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Start Over Author "van Marion R" Publication Type Magazines
2 results on '"van Marion R"'

1. IDH1mutations in low-grade astrocytomas predict survival but not response to temozolomide

Author

Dubbink, H J., Taal, W, van Marion, R, Kros, J M., van Heuvel, I, Bromberg, J E., Zonnenberg, B A., Zonnenberg, C B.L., Postma, T J., Gijtenbeek, J M.M., Boogerd, W, Groenendijk, F H., Smitt, P A.E. Sillevis, Dinjens, W N.M., and Bent, M J. van den

Abstract

Mutations in isocitrate dehydrogenase 1 and 2 (IDH1and IDH2) have been implicated in tumorigenesis of gliomas. Patients with high-grade astrocytomas with IDH1or IDH2mutations were reported to have a better survival, but it is unknown if this improved survival also holds for low-grade astrocytoma and whether these mutations predict outcome to specific treatment.

Published
2009
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