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Cites a study from Italy which evaluates the ability of Urotensin II (U-II) to induce plasma extravasation in mice via UT receptor activation. Role of peptide Urotensin II in cardiovascular functions; Methods used to quantify plasma extravasation; Suggestion on the application of plasma extravasation assay as useful tool in characterizing the pharmalogical features of novel Urotensin receptor ligands in vivo.