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The article reflects on the use of embryos and larvae of zebrafish in cancer biology and in the research work to understand the development of cancer. It informs that zebra fishes are susceptible to the tumors of brain, nervous system and liver and thus are widely used as a modal organism in cancer related studies. It highlights that zebra fish also plays an important role in drug discovery and in the development of cancer diagnostic methods.

The article discusses a technique by biophysicist Philipp Keller and colleagues that combines light-sheet microscopy with computational strategies to record the emergence of early structure in embryos, cell by cell. Topics include biophysicist Ernst Stelzer and colleagues' demonstration of the potential of light-sheet microscopy in developmental biology and Keller and colleagues' recordings of nervous system development in zebra-fish embyros and digitally reconstructed full fruit fly embryos.

The article looks at a report published in "Current Biology" by geneticist Koichi Kawakami and team on the use of genetically engineered green fluorescent proteins (GFPs) to track neuronal activity in the vision-processing tectum region of the zebrafish larvae brain. A visuotopic map was created of the movements of brain signalling corresponding to movements of a blinking dot near the fish. Particular focus is given to the sensitivity of visual perception of horizontal or vertical movements.

The article presents biologist members' narratives on their own work in their respective fields. It includes a view of cytokinesis of zebra danio fish during embryogenesis, a view of toxicology and drug development in British company GW Pharmaceuticals, and a view of bioethics in Durham University, England.

The article discusses why the zebrafish (Danio rerio) is becoming scientists' favorite animal model in research. Topics include the increased use of zebrafish as animal models of human diseases following the successful selective mutation of their DNA by scientists in 1988, the benefits of using larval zebrafish in research, such as the transparency of the embryos which allows researchers to watch their organs grow, and the three major advantages of zebrafish over rodents. INSET: Smog Log.