Search

The present hyperpolarized MR imaging animal study has shown detection of local metabolic changes is possible in a myocardial ischemia-reperfusion model and has enabled us to identify an acute increase in the lactate-to-bicarbonate ratio in the area at risk after reperfusion, with recovery to the baseline level by 1 week.

First-pass myocardial perfusion cardiovascular magnetic resonance (CMR) imaging yields high diagnostic accuracy for the detection of coronary artery disease (CAD). However, standard 2D multislice CMR perfusion techniques provide only limited cardiac coverage, and hence considerable assumptions are required to assess myocardial ischemic burden. The aim of this prospective study was to assess the diagnostic performance of 3D myocardial perfusion CMR to detect functionally relevant CAD with fractional flow reserve (FFR) as a reference standard in a multicenter setting.