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• Bionic hierarchical scaffold fabricated by 3D-printing and surface mineralization. • The obtained biomimetic multi-structured scaffolds facilitate bone regeneration. • Regulation of cell fate in activated PI3K/AKT/mTOR signaling were confirmed. • Hydroxyapatite coating accelerates osseointegration and enhance bone-augmentation. • A two-step method enriches and guides the design of modified bone graft materials. The architecture and surface modifications have been regarded as effective methods to enhance the biological response of biomaterials in bone tissue engineering. The porous architecture of the implantation was essential conditions for bone regeneration. Meanwhile, the design of biomimetic hydroxyapatite (HAp) coating on porous scaffolds was demonstrated to strengthen the bioactivity and stimulate osteogenesis. However, bioactive bio-ceramics such as β-tricalcium phosphate (β-TCP) and calcium silicate (CS) with superior apatite-forming ability were reported to present better osteogenic activity than that of HAp. Hence in this study, 3D-printed interconnected porous bioactive ceramics β-TCP/CS scaffold was fabricated and the biomimetic HAp apatite coating were constructed in situ via hydrothermal reaction, and the effects of HAp apatite layer on the fate of mouse bone mesenchymal stem cells (mBMSCs) and the potential mechanisms were explored. The results indicated that HAp apatite coating enhanced cell proliferation, alkaline phosphatase (ALP) activity, and osteogenic gene expression. Furthermore, PI3K/AKT/mTOR signaling pathway is proved to have an important impact on cellular functions. The present results demonstrated that the key molecules of phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT) and mammalian target of rapamycin (mTOR) were activated after the biomimetic hydroxyapatite coating were constructed on the 3D-printed ceramic scaffolds. Besides, the activated influence on the protein expression of Runx2 and BMP2 could be suppressed after the treatment of inhibitor HY-10358. In vivo studies showed that the constructed HAp coating promoted bone formation and strengthen the bone quality. These results suggest that biomimetic HAp coating constructed on the 3D-printed bioactive composite scaffolds could strengthen the bioactivity and the obtained biomimetic multi-structured scaffolds might be a potential alternative bone graft for bone regeneration. [ABSTRACT FROM AUTHOR]

A recent study conducted in the Russian Federation examined the use of elastic intramedullary nailing in combination with an external fixator for bone lengthening in patients with acquired lower limb shortening. The study included 64 patients and found that the type of nail used and the ratio of nail diameter to medullary canal diameter had a significant effect on the external fixation indices (EFIs) in femoral lengthening. In tibial lengthening, the EFI was influenced by the nail type and the ratio of nail diameter to internal diameter at the osteotomy site. Overall, the study concluded that the combined technique of elastic intramedullary nailing and external fixation provided good results without serious complications in patients with acquired lower limb shortening. [Extracted from the article]

A recent study conducted by the Indian Institute of Technology Roorkee has explored the development of an implant surface with long-lasting antimicrobial properties for orthopedic surgery. The researchers propose a multilayer porous hydroxyapatite (HA) coating on a metallic implant, impregnated with antibiotics, as a potential solution. They introduce a novel drug loading strategy using chitosan microspheres and gelatin polymer, which allows for sustained drug release and controlled diffusion. The study found that this approach improved tribological properties, antibacterial efficacy, and cytocompatibility compared to regular HA coated surfaces. [Extracted from the article]

A study conducted by researchers at Southwest University of Science and Technology in Mianyang, China, explores the use of hydroxyapatite coatings to reduce the corrosion rate of magnesium alloys, which are used as bone implant materials. The researchers propose using femtosecond laser construction of microemulsion cone structures on the surface of magnesium alloys to enhance the density, thickness, and bonding strength of the coatings. This method successfully controls the corrosion rate of magnesium alloys, making them more suitable for clinical applications. The study was published in the Chemical Engineering Journal and has been peer-reviewed. [Extracted from the article]

The article presents research from the University of Malaya on the development and characterization of bio-functional coatings for titanium implants. Topics discussed include the application of hydroxyapatite and fluorapatite coatings using plasma electrolytic oxidation on selectively laser melted titanium scaffolds, the enhancement of implant biocompatibility, and the potential use of this technique in orthopedic applications for improved mechanical properties.

The article focuses on new research from the Faculty of Sciences at the University of Gafsa on the physico-chemical properties of copper-doped hydroxyapatite coatings. Topics include the evaluation of antibacterial activity, the biocompatibility of hydroxyapatite and copper-doped coatings, and their effectiveness in inhibiting biofilm formation by Pseudomonas aeruginosa.

