of cognitive decline in these patients beyond inadequate treatment of hypothyroidism. [Extracted from the article]

A study published in OB-GYN News found that women with hypothyroidism treated with levothyroxine did not experience significant cognitive decline during menopause compared to those without thyroid disease. The research, conducted using data from the Study of Women's Health Across the Nation, included cognitive testing in processing speed, working memory, and episodic memory over a 13-year follow-up period. While levothyroxine-treated women initially had higher scores in processing speed and working memory, there was no significant difference in cognitive decline between the groups over time. The study suggested that clinicians should explore other potential causes of cognitive decline in these patients beyond inadequate treatment of hypothyroidism. [Extracted from the article]

A study published in Internal Medicine News suggests that impaired central sensitivity to thyroid hormone may increase the risk of death in patients with chronic kidney disease (CKD) and normal thyroid function. Researchers analyzed data from 1303 euthyroid CKD patients and found that those with higher Thyroid Feedback Quantile-based Index (TFQI) levels had a significantly higher risk of all-cause mortality. The study highlights the potential impact of thyroid hormone resistance on mortality in CKD patients, independent of other risk factors. [Extracted from the article]

The article focuses on the use of iodized salt in Kazakhstan. The effects of iodine deficiency, including goiters, cretinism, and dwarfism, are discussed. The World Summit for Children, Unicef, and the World Health Organization, among others, demanded the elimination of iodine deficiency. The iodization of salt, according to the article and Ontalap Akhmetov, the president of Aral Tuz, a salt manufacturer, costs very little. Details related to the public response to the iodization of salt in opposing nations are provided. INSETS: An Ounce of Prevention;The Disease.