1. Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome
- Author
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Bao-yan, Liu, Jing-qing, Hu, Yan-ming, Xie, Wei-liang, Weng, Rong-bing, Wang, Yan-ping, Zhang, Xiu-hui, Li, Ke, Zhang, Ai-ming, Ren, Jun, Li, Bao-guo, Wang, Xu-dong, Tang, Wei-dong, Wang, Qing, Ni, Jin-ping, Zhang, Hong-jin, Wu, Wei, Zhou, Zhi, Geng, Yang-bo, He, Zhi-wei, Liang, Li-yun, He, Fan-zhu, Gao, and Jin, Peng
- Abstract
Objective: To evaluate the effects of treatment of integrative Chinese and Western medicine (ICWM) on arterial oxygen saturation (SaO2) in patients with severe acute respiratory syndrome (SARS).Methods:The non-randomized, controlled trial was conducted on 447 SARS patients treated synchronously with western conventional treatment (WM group,n= 171) alone and ICWM (ICWM group,n= 276). The changes of the cases with normal level (≥95%) or abnormal level (<95%) SaO2were observed dynamically.Results: In the 3rd-14th day of the therapeutic course, the percentage of patients with normal SaO2 in the ICWM group was higher than that in the WM group (OR = 0. 5178,P= 0.0038), and this tendency was more evident in patients of the severe type (OR = 0.18,P= 0.0001). However, the statistical significance of difference was only shown in patients for whom the ICWM treatment started in the early period after the onset (<-7 days after it, OR = 0.3803,P= 0.006), but not shown in those who received ICWM treatment later in the mid-late period of SARS (P>0.05).Conclusion: ICWM treatment, particularly when it is used for intervention in the early stage, is beneficial for maintaining normal SaO2in SARS patients.
- Published
- 2004
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