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A recent study conducted at Children's Hospital in Cincinnati, Ohio, found that higher caregiver adverse childhood experiences (ACEs) are associated with increased pediatric infection-related healthcare utilization and antibiotic use. The study focused on children aged 0-4 years from two primary care sites serving predominantly non-Hispanic Black, publicly insured populations. Children of caregivers with high ACEs had more outpatient infection-related visits, diagnoses of streptococcal pharyngitis, and prescriptions for oral antibiotics. The research suggests that high caregiver ACEs may impact pediatric infectious diagnoses and healthcare utilization, highlighting the need for further investigation into these associations. [Extracted from the article]

A recent report from Washington University School of Medicine discusses the use of virus-specific T cells (VST) for the treatment of systemic infections in pediatric patients following allogeneic hematopoietic cell and solid organ transplantation. The report highlights the challenges of pharmacological treatment for viral infections and the potential of VST therapy to rapidly restore antiviral immunity. The article provides a practical guide to VST therapy, including manufacturing techniques, donor selection, and treatment indications. The report summarizes the safety and efficacy data of VSTs gathered from clinical trials over the past 30 years and discusses current challenges, limitations, and opportunities for further research and development. [Extracted from the article]

A study conducted by researchers at Indiana University School of Medicine has found that plasma microbial cell-free DNA (mcfDNA) sequencing can be a useful tool for detecting and quantifying pathogens in children with musculoskeletal infections (MSKIs). The study found that mcfDNA sequencing was able to identify a pathogen in a higher percentage of cases compared to traditional culture methods. However, it should be noted that multiple pathogens were frequently detected, highlighting the need for careful interpretation of results. The researchers concluded that mcfDNA sequencing may be particularly beneficial if performed prior to surgery. [Extracted from the article]

London, United Kingdom, Europe, Diagnostics and Screening, Genetics, Health and Medicine, Pediatric Infectious Diseases, Pediatrics, Testing Keywords for this news article include: London, Europe, Testing, Genetics, United Kingdom, Health and Medicine, Diagnostics and Screening, Pediatric Infectious Diseases. Keywords: London; United Kingdom; Europe; Diagnostics and Screening; Genetics; Health and Medicine; Pediatric Infectious Diseases; Pediatrics; Testing EN London United Kingdom Europe Diagnostics and Screening Genetics Health and Medicine Pediatric Infectious Diseases Pediatrics Testing 227 227 1 06/12/23 20230616 NES 230616 2023 JUN 17 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Pediatrics - Pediatric Infectious Diseases is the subject of a report. [Extracted from the article]