A recent study conducted at Punjabi University Patiala focused on the use of hydroxyapatite (HAp) coatings on metallic biomaterials. The researchers found that HAp is a biocompatible ceramic biomaterial that can enhance the crystallinity and adhesion quality of metallic biomaterials when applied using thermal spray techniques. The study also examined the bioactivity and corrosion behavior of the HAp coatings. The findings contribute to a better understanding of the mechanisms and advancements in bioactivity and corrosion analysis of these coatings. For more information, readers can refer to the Journal of Electrochemical Science and Engineering. [Extracted from the article]

A recent study conducted by investigators from Andalas University in Padang, Indonesia, examined the effect of Hydroxyapatite (HA) coating thickness on inflammation and osseointegration properties of Ti-29Nb-13Ta-4.6Zr (TNTZ) implants for orthopedic applications. The study found that the optimal thickness of the HA layer was in the medium range (70-90 μm), resulting in low inflammation levels, relatively high osseointegration rates, and optimal new bone tissue growth. These findings have potential applications in future orthopedic implant development. The research was supported by the LPPM of Universitas Andalas. [Extracted from the article]

A recent study conducted by researchers at Nanjing University of Science and Technology in China explored the biomineralization ability of magnesium-doped coral hydroxyapatite coating. The researchers found that the heat-treated magnesium-doped coral hydroxyapatite films exhibited superior biomineralization properties. The study suggests that the magnesium undergoes chemical corrosion in simulated body fluid, leading to the formation of porous structures and the development of an apatite-like layer. This research contributes to the understanding of materials that could potentially be used in bone conduction frameworks. [Extracted from the article]

Researchers from the Bulgarian Academy of Sciences have developed a new method for creating porous poly lactic acid (PLA)-based scaffolds for bone tissue regeneration. The scaffolds were designed using a femtosecond laser to induce microstructuring and were further functionalized with a nanometric layer of hydroxyapatite (HA) using the pulse laser deposition (PLD) method. The researchers conducted various analyses and cytocompatibility studies to evaluate the effectiveness of the scaffolds, and found that the laser-created grooves on the scaffolds promoted cell orientation and elongation, potentially improving their application in personalized bone tissue engineering. This research has been peer-reviewed and published in Optical and Quantum Electronics. [Extracted from the article]

A study conducted at Zhumadian Central Hospital in China has developed a new nanocomposite material for treating osteoporotic bone defects. The material, called SrHAp/GO/LZ, is a coating made of strontium, hydroxyapatite, graphene oxide, and linezolid. The coating has antibacterial properties, drug delivery capabilities, and improved mechanical characteristics. The study found that the SrHAp/GO/LZ coating enhanced osteoblast proliferation and differentiation, inhibited bacterial growth, and improved cell adhesion, proliferation, and differentiation. This research provides a promising approach for the treatment and prevention of osteoporotic bone defects. [Extracted from the article]

A recent study conducted by researchers at APJ Abdul Kalam Technological University in Kerala, India, explored the surface characteristics of a bioimplant material called Ti6Al4V and its impact on osteoblast cell adhesion and bacterial adhesion. The researchers used laser irradiation, laser texturing, and hydroxyapatite (HAp) coating to modify the surface of the Ti alloy. The results showed that the modified surfaces had improved osteointegration and antibacterial properties compared to the unmodified surfaces. The researchers attributed this to the surface chemistry, topography, and hydrophilicity of the modified surfaces. The study suggests that surface modification techniques can enhance the performance of bioimplants. [Extracted from the article]

A recent study conducted at Zuyderland Medical Center in Geleen, Netherlands, evaluated the long-term survival of two types of cementless total hip arthroplasties (THAs) called Anatomic Benoist Gerard (ABG) I and II. The study followed 198 patients (212 THAs) for a mean of 11.3 years and found that the overall survival rate was 95.5%, with 11 patients requiring revision surgery. There was no significant difference in survival between the ABG I and II THAs. The study concluded that both types of anatomically adapted hydroxyapatite coated cementless THAs showed excellent survival at more than 11 years of follow-up. [Extracted from the article]

