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1. Role of Endogenous Vascular Endothelial Growth Factor in Tubular Cell Protection Against Acute Cyclosporine Toxicity1

Author

Arroyo, María Victoria Alvarez, Suzuki, Yusuke, Yagüe, Susana, Lorz, Corina, Jiménez, Sonsoles, Soto, Carlos, Barat, Antonio, Belda, Emilia, González-Pacheco, Francisco R., Deudero, Juan J. P., Castilla, María Ángeles, Egido, Jesús, Ortiz, Alberto, and Caramelo, Carlos

Abstract

Recent studies have shown that exogenous administration of vascular endothelial growth factor (VEGF) is protective against cyclosporine A (CsA) renal toxicity. No data are available, however, on the possible role of endogenous VEGF. Our objective was to examine whether endogenous VEGF has a significant role in the renal response against CsA toxicity.

Published
2002

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