A recent study conducted by researchers at Central South University in Changsha, China, explores the use of biomimetic metallic implant surfaces to enhance osseointegration, the process of bone growth around implants. The researchers synthesized a micro/nano hierarchical SrSi-codoped hydroxyapatite coating on a zirconium alloy, which exhibited excellent hydrophilicity and promoted the adhesion of proteins and cells. The coating also released Sr and Si, which stimulated the secretion of osteogenesis-related proteins and angiogenesis-related factors, promoting both bone growth and blood vessel formation. The study concludes that this coating, combining structural and compositional biomimicry, shows promise as a candidate for implant materials. [Extracted from the article]

• A coating with pores of several microns in diameter is created through micro arc oxidation (MAO) on the surface of the gradient porous Ti 3 Zr 2 Sn 3 Mo 25 Nb alloy with larger pores of hundreds microns fabricated from powder sintering on the solid alloyed core. • The MAO treatment in an electrolyte containing Ca and P enables the secondary microporous coating contained hydroxyapatite (HA), and the bone morphogenetic protein-2 (BMP-2) was further loaded on to the coating (HA+BMP). • Both HA and BMP-2 on the surface and inside pores significantly activate the bioactive of the alloy by promoting the formation of new bone tissue on the surface and stimulating new bone tissue to growth into the gradient porous Ti 3Zr2Sn3Mo25Nb alloy. • The interfacial shear strength of the coatings with HA or HA+BMP is higher than that of the coating without both HA or BMP-2 at all time after implantation, the strength in the HA+BMP coating is highest in the three coatings and is about three times of the strength of the CPT sample in all the testing implantation intervals. The gradient porous Ti3Zr2Sn3Mo25Nb (TLM) alloy rods were fabricated through sintering the alloyed powder to a solid core. The porous sample was then modified by a Micro Arc Oxidation (MAO) treatment in an electrolyte containing calcium and phosphate, a hydrothermal treatment enabled secondary microporous hydroxyapatite (HA) coating, and a further bone morphogenetic protein-2 (BMP-2) loading treatment through immersion and freeze-drying. The treatment led to an orderly secondary microporous coating containing HA nano-particles and evenly distributed BMP-2 in the porous coatings. As a result, osteoblasts could adhere and grow well on the coatings with a high cell adhesion rate and cell functional activity. The in-situ shear testing indicated that the interfacial strength had been enhanced significantly. Improvement of the bond formation and osseointegration with the titanium implant is attributed to increased surface area for the cell to attach, creating voids for the cell to grow in, and activating titanium surface by introducing bioactive ingredients such as HA and BMP-2. [Display omitted] [ABSTRACT FROM AUTHOR]

[Display omitted] • Titanium was functionalized by bionic micro/nano-structure and Sr-HA coating. • Functionalized titanium could promote cell adhesion and inhibit osteoclast activity. • Functionalized titanium could improve the bone-implant bonding strength. As the population ages, more and more people are suffering from osteoarthritis (OA), resulting in an increasing requirement for joint implants. Surface modification to improve the topology and composition of the implants has been proved to be an effective way to improve the primary stability and long-term success rate of joint implants. In this work, a bionic micro/nano-structure accompanied with a strontium-substituted hydroxyapatite (SrHA) coating was fabricated on titanium (Ti) surface via electrochemical corrosion, ultrasonic treatment, and hydrothermal deposition methods. The in vitro study demonstrated that the bionic structure and the bioactive apatite could synergistically increase the expressions of integrin-related gene (ITG α5β1) and osteoblastic genes (Col-I and OCN), and thus promote osteoblast growth. In addition, owing to the anti-bone resorption property of Sr2+, the coating could effectively inhibit osteoclast differentiation and proliferation. In a word, the prepared samples not only promoted osteogenesis but also inhibited osteoclastogenesis. The in vivo experiment via a rabbit model found that the bionic structured surface provided the pore for new bone ingrowth, which was beneficial to the mechanical interlocking between the implant and bone. Moreover, the bionic structure and bioactive SrHA coating had a synergistic effect on promoting bone formation, osseointegration, and bone-implant bonding strength. This study therefore presented a new strategy to fabricate bio-functionalized Ti-based implants for potential application in orthopedics field. [ABSTRACT FROM AUTHOR]

A patent application by Orthex LLC for an improved half pin design for external fixators has been made available online. The invention aims to address the need for better management of skin and tissue hygiene control and protection, as well as improvements in fixator technology. The half pin is designed with a specific hydroxyapatite coating, variable thread pitch, and constant major diameter threads. It is not designed to be a cutting pin and is inserted in previously incised tissue and drilled channels in the bone. The patent application includes apparatus claims for orienting a bone fixation pin relative to an external fixator ring. [Extracted from the article]

A new study conducted by researchers at Sheffield Teaching Hospitals NHS Foundation Trust has found that the ARCOS Modular Femoral Revision System is effective in the medium term for patients undergoing total hip arthroplasty. The study followed 74 patients over a minimum of 5 years and found a 100% femoral survival rate with no revisions of the femoral component. Patients also showed consistent improvement in hip scores and quality of life measures. The system, which aims to preserve femoral bone stock, offers a range of options and avoids the need for conversion to an endoprosthetic. [Extracted from the article]

A study conducted by researchers from the University of Tabriz in Iran explores the electrophoretic deposition of composite coatings for drug delivery applications. The researchers investigated the electrical conductivity and pH variation of solutions and suspensions using different concentrations of acetic acid. The study found that composite coatings containing 50% mesoporous bioglass and 50% hydroxyapatite exhibited the highest rate of drug release. The research was supported by the Iran National Science Foundation and has been peer-reviewed. [Extracted from the article]

A recent report from Yale University New Haven Hospital discusses the use of Polyetheretherketone (PEEK) implants in craniofacial surgery for facial augmentation and reconstruction. While PEEK implants offer mechanical resilience and compatibility with imaging, their biologically inert nature can lead to complications. The report highlights the need for improved implant materials and explores surface and structural modifications, such as hydroxyapatite coating and porous structures, to enhance bioreactivity and reduce complications. The research concludes that future studies should focus on long-term stability and the potential benefits of surface modifications in craniofacial surgery. [Extracted from the article]

A patent application has been submitted for a new orthopedic implant that features a coating made of crystalline gallium-containing hydroxyapatite. This coating is designed to improve bone growth and biological fixation. The current methods of coating implants with hydroxyapatite have limitations, such as uneven degradation and weak adhesion. The new coating aims to overcome these issues by incorporating gallium ions into the hydroxyapatite lattice, resulting in a conformal coating that degrades uniformly over several weeks without producing particles. The coating also has a small crystallite size, which further enhances its properties. The patent application provides detailed technical information about the implant's characteristics and manufacturing process. [Extracted from the article]

Ossdsign AB, a company based in Uppsala, Sweden, has been issued a patent for bone implants and methods for correcting bone defects. The patent describes the use of wire mesh support frames and biocompatible plates to fill large bone defects, such as those in the cranium or long bones. The implants can be customized for each patient and are designed to provide structural support for new bone growth. The patent also discusses the use of hydroxyapatite coating and ceramic materials to enhance bone formation. This invention offers a potential solution to the challenges associated with current strategies for correcting bone defects. [Extracted from the article]

Howmedica Osteonics Corp. has been issued a patent for a filamentary fixation device. Traditional fixation devices, such as suture anchors, are typically made of metal or hard plastic and can be large in diameter, limiting their implantation locations in the body. The present invention is a soft fixation device constructed of filamentary material, such as suture or thread, which provides high pull-out strength while requiring a smaller surgical site compared to traditional devices. The patent includes various embodiments of the device, methods of insertion, and related instrumentation, systems, and kits. [Extracted from the article]

A recent study conducted in the Russian Federation explored the use of a biodegradable polycaprolactone implant coated with hydroxyapatite for the treatment of osteochondral defects in rats. The study found that the implant significantly improved range of motion and ensured the integrity of the articular surface. Additionally, the implant promoted cell growth and directed differentiation in the area of the defect. The researchers concluded that the implant may be effective for repairing osteochondral defects. Further information on the study can be found in the journal article "Bioactive biodegradable polycaprolactone implant for management of osteochondral defects: an experimental study." [Extracted from the article]

Researchers at the Leibniz Institute for Solid State and Materials Research in Dresden, Germany, have developed a new method for incorporating gallium ions into hydroxyapatite coatings on a low modulus beta Ti-45Nb alloy. These coatings have the potential to reduce bacterial infections on implant surfaces. The study found that the gallium-containing coatings maintained their morphology and composition, with gallium ions present on the surface up to 1 wt.%. This research shows promise for the local delivery of gallium ions during bone regeneration, providing antibacterial protection without the use of antibiotics or growth factors. [Extracted from the article]

A recent study conducted at Islamic Azad University in Ardebil, Iran, focused on improving bone regeneration through tissue engineering. The researchers used electrospinning to create scaffolds made of polycaprolactone (PCL), collagen (COL), and polyvinyl pyrrolidone (PVP). They added different concentrations of the antibiotic Cephalexin (CEF) and coated the scaffolds with hydroxyapatite (HA). The study found that the PCL/COL: PVP scaffold loaded with 1.5% CEF and coated with 2% HA showed promising results for bone regeneration, demonstrating antibacterial properties and sustained release capabilities. Further evaluation is needed for potential applications in bone regeneration. [Extracted from the article]

Researchers from Nantong University in the People's Republic of China have conducted a study on the preparation of hydroxyapatite coated porous carbon nanofibers (PCNFs) for loading dexamethasone (DEX) and enhancing the differentiation ability of bone mesenchymal stem cells (BMSCs). The study found that the HA-coated PCNFs showed improved biocompatibility and optimized osteoconductivity, leading to increased cell viability, alkaline phosphatase activity, calcium nodule secretion ability, and RUNX2 protein expression. The researchers concluded that these novel DEX-loaded and HA-coated PCNFs have potential applications in bone tissue regeneration. This research was supported by various funding sources, including the National Natural Science Foundation of China and Nantong University. [Extracted from the article]

A recent report from Philipps-University Marburg in Germany discusses the importance of preventing tooth decay in dentistry. The study focuses on the role of the "pellicle," a layer of saliva proteins on the surface of teeth, in caries prevention. The researchers developed an analytical tooth model using surface plasmon resonance chips coated with hydroxyapatite to investigate the pellicle. They found that even slight acid solutions can damage the pellicle within seconds, potentially leading to tooth decay. The model also allows for the study of the influence of beverages on the pellicle. This research provides valuable insights into the formation and degradation of the pellicle and its impact on oral health. [Extracted from the article]

Researchers from Glasgow Caledonian University have published a report on their findings regarding arthroplasty, specifically the survival and complications of the uncemented hydroxyapatite (HA) coated Trident II acetabular component in total hip arthroplasty (THA). The study aims to assess the long-term outcomes of this component, including joint-specific function, health-related quality of life, and radiological signs of loosening. The research will involve a prospective cohort study of 125 implants, with functional and radiological assessments performed up to ten years following THA. The results of this study will provide valuable data to inform the ongoing use of the HA acetabulum in orthopedic practice. [Extracted from the article]

A patent has been issued for an orthopedic implant with a crystalline gallium-containing hydroxyapatite coating. The coating is designed to enhance bone growth and biological fixation. Previous methods of coating implants with hydroxyapatite have had limitations, such as non-uniform degradation and poor adhesion. The new coating addresses these issues by incorporating gallium ions and achieving a crystalline structure. The patent provides detailed descriptions and claims for different embodiments of the orthopedic implant. [Extracted from the article]

Keywords for this news article include: Trinity College Dublin, Dublin, Ireland, Europe, Minerals, Phosphates, Orthopedics, Hydroxyapatites, Phosphoric Acids, Health and Medicine, Chemicals and Chemistry. Keywords: Apatites; Chemicals and Chemistry; Health and Medicine; Hydroxyapatites; Minerals; Orthopedics; Phosphates; Phosphoric Acids EN Apatites Chemicals and Chemistry Health and Medicine Hydroxyapatites Minerals Orthopedics Phosphates Phosphoric Acids 5159 5159 1 10/09/23 20231013 NES 231013 2023 OCT 13 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on chemicals and chemistry are discussed in a new report. [Extracted from the article]

Keywords: Apatites; Chemicals and Chemistry; Health and Medicine; Hydroxyapatites; Minerals; Orthopedics; Phosphates; Phosphoric Acids EN Apatites Chemicals and Chemistry Health and Medicine Hydroxyapatites Minerals Orthopedics Phosphates Phosphoric Acids 2246 2246 1 10/09/23 20231013 NES 231013 2023 OCT 13 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on chemicals and chemistry have been presented. For more information on this research see: Development of Hydroxyapatite Coatings for Orthopaedic Implants from Colloidal Solutions: Part 1-Effect of Solution Concentration and Deposition Kinetics. [Extracted from the article]

Keywords: Apatites; Hydroxyapatites; Light Metals; Magnesium; Minerals; Phosphates; Phosphoric Acids; Science EN Apatites Hydroxyapatites Light Metals Magnesium Minerals Phosphates Phosphoric Acids Science 521 521 1 10/09/23 20231012 NES 231012 2023 OCT 12 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Investigators publish new report on science. Apatites, Hydroxyapatites, Light Metals, Magnesium, Minerals, Phosphates, Phosphoric Acids, Science. [Extracted from the article]

Keywords: Apatites; Hydroxyapatites; Light Metals; Magnesium; Materials Research; Minerals; Phosphates; Phosphoric Acids; Technology EN Apatites Hydroxyapatites Light Metals Magnesium Materials Research Minerals Phosphates Phosphoric Acids Technology 1051 1051 1 09/04/23 20230908 NES 230908 2023 SEP 10 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Current study results on materials research have been published. Apatites, Hydroxyapatites, Light Metals, Magnesium, Materials Research, Minerals, Phosphates, Phosphoric Acids, Technology. [Extracted from the article]

Apatites, Chemicals, Electrochemicals, Hydroxyapatites, Minerals, Phosphates, Phosphoric Acids Keywords: Apatites; Chemicals; Electrochemicals; Hydroxyapatites; Minerals; Phosphates; Phosphoric Acids EN Apatites Chemicals Electrochemicals Hydroxyapatites Minerals Phosphates Phosphoric Acids 132 132 1 08/28/23 20230831 NES 230831 2023 AUG 31 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- A new study on minerals is now available. [Extracted from the article]

Apatites, Bone Research, Health and Medicine, Hydroxyapatites, Minerals, Phosphates, Phosphoric Acids Keywords: Apatites; Bone Research; Health and Medicine; Hydroxyapatites; Minerals; Phosphates; Phosphoric Acids EN Apatites Bone Research Health and Medicine Hydroxyapatites Minerals Phosphates Phosphoric Acids 577 577 1 08/14/23 20230817 NES 230817 2023 AUG 17 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Data detailed on bone research have been presented. [Extracted from the article]

Keywords: Jinan; People's Republic of China; Asia; Biotechnology; Apatites; Hydroxyapatites; Minerals; Phosphates; Phosphoric Acids EN Jinan People's Republic of China Asia Biotechnology Apatites Hydroxyapatites Minerals Phosphates Phosphoric Acids 126 126 1 08/07/23 20230810 NES 230810 2023 AUG 10 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- New research on Biotechnology is the subject of a report. Keywords for this news article include: Jinan, People's Republic of China, Asia, Biotechnology, Apatites, Hydroxyapatites, Minerals, Phosphates, Phosphoric Acids, Shandong University. Jinan, People's Republic of China, Asia, Biotechnology, Apatites, Hydroxyapatites, Minerals, Phosphates, Phosphoric Acids. [Extracted from the article]

Apatites, Bone Research, Business, Health and Medicine, Hydroxyapatites, Hygiene, Minerals, Orthex LLC, Phosphates, Phosphoric Acids Keywords: Apatites; Bone Research; Business; Health and Medicine; Hydroxyapatites; Hygiene; Minerals; Orthex LLC; Phosphates; Phosphoric Acids EN Apatites Bone Research Business Health and Medicine Hydroxyapatites Hygiene Minerals Orthex LLC Phosphates Phosphoric Acids 9814 9814 1 07/17/23 20230721 NES 230721 2023 JUL 21 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Orthex LLC (Warsaw, Indiana, United States) has been issued patent number 11684399, according to news reporting originating out of Alexandria, Virginia, by NewsRx editors. Ideally, the half pins are not designed to be cutting pins but are inserted in previously incised tissue and drilled channels in the bone or bones as needed, and therefore the tips of the half pins are never sharp, so a to avoid pain sensation within a patient should a half pin tip protrude from its bone into the adjacent muscle, fascia or tissue adjacent the bone. [Extracted from the article]

Compared with the HA coating, the Se-HA coating effectively promoted the adhesion, proliferation, and differentiation of osteoblasts in the presence of fluoride ions." Energy-dispersive x-ray spectroscopy, x-ray photoelectron spectroscopy, and x-ray powder diffraction demonstrated the homogeneous presence of Se within a Se-HA coating made from the appropriately doped powder. [Extracted from the article]

Taiyuan, People's Republic of China, Asia, Chemicals and Chemistry, Apatites, Dentistry, Health and Medicine, Hydroxyapatites, Light Metals, Minerals, Phosphates, Phosphoric Acids, Titanium Keywords: Taiyuan; People's Republic of China; Asia; Chemicals and Chemistry; Apatites; Dentistry; Health and Medicine; Hydroxyapatites; Light Metals; Minerals; Phosphates; Phosphoric Acids; Titanium EN Taiyuan People's Republic of China Asia Chemicals and Chemistry Apatites Dentistry Health and Medicine Hydroxyapatites Light Metals Minerals Phosphates Phosphoric Acids Titanium 1308 1308 1 04/10/23 20230414 NES 230414 2023 APR 14 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on Chemicals and Chemistry are discussed in a new report. [Extracted from the article]

Keywords: Apatites; Chemicals and Chemistry; Dentistry; Health and Medicine; Hydroxyapatites; Minerals; Phosphates; Phosphoric Acids EN Apatites Chemicals and Chemistry Dentistry Health and Medicine Hydroxyapatites Minerals Phosphates Phosphoric Acids 5547 5547 1 04/03/23 20230407 NES 230407 2023 APR 7 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on chemicals and chemistry. Keywords for this news article include: University of Aveiro, Aveiro, Portugal, Europe, Minerals, Dentistry, Phosphates, Hydroxyapatites, Phosphoric Acids, Health and Medicine, Chemicals and Chemistry. Apatites, Chemicals and Chemistry, Dentistry, Health and Medicine, Hydroxyapatites, Minerals, Phosphates, Phosphoric Acids. [Extracted from the article]

Keywords: Alkaline Earth Metals; Apatites; Bone Research; Drugs and Therapies; Health and Medicine; Hydroxyapatites; Light Metals; Magnesium; Minerals; Molecular Science; Phosphates; Phosphoric Acids; Science; Strontium; Titanium EN Alkaline Earth Metals Apatites Bone Research Drugs and Therapies Health and Medicine Hydroxyapatites Light Metals Magnesium Minerals Molecular Science Phosphates Phosphoric Acids Science Strontium Titanium 1004 1004 1 03/27/23 20230331 NES 230331 2023 MAR 31 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New study results on molecular science have been published. For more information on this research see: Vapor-Induced Pore-Forming Atmospheric-Plasma-Sprayed Zinc-, Strontium-, and Magnesium-Doped Hydroxyapatite Coatings on Titanium Implants Enhance New Bone Formation-An In Vivo and In Vitro Investigation. [Extracted from the article]

Keywords for this news article include: Tainan, Taiwan, Asia, Gelatin, Health and Medicine, Medical Devices, Orthopedic Implant, Proteins, Scleroproteins, Surgery, Surgical Technology, National Cheng Kung University. Keywords: Tainan; Taiwan; Asia; Gelatin; Health and Medicine; Medical Devices; Orthopedic Implant; Proteins; Scleroproteins; Surgery; Surgical Technology EN Tainan Taiwan Asia Gelatin Health and Medicine Medical Devices Orthopedic Implant Proteins Scleroproteins Surgery Surgical Technology 384 384 1 03/23/23 20230324 NES 230324 2023 MAR 26 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Research findings on Surgical Technology - Orthopedic Implant are discussed in a new report. [Extracted from the article]

Keywords: Alkaline Earth Metals; Apatites; Bone Research; Cell Proliferation; Connective Tissue Cells; Dentistry; Health and Medicine; Hydroxyapatites; Light Metals; Minerals; Osteoblasts; Phosphates; Phosphoric Acids; Strontium; Tantalum; Titanium; Transition Elements EN Alkaline Earth Metals Apatites Bone Research Cell Proliferation Connective Tissue Cells Dentistry Health and Medicine Hydroxyapatites Light Metals Minerals Osteoblasts Phosphates Phosphoric Acids Strontium Tantalum Titanium Transition Elements 1752 1752 1 03/23/23 20230303 NES 230303 2023 MAR 3 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in alkaline earth metals. The MG63 cell culture assay results indicated that due to the incorporation of strontium ions along with tantalum embedded in HA, cell proliferation increased significantly after a 48 h study.". [Extracted from the article]

Keywords: Giza; Egypt; Africa; Apatites; Bioengineering; Biomedical Engineering; Biomedicine; Biotechnology; Chemicals; Electrochemicals; Health and Medicine; Hydroxyapatites; Minerals; Nanohydroxyapatite; Nanotechnology; Phosphates; Phosphoric Acids; Regenerative Medicine EN Giza Egypt Africa Apatites Bioengineering Biomedical Engineering Biomedicine Biotechnology Chemicals Electrochemicals Health and Medicine Hydroxyapatites Minerals Nanohydroxyapatite Nanotechnology Phosphates Phosphoric Acids Regenerative Medicine 2023 FEB 23 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Current study results on Biomedical Engineering - Regenerative Medicine have been published. These corrosion outcomes and the fruitful deposition of a hydroxyapatite/chitosan composite coating on zinc substrate indicate that the coating is efficient for the creation of new composite coatings for either functional implants or regenerative medicine." Keywords for this news article include: Giza, Egypt, Africa, Apatites, Bioengineering, Biomedical Engineering, Biomedicine, Biotechnology, Chemicals, Electrochemicals, Health and Medicine, Hydroxyapatites, Minerals, Nanohydroxyapatite, Nanotechnology, Phosphates, Phosphoric Acids, Regenerative Medicine, Cairo University. [Extracted from the article]

The present results demonstrated that the key molecules of phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT) and mammalian target of rapamycin (mTOR) were activated after the biomimetic hydroxyapatite coating were constructed on the 3D-printed ceramic scaffolds. Keywords: Guangzhou; People's Republic of China; Asia; Apatites; Bioengineering; Biomedical Engineering; Biomedicine; Biomimetics; Bionanotechnology; Biotechnology; Bone Regeneration; Bone Research; Bone Substitutes; Emerging Technologies; Enzymes and Coenzymes; Health and Medicine; Hydroxyapatites; Kinase; Minerals; Nanobiotechnology; Nanotechnology; Phosphates; Phosphoric Acids; Regenerative Medicine; Tissue Engineering EN Guangzhou People's Republic of China Asia Apatites Bioengineering Biomedical Engineering Biomedicine Biomimetics Bionanotechnology Biotechnology Bone Regeneration Bone Research Bone Substitutes Emerging Technologies Enzymes and Coenzymes Health and Medicine Hydroxyapatites Kinase Minerals Nanobiotechnology Nanotechnology Phosphates Phosphoric Acids Regenerative Medicine Tissue Engineering 2023 FEB 16 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Investigators publish new report on Biomedical Engineering - Tissue Engineering. [Extracted from the article]

Keywords: Roorkee; India; Asia; Apatites; Bioengineering; Biomedical Engineering; Biomedicine; Biotechnology; Bone Regeneration; Bone Research; Bone Substitutes; Bone-Tissue Engineering; Engineering; Health and Medicine; Hydroxyapatites; Minerals; Phosphates; Phosphoric Acids; Tissue Engineering EN Roorkee India Asia Apatites Bioengineering Biomedical Engineering Biomedicine Biotechnology Bone Regeneration Bone Research Bone Substitutes Bone-Tissue Engineering Engineering Health and Medicine Hydroxyapatites Minerals Phosphates Phosphoric Acids Tissue Engineering 2023 FEB 16 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Current study results on Biomedical Engineering - Tissue Engineering have been published. Roorkee, India, Asia, Apatites, Bioengineering, Biomedical Engineering, Biomedicine, Biotechnology, Bone Regeneration, Bone Research, Bone Substitutes, Bone-Tissue Engineering, Engineering, Health and Medicine, Hydroxyapatites, Minerals, Phosphates, Phosphoric Acids, Tissue Engineering. [Extracted from the article]

Our news editors obtained a quote from the research from Saga University: "The Ag-HA-coated total hip prosthesis, which combines the antibacterial activity of Ag and the osteoconductivity of HA, is the first antibacterial cementless total hip prosthesis worldwide. Keywords: Apatites; Arthroplasty; Drugs and Therapies; Health and Medicine; Hydroxyapatites; Medical Devices; Minerals; Orthopedic Procedures; Orthopedics; Phosphates; Phosphoric Acids; Prosthetics; Surgery EN Apatites Arthroplasty Drugs and Therapies Health and Medicine Hydroxyapatites Medical Devices Minerals Orthopedic Procedures Orthopedics Phosphates Phosphoric Acids Prosthetics Surgery 2023 FEB 10 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Research findings on arthroplasty are discussed in a new report. [Extracted from the article]

Apatites, Bioengineering, Biomedical Engineering, Biomedicine, Biotechnology, Health and Medicine, Hydroxyapatites, Light Metals, Minerals, Phosphates, Phosphoric Acids, Regenerative Medicine, Titanium Keywords: Apatites; Bioengineering; Biomedical Engineering; Biomedicine; Biotechnology; Health and Medicine; Hydroxyapatites; Light Metals; Minerals; Phosphates; Phosphoric Acids; Regenerative Medicine; Titanium EN Apatites Bioengineering Biomedical Engineering Biomedicine Biotechnology Health and Medicine Hydroxyapatites Light Metals Minerals Phosphates Phosphoric Acids Regenerative Medicine Titanium 2023 FEB 9 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Imaging Week -- New research on regenerative medicine is the subject of a new report. [Extracted from the